New insights into the autotaxin/LPA axis in cancer development and metastasis

Experimental Cell Research - Tập 333 - Trang 183-189 - 2015
Raphaël Leblanc1, Olivier Peyruchaud1
1INSERM, UMR1033, UCB Lyon 1, Faculté de Médecine Lyon Est, Lyon, France

Tài liệu tham khảo

Merchant, 1991, Phospholipid profiles of human colon cancer using 31P magnetic resonance spectroscopy, Int. J. Colorectal Dis., 6, 121, 10.1007/BF00300208 Mills, 2003, The emerging role of lysophosphatidic acid in cancer, Nat. Rev. Cancer, 3, 582, 10.1038/nrc1143 Sasagawa, 1999, Abnormal serum lysophospholipids in multiple myeloma patients, Lipids, 34, 17, 10.1007/s11745-999-332-5 Baker, 2002, Plasma lysophosphatidic acid concentration and ovarian cancer, J. Am. Med. Assoc., 287, 3081, 10.1001/jama.287.23.3081 Eder, 2000, Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2, Clin. Cancer Res., 6, 2482 Furui, 1999, Overexpression of edg-2/vzg-1 induces apoptosis and anoikis in ovarian cancer cells in a lysophosphatidic acid-independent manner, Clin. Cancer Res., 5, 4308 Goetzl, 1999, Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer, Cancer Res., 59, 5370 Sutphen, 2004, Lysophospholipids are potential biomarkers of ovarian cancer, Cancer Epidemiol. Biomarkers Prev., 13, 1185, 10.1158/1055-9965.1185.13.7 Gerrard, 1989, Identification of the molecular species of lysophosphatidic acid produced when platelets are stimulated by thrombin, Biochim. Biophys. Acta, 1001, 282, 10.1016/0005-2760(89)90112-4 Eichholtz, 1993, The bioactive phospholipid lysophosphatidic acid is released from activated platelets, Biochem. J., 291, 677, 10.1042/bj2910677 Pustilnik, 1999, Lysophosphatidic acid induces urokinase secretion by ovarian cancer cells, Clin. Cancer Res., 5, 3704 Shida, 2003, Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1, Cancer Res., 63, 1706 Schulte, 2001, Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer, J. Int. Cancer, 92, 249, 10.1002/1097-0215(200102)9999:9999<::AID-IJC1166>3.0.CO;2-D Kitayama, 2004, Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma, Breast Cancer Res., 6, R640, 10.1186/bcr935 Shida, 2004, Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer, Lab. Invest., 84, 1352, 10.1038/labinvest.3700146 Shimomura, 2008, Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair, Nat. Genet., 40, 335, 10.1038/ng.100 Khan, 2011, Mutations in the LPAR6 and LIPH genes underlie autosomal recessive hypotrichosis/woolly hair in 17 consanguineous families from Pakistan, Clin. Exp. Dermatol., 36, 652, 10.1111/j.1365-2230.2011.04014.x Majewski, 2008, Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy, Lab. Invest., 88, 694, 10.1038/labinvest.2008.27 Lee, 2007, Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia, Proc. Natl. Acad. Sci. USA, 104, 13732, 10.1073/pnas.0701771104 Hama, 2004, Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1, J. Biol. Chem., 279, 17634, 10.1074/jbc.M313927200 Shida, 2004, Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells, Exp. Cell Res., 301, 168, 10.1016/j.yexcr.2004.08.008 Boucharaba, 2006, The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases, Proc. Natl. Acad. Sci. USA, 103, 9643, 10.1073/pnas.0600979103 David, 2012, Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis, Int. J. Oncol., 40, 1133, 10.3892/ijo.2011.1309 Yu, 2008, Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells, J. Natl. Cancer Inst., 100, 1630, 10.1093/jnci/djn378 Fishman, 2001, Lysophosphatidic acid promotes matrix metalloproteinase (MMP) activation and MMP-dependent invasion in ovarian cancer cells, Cancer Res., 61, 3194 Jeong, 2012, The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion, Oncogene, 31, 4279, 10.1038/onc.2011.595 Park, 2011, Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression, Oncogene, 30, 1351, 10.1038/onc.2010.517 Hope, 2009, LPA receptor 2 mediates LPA-induced endometrial cancer invasion, Gynecol. Oncol., 112, 215, 10.1016/j.ygyno.2008.09.019 Jongsma, 2011, LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor, PLoS One, 6, e29260, 10.1371/journal.pone.0029260 Lin, 2007, Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3, Biochem. Biophys. Res. Commun., 363, 1001, 10.1016/j.bbrc.2007.09.081 Ferrara, 2005, Angiogenesis as a therapeutic target, Nature, 438, 967, 10.1038/nature04483 Hu, 2001, Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells, J. Natl. Cancer Inst., 93, 762, 10.1093/jnci/93.10.762 Fujita, 2003, Expression of lysophosphatidic acid receptors and vascular endothelial growth factor mediating lysophosphatidic acid in the development of human ovarian cancer, Cancer Lett., 192, 161, 10.1016/S0304-3835(02)00713-9 Su, 2013, Autotaxin-lysophosphatidic acid signaling axis mediates tumorigenesis and development of acquired resistance to sunitinib in renal cell carcinoma, Clin. Cancer Res., 19, 6461, 10.1158/1078-0432.CCR-13-1284 Bachelier, 2014, Combination of anti-angiogenic therapies reduces osteolysis and tumor burden in experimental breast cancer bone metastasis, J. Int. Cancer, 135, 1319, 10.1002/ijc.28787 Boucharaba, 2009, Bioactive lipids lysophosphatidic acid and sphingosine 1-phosphate mediate breast cancer cell biological functions through distinct mechanisms, Oncol. Res., 18, 173, 10.3727/096504009790217399 Boucharaba, 2004, Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer, J. Clin. Invest., 114, 1714, 10.1172/JCI200422123 David, 2010, Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts, PLoS One, 5, e9741, 10.1371/journal.pone.0009741 Peyruchaud, 2013, Pleiotropic activity of lysophosphatidic acid in bone metastasis, Biochim. Biophys. Acta, 1831, 99, 10.1016/j.bbalip.2012.06.004 Gillet, 2010, Mechanisms of multidrug resistance in cancer, Methods Mol. Biol., 596, 47, 10.1007/978-1-60761-416-6_4 Fukui, 2012, Enhancement of drug resistance by lysophosphatidic acid receptor-3 in mouse mammary tumor FM3A cells, J. Toxicol. Pathol., 25, 225, 10.1293/tox.25.225 Kiss, 2013, Mitigation of radiation injury by selective stimulation of the LPA(2) receptor, Biochim. Biophys. Acta, 1831, 117, 10.1016/j.bbalip.2012.08.020 Stefan, 2005, NPP-type ectophosphodiesterases: unity in diversity, Trends Biochem. Sci., 30, 542, 10.1016/j.tibs.2005.08.005 Kawagoe, 1997, Expression and transcriptional regulation of the PD-Ialpha/autotaxin gene in neuroblastoma, Cancer Res., 57, 2516 Hoelzinger, 2005, Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets, Neoplasia, 7, 7, 10.1593/neo.04535 Zhang, 1999, Expression of autotaxin mRNA in human hepatocellular carcinoma, Chin. Med. J., 112, 330 Masuda, 2008, Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma, Br. J. Haematol., 143, 60, 10.1111/j.1365-2141.2008.07325.x Stracke, 1992, Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein, J. Biol. Chem., 267, 2524, 10.1016/S0021-9258(18)45911-X Stassar, 2001, Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization, Br. J. Cancer, 85, 1372, 10.1054/bjoc.2001.2074 Kehlen, 2004, Expression, regulation and function of autotaxin in thyroid carcinomas, J. Int. Cancer, 109, 833, 10.1002/ijc.20022 Yang, 2002, Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells, Clin. Exp. Metastasis, 19, 603, 10.1023/A:1020950420196 Yang, 1999, Autotaxin expression in non-small-cell lung cancer, Am. J. Respir. Cell Mol. Biol., 21, 216, 10.1165/ajrcmb.21.2.3667 Wu, 2010, Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma, Mol. Cancer, 9, 71, 10.1186/1476-4598-9-71 Black, 2004, Microarray analysis identifies Autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun, Oncogene, 23, 2357, 10.1038/sj.onc.1207377 Dufner-Beattie, 2001, Retinoic acid-induced expression of autotaxin in N-myc-amplified neuroblastoma cells, Mol. Carcinog., 30, 181, 10.1002/mc.1028 Chen, 2005, Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells, Oncogene, 24, 5125, 10.1038/sj.onc.1208729 Nam, 2000, Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells, Oncogene, 19, 241, 10.1038/sj.onc.1203263 Liu, 2009, Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases, Cancer Cell, 15, 539, 10.1016/j.ccr.2009.03.027 Benesch, 2014, Inhibition of autotaxin delays breast tumor growth and lung metastasis in mice, FASEB J., 28, 2655, 10.1096/fj.13-248641 Lu, 2006, A gene expression signature predicts survival of patients with stage I non-small cell lung cancer, PLoS Med., 3, e467, 10.1371/journal.pmed.0030467 Houben, 2011, Autotaxin and LPA receptor signaling in cancer, Cancer Metastasis Rev., 30, 557, 10.1007/s10555-011-9319-7 Nakai, 2011, Specific increase in serum autotaxin activity in patients with pancreatic cancer, Clin. Biochem., 44, 576, 10.1016/j.clinbiochem.2011.03.128 Jansen, 2009, Rapid clearance of the circulating metastatic factor autotaxin by the scavenger receptors of liver sinusoidal endothelial cells, Cancer Lett., 284, 216, 10.1016/j.canlet.2009.04.029 Watanabe, 2007, Both plasma lysophosphatidic acid and serum autotaxin levels are increased in chronic hepatitis C, J. Clin. Gastroenterol., 41, 616, 10.1097/01.mcg.0000225642.90898.0e Leblanc, 2014, Interaction of platelet-derived autotaxin with tumor integrin alphaVbeta3 controls metastasis of breast cancer cells to bone, Blood, 124, 3141, 10.1182/blood-2014-04-568683 Fulkerson, 2011, Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells, J. Biol. Chem., 286, 34654, 10.1074/jbc.M111.276725 Wu, 2014, Integrin-mediated cell surface recruitment of autotaxin promotes persistent directional cell migration, FASEB J., 28, 861, 10.1096/fj.13-232868 David, 2014, Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers, PLoS One, 9, e97771, 10.1371/journal.pone.0097771