Task-specificity vs. ceiling effect: Step-training in shallow water after spinal cord injury

Barbeau, 1987, Recovery of locomotion after chronic spinalization in the adult cat, Brain Res., 412, 84, 10.1016/0006-8993(87)91442-9 Basso, 1995, A sensitive and reliable locomotor rating scale for open field testing in rats, J. Neurotrauma, 12, 1, 10.1089/neu.1995.12.1 Basso, 1996, MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study, J. Neurotrauma, 13, 343, 10.1089/neu.1996.13.343 Bouyer, 2003, Contribution of cutaneous inputs from the hindpaw to the control of locomotion. II. Spinal cats, J. Neurophysiol., 90, 3640, 10.1152/jn.00497.2003 Boyce, 2007, Neurotrophic factors promote and enhance locomotor recovery in untrained spinalized cats, J. Neurophysiol., 98, 1988, 10.1152/jn.00391.2007 Cha, 2007, Locomotor ability in spinal rats is dependent on the amount of activity imposed on the hindlimbs during treadmill training, J. Neurotrauma, 24, 1000, 10.1089/neu.2006.0233 Cheng, 1997, Gait analysis of adult paraplegic rats after spinal cord repair, Exp. Neurol., 148, 544, 10.1006/exnr.1997.6708 Courtine, 2009, Transformation of nonfunctional spinal circuits into functional states after the loss of brain input, Nat. Neurosci., 12, 1333, 10.1038/nn.2401 Cowley, 1994, A comparison of motor patterns induced by N-methyl-d-aspartate, acetylcholine and serotonin in the in vitro neonatal rat spinal cord, Neurosci. Lett., 171, 147, 10.1016/0304-3940(94)90626-2 Dietz, 2004, Recovery from spinal cord injury—underlying mechanisms and efficacy of rehabilitation, Acta Neurochir. Suppl., 89, 95, 10.1007/978-3-7091-0603-7_13 Dobkin, 2007, The evolution of walking-related outcomes over the first 12weeks of rehabilitation for incomplete traumatic spinal cord injury: the multicenter randomized Spinal Cord Injury Locomotor Trial, Neurorehabil. Neural Repair, 21, 25, 10.1177/1545968306295556 Edgerton, 1992, Potential of adult mammalian lumbosacral spinal cord to execute and acquire improved locomotion in the absence of supraspinal input, J. Neurotrauma, 9, S119 Edgerton, 2001, Retraining the injured spinal cord, J. Physiol., 533, 15, 10.1111/j.1469-7793.2001.0015b.x Fouad, 2000, Treadmill training in incomplete spinal cord injured rats, Behav. Brain Res., 115, 107, 10.1016/S0166-4328(00)00244-8 Hamers, 2001, Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries, J. Neurotrauma, 18, 187, 10.1089/08977150150502613 Harkema, 1997, Human lumbosacral spinal cord interprets loading during stepping, J. Neurophysiol., 77, 797, 10.1152/jn.1997.77.2.797 Heng, 2009, Treadmill training enhances the recovery of normal stepping patterns in spinal cord contused rats, Exp. Neurol., 216, 139, 10.1016/j.expneurol.2008.11.023 Koopmans, 2005, The assessment of locomotor function in spinal cord injured rats: the importance of objective analysis of coordination, J. Neurotrauma, 22, 214, 10.1089/neu.2005.22.214 Kunkel-Bagden, 1993, Methods to assess the development and recovery of locomotor function after spinal cord injury in rats, Exp. Neurol., 119, 153, 10.1006/exnr.1993.1017 Liu, 2005, Stimulation of the parapyramidal region of the neonatal rat brain stem produces locomotor-like activity involving spinal 5-HT7 and 5-HT2A receptors, J. Neurophysiol., 94, 1392, 10.1152/jn.00136.2005 Lovely, 1986, Effects of training on the recovery of full-weight-bearing stepping in the adult spinal cat, Exp. Neurol., 92, 421, 10.1016/0014-4886(86)90094-4 Magnuson, 1997, Locomotor rhythm evoked by ventrolateral funiculus stimulation in the neonatal rat spinal cord in vitro, J. Neurophysiol., 77, 200, 10.1152/jn.1997.77.1.200 Magnuson, 1999, Comparing deficits following excitotoxic and contusion injuries in the thoracic and lumbar spinal cord of the adult rat, Exp. Neurol., 156, 191, 10.1006/exnr.1999.7016 Magnuson, 2005, Functional consequences of lumbar spinal cord contusion injuries in the adult rat, J. Neurotrauma, 22, 529, 10.1089/neu.2005.22.529 Magnuson, D.S.K., Smith, R.R., Brown, E.H., Enzmann, G., Angeli, C., Quesada, P.M., Burke, D.A., 2009. Swimming as a model of task-specific locomotor re-training after spinal cord injury in the rat. Neurorehab and Neural Repair 23 (6), 535–545. Multon, 2003, The effect of treadmill training on motor recovery after a partial spinal cord compression-injury in the adult rat, J. Neurotrauma, 20, 699, 10.1089/089771503767869935 Norrie, 2005, Reduced functional recovery by delaying motor training after spinal cord injury, J. Neurophysiol., 94, 255, 10.1152/jn.00970.2004 Scheff, 2003, Experimental modeling of spinal cord injury: characterization of a force-defined injury device, J. Neurotrauma, 20, 179, 10.1089/08977150360547099 Smith, 2006, Effects of swimming on functional recovery after incomplete spinal cord injury in rats, J. Neurotrauma, 23, 908, 10.1089/neu.2006.23.908 Smith, 2006, The Louisville Swim Scale: a novel assessment of hindlimb function following spinal cord injury in adult rats, J. Neurotrauma, 23, 1654, 10.1089/neu.2006.23.1654 Smith, 2009, Swim training initiated acutely after spinal cord injury is ineffective and induces extravasation in and around the epicenter, J. Neurotrauma, 26, 1017, 10.1089/neu.2008.0829 Stevens, 2006, Changes in soleus muscle function and fiber morphology with one week of locomotor training in spinal cord contusion injured rats, J. Neurotrauma, 23, 1671, 10.1089/neu.2006.23.1671 Thota, 2001, Recovery of locomotor function after treadmill training of incomplete spinal cord injured rats, Biomed. Sci. Instrum., 37, 63 Timoszyk, 2005, Hindlimb loading determines stepping quantity and quality following spinal cord transection, Brain Res., 1050, 180, 10.1016/j.brainres.2005.05.041 Ying, 2008, BDNF-exercise interactions in the recovery of symmetrical stepping after a cervical hemisection in rats, Neuroscience, 155, 1070, 10.1016/j.neuroscience.2008.06.057