Cell Signaling by Receptor Tyrosine Kinases
Tài liệu tham khảo
Amit, 2007, A module of negative feedback regulators defines growth factor signaling, Nat. Genet., 39, 503, 10.1038/ng1987
Bae, 2009, The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site, Cell, 138, 514, 10.1016/j.cell.2009.05.028
Bae, 1997, Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation, J. Biol. Chem., 272, 217, 10.1074/jbc.272.1.217
Barton, 2006, Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex, Nat. Struct. Mol. Biol., 13, 524, 10.1038/nsmb1101
Bean, 2008, Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma, Clin. Cancer Res., 14, 7519, 10.1158/1078-0432.CCR-08-0151
Bianco, 2008, Vascular endothelial growth factor receptor-1 contributes to resistance to anti-epidermal growth factor receptor drugs in human cancer cells, Clin. Cancer Res., 14, 5069, 10.1158/1078-0432.CCR-07-4905
Blume-Jensen, 2001, Oncogenic kinase signalling, Nature, 411, 355, 10.1038/35077225
Bouyain, 2005, The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand, Proc. Natl. Acad. Sci. USA, 102, 15024, 10.1073/pnas.0507591102
Buday, 1995, Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos, Oncogene, 11, 1327
Burgess, 2003, An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors, Mol. Cell, 12, 541, 10.1016/S1097-2765(03)00350-2
Chen, 2007, A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases, Mol. Cell, 27, 717, 10.1016/j.molcel.2007.06.028
Chen, 2008, Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases, Proc. Natl. Acad. Sci. USA, 105, 18267, 10.1073/pnas.0807762105
Chen, 2005, A novel endocytic recycling signal distinguishes biological responses of Trk neurotrophin receptors, Mol. Biol. Cell, 16, 5761, 10.1091/mbc.E05-07-0651
Cho, 2002, Structure of the extracellular region of HER3 reveals an interdomain tether, Science, 297, 1330, 10.1126/science.1074611
Choudhary, 2009, Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes, Mol. Cell, 36, 326, 10.1016/j.molcel.2009.09.019
Chow, 2007, Sunitinib: from rational design to clinical efficacy, J. Clin. Oncol., 25, 884, 10.1200/JCO.2006.06.3602
Citri, 2006, EGF-ERBB signalling: towards the systems level, Nat. Rev. Mol. Cell Biol., 7, 505, 10.1038/nrm1962
Clayton, 2005, Ligand-induced dimer-tetramer transition during the activation of the cell surface epidermal growth factor receptor-A multidimensional microscopy analysis, J. Biol. Chem., 280, 30392, 10.1074/jbc.M504770200
Cobb, 1989, Autophosphorylation activates the soluble cytoplasmic domain of the insulin receptor in an intermolecular reaction, J. Biol. Chem., 264, 18701, 10.1016/S0021-9258(18)51524-6
Corless, 2008, Molecular pathobiology of gastrointestinal stromal sarcomas, Annu. Rev. Pathol., 3, 557, 10.1146/annurev.pathmechdis.3.121806.151538
Di Guglielmo, 1994, Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma, EMBO J., 13, 4269, 10.1002/j.1460-2075.1994.tb06747.x
Dibb, 2004, Switching on kinases: oncogenic activation of BRAF and the PDGFR family, Nat. Rev. Cancer, 4, 718, 10.1038/nrc1434
Doolittle, 1983, Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor, Science, 221, 275, 10.1126/science.6304883
Downward, 1984, Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences, Nature, 307, 521, 10.1038/307521a0
Eck, 1996, Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2, Nature, 379, 277, 10.1038/379277a0
Engelman, 2009, Targeting PI3K signalling in cancer: opportunities, challenges and limitations, Nat. Rev. Cancer, 9, 550, 10.1038/nrc2664
Engelman, 2008, Acquired resistance to tyrosine kinase inhibitors during cancer therapy, Curr. Opin. Genet. Dev., 18, 73, 10.1016/j.gde.2008.01.004
Engelman, 2007, MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling, Science, 316, 1039, 10.1126/science.1141478
Eswarakumar, 2005, Cellular signaling by fibroblast growth factor receptors, Cytokine Growth Factor Rev., 16, 139, 10.1016/j.cytogfr.2005.01.001
Favelyukis, 2001, Structure and autoregulation of the insulin-like growth factor 1 receptor kinase, Nat. Struct. Mol. Biol., 8, 1058, 10.1038/nsb721
Ferguson, 2003, EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization, Mol. Cell, 11, 507, 10.1016/S1097-2765(03)00047-9
Forbes, 2010, COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer, Nucleic Acids Res., 38, D652, 10.1093/nar/gkp995
Furdui, 2006, Autophosphorylation of FGFR1 kinase is mediated by a sequential and precisely ordered reaction, Mol. Cell, 21, 711, 10.1016/j.molcel.2006.01.022
Gadella, 1995, Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation, J. Cell Biol., 129, 1543, 10.1083/jcb.129.6.1543
Garrett, 2002, Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha, Cell, 110, 763, 10.1016/S0092-8674(02)00940-6
Griffith, 2004, The structural basis for autoinhibition of FLT3 by the juxtamembrane domain, Mol. Cell, 13, 169, 10.1016/S1097-2765(03)00505-7
Gu, 2003, The “Gab” in signal transduction, Trends Cell Biol., 13, 122, 10.1016/S0962-8924(03)00002-3
Gual, 2001, Gab1 phosphorylation: a novel mechanism for negative regulation of HGF receptor signaling, Oncogene, 20, 156, 10.1038/sj.onc.1204047
Himanen, 2003, Eph signaling: a structural view, Trends Neurosci., 26, 46, 10.1016/S0166-2236(02)00005-X
Honegger, 1989, Evidence that autophosphorylation of solubilized receptors for epidermal growth factor is mediated by intermolecular cross-phosphorylation, Proc. Natl. Acad. Sci. USA, 86, 925, 10.1073/pnas.86.3.925
Huang, 2006, Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain, Mol. Cell, 21, 737, 10.1016/j.molcel.2006.02.018
Huang, 2007, EGF receptor ubiquitination is not necessary for its internalization, Proc. Natl. Acad. Sci. USA, 104, 16904, 10.1073/pnas.0707416104
Huang, 2008, Phosphoproteomics: Unraveling the signaling web, Mol. Cell, 31, 777, 10.1016/j.molcel.2008.09.001
Hubbard, 2004, Juxtamembrane autoinhibition in receptor tyrosine kinases, Nat. Rev. Mol. Cell Biol., 5, 464, 10.1038/nrm1399
Hunter, 2007, The age of crosstalk: Phosphorylation, ubiquitination, and beyond, Mol. Cell, 28, 730, 10.1016/j.molcel.2007.11.019
Hurley, 2006, Ubiquitin-binding domains, Biochem. J., 399, 361, 10.1042/BJ20061138
Huse, 2002, The conformational plasticity of protein kinases, Cell, 109, 275, 10.1016/S0092-8674(02)00741-9
Hynes, 2006, Targeting ADAMS and ERBBs in lung cancer, Cancer Cell, 10, 7, 10.1016/j.ccr.2006.06.012
Ibrahimi, 2005, Analysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerization, Mol. Cell. Biol., 25, 671, 10.1128/MCB.25.2.671-684.2005
Jones, 2006, A quantitative protein interaction network for the ErbB receptors using protein microarrays, Nature, 439, 168, 10.1038/nature04177
Jura, 2009, Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment, Cell, 137, 1293, 10.1016/j.cell.2009.04.025
Kao, 2001, Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells, J. Biol. Chem., 276, 18169, 10.1074/jbc.M008870200
Kermorgant, 2008, Receptor trafficking controls weak signal delivery: a stratedy employed by c-Met for STAT3 nuclear accumulation, J. Cell Biol., 182, 855, 10.1083/jcb.200806076
Kholodenko, 2006, Cell-signalling dynamics in time and space, Nat. Rev. Mol. Cell Biol., 7, 165, 10.1038/nrm1838
Kim, 2008, Lrp4 is a receptor for agrin and forms a complex with MuSK, Cell, 135, 334, 10.1016/j.cell.2008.10.002
Kirkin, 2007, Role of ubiquitin- and Ubl-binding proteins in cell signaling, Curr. Opin. Cell Biol., 19, 199, 10.1016/j.ceb.2007.02.002
Kitano, 2004, Biological robustness, Nat. Rev. Genet., 5, 826, 10.1038/nrg1471
Knowles, 2006, Structure and chemical inhibition of the RET tyrosine kinase domain, J. Biol. Chem., 281, 33577, 10.1074/jbc.M605604200
Ladbury, 2000, Searching for specificity in SH domains, Chem. Biol., 7, R3, 10.1016/S1074-5521(00)00067-3
Lax, 2002, The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors, Mol. Cell, 10, 709, 10.1016/S1097-2765(02)00689-5
Lazzara, 2009, Quantitative modeling perspectives on the ErbB system of cell regulatory processes, Exp. Cell Res., 315, 717, 10.1016/j.yexcr.2008.10.033
Lee, 2006, Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain, PLoS Med., 3, e485, 10.1371/journal.pmed.0030485
Leppänen, 2010, Structural determinants of growth factor binding and specificity by VEGF receptor 2, Proc. Natl. Acad. Sci. USA, 107, 2425, 10.1073/pnas.0914318107
Li, 2005, Specificity and versatility of SH3 and other proline-recognition domains: structural basis and implications for cellular signal transduction, Biochem. J., 390, 641, 10.1042/BJ20050411
Li, 2008, ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling, Cell. Signal., 20, 2145, 10.1016/j.cellsig.2008.08.006
Libermann, 1985, Amplification, enhanced expression and possible rearrangment of EGF receptor gene in primary human brain tumours of glial origin, Nature, 313, 144, 10.1038/313144a0
Liu, 2007, Structural basis for stem cell factor-KIT signaling and activation of class III receptor tyrosine kinases, EMBO J., 26, 891, 10.1038/sj.emboj.7601545
Lynch, 2004, Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib, N. Engl. J. Med., 350, 2129, 10.1056/NEJMoa040938
Macdonald-Obermann, 2009, The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding, J. Biol. Chem., 284, 13570, 10.1074/jbc.M109.001487
Marshall, 1995, Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation, Cell, 80, 179, 10.1016/0092-8674(95)90401-8
Miaczynska, 2004, Not just a sink: endosomes in control of signal transduction, Curr. Opin. Cell Biol., 16, 400, 10.1016/j.ceb.2004.06.005
Mohammadi, 1996, Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism, Cell, 86, 577, 10.1016/S0092-8674(00)80131-2
Mol, 2004, Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase, J. Biol. Chem., 279, 31655, 10.1074/jbc.M403319200
Mosesson, 2003, Endocytosis of receptor tyrosine kinases is driven by monoubiquitylation, not polyubiquitylation, J. Biol. Chem., 278, 21323, 10.1074/jbc.C300096200
Mothe, 1996, Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action, J. Biol. Chem., 271, 11222, 10.1074/jbc.271.19.11222
Murphy, 2006, MAPK signal specificity: the right place at the right time, Trends Biochem. Sci., 31, 268, 10.1016/j.tibs.2006.03.009
Niu, 2002, Deletion of the carboxyl terminus of Tie2 enhances kinase activity, signaling, and function. Evidence for an autoinhibitory mechanism, J. Biol. Chem., 277, 31768, 10.1074/jbc.M203995200
Nolen, 2004, Regulation of protein kinases; controlling activity through activation segment conformation, Mol. Cell, 15, 661, 10.1016/j.molcel.2004.08.024
Noselli, 2000, Signal transduction. Are there close encounters between signaling pathways?, Science, 290, 68, 10.1126/science.290.5489.68
Oda, 2005, A comprehensive pathway map of epidermal growth factor receptor signaling, Mol. Syst. Biol., 1, 10.1038/msb4100014
Ogiso, 2002, Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains, Cell, 110, 775, 10.1016/S0092-8674(02)00963-7
Ostman, 2001, Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases, Trends Cell Biol., 11, 258, 10.1016/S0962-8924(01)01990-0
Pawson, 1995, Protein modules and signalling networks, Nature, 373, 573, 10.1038/373573a0
Pawson, 2004, Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems, Cell, 116, 191, 10.1016/S0092-8674(03)01077-8
Pawson, 2007, Dynamic control of signaling by modular adaptor proteins, Curr. Opin. Cell Biol., 19, 112, 10.1016/j.ceb.2007.02.013
Pedersen, 2001, The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy, Ann. Oncol., 12, 745, 10.1023/A:1011177318162
Pellegrini, 2000, Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin, Nature, 407, 1029, 10.1038/35039551
Pennock, 2008, A tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulation, Mol. Cell. Biol., 28, 3020, 10.1128/MCB.01809-07
Plotnikov, 1999, Structural basis for FGF receptor dimerization and activation, Cell, 98, 641, 10.1016/S0092-8674(00)80051-3
Qiu, 2008, Mechanism of activation and inhibition of the HER4/ErbB4 kinase, Structure, 16, 460, 10.1016/j.str.2007.12.016
Red Brewer, 2009, The juxtamembrane region of the EGF receptor functions as an activation domain, Mol. Cell, 34, 641, 10.1016/j.molcel.2009.04.034
Reichert, 2007, Development trends for monoclonal antibody cancer therapeutics, Nat. Rev. Drug Discov., 6, 349, 10.1038/nrd2241
Reynolds, 2003, EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation, Nat. Cell Biol., 5, 447, 10.1038/ncb981
Rohmann, 2006, Mutations in different components of FGF signaling in LADD syndrome, Nat. Genet., 38, 414, 10.1038/ng1757
Runeberg-Roos, 2007, Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases, Ann. Med., 39, 572, 10.1080/07853890701646256
Sadowski, 2009, Signaling from endosomes: location makes a difference, Exp. Cell Res., 315, 1601, 10.1016/j.yexcr.2008.09.021
Santos, 2007, Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate, Nat. Cell Biol., 9, 324, 10.1038/ncb1543
Sasaki, 2006, Structural basis for Gas6-Axl signalling, EMBO J., 25, 80, 10.1038/sj.emboj.7600912
Schlee, 2006, Quantitative analysis of the activation mechanism of the multicomponent growth-factor receptor Ret, Nat. Chem. Biol., 2, 636, 10.1038/nchembio823
Schlessinger, 2000, Cell signaling by receptor tyrosine kinases, Cell, 103, 211, 10.1016/S0092-8674(00)00114-8
Schlessinger, 2002, All signaling is local?, Mol. Cell, 10, 218, 10.1016/S1097-2765(02)00607-X
Schlessinger, 2003, SH2 and PTB domains in tyrosine kinase signaling, Sci. STKE, 191, RE12
Schlessinger, 2000, Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization, Mol. Cell, 6, 743, 10.1016/S1097-2765(00)00073-3
Schulze, 2004, The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component, Mol. Biol. Cell, 15, 3450, 10.1091/mbc.E03-11-0807
Seet, 2006, Reading protein modifications with interaction domains, Nat. Rev. Mol. Cell Biol., 7, 473, 10.1038/nrm1960
Seiradake, 2010, An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly, Nat. Struct. Mol. Biol., 17, 398, 10.1038/nsmb.1782
Sergina, 2007, The HER family and cancer: emerging molecular mechanisms and therapeutic targets, Trends Mol. Med., 13, 527, 10.1016/j.molmed.2007.10.002
Sharma, 2007, Epidermal growth factor receptor mutations in lung cancer, Nat. Rev. Cancer, 7, 169, 10.1038/nrc2088
Shattuck, 2008, Met receptor contributes to trastuzumab resistance of Her2-overexpressing breast cancer cells, Cancer Res., 68, 1471, 10.1158/0008-5472.CAN-07-5962
Shawver, 2002, Smart drugs: Tyrosine kinase inhibitors in cancer therapy, Cancer Cell, 1, 117, 10.1016/S1535-6108(02)00039-9
Shewchuk, 2000, Structure of the Tie2 RTK domain: Self-inhibition by the nucleotide binding loop, activation loop, and C-terminal tail, Structure, 8, 1105, 10.1016/S0969-2126(00)00516-5
Shilo, 2005, Regulating the dynamics of EGF receptor signaling in space and time, Development, 132, 4017, 10.1242/dev.02006
Shrivastava, 1997, An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors, Mol. Cell, 1, 25, 10.1016/S1097-2765(00)80004-0
Sigismund, 2008, Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation, Dev. Cell, 15, 209, 10.1016/j.devcel.2008.06.012
Slamon, 1989, Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer, Science, 244, 707, 10.1126/science.2470152
Songyang, 2004, ZIP codes for delivering SH2 domains, Cell, 116, S41, 10.1016/S0092-8674(04)00041-8
Sorkin, 2009, Endocytosis and intracellular trafficking of ErbBs, Exp. Cell Res., 315, 683, 10.1016/j.yexcr.2008.07.029
Stauber, 2000, Structural interactions of fibroblast growth factor receptor with its ligands, Proc. Natl. Acad. Sci. USA, 97, 49, 10.1073/pnas.97.1.49
Stelling, 2004, Robustness of cellular functions, Cell, 118, 675, 10.1016/j.cell.2004.09.008
Stiegler, 2006, Crystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK, J. Mol. Biol., 364, 424, 10.1016/j.jmb.2006.09.019
Temin, 1966, Studies on carcinogenesis by avian sarcoma viruses. 3. The differential effect of serum and polyanions on multiplication of uninfected and converted cells, J. Natl. Cancer Inst., 37, 167
Till, 2002, Crystal structure of the MuSK tyrosine kinase: Insights into receptor autoregulation, Structure, 10, 1187, 10.1016/S0969-2126(02)00814-6
Tonks, 2006, Protein tyrosine phosphatases: from genes, to function, to disease, Nat. Rev. Mol. Cell Biol., 7, 833, 10.1038/nrm2039
Tvorogov, 2002, EGF-dependent association of phospholipase C-gamma1 with c-Cbl, Exp. Cell Res., 277, 86, 10.1006/excr.2002.5545
Ueki, 1994, Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation, J. Biol. Chem., 269, 15756, 10.1016/S0021-9258(17)40745-9
Ullrich, 1990, Signal transduction by receptors with tyrosine kinase activity, Cell, 61, 203, 10.1016/0092-8674(90)90801-K
van Amerongen, 2008, Alternative wnt signaling is initiated by distinct receptors, Sci. Signal., 2, re9
Vogel, 1997, The discoidin domain receptor tyrosine kinases are activated by collagen, Mol. Cell, 1, 13, 10.1016/S1097-2765(00)80003-9
von Zastrow, 2007, Signaling on the endocytic pathway, Curr. Opin. Cell Biol., 19, 436, 10.1016/j.ceb.2007.04.021
Waksman, 2004, Structure and specificity of the SH2 domain, Cell, 116, S45, 10.1016/S0092-8674(04)00043-1
Walton, 1990, Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates, J. Biol. Chem., 265, 1750, 10.1016/S0021-9258(19)40080-X
Wang, 2004, Platelet-derived growth factor receptor-mediated signal transduction from endosomes, J. Biol. Chem., 279, 8038, 10.1074/jbc.M311494200
Ward, 2007, The insulin and EGF receptor structures: new insights into ligand-induced receptor activation, Trends Biochem. Sci., 32, 129, 10.1016/j.tibs.2007.01.001
Waterfield, 1983, Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus, Nature, 304, 35, 10.1038/304035a0
Wehrman, 2007, Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors, Neuron, 53, 25, 10.1016/j.neuron.2006.09.034
Wiesmann, 1997, Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor, Cell, 91, 695, 10.1016/S0092-8674(00)80456-0
Wiesmann, 1999, Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor, Nature, 401, 184, 10.1038/43705
Wybenga-Groot, 2001, Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region, Cell, 106, 745, 10.1016/S0092-8674(01)00496-2
York, 1998, Rap1 mediates sustained MAP kinase activation induced by nerve growth factor, Nature, 392, 622, 10.1038/33451
Yuzawa, 2007, Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor, Cell, 130, 323, 10.1016/j.cell.2007.05.055
Zhang, 2006, An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor, Cell, 125, 1137, 10.1016/j.cell.2006.05.013
Zwang, 2009, Systems biology of growth factor-induced receptor endocytosis, Traffic, 10, 349, 10.1111/j.1600-0854.2008.00870.x