Plant-made vaccine antigens and biopharmaceuticals
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Morens, 2004, The challenge of emerging and re-emerging infectious diseases, Nature, 430, 242, 10.1038/nature02759
Xu, 2007, Protecting households from catastrophic health spending, Health Aff., 26, 972, 10.1377/hlthaff.26.4.972
Davoodi-Semiromi, 2009, The green vaccine: a global strategy to combat infectious and autoimmune diseases, Hum. Vaccin., 5, 488, 10.4161/hv.8247
Moravec, 2007, Production of Escherichia coli heat labile toxin (LT) B subunit in soybean seed and analysis of its immunogenicity as an oral vaccine, Vaccine, 25, 1647, 10.1016/j.vaccine.2006.11.010
Glenz, 2006, Production of a recombinant bacterial lipoprotein in higher plant chloroplasts, Nat. Biotechnol., 24, 76, 10.1038/nbt1170
Arntzen, 2008, Plant science. Using tobacco to treat cancer, Science, 321, 1052, 10.1126/science.1163420
Yusibov, 2008, Recent progress in the development of plant derived vaccines, Expert Rev. Vaccines, 7, 1173, 10.1586/14760584.7.8.1173
Aviezer, 2009, A plant-derived recombinant human glucocerebrosidase enzyme – a preclinical and phase I investigation, PLoS ONE, 4, e4792, 10.1371/journal.pone.0004792
Biolex Therapeutics (2009) Biolex therapeutics researchers present Locteron® U.S. phase 2a hepatitis C trial results at EASL conference (http://www.biolex.com)
Shaaltiel, 2007, Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system, Plant Biotechnol. J., 5, 579, 10.1111/j.1467-7652.2007.00263.x
Mason, 1992, Expression of hepatitis B surface antigen in transgenic plants, Proc. Natl. Acad. Sci. U. S. A., 89, 11745, 10.1073/pnas.89.24.11745
Voinnet, 2003, An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus, Plant J., 33, 949, 10.1046/j.1365-313X.2003.01676.x
Arakawa, 1998, Efficacy of a food plant-based oral cholera toxin B subunit vaccine, Nat. Biotechnol., 16, 292, 10.1038/nbt0398-292
Tacket, 1998, Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato, Nat. Med., 4, 607, 10.1038/nm0598-607
Rosales-Mendoza, 2008, Ingestion of transgenic carrots expressing the Escherichia coli heat-labile enterotoxin B subunit protects mice against cholera toxin challenge, Plant Cell Rep., 27, 79, 10.1007/s00299-007-0439-z
Nochi, 2007, From the cover: rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination, Proc. Natl. Acad. Sci. U. S. A., 104, 10986, 10.1073/pnas.0703766104
Sandhu, 2000, Oral immunization of mice with transgenic tomato fruit expressing respiratory syncytial virus-F protein induces a systemic immune response, Transgenic Res., 9, 127, 10.1023/A:1008979525909
Richter, 2000, Production of hepatitis B surface antigen in transgenic plants for oral immunization, Nat. Biotechnol., 18, 1167, 10.1038/81153
Thanavala, 2005, Immunogenicity in humans of an edible vaccine for hepatitis B, Proc. Natl. Acad. Sci. U. S. A., 102, 3378, 10.1073/pnas.0409899102
Kong, 2001, Oral immunization with hepatitis B surface antigen expressed in transgenic plants, Proc. Natl. Acad. Sci. U. S. A., 98, 11539, 10.1073/pnas.191617598
Zhang, 2006, Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein, Plant Biotechnol. J., 4, 419, 10.1111/j.1467-7652.2006.00191.x
Lamphear, 2002, Delivery of subunit vaccines in maize seed, J. Control Release, 85, 169, 10.1016/S0168-3659(02)00282-1
Huang, 2006, Rapid, high-level production of hepatitis B core antigen in plant leaf and its immunogenicity in mice, Vaccine, 24, 2506, 10.1016/j.vaccine.2005.12.024
Huang, 2008, High-yield rapid production of hepatitis B surface antigen in plant leaf by a viral expression system, Plant Biotechnol. J., 6, 202, 10.1111/j.1467-7652.2007.00316.x
Santi, 2008, An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles, Vaccine, 26, 1846, 10.1016/j.vaccine.2008.01.053
Santi, 2006, Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression system, Proc. Natl. Acad. Sci. U. S. A., 103, 861, 10.1073/pnas.0510014103
Musiychuk, 2007, A launch vector for the production of vaccine antigens in plants, Influenza Other Respi. Viruses, 1, 19, 10.1111/j.1750-2659.2006.00005.x
Shoji, 2009, Plant-derived hemagglutinin protects ferrets against challenge infection with the A/Indonesia/05/05 strain of avian influenza, Vaccine, 27, 1087, 10.1016/j.vaccine.2008.11.108
D’Aoust, 2008, Influenza virus-like particles produced by transient expression in Nicotiana benthamiana induce a protective immune response against a lethal viral challenge in mice, Plant Biotechnol. J., 6, 930, 10.1111/j.1467-7652.2008.00384.x
Huang, 2009, A DNA replicon system for rapid high-level production of virus-like particles in plants, Biotechnol. Bioeng., 103, 706, 10.1002/bit.22299
Giritch, 2006, Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors, Proc. Natl. Acad. Sci. U. S. A., 103, 14701, 10.1073/pnas.0606631103
Zhang, 2006, Bean Yellow Dwarf Virus replicons for high-level transgene expression in transgenic plants and cell cultures, Biotechnol. Bioeng., 93, 271, 10.1002/bit.20695
Reggi, 2005, Recombinant human acid beta-glucosidase stored in tobacco seed is stable, active and taken up by human fibroblasts, Plant Mol. Biol., 57, 101, 10.1007/s11103-004-6832-x
Strasser, 2008, Generation of glyco-engineered Nicotiana benthamiana for the production of monoclonal antibodies with a homogeneous human-like N-glycan structure, Plant Biotechnol. J., 6, 392, 10.1111/j.1467-7652.2008.00330.x
Mett, 2007, Engineering and expression of the intracellular domain of insulinoma-associated tyrosine phosphatase (IA-2ic), a type 1 diabetes autoantigen, in plants, Transgenic Res., 16, 77, 10.1007/s11248-006-9033-3
Potula, 2008, Transient expression, purification and characterization of bioactive human fibroblast growth factor 8b in tobacco plants, Transgenic Res., 17, 19, 10.1007/s11248-007-9072-4
Wirth, 2004, Expression of active human epidermal growth factor (hEGF) in tobacco plants by integrative and non-integrative systems, Mol. Breed., 13, 23, 10.1023/B:MOLB.0000012329.74067.ca
Verma, 2007, Chloroplast vector systems for biotechnology applications, Plant Physiol., 145, 1129, 10.1104/pp.107.106690
Daniell, 2002, Molecular strategies for gene containment in transgenic crops, Nat. Biotechnol., 20, 581, 10.1038/nbt0602-581
Daniell, 2007, Transgene containment by maternal inheritance: effective or elusive? Proc, Natl. Acad. Sci. U. S. A., 104, 6879, 10.1073/pnas.0702219104
Arlen, 2007, Field production and functional evaluation of chloroplast-derived interferon-alpha2b, Plant Biotechnol. J., 5, 511, 10.1111/j.1467-7652.2007.00258.x
DeGray, 2001, Expression of an antimicrobial peptide via the chloroplast genome to control phytopathogenic bacteria and fungi, Plant Physiol., 127, 852, 10.1104/pp.010233
Oey, 2009, Plastid production of protein antibiotics against pneumonia via a new strategy for high-level expression of antimicrobial proteins, Proc. Natl. Acad. Sci. U. S. A., 106, 6579, 10.1073/pnas.0813146106
Surzycki, 2009, Factors effecting expression of vaccines in microalgae, Biologicals, 37, 133, 10.1016/j.biologicals.2009.02.005
Kumar, 2004, Plastid-expressed betaine aldehyde dehydrogenase gene in carrot cultured cells, roots, and leaves confers enhanced salt tolerance, Plant Physiol., 136, 2843, 10.1104/pp.104.045187
Zhou, 2008, High-level expression of human immunodeficiency virus antigens from the tobacco and tomato plastid genomes, Plant Biotechnol. J., 6, 897, 10.1111/j.1467-7652.2008.00356.x
Kanamoto, 2006, Efficient and stable transformation of Lactuca sativa L. cv. Cisco (lettuce) plastids, Transgenic Res, 15, 205, 10.1007/s11248-005-3997-2
Lelivelt, 2005, Stable plastid transformation in lettuce (Lactuca sativa L.), Plant Mol. Biol., 58, 763, 10.1007/s11103-005-7704-8
Ruhlman, 2007, Expression of cholera toxin B-proinsulin fusion protein in lettuce and tobacco chloroplasts – oral administration protects against development of insulitis in non-obese diabetic mice, Plant Biotechnol. J., 5, 495, 10.1111/j.1467-7652.2007.00259.x
Limaye, 2006, Receptor-mediated oral delivery of a bioencapsulated green fluorescent protein expressed in transgenic chloroplasts into the mouse circulatory system, FASEB J., 20, 959, 10.1096/fj.05-5134fje
Daniell, 2001, Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts, J. Mol. Biol., 311, 1001, 10.1006/jmbi.2001.4921
Molina, 2004, High-yield expression of a viral peptide animal vaccine in transgenic tobacco chloroplasts, Plant Biotechnol. J., 2, 141, 10.1046/j.1467-7652.2004.00057.x
Rosales-Mendoza, 2009, Expression of an Escherichia coli antigenic fusion protein comprising the heat labile toxin B subunit and the heat stable toxin, and its assembly as a functional oligomer in transplastomic tobacco plants, Plant J., 57, 45, 10.1111/j.1365-313X.2008.03666.x
Tregoning, 2005, Protection against tetanus toxin using a plant-based vaccine, Eur. J. Immunol., 35, 1320, 10.1002/eji.200425453
Koya, 2005, Plant-based vaccine: mice immunized with chloroplast-derived anthrax protective antigen survive anthrax lethal toxin challenge, Infect. Immun., 73, 8266, 10.1128/IAI.73.12.8266-8274.2005
Watson, 2004, Expression of Bacillus anthracis protective antigen in transgenic chloroplasts of tobacco, a non-food/feed crop, Vaccine, 22, 4374, 10.1016/j.vaccine.2004.01.069
Mett, 2007, A plant-produced plague vaccine candidate confers protection to monkeys, Vaccine, 25, 3014, 10.1016/j.vaccine.2007.01.017
Arlen, 2008, Effective plague vaccination via oral delivery of plant cells expressing F1-V antigens in chloroplasts, Infect. Immun., 76, 3640, 10.1128/IAI.00050-08
Molina, 2005, Induction of neutralizing antibodies by a tobacco chloroplast-derived vaccine based on a B cell epitope from canine parvovirus, Virology, 342, 266, 10.1016/j.virol.2005.08.009
Shao, 2008, The expression of classical swine fever virus structural protein E2 gene in tobacco chloroplasts for applying chloroplasts as bioreactors, C. R. Biol., 331, 179, 10.1016/j.crvi.2007.12.007
Skidmore, 2002, Overview of hepatitis E virus, Curr. Infect. Dis. Rep., 4, 118, 10.1007/s11908-002-0051-x
Zhou, 2006, A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice, World J. Gastroenterol., 12, 306, 10.3748/wjg.v12.i2.306
Fernandez-San Millan, 2008, Human papillomavirus L1 protein expressed in tobacco chloroplasts self-assembles into virus-like particles that are highly immunogenic, Plant Biotechnol. J., 6, 427, 10.1111/j.1467-7652.2008.00338.x
Lenzi, 2008, Translational fusion of chloroplast-expressed human papillomavirus type 16 L1 capsid protein enhances antigen accumulation in transplastomic tobacco, Transgenic Res., 17, 1091, 10.1007/s11248-008-9186-3
Chebolu, 2007, Stable expression of Gal/GalNAc lectin of Entamoeba histolytica in transgenic chloroplasts and immunogenicity in mice towards vaccine development for amoebiasis, Plant Biotechnol. J., 5, 230, 10.1111/j.1467-7652.2006.00234.x
Davoodi-Semiromi, A. et al. A green vaccine confers dual immunity against cholera and malaria by oral and injectable immunization. Plant Biotechnol. J. (in press)
Wang, 2008, A novel expression platform for the production of diabetes-associated autoantigen human glutamic acid decarboxylase (hGAD65), BMC Biotechnol., 8, 87, 10.1186/1472-6750-8-87
Staub, 2000, High-yield production of a human therapeutic protein in tobacco chloroplasts, Nat. Biotechnol., 18, 333, 10.1038/73796
Fernandez-San Millan, 2003, A chloroplast transgenic approach to hyper-express and purify human serum albumin, a protein highly susceptible to proteolytic degradation, Plant Biotechnol. J., 1, 71, 10.1046/j.1467-7652.2003.00008.x
Leelavathi, 2003, Chloroplast expression of His-tagged GUS-fusions: a general strategy to overproduce and purify foreign proteins using transplastomic plants as bioreactors, Mol. Breed., 11, 49, 10.1023/A:1022114427971
Nadai, 2008, High-level expression of active human alpha1-antitrypsin in transgenic tobacco chloroplasts, Transgenic Res., 18, 173, 10.1007/s11248-008-9209-0
Daniell, 2009, Optimization of codon composition and regulatory elements for expression of human insulin like growth factor-1 in transgenic chloroplasts and evaluation of structural identity and function, BMC Biotechnol., 9, 23, 10.1186/1472-6750-9-33
Green, 2009, Transient protein expression in three Pisum sativum (green pea) varieties, Biotechnol. J., 4, 230, 10.1002/biot.200800256
McCormick, 2008, Plant-produced idiotype vaccines for the treatment of non-Hodgkin's lymphoma: safety and immunogenicity in a phase I clinical study, Proc. Natl. Acad. Sci. U. S. A., 105, 10131, 10.1073/pnas.0803636105
O’Keefe, 2009, Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component, Proc. Natl. Acad. Sci. U. S. A., 106, 6099, 10.1073/pnas.0901506106
Tacket, 2000, Human immune responses to a novel Norwalk virus vaccine delivered in transgenic potatoes, J. Infect. Dis., 182, 302, 10.1086/315653
Tacket, 2004, Immunogenicity of recombinant LT-B delivered orally to humans in transgenic corn, Vaccine, 22, 4385, 10.1016/j.vaccine.2004.01.073
Yusibov, 2002, Expression in plants and immunogenicity of plant virus-based experimental rabies vaccine, Vaccine, 20, 3155, 10.1016/S0264-410X(02)00260-8
Jiang, 2007, Cholera toxin B protein in transgenic tomato fruit induces systemic immune response in mice, Transgenic Res., 16, 169, 10.1007/s11248-006-9023-5
Qian, 2008, Immunogenicity of recombinant hepatitis B virus surface antigen fused with preS1 epitopes expressed in rice seeds, Transgenic Res., 17, 621, 10.1007/s11248-007-9135-6
Dong, 2005, Oral immunization with pBsVP6-transgenic alfalfa protects mice against rotavirus infection, Virology, 339, 153, 10.1016/j.virol.2005.06.004
Li, 2006, Immunogenicity of a plant-derived edible rotavirus subunit vaccine transformed over fifty generations, Virology, 356, 171, 10.1016/j.virol.2006.07.045
Pogrebnyak, 2005, Severe acute respiratory syndrome (SARS) S protein production in plants: development of recombinant vaccine, Proc. Natl. Acad. Sci. U. S. A., 102, 9062, 10.1073/pnas.0503760102
Golovkin, 2007, Smallpox subunit vaccine produced in planta confers protection in mice, Proc. Natl. Acad. Sci. U. S. A., 104, 6864, 10.1073/pnas.0701451104
Wang, 2009, Generation and immunogenicity of Japanese encephalitis virus envelope protein expressed in transgenic rice, Biochem. Biophys. Res. Commun., 380, 292, 10.1016/j.bbrc.2009.01.061
Wang, 2008, Immunogenicity of Plasmodium yoelii merozoite surface protein 4/5 produced in transgenic plants, Int. J. Parasitol., 38, 103, 10.1016/j.ijpara.2007.06.005
Saejung, 2007, Production of dengue 2 envelope domain III in plant using TMV-based vector system, Vaccine, 25, 6646, 10.1016/j.vaccine.2007.06.029
Kim, 2008, Expression of human growth hormone in transgenic rice cell suspension culture, Plant Cell Rep., 27, 885, 10.1007/s00299-008-0514-0
Gutierrez-Ortega, 2005, Expression of functional interleukin-12 from mouse in transgenic tomato plants, Transgenic Res., 14, 877, 10.1007/s11248-005-1464-8
Bai, 2007, Expression and characteristic of synthetic human epidermal growth factor (hEGF) in transgenic tobacco plants, Biotechnol. Lett., 29, 2007, 10.1007/s10529-007-9438-y
Ding, 2006, High-level expression of basic fibroblast growth factor in transgenic soybean seeds and characterization of its biological activity, Biotechnol. Lett., 28, 869, 10.1007/s10529-006-9018-6
Wang, 2005, Production of biologically active GM-CSF in sugarcane: a secure biofactory, Transgenic Res., 14, 167, 10.1007/s11248-004-5415-6
Sardana, 2007, Biologically active human GM-CSF produced in the seeds of transgenic rice plants, Transgenic Res., 16, 713, 10.1007/s11248-006-9062-y
Zheng, 2006, Expression of bioactive human M-CSF soluble receptor in transgenic tobacco plants, Protein Expr. Purif., 46, 367, 10.1016/j.pep.2005.07.018
Hong, 2006, Production of bioactive human granulocyte-colony stimulating factor in transgenic rice cell suspension cultures, Protein Expr. Purif., 47, 68, 10.1016/j.pep.2005.09.028
Suo, 2006, Expression of active hBMP2 in transgenic tobacco plants, Plant Cell Rep., 25, 1316, 10.1007/s00299-006-0173-y