The sentinel node approach in gynaecological malignancies

Clinical and Translational Imaging - Tập 4 - Trang 411-420 - 2016
Angela Collarino1,2, Sergi Vidal-Sicart3, Germano Perotti1, Renato A. Valdés Olmos2,4,5
1Institute of Nuclear Medicine, Università Cattolica del Sacro Cuore, Rome, Italy
2Nuclear Medicine Section, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
3Department of Nuclear Medicine, University Hospital Clínic Barcelona, Barcelona, Spain
4Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands
5Department of Nuclear Medicine, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

Tóm tắt

This review discusses the state-of-the-art of sentinel lymph node mapping in gynaecological malignancies, including cervical cancer, endometrial cancer, and vulvar cancer, with an emphasis on new technological advances. For this objective, PubMed/MEDLINE was searched for relevant studies about the sentinel lymph node procedure in gynaecology. In particular, the use of preoperative lymphatic mapping with lymphoscintigraphy and single photon emission tomography/computed tomography (SPECT/CT) was identified in 18 studies. Other recent advances as hybrid tracers (e.g. ICG-99mTc-nanocolloid) and intraoperative tools (portable γ-camera and 3D navigation devices) appear to also represent a useful guide for the surgeon during the operation. Concerning vulvar and cervical cancers, the sentinel lymph node procedure has been incorporated to the current guidelines in Europe and North America, whereas for endometrial cancer it is considered investigative.

Tài liệu tham khảo

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