Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle

Neuron - Tập 81 - Trang 49-60 - 2014
Jens Niewoehner1, Bernd Bohrmann2, Ludovic Collin2, Eduard Urich2, Hadassah Sade1, Peter Maier1, Petra Rueger1, Jan Olaf Stracke1, Wilma Lau1, Alain C. Tissot1, Hansruedi Loetscher2, Anirvan Ghosh2, Per-Ola Freskgård2
1Pharma Research and Early Development, Large Molecule Research, F. Hoffmann-La Roche, Penzberg 82377, Germany
2Pharma Research and Early Development, Neuroscience Discovery and Translation Area, F. Hoffmann-La Roche, Basel 4070, Switzerland

Tài liệu tham khảo

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