Simvastatin (MK-733): a potent cholesterol synthesis inhibitor in heterozygous familial hypercholesterolaemia
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Slack, 1969, Risks of ischaemic heart disease in familial hyperlipoproteinaemia states, Lancet, ii, 1380, 10.1016/S0140-6736(69)90930-1
Goldstein, 1983, Familial hypercholesterolemia, 672
Mabuchi, 1981, Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase on serum lipoproteins and ubiquinone-10 levels in patients with familial hypercholesterolemia, N. Engl. J. Med., 305, 478, 10.1056/NEJM198108273050902
Illingworth, 1984, Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia, J. Clin. Invest., 74, 1972, 10.1172/JCI111618
Hoeg, 1986, Effectiveness of mevinolin on plasma lipoprotein concentrations in type II hyperlipoproteinemia, Am. J. Cardiol., 57, 933, 10.1016/0002-9149(86)90733-2
1986, Therapeutic response to lovastatin (mevinolin) in non familial hypercholesterolemia. A multicenter study, J. Am. Med. Assoc., 256, 2829, 10.1001/jama.256.20.2829
Mabuchi, 1983, Reduction of serum cholesterol in heterozygous patients with familial hypercholesterolemia. Additive effects of compactin and cholestyramine, N. Engl. J. Med., 308, 609, 10.1056/NEJM198303173081101
Illingworth, 1984, Mevinolin plus colestipol in therapy for severe heterozygous familial hypercholesterolemia, Ann. Intern. Med., 101, 598, 10.7326/0003-4819-101-5-598
Grundy, 1985, Influence of combined therapy with mevinolin and interruption of bile-acid reabsorption on low density lipoproteins in heterozygous familial hypercholesterolemia, Ann. Intern. Med., 103, 339, 10.7326/0003-4819-103-3-339
Mol, 1986, Effects of synvinolin (MK-733) on plasma lipids in familial hypercholesterolaemia, Lancet, ii, 936, 10.1016/S0140-6736(86)90598-2
Röschlau, 1974, Enzymatische Bestimmung des Gesamtcholesterins im Serum, J. Clin. Chem. Clin. Biochem., 12, 403
Demacker, 1975, An improved semi-automatic method for the colorimetric determination of triglycerides in serum, Clin. Chim. Acta, 64, 45, 10.1016/0009-8981(75)90142-4
Giegel, 1975, Manual and semi-automated procedures for measurement of triglycerides in serum, Clin. Chem., 21, 1575, 10.1093/clinchem/21.11.1575
Lopez-Virella, 1977, Cholesterol determination in high density lipoproteins separated by three different methods, Clin. Chem., 23, 882, 10.1093/clinchem/23.5.882
Demacker, 1980, A study of the use of polyethylene glycol in estimating cholesterol in high density lipoprotein, Clin. Chem., 26, 1775, 10.1093/clinchem/26.13.1775
Friedewald, 1972, Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge, Clin. Chem., 18, 499, 10.1093/clinchem/18.6.499
Stuyt, 1985, A comparative study on the effects of acipimox and clofibrate in type III ad type IV hyperlipoproteinemia, Atherosclerosis, 55, 51, 10.1016/0021-9150(85)90165-0
Tobert, 1982, Cholesterol-lowering effect of mevinolin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase in healthy volunteers, J. Clin. Invest., 69, 913, 10.1172/JCI110530
Brown, 1980, Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth, J. Lipid Res., 21, 505, 10.1016/S0022-2275(20)42221-7
Kovanen, 1981, Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog, 78, 1194
Bilheimer, 1983, Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes, 80, 4124
Grundy, 1985, Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia, J. Lipid Res., 26, 1464, 10.1016/S0022-2275(20)34252-8