Human Dendritic Cell DC-SIGN and TLR-2 Mediate Complementary Immune Regulatory Activities in Response to Lactobacillus rhamnosus JB-1

PLoS ONE - Tập 10 Số 3 - Trang e0120261
Patrycja Konieczna1, Elisa Schiavi1, Mario Ziegler1, David Groeger2, Selena Healy2, Ray Grant3, Liam O’Mahony1
1Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
2Alimentary Health Ltd, Cork, Ireland
3Alimentary Health Pharma Davos, Davos, Switzerland

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YK Lee, 2010, Has the microbiota played a critical role in the evolution of the adaptive immune system?, Science, 330, 1768, 10.1126/science.1195568

F Shanahan, 2010, Gut microbes: from bugs to drugs, Am J Gastroenterol, 105, 275, 10.1038/ajg.2009.729

F Sommer, 2013, The gut microbiota—masters of host development and physiology, Nat Rev Microbiol, 11, 227, 10.1038/nrmicro2974

N Kamada, 2013, Control of pathogens and pathobionts by the gut microbiota, Nat Immunol, 14, 685, 10.1038/ni.2608

RD Pridmore, 2004, The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533, Proc Natl Acad Sci U S A, 101, 2512, 10.1073/pnas.0307327101

LW Peterson, 2014, Intestinal epithelial cells: regulators of barrier function and immune homeostasis, Nat Rev Immunol, 14, 141, 10.1038/nri3608

J Pluznick, 2013, A novel SCFA receptor, the microbiota, and blood pressure regulation, Gut Microbes, 5, 202, 10.4161/gmic.27492

R Frei, 2012, Microbiota and dietary interactions: an update to the hygiene hypothesis?, Allergy, 67, 451, 10.1111/j.1398-9995.2011.02783.x

JR Brestoff, 2013, Commensal bacteria at the interface of host metabolism and the immune system, Nat Immunol, 14, 676, 10.1038/ni.2640

S Sakaguchi, 2010, FOXP3+ regulatory T cells in the human immune system, Nat Rev Immunol, 10, 490, 10.1038/nri2785

M Akdis, 2004, Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells, J Exp Med, 199, 1567, 10.1084/jem.20032058

K Atarashi, 2011, Induction of colonic regulatory T cells by indigenous Clostridium species, Science, 331, 337, 10.1126/science.1198469

P van Baarlen, 2013, Regulation of intestinal homeostasis and immunity with probiotic lactobacilli, Trends Immunol, 34, 208, 10.1016/j.it.2013.01.005

MD Inman, 2009, Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice, Am J Respir Crit Care Med, 179, 186, 10.1164/rccm.200806-951OC

K Karimi, 2012, A Lactobacillus rhamnosus strain induces a heme oxygenase dependent increase in Foxp3+ regulatory T cells, PLoS One, 7, e47556, 10.1371/journal.pone.0047556

H Van der Kleij, 2008, Protective effects of Lactobacillus rhamnosus and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve, Am J Physiol Regul Integr Comp Physiol, 295, R1131, 10.1152/ajpregu.90434.2008

JA Bravo, 2011, Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve, Proc. Natl. Acad. Sci. USA, 108, 16050, 10.1073/pnas.1102999108

A Lyons, 2010, Bacterial strain-specific induction of Foxp3+ T regulatory cells is protective in murine allergy models, Clin Exp Allergy, 40, 811, 10.1111/j.1365-2222.2009.03437.x

Fernandez E Macho, 2011, Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2- mediated recognition of a specific peptidoglycan-derived muropeptide, Gut, 60, 1050, 10.1136/gut.2010.232918

C Grangette, 2005, Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids, Proc Natl Acad Sci U S A, 102, 10321, 10.1073/pnas.0504084102

MW Khan, 2012, Modulating intestinal immune responses by lipoteichoic acid-deficient Lactobacillus acidophilus, Immunotherapy, 4, 151, 10.2217/imt.11.163

F Yan, 2002, Probiotic bacterium prevents cytokine induced apoptosis in intestinal epithelial cells, J Biol Chem, 277, 50959, 10.1074/jbc.M207050200

F Yan, 2007, Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth, Gastroenterology, 132, 562, 10.1053/j.gastro.2006.11.022

F Yan, 2011, Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism, J Clin Invest, 121, 2242, 10.1172/JCI44031

M Meijerink, 2010, Identification of genetic loci in Lactobacillus plantarum that modulate the immune response of dendritic cells using comparative genome hybridization, PLoS One, 5, e10632, 10.1371/journal.pone.0010632

SR Konstantinov, 2008, S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions, Proc Natl Acad Sci U S A, 105, 19474, 10.1073/pnas.0810305105

R Frei, 2013, Histamine receptor 2 modifies dendritic cell responses to microbial ligands, J Allergy Clin Immunol, 132, 194, 10.1016/j.jaci.2013.01.013

R Ferstl, 2014, Histamine 2 receptor is a key influence in immune responses to intestinal histamine-secreting microbes, J Allergy Clin Immunol, 134, 744, 10.1016/j.jaci.2014.04.034

E Schiavi, 2015, Intestinal dendritic cells, Curr Opin Gastroenterol, 31, 98, 10.1097/MOG.0000000000000155

JL Round, 2011, The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota, Science, 332, 974, 10.1126/science.1206095

JL Round, 2010, Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota, Proc Natl Acad Sci U S A, 107, 12204, 10.1073/pnas.0909122107

S Manicassamy, 2009, Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity, Nat Med, 15, 401, 10.1038/nm.1925

J van Bergenhenegouwen, 2014, Extracellular vesicles modulate host-microbe responses by altering TLR2 activity and phagocytosis, PLoS One, 9, e89121, 10.1371/journal.pone.0089121

EA Koppel, 2005, Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation, Cell. Microbiol, 7, 157, 10.1111/j.1462-5822.2004.00480.x

P Konieczna, 2012, Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells, Gut, 61, 354, 10.1136/gutjnl-2011-300936

P Konieczna, 2012, Portrait of an immunoregulatory Bifidobacterium, Gut Microbes, 3, 261, 10.4161/gmic.20358

A Garg, 2008, Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection, Eur J Immunol, 38, 459, 10.1002/eji.200737268

HH Smits, 2005, Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin, J Allergy Clin Immunol, 115, 1260, 10.1016/j.jaci.2005.03.036

M Akdis, 2009, Therapeutic manipulation of immune tolerance in allergic disease, Nat Rev Drug Discov, 8, 645, 10.1038/nrd2653

L O'Mahony, 2010, Novel immunotherapeutic approaches for allergy and asthma, Autoimmunity, 43, 493, 10.3109/08916931003674725