Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy in vitro

Sharman, 1999, Photodynamic therapeutics: Basic principles and clinical applications, Drug Discov Today, 4, 507, 10.1016/S1359-6446(99)01412-9

Agostinis, 2011, Photodynamic therapy of cancer: An update, CA Cancer J Clin, 61, 250, 10.3322/caac.20114

Moore, 1997, The biology of photodynamic therapy, Phys Med Biol, 42, 913, 10.1088/0031-9155/42/5/012

Wachowska, 2011, Aminolevulinic acid (ALA) as a prodrug in photodynamic therapy of cancer, Molecules, 16, 4140, 10.3390/molecules16054140

Ishizuka, 2011, Novel development of 5-aminolevurinic acid (ALA) in cancer diagnoses and therapy, Int Immunopharmacol, 11, 358, 10.1016/j.intimp.2010.11.029

Nokes, 2013, Aminolevulinic acid (ALA): Photodynamic detection and potential therapeutic applications, J Surg Res, 181, 262, 10.1016/j.jss.2013.02.002

Amo, 2009, Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937, Cell Biochem Funct, 27, 503, 10.1002/cbf.1603

Ji, 2010, 5-ALA mediated photodynamic therapy induces autophagic cell death via AMP-activated protein kinase, Mol Cancer Ther, 9, 91, 10.1186/1476-4598-9-91

Ben Sahra, 2010, Metformin in cancer therapy: A new perspective for an old antidiabetic drug?, Mol Cancer Ther, 9, 1092, 10.1158/1535-7163.MCT-09-1186

Del Barco, 2011, Metformin: Multi-faceted protection against cancer, Oncotarget, 2, 896, 10.18632/oncotarget.387

Dowling, 2007, Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells, Cancer Res, 67, 10804, 10.1158/0008-5472.CAN-07-2310

Ben Sahra, 2008, The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level, Oncogene, 27, 3576, 10.1038/sj.onc.1211024

Cantrell, 2010, Metformin is a potent inhibitor of endometrial cancer cell proliferation-implications for a novel treatment strategy, Gynecol Oncol, 116, 92, 10.1016/j.ygyno.2009.09.024

Dowling, 2011, Understanding the benefit of metformin use in cancer treatment, BMC Med, 9, 33, 10.1186/1741-7015-9-33

Rattan, 2011, Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo, Neoplasia, 13, 483, 10.1593/neo.11148

Rocha, 2011, Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth, Clin Cancer Res, 17, 3993, 10.1158/1078-0432.CCR-10-2243

Lin, 2013, Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription-3 activity independently of the liver kinase B1-AMP-activated protein kinase pathway, Am J Respir Cell Mol Biol, 49, 241, 10.1165/rcmb.2012-0244OC

Lin, 2014, Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress, Oncotarget, 5, 298, 10.18632/oncotarget.1628

Song, 2012, Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells, Sci Rep, 2, 362, 10.1038/srep00362