Liver chimeric mice with tupaia hepatocyte transplantation as an animal model for hepatitis B virus infection and antiviral therapy

Trepo, 2014, Hepatitis B virus infection, Lancet, 384, 2053, 10.1016/S0140-6736(14)60220-8 Liu, 2007, Hepatitis B in China, Lancet, 369, 1582, 10.1016/S0140-6736(07)60723-5 Lai, 2003, T. Viral hepatitis B, Lancet, 362, 2089, 10.1016/S0140-6736(03)15108-2 Durantel, 2016, New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus, Journal of hepatology, 64, S117, 10.1016/j.jhep.2016.02.016 Allweiss, 2016, Experimental in vitro and in vivo models for the study of human hepatitis B virus infection, J. Hepatol., 64, S17, 10.1016/j.jhep.2016.02.012 Thomas, 2016, Experimental models of hepatitis B and C - new insights and progress, Nat. Rev. Gastroenterol. Hepatol., 13, 362, 10.1038/nrgastro.2016.37 Walter, 1996, Hepatitis B virus infection of tupaia hepatocytes in vitro and in vivo, Hepatology, 24, 1 Dandri, 2005, Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes, J. Hepatol., 42, 54, 10.1016/j.jhep.2004.09.021 Sanada, 2016, Property of hepatitis B virus replication in Tupaia belangeri hepatocytes, Biochemical and biophysical research communications, 469, 229, 10.1016/j.bbrc.2015.11.121 Liu, 2018, Bioinspired Artificial Nanodecoys for Hepatitis B Virus, Angew Chem Int Ed Engl., 57, 12499, 10.1002/anie.201807212 Yuan, 2018, A chimeric humanized mouse model by engrafting the human induced pluripotent stem cell-derived hepatocyte-like cell for the chronic hepatitis B virus infection, Front. Microbiol., 9 Yuan, 2018, Optimized HepaRG is a suitable cell source to generate the human liver chimeric mouse model for the chronic hepatitis B virus infection, Emerg. Microbes Infect., 7, 144, 10.1038/s41426-018-0143-9 Yuan, 2019, HBV infection-induced liver cirrhosis development in dual-humanised mice with human bone mesenchymal stem cell transplantation, Gut., 68, 2044, 10.1136/gutjnl-2018-316091 Yuan, 2019, Agonist c-met monoclonal antibody augments the proliferation of hiPSC-derived hepatocyte-like cells and improves cell transplantation therapy for liver failure in mice, Theranostics, 9, 2115, 10.7150/thno.30009 Liu, 2016, Detection and analysis of tupaia hepatocytes via mAbs against tupaia serum albumin, Exp. Anim., 65, 117, 10.1538/expanim.15-0086 Kock, 2001, Efficient infection of primary tupaia hepatocytes with purified human and woolly monkey hepatitis B virus, J. Virol., 75, 5084, 10.1128/JVI.75.11.5084-5089.2001 Zhao, 2002, Primary hepatocytes of Tupaia belangeri as a potential model for hepatitis C virus infection, J. Clin. Invest, 109, 221, 10.1172/JCI0213011 Tong, 2016, Overview of hepatitis B viral replication and genetic variability, J. Hepatol., 64, S4, 10.1016/j.jhep.2016.01.027 Eren, 2000, Preclinical evaluation of two human anti-hepatitis B virus (HBV) monoclonal antibodies in the HBV-trimera mouse model and in HBV chronic carrier chimpanzees, Hepatology, 32, 588, 10.1053/jhep.2000.9632 Neumann, 2010, Novel mechanism of antibodies to hepatitis B virus in blocking viral particle release from cells, Hepatology, 52, 875, 10.1002/hep.23778 Jaoude, 2005, Role of the antigenic loop of the hepatitis B virus envelope proteins in infectivity of hepatitis delta virus, J. Virol., 79, 10460, 10.1128/JVI.79.16.10460-10466.2005 Zhang, 2016, Prolonged suppression of HBV inmice by a novel antibody that targets a unique epitope on hepatitis B surface antigen, Gut., 65, 658, 10.1136/gutjnl-2014-308964