Activation of Oas1a gene expression by type I IFN requires both STAT1 and STAT2 while only STAT2 is required for Oas1b activation

Andersen, 2008, IRF-3-dependent and augmented target genes during viral infection, Genes Immun., 9, 168, 10.1038/sj.gene.6364449 Barnes, 2004, Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection, J. Biol. Chem., 279, 45194, 10.1074/jbc.M400726200 Basagoudanavar, 2011, Distinct roles for the NF-kappa B RelA subunit during antiviral innate immune responses, J. Virol., 85, 2599, 10.1128/JVI.02213-10 Bluyssen, 1997, Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA, J. Biol. Chem., 272, 4600, 10.1074/jbc.272.7.4600 Bluyssen, 1995, Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses, Proc. Natl. Acad. Sci. U. S. A., 92, 5645, 10.1073/pnas.92.12.5645 Bonnevie-Nielsen, 2005, Variation in antiviral 2′,5′-oligoadenylate synthetase (2′5′AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene, Am. J. Hum. Genet., 76, 623, 10.1086/429391 Brandes, 1996, Novel features of drosophila period transcription revealed by real-time luciferase reporting, Neuron, 16, 687, 10.1016/S0896-6273(00)80088-4 Chang, 2006, Flavivirus induces interferon-beta gene expression through a pathway involving RIG-I-dependent IRF-3 and PI3K-dependent NF-kappaB activation, Microbes Infect., 8, 157, 10.1016/j.micinf.2005.06.014 Chen, 2006, Promoter analysis of interleukin 19, Biochem. Biophys. Res. Commun., 344, 713, 10.1016/j.bbrc.2006.03.200 Currie, 1998, NF-Y is associated with the histone acetyltransferases GCN5 and P/CAF, J. Biol. Chem., 273, 1430, 10.1074/jbc.273.3.1430 Darnell, 1997, STATs and gene regulation, Science, 277, 1630, 10.1126/science.277.5332.1630 Darnell, 1994, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science, 264, 1415, 10.1126/science.8197455 Decker, 1997, GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression, J. Interferon Cytokine Res., 17, 121, 10.1089/jir.1997.17.121 Diamond, 2009, Mechanisms of evasion of the type I interferon antiviral response by flaviviruses, J. Interferon Cytokine Res., 29, 521, 10.1089/jir.2009.0069 Dolfini, 2009, A perspective of promoter architecture from the CCAAT box, Cell Cycle, 8, 4127, 10.4161/cc.8.24.10240 Ehret, 2001, DNA binding specificity of different STAT proteins. Comparison of in vitro specificity with natural target sites, J. Biol. Chem., 276, 6675, 10.1074/jbc.M001748200 Elbahesh, 2011, The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2–5A synthesis in intact cells, Virology, 409, 262, 10.1016/j.virol.2010.10.016 Elco, 2005, Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3, J. Virol., 79, 3920, 10.1128/JVI.79.7.3920-3929.2005 Eskildsen, 2002, Gene structure of the murine 2′–5′-oligoadenylate synthetase family, Cell. Mol. Life Sci., 59, 1212, 10.1007/s00018-002-8499-2 Eskildsen, 2003, Characterization of the 2′–5′-oligoadenylate synthetase ubiquitin-like family, Nucleic Acids Res., 31, 3166, 10.1093/nar/gkg427 Floyd-Smith, 1999, Transcriptional induction of the p69 isoform of 2′,5′-oligoadenylate synthetase by interferon-beta and interferon-gamma involves three regulatory elements and interferon-stimulated gene factor 3, Exp. Cell Res., 246, 138, 10.1006/excr.1998.4296 Garban, 2001, Nitric oxide inhibits the transcription repressor Yin-Yang 1 binding activity at the silencer region of the Fas promoter: a pivotal role for nitric oxide in the up-regulation of Fas gene expression in human tumor cells, J. Immunol., 167, 75, 10.4049/jimmunol.167.1.75 George, 2008, Organization of the mouse RNA-specific adenosine deaminase Adar1 gene 5′-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon, Virology, 380, 338, 10.1016/j.virol.2008.07.029 Grandvaux, 2002, Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes, J. Virol., 76, 5532, 10.1128/JVI.76.11.5532-5539.2002 Grilli, 1993, NF-kappa B and Rel: participants in a multiform transcriptional regulatory system, Int. Rev. Cytol., 143, 1, 10.1016/S0074-7696(08)61873-2 Guo, 2005, A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene, J. Immunol., 175, 7407, 10.4049/jimmunol.175.11.7407 Hahm, 2005, Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling, Immunity, 22, 247, 10.1016/j.immuni.2005.01.005 Hartmann, 1998, p59OASL, a 2′–5′ oligoadenylate synthetase like protein: a novel human gene related to the 2′–5′ oligoadenylate synthetase family, Nucleic Acids Res., 26, 4121, 10.1093/nar/26.18.4121 Higai, 2008, Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells, Glycoconj. J., 25, 225, 10.1007/s10719-008-9114-z Hovnanian, 1998, The human 2′,5′-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40-kDa forms, Genomics, 52, 267, 10.1006/geno.1998.5443 Hovnanian, 1999, The human 2′,5′-oligoadenylate synthetase-like gene (OASL) encoding the interferon-induced 56-kDa protein maps to chromosome 12q24.2 in the proximity of the 2′,5′-OAS locus, Genomics, 56, 362, 10.1006/geno.1998.5737 Jackson, 1998, Synergistic activation of transcription by nuclear factor Y and sterol regulatory element binding protein, J. Lipid Res., 39, 767, 10.1016/S0022-2275(20)32565-7 Jin, 1998, Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y, Mol. Cell. Biol., 18, 4377, 10.1128/MCB.18.7.4377 Justesen, 2000, Gene structure and function of the 2′–5′-oligoadenylate synthetase family, Cell. Mol. Life Sci.., 57, 1593, 10.1007/PL00000644 Kabe, 2005, NF-Y is essential for the recruitment of RNA polymerase II and inducible transcription of several CCAAT box-containing genes, Mol. Cell. Biol., 25, 512, 10.1128/MCB.25.1.512-522.2005 Kakuta, 2002, Genomic structure of the mouse 2′,5′-oligoadenylate synthetase gene family, J. Interferon Cytokine Res., 22, 981, 10.1089/10799900260286696 Kaur, 2005, The PI3′ kinase pathway in interferon signaling, J. Interferon Cytokine Res., 25, 780, 10.1089/jir.2005.25.780 Kowenz-Leutz, 1999, A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes, Mol. Cell, 4, 735, 10.1016/S1097-2765(00)80384-6 Kraus, 2003, A hybrid IRF9-STAT2 protein recapitulates interferon-stimulated gene expression and antiviral response, J. Biol. Chem., 278, 13033, 10.1074/jbc.M212972200 Li, 1998, Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo, EMBO J., 17, 6300, 10.1093/emboj/17.21.6300 Lindas, 2007, Characterization of the promoter of the gene encoding human tripeptidyl-peptidase II and identification of upstream silencer elements, Gene, 393, 62, 10.1016/j.gene.2007.01.015 Lou, 2009, IRF-9/STAT2 functional interaction drives retinoic acid-induced gene G expression independently of STAT1, Cancer Res., 69, 3673, 10.1158/0008-5472.CAN-08-4922 Mantovani, 1999, The molecular biology of the CCAAT-binding factor NF-Y, Gene, 239, 15, 10.1016/S0378-1119(99)00368-6 Mashimo, 2003, Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2′,5′-oligoadenylate synthetases, Genomics, 82, 537, 10.1016/S0888-7543(03)00176-9 Merika, 2001, Enhanceosomes, Curr. Opin. Genet. Dev., 11, 205, 10.1016/S0959-437X(00)00180-5 Nakaya, 2001, Gene induction pathways mediated by distinct IRFs during viral infection, Biochem. Biophys. Res. Commun., 283, 1150, 10.1006/bbrc.2001.4913 Ousman, 2005, Differential regulation of interferon regulatory factor (IRF)-7 and IRF-9 gene expression in the central nervous system during viral infection, J. Virol., 79, 7514, 10.1128/JVI.79.12.7514-7527.2005 Perelygin, 2002, Positional cloning of the murine flavivirus resistance gene, Proc. Natl. Acad. Sci. U. S. A., 99, 9322, 10.1073/pnas.142287799 Perelygin, 2006, The mammalian 2′–5′ oligoadenylate synthetase gene family: evidence for concerted evolution of paralogous Oas1 genes in Rodentia and Artiodactyla, J. Mol. Evol., 63, 562, 10.1007/s00239-006-0073-3 Perry, 2011, STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor, PLoS Pathog., 7, e1001297, 10.1371/journal.ppat.1001297 Peters, 2002, IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA, Proc. Natl. Acad. Sci. U. S. A., 99, 6322, 10.1073/pnas.092133199 Qureshi, 1995, Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3, Proc. Natl. Acad. Sci. U. S. A., 92, 3829, 10.1073/pnas.92.9.3829 Randall, 2008, Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures, J. Gen. Virol., 89, 1, 10.1099/vir.0.83391-0 Rebouillat, 1998, Molecular cloning and characterization of two related and interferon-induced 56-kDa and 30-kDa proteins highly similar to 2′–5′ oligoadenylate synthetase, Eur. J. Biochem., 257, 319, 10.1046/j.1432-1327.1998.2570319.x Rebouillat, 2000, Characterization of the gene encoding the 100-kDa form of human 2′,5′ oligoadenylate synthetase, Genomics, 70, 232, 10.1006/geno.2000.6382 Reith, 1994, Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y, Proc. Natl. Acad. Sci. U. S. A., 91, 554, 10.1073/pnas.91.2.554 Rutherford, 1991, The murine 2–5A synthetase locus: three distinct transcripts from two linked genes, Nucleic Acids Res., 19, 1917, 10.1093/nar/19.8.1917 Salsi, 2003, Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function, J. Biol. Chem., 278, 6642, 10.1074/jbc.M210065200 Samuel, 2001, Antiviral actions of interferons, Clin. Microbiol. Rev., 14, 778, 10.1128/CMR.14.4.778-809.2001 Sarkis, 2006, STAT1-independent cell type-specific regulation of antiviral APOBEC3G by IFN-alpha, J. Immunol., 177, 4530, 10.4049/jimmunol.177.7.4530 Scherbik, 2006, RNase L plays a role in the antiviral response to West Nile virus, J. Virol., 80, 2987, 10.1128/JVI.80.6.2987-2999.2006 Scherbik, 2007, Differential expression of interferon (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts, J. Virol., 81, 12005, 10.1128/JVI.01359-07 Shibata, 2001, Cloning of a novel 2′,5′-oligoadenylate synthetase-like molecule, Oasl5 in mice, Gene, 271, 261, 10.1016/S0378-1119(01)00508-X Smale, 1997, Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes, Biochim. Biophys. Acta, 1351, 73, 10.1016/S0167-4781(96)00206-0 Smale, 1989, The “initiator” as a transcription control element, Cell, 57, 103, 10.1016/0092-8674(89)90176-1 Stark, 1998, How cells respond to interferons, Annu. Rev. Biochem., 67, 227, 10.1146/annurev.biochem.67.1.227 Su, 2007, Central role of interferon regulatory factor-1 (IRF-1) in controlling retinoic acid inducible gene-I (RIG-I) expression, J. Cell. Physiol., 213, 502, 10.1002/jcp.21128 Takaoka, 2006, Interferon signalling network in innate defence, Cell. Microbiol., 8, 907, 10.1111/j.1462-5822.2006.00716.x Taniguchi, 2001, A weak signal for strong responses: interferon-alpha/beta revisited, Nat. Rev. Mol. Cell Biol., 2, 378, 10.1038/35073080 Tenoever, 2007, Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity, Science, 315, 1274, 10.1126/science.1136567 Thompson, 1991, Modulation of firefly luciferase stability and impact on studies of gene regulation, Gene, 103, 171, 10.1016/0378-1119(91)90270-L Wang, 1997, The p69/71 2–5A synthetase promoter contains multiple regulatory elements required for interferon-alpha-induced expression, DNA Cell Biol., 16, 1385, 10.1089/dna.1997.16.1385 Wright, 1995, Major histocompatibility complex class II-associated invariant chain gene expression is up-regulated by cooperative interactions of Sp1 and NF-Y, J. Biol. Chem., 270, 20978, 10.1074/jbc.270.36.20978 Yan, 2005, Mice deficient in oocyte-specific oligoadenylate synthetase-like protein OAS1D display reduced fertility, Mol. Cell. Biol., 25, 4615, 10.1128/MCB.25.11.4615-4624.2005 Yu, 1999, Transcriptional induction of p69 2′–5′-oligoadenylate synthetase by interferon-alpha is stimulated by 12-O-tetradecanoyl phorbol-13-acetate through IRF/ISRE binding motifs, Gene, 237, 177, 10.1016/S0378-1119(99)00284-X