SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

Cancer Cell - Tập 17 - Trang 41-52 - 2010
Hyun-Seok Kim1, Krish Patel2, Kristi Muldoon-Jacobs2, Kheem S. Bisht2, Nukhet Aykin-Burns3, J. Daniel Pennington2, Riet van der Meer4, Phuongmai Nguyen2, Jason Savage2, Kjerstin M. Owens5, Athanassios Vassilopoulos1, Ozkan Ozden2, Seong-Hoon Park2, Keshav K. Singh5, Sarki A. Abdulkadir4, Douglas R. Spitz3, Chu-Xia Deng1, David Gius2,6
1Genetics of Development and Disease Branch, NIDDK, NIH, Bethesda, MD, 20892, USA
2Molecular Radiation Oncology, Radiation Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA
3Free Radical and Radiation Biology Program, Department of Radiation Oncology, University of Iowa, Iowa City, IA 52242, USA
4Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, 37232 USA
5Department of Cancer Genetics, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
6Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232, USA

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