Role of fusion protein cleavage site in the virulence of Newcastle disease virus

Mayo, 2002, A summary of taxonomic changes recently approved by ICTV, Arch Virol, 147, 1655, 10.1007/s007050200039 Alexander, 1989 Krishnamurthy, 1997, Nucleotide sequences of the trailer, nucleocapsid protein genome sequence, J Gen Virol, 79, 2419, 10.1099/0022-1317-79-10-2419 Peeples, 1988, Newcastle disease virus replication, 45 Steward, 1993, RNA editing in Newcastle disease virus, J Gen Virol, 74, 2539, 10.1099/0022-1317-74-12-2539 Scheid, 1974, Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity by proteolytic cleavage of an inactive protein of Sendai virus, Virology, 57, 470, 10.1016/0042-6822(74)90187-1 Sergel-Germano, 1994, Mutations in the fusion peptide and heptad repeat regions of the Newcastle disease virus fusion protein block fusion, J Virol, 68, 7654, 10.1128/JVI.68.11.7654-7658.1994 Gotoh, 1992, Mammalian subtilisin-related proteinases in cleavage activation of the paramyxovirus fusion glycoproteins: superiority of furin/PACE to PC2 or PC1/PC3, J Virol, 66, 6391, 10.1128/JVI.66.11.6391-6397.1992 Fujii, 1999, Comparison of substrate specificities against the fusion glycoprotein of virulent Newcastle disease virus between a chick embryo fibroblast processing protease and mammalian subtilisin-like proteases, Microbiol Immunol, 43, 133, 10.1111/j.1348-0421.1999.tb02384.x Millar, 1988, Nucleotide sequence of the fusion and hemagglutinin-neuraminidase glycoprotein genes of Newcastle disease virus, strain Ulster: molecular basis for variations in pathogenicity between strains, J Gen Virol, 69, 613, 10.1099/0022-1317-69-3-613 Seal, 1995, Characterization of Newcastle disease virus isolates by RT-PCR coupled to direct nucleotide sequencing and development of sequence database for pathotype prediction and molecular epidemiologic analysis, J Clin Microbiol, 33, 2624, 10.1128/JCM.33.10.2624-2630.1995 Huang, 2001, High-level expression of a foreign gene from the most 3′-proximal locus of a recombinant Newcastle disease virus, J Gen Virol, 82, 1729, 10.1099/0022-1317-82-7-1729 Collins, 1996, Pathogenicity and phylogenetic evaluation of the variant Newcastle disease viruses termed pigeon PMV-1 viruses based on the nucleotide sequence of the fusion protein gene, Arch Virol, 141, 635, 10.1007/BF01718322 Peeters, 1999, Rescue of Newcastle disease virus from cloned cDNA: evidence that cleavability of the fusion protein is a major determinant for virulence, J Virol, 73, 5001, 10.1128/JVI.73.6.5001-5009.1999 Taubenberger, 1997, Initial genetic characterization of the 1918 Spanish influenza virus, Science, 275, 1793, 10.1126/science.275.5307.1793 Cabaleda, 2002, Fusogenic activity of reconstituted Newcastle disease virus envelopes: a role for the hemagglutinin-neuraminidase protein in the fusion process, Int J Biochem Cell Biol, 34, 403, 10.1016/S1357-2725(01)00127-3 Mebatsion, 2001, A recombinant Newcastle disease virus with low-level V protein expression is immunogenic and lacks pathogenicity for chicken embryos, J Virol, 75, 420, 10.1128/JVI.75.1.420-428.2001 Park, 2003, Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonistic ativity for the NDV V protein and the Nipah virus V, W, and C proteins, J Virol, 77, 1501, 10.1128/JVI.77.2.1501-1511.2003 Takimoto, 2002, Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxo-cell membrane fusion, J Virol, 76, 13028, 10.1128/JVI.76.24.13028-13033.2002 Duprex, 1999, The H gene of rodent brain-adapted measles virus confers neurovirulence to the Edmonston vaccine strain, J Virol, 73, 6916, 10.1128/JVI.73.8.6916-6922.1999 Skiadopoulos, 1999, Identification of mutations contributing to the temperature sensitive, cold-adapted, and attenuation phenotypes of the live-attenuated cold-passage 45 (cp45) human parainfluenza virus 3 candidate vaccine, J Virol, 73, 1374, 10.1128/JVI.73.2.1374-1381.1999 Skiadopoulos, 1998, Three amino acid substitutions in the L protein of the human parainfluenza virus type 3 cp45 live attenuated vaccine candidate contribute to its temperature-sensitive and attenuation pathotypes, J Virol, 72, 1762, 10.1128/JVI.72.3.1762-1768.1998 Racaniello, 1993, Poliovirus attenuation and pathogenesis in a transgenic mouse model for poliomyelitis, Dev Biol Stand, 78, 109 Takeda, 1998, Measles virus attenuation associated with transcriptional impediment and a few amino acid changes in the polymerase and accessory proteins, J Virol, 72, 8690, 10.1128/JVI.72.11.8690-8696.1998 Enjuanes, 1995, Molecular basis of transmissible gastroenteritis coronavirus (TGEV) epidemiology, 337 Bridgen, 2001, Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis, Proc Natl Acad Sci USA, 98, 664, 10.1073/pnas.98.2.664 Heise, 2000, A single amino acid change in nsP1 attenuates neurovirulence of the Sindbis-group alphavirus S.A.AR86, J Virol, 74, 4207, 10.1128/JVI.74.9.4207-4213.2000 Yang, 2002, Induction of inflammation by West Nile virus capsid through the caspase-9 apoptotic pathway, Emerg Infect Dis, 8, 1379, 10.3201/eid0812.020224 Price, 1997, Differential induction of cytotoxicity and apoptosis by influenza virus strains of differing virulence, J Gen Virol, 78, 2821, 10.1099/0022-1317-78-11-2821 Lewis, 1996, Alphavirus-induced apoptosis in mouse brains correlates with neurovirulence, J Virol, 70, 1828, 10.1128/JVI.70.3.1828-1835.1996 Lam, 1995, Apoptosis as a cause of death in chicken embryos inoculated with Newcastle disease virus, Microb Pathog, 19, 169, 10.1006/mpat.1995.0055 Lycke, 1987, Rabies virus infection of cultured rat sensory neurons, J Virol, 61, 2733, 10.1128/JVI.61.9.2733-2741.1987 Krishnamurthy, 2000, Recovery of a virulent strain of Newcastle disease virus from cloned cDNA: expression of a foreign gene results in growth retardation and attenuation, Virology, 278, 168, 10.1006/viro.2000.0618 Byrappa, 1995, A highly efficient procedure for site-specific mutagenesis of full length plasmids using vent DNA polymerase, Genome Res, 404, 10.1101/gr.5.4.404 Kommers, 2001, Virulence of pigeon-origin Newcastle disease virus isolates for domestic chickens, Avian Dis, 45, 906, 10.2307/1592870 Lana, 1988, Characterization of a battery of monoclonal antibodies for differentiation of Newcastle disease virus and Pigeon paramyxovirus-1 strains, Avian Dis, 32, 273, 10.2307/1590814