Non-coding RNA profile in lung cancer

Bjaanaes, 2014, Unique microRNA-profiles in EGFR-mutated lung adenocarcinomas, Int. J. Cancer, 135, 1812, 10.1002/ijc.28828 Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 68, 394, 10.3322/caac.21492 Cabili, 2011, Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses, Genes Dev., 25, 1915, 10.1101/gad.17446611 Chang, 2017, Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C, Cancer Lett., 402, 190, 10.1016/j.canlet.2017.06.002 Chang, 2017, Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C, Cancer Lett., 402, 190, 10.1016/j.canlet.2017.06.002 Chen, 2019, The PVT1/miR-216b/Beclin-1 regulates cisplatin sensitivity of NSCLC cells via modulating autophagy and apoptosis, Cancer Chemother. Pharmacol., 83, 921, 10.1007/s00280-019-03808-3 Chen, 2016, LncRNA CCAT2 predicts poor prognosis and regulates growth and metastasis in small cell lung cancer, Biomed. Pharmacother., 82, 583, 10.1016/j.biopha.2016.05.017 Chen, 2018, MiR-548c inhibits lung cancer cell proliferation through suppression of Galectin-3-mediated TLR4 signaling pathway, Int. J. Clin. Exp. Med., 11, 581 Chen, 2012, Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis, Int. J. Cancer, 130, 1620, 10.1002/ijc.26177 Chen, 2017, Long non-coding RNA SNHG20 promotes non-small cell lung cancer cell proliferation and migration by epigenetically silencing of P21 expression, Cell Death Dis., 8, 10.1038/cddis.2017.484 Cong, 2019, Long non-coding RNA linc00665 promotes lung adenocarcinoma progression and functions as ceRNA to regulate AKR1B10-ERK signaling by sponging miR-98, Cell Death Dis., 10, 84, 10.1038/s41419-019-1361-3 Cui, 2017, Upregulated lncRNA SNHG1 contributes to progression of non-small cell lung cancer through inhibition of miR-101-3p and activation of Wnt/beta-catenin signaling pathway, Oncotarget., 8, 17785, 10.18632/oncotarget.14854 Esfandi, 2019, The expression of CCAT2, UCA1, PANDA and GHET1 long non-coding RNAs in lung cancer, Rep. Biochem. Mol. Biol., 8 Esfandi, 2018, Expresní analýza OIP5-AS1 u nemalobuněčného karcinomu plic, Klinicka Onkol., 31, 260 Esfandi, 2019, Expression of long non-coding RNAs (lncRNAs) has been dysregulated in non-small cell lung cancer tissues, BMC Cancer, 19, 222, 10.1186/s12885-019-5435-5 Fan, 2016, Identification of serum miRNAs by nano-quantum dots microarray as diagnostic biomarkers for early detection of non-small cell lung cancer, Tumour Biol., 37, 7777, 10.1007/s13277-015-4608-3 Fang, 2016, Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression, Biochem. Biophys. Res. Commun., 478, 811, 10.1016/j.bbrc.2016.08.030 Fortunato, 2019, Circulating mir-320a promotes immunosuppressive macrophages M2 phenotype associated with lung cancer risk, Int. J. Cancer, 144, 2746, 10.1002/ijc.31988 Fu, 2019, LncRNA CASC11 promotes TGF-beta1, increases cancer cell stemness and predicts postoperative survival in small cell lung cancer, Gene., 704, 91, 10.1016/j.gene.2019.04.019 Gao, 2016, Plasma miR-324-3p and miR-1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma, Oncotarget., 7, 59664, 10.18632/oncotarget.11198 Geng, 2014, Five microRNAs in plasma as novel biomarkers for screening of early-stage non-small cell lung cancer, Respir. Res., 15, 149, 10.1186/s12931-014-0149-3 Gong, 2019, Analysis of survival-related lncRNA landscape identifies a role for LINC01537 in energy metabolism and lung cancer progression, Int. J. Mol. Sci., 20, 3713, 10.3390/ijms20153713 Gong, 2017, Association between well-characterized lung cancer lncRNA polymorphisms and platinum-based chemotherapy toxicity in Chinese patients with lung cancer, Acta Pharmacol. Sin., 38, 581, 10.1038/aps.2016.164 Gong, 2016, Association of well-characterized lung cancer lncRNA polymorphisms with lung cancer susceptibility and platinum-based chemotherapy response, Tumour Biol., 37, 8349, 10.1007/s13277-015-4497-5 Grimolizzi, 2017, Exosomal miR-126 as a circulating biomarker in non-small-cell lung cancer regulating cancer progression, Sci. Rep., 7, 15277, 10.1038/s41598-017-15475-6 Guan, 2018, Knockdown of lncRNA GHET1 suppresses cell proliferation, invasion and LATS1/YAP pathway in non small cell lung cancer, Cancer Biomarkers: Section A Dis. Markers, 21, 557, 10.3233/CBM-170431 Guerriero, 2017, Analysis of miRNA profiles identified miR-196a as a crucial mediator of aberrant PI3K/AKT signaling in lung cancer cells, Oncotarget., 8, 19172, 10.18632/oncotarget.13432 Guo, 2018, Knockdown of LncRNA PVT1 inhibits tumorigenesis in non-small-cell lung cancer by regulating miR-497 expression, Exp. Cell Res., 362, 172, 10.1016/j.yexcr.2017.11.014 Guo, 2019, Long non-coding RNA TUG1 enhances chemosensitivity in non-small cell lung cancer by impairing microRNA-221-dependent PTEN inhibition, Aging., 11, 7553, 10.18632/aging.102271 He, 2017, LncRNA FEZF1-AS1 enhances epithelial-mesenchymal transition (EMT) through suppressing E-cadherin and regulating WNT pathway in non-small cell lung cancer (NSCLC), Biomed. Pharmacother., 95, 331, 10.1016/j.biopha.2017.08.057 Hombach, 2016, Non-coding RNAs: classification, biology and functioning, Adv. Exp. Med. Biol., 937, 3, 10.1007/978-3-319-42059-2_1 Hu, 2016, Clinical significance of long non-coding RNA CASC8 rs10505477 polymorphism in lung cancer susceptibility, platinum-based chemotherapy response, and toxicity, Int. J. Environ. Res. Public Health, 13, 10.3390/ijerph13060545 Huang, 2016, LncRNA PVT1 overexpression is a poor prognostic biomarker and regulates migration and invasion in small cell lung cancer, Am. J. Transl. Res., 8, 5025 Inamura, 2017, Lung cancer: understanding its molecular pathology and the 2015 WHO classification, Front. Oncol., 7, 193, 10.3389/fonc.2017.00193 Jen, 2017, Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression, Mol. Cancer, 16, 104, 10.1186/s12943-017-0674-z Jiang, 2018, Long noncoding RNA (lncRNA) HOTAIR affects tumorigenesis and metastasis of non-small cell lung cancer by upregulating miR-613, Oncol. Res., 26, 725, 10.3727/096504017X15119467381615 Jiang, 2019, Long non-coding RNAs in lung cancer: regulation patterns, biologic function and diagnosis implications, Int. J. Oncol., 55, 585 Jiang, 2019, FBXL19-AS1 exerts oncogenic function by sponging miR-431-5p to regulate RAF1 expression in lung cancer, Biosci. Rep., 39, 10.1042/BSR20181804 Jiang, 2017, Methylation of kruppel-like factor 2 (KLF2) associates with its expression and non-small cell lung cancer progression, Am. J. Transl. Res., 9, 2024 Jin, 2018, MiR-1269a acts as an onco-miRNA in non-small cell lung cancer via down-regulating SOX6, Eur. Rev. Med. Pharmacol. Sci., 22, 4888 Jin, 2017, Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non-small cell lung cancer using next-generation sequencing, Clin. Cancer Res., 23, 5311, 10.1158/1078-0432.CCR-17-0577 Kanaoka, 2018, Usefulness of plasma exosomal microRNA-451a as a noninvasive biomarker for early prediction of recurrence and prognosis of non-small cell lung cancer, Oncology., 94, 311, 10.1159/000487006 Kang, 2018, miR-33a inhibits cell proliferation and invasion by targeting CAND1 in lung cancer, Clin. Transl. Oncol., 20, 457, 10.1007/s12094-017-1730-2 Kim, 2016, Hsa-miR-1246 and hsa-miR-1290 are associated with stemness and invasiveness of non-small cell lung cancer, Lung Cancer, 91, 15, 10.1016/j.lungcan.2015.11.013 Kong, 2018, miR-641 functions as a tumor suppressor by targeting MDM2 in human lung cancer, Oncol. Res. Featur. Preclin. Clin. Cancer Therapeut., 26, 735 Li, 2017, Regulation of EMT by STAT3 in gastrointestinal cancer (review), Int. J. Oncol., 50, 753, 10.3892/ijo.2017.3846 Li, 2016, MicroRNA-490 regulates lung cancer metastasis by targeting poly r(C)-binding protein 1, Tumour Biol., 37, 15221, 10.1007/s13277-016-5347-9 Li, 2016, LncRNA MALAT1 exerts oncogenic functions in lung adenocarcinoma by targeting miR-204, Am. J. Cancer Res., 6, 1099 Li, 2018, Long non-coding RNA linc00460 promotes epithelial-mesenchymal transition and cell migration in lung cancer cells, Cancer Lett., 420, 80, 10.1016/j.canlet.2018.01.060 Li, 2019, Identification of lncRNA biomarkers in lung squamous cell carcinoma using comprehensive analysis of lncRNA mediated ceRNA network, Artif. Cell Nanomed. Biotechnol., 47, 3246, 10.1080/21691401.2019.1647225 Li, 2018, The lncRNA MALAT1 contributes to non-small cell lung cancer development via modulating miR-124/STAT3 axis, J. Cell. Physiol., 233, 6679, 10.1002/jcp.26325 Li, 2016, Upregulated long non-coding RNA AGAP2-AS1 represses LATS2 and KLF2 expression through interacting with EZH2 and LSD1 in non-small-cell lung cancer cells, Cell Death Dis., 7, 10.1038/cddis.2016.126 Li, 2018, Identification of ceRNA network based on a RNA-seq shows prognostic lncRNA biomarkers in human lung adenocarcinoma, Oncol. Lett., 16, 5697 Li, 2016, MicroRNA-455 suppresses non-small cell lung cancer through targeting ZEB1, Cell Biol. Int., 40, 621, 10.1002/cbin.10584 Liao, 2018, lncRNA CCHE1 increased proliferation, metastasis and invasion of non-small lung cancer cells and predicted poor survival in non-small lung cancer patients, Eur. Rev. Med. Pharmacol. Sci., 22, 1686 Lin, 2018, Comprehensive identification of microRNA arm selection preference in lung cancer: miR-324-5p and-3p serve oncogenic functions in lung cancer, Oncol. Lett., 15, 9818 Lin, 2016, Long noncoding RNA TUG1 is downregulated in non-small cell lung cancer and can regulate CELF1 on binding to PRC2, BMC Cancer, 16, 583, 10.1186/s12885-016-2569-6 Liu, 2019, LncRNA TP73-AS1 promoted the progression of lung adenocarcinoma via PI3K/AKT pathway, Biosci. Rep., 39, 10.1042/BSR20180999 Liu, 2018, Upregulated lncRNA ADAMTS9-AS2 suppresses progression of lung cancer through inhibition of miR-223-3p and promotion of TGFBR3, IUBMB Life, 70, 536, 10.1002/iub.1752 Liu, 2019, Long noncoding RNA MNX1-AS1 contributes to lung cancer progression through the miR-527/BRF2 pathway, J. Cell. Physiol., 234, 13843, 10.1002/jcp.28064 Liu, 2020, lncRNA SLC16A1-AS1 as a novel prognostic biomarker in non-small cell lung cancer, J. Investig. Med., 68, 52, 10.1136/jim-2019-001080 Liu, 2019, lncRNA HNF1A-AS1 modulates non-small cell lung cancer progression by targeting miR-149-5p/Cdk6, J. Cell. Biochem., 120, 18736, 10.1002/jcb.29186 Liu, 2017, Circulating exosomal microRNAs as prognostic biomarkers for non-small-cell lung cancer, Oncotarget., 8, 13048, 10.18632/oncotarget.14369 Liu, 2019, mirna-99b-5p targets FZD8 to inhibit non-small cell lung cancer proliferation, migration and invasion, OncoTargets Therapy, 12, 2615, 10.2147/OTT.S199196 Liu, 2017, Curcumin inhibits LIN-28A through the activation of miRNA-98 in the lung cancer cell line A549, Molecules., 22, 929, 10.3390/molecules22060929 Liu, 2018, TINCR suppresses proliferation and invasion through regulating miR-544a/FBXW7 axis in lung cancer, Biomed. Pharmacother., 99, 9, 10.1016/j.biopha.2018.01.049 Lu, 2017, MiRNA-107 enhances chemosensitivity to paclitaxel by targeting antiapoptotic factor Bcl-w in non small cell lung cancer, Am. J. Cancer Res., 7, 1863 Lu, 2018, LncRNA-DANCR contributes to lung adenocarcinoma progression by sponging miR-496 to modulate mTOR expression, J. Cell. Mol. Med., 22, 1527, 10.1111/jcmm.13420 Luo, 2016, miRNA-296-3p modulates chemosensitivity of lung cancer cells by targeting CX3CR1, Am. J. Transl. Res., 8, 1848 Ma, 2019, Long noncoding RNA LINC00460 promotes the Gefitinib resistance of nonsmall cell lung cancer through epidermal growth factor receptor by sponging miR-769-5p, DNA Cell Biol., 38, 176, 10.1089/dna.2018.4462 Ma, 2016, The tumor suppressive role of MiRNA-509-5p by targeting FOXM1 in non-small cell lung cancer, Cell. Physiol. Biochem., 38, 1435, 10.1159/000443086 MacFarlane, 2010, MicroRNA: biogenesis, function and role in cancer, Curr. Genomics, 11, 537, 10.2174/138920210793175895 Marchese, 2017, The multidimensional mechanisms of long noncoding RNA function, Genome Biol., 18, 206, 10.1186/s13059-017-1348-2 Miao, 2019, LncRNA HAND2-AS1 inhibits non-small cell lung cancer migration, invasion and maintains cell stemness through the interactions with TGF-beta1, Biosci. Rep., 39, 10.1042/BSR20181525 Miao, 2016, Loss of long noncoding RNA FOXF1-AS1 regulates epithelial-mesenchymal transition, stemness and metastasis of non-small cell lung cancer cells, Oncotarget., 7, 68339, 10.18632/oncotarget.11630 Mizuno, 2017, The microRNA expression signature of small cell lung cancer: tumor suppressors of miR-27a-5p and miR-34b-3p and their targeted oncogenes, J. Hum. Genet., 62, 671, 10.1038/jhg.2017.27 2014, Nature, 511, 543, 10.1038/nature13385 Network CGAR, 2012, Comprehensive genomic characterization of squamous cell lung cancers, Nature, 489, 519, 10.1038/nature11404 Niu, 2017, Long non-coding RNA TUG1 is involved in cell growth and chemoresistance of small cell lung cancer by regulating LIMK2b via EZH2, Mol. Cancer, 16, 5, 10.1186/s12943-016-0575-6 Ogunwobi, 2019, Chemoresistance mediated by ceRNA networks associated with the PVT1 locus, Front. Oncol., 9, 834, 10.3389/fonc.2019.00834 Pan, 2017, Long noncoding RNA FAL1 promotes cell proliferation, invasion and epithelial-mesenchymal transition through the PTEN/AKT signaling axis in non-small cell lung cancer, Cell. Physiol. Biochem., 43, 339, 10.1159/000480414 Pan, 2018, A two-miRNA signature (miR-33a-5p and miR-128-3p) in whole blood as potential biomarker for early diagnosis of lung cancer, Sci. Rep., 8, 16699, 10.1038/s41598-018-35139-3 Pastuszak-Lewandoska, 2016, Expression analysis of three miRNAs, miR-26a, miR-29b and miR-519d, in relation to MMP-2 expression level in non-small cell lung cancer patients: a pilot study, Med. Oncol., 33, 96, 10.1007/s12032-016-0815-z Peifer, 2012, Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer, Nat. Genet., 44, 1104, 10.1038/ng.2396 Peng, 2018, miRNA-19 promotes non-small-cell lung cancer cell proliferation via inhibiting CBX7 expression, OncoTargets Therapy, 11, 8865, 10.2147/OTT.S181433 Phillips, 2003, The stromal derived factor–1/CXCL12–CXC chemokine receptor 4 biological axis in non–small cell lung cancer metastases, Am. J. Respir. Crit. Care Med., 167, 1676, 10.1164/rccm.200301-071OC Powrózek, 2016, Application of plasma circulating microRNA-448, 506, 4316, and 4478 analysis for non-invasive diagnosis of lung cancer, Tumor Biol., 37, 2049, 10.1007/s13277-015-3971-4 Qi, 2018, lncRNA NEAT1 competes against let-7a to contribute to non-small cell lung cancer proliferation and metastasis, Biomed. Pharmacother., 103, 1507, 10.1016/j.biopha.2018.04.053 Qian, 2018, The lncRNA MIR4435-2HG promotes lung cancer progression by activating beta-catenin signalling, J. Mol. Med., 96, 753, 10.1007/s00109-018-1654-5 Rudin, 2012, Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer, Nat. Genet., 44, 1111, 10.1038/ng.2405 She, 2016, lncRNA-SNHG7 promotes the proliferation, migration and invasion and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression, Oncol. Rep., 36, 2673, 10.3892/or.2016.5105 Shen, 2018, MicroRNA-886-3P functions as a tumor suppressor in small cell lung cancer, Cancer Biol. Therapy, 19, 1185, 10.1080/15384047.2018.1491505 Shen, 2015, Long noncoding RNA MALAT1 promotes brain metastasis by inducing epithelial-mesenchymal transition in lung cancer, J. Neuro-Oncol., 121, 101, 10.1007/s11060-014-1613-0 Shen, 2018, LncRNA GHET1 predicts a poor prognosis of the patients with non-small cell lung cancer, Eur. Rev. Med. Pharmacol. Sci., 22, 2328 Sheng, 2019, A pathway-based strategy to identify biomarkers for lung cancer diagnosis and prognosis, Evol. Bioinformatics Online, 15 Sleightholm, 2017, Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy, Pharmacol. Ther., 179, 158, 10.1016/j.pharmthera.2017.05.012 Stinchcombe, 2016, Targeted therapies for lung cancer, Cancer Treat. Res., 170, 165, 10.1007/978-3-319-40389-2_8 Su, 2019, MiRNA-199 inhibits malignant progression of lung cancer through mediating RGS17, Eur. Rev. Med. Pharmacol. Sci., 23, 3390 Subat, 2018, Unique MicroRNA and mRNA Interactions in EGFR-Mutated Lung Adenocarcinoma, J. Clin. Med., 7, 10.3390/jcm7110419 Suetsugu, 2018, Downregulation of matrix metalloproteinase 14 by the antitumor miRNA, miR-150-5p, inhibits the aggressiveness of lung squamous cell carcinoma cells, Int. J. Oncol., 52, 913 Sun, 2016, MicroRNA-187-3p mitigates non-small cell lung cancer (NSCLC) development through down-regulation of BCL6, Biochem. Biophys. Res. Commun., 471, 82, 10.1016/j.bbrc.2016.01.175 Sun, 2016, Long intergenic noncoding RNA 00511 acts as an oncogene in non-small-cell lung cancer by binding to EZH2 and suppressing p57, Mol. Therapy Nucleic Acids, 5 Sun, 2016, Increased plasma miRNA-30a as a biomarker for non-small cell lung cancer, Med. Sci. Monitor, 22, 647, 10.12659/MSM.897330 Sun, 2018, Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a, Cell Death Dis., 9, 85, 10.1038/s41419-017-0113-5 Sun, 2019, LncRNA FOXC2 antisense transcript accelerates non-small-cell lung cancer tumorigenesis via silencing p15, Am. J. Transl. Res., 11, 4552 Tan, 2018, miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP), Cancer Lett., 428, 55, 10.1016/j.canlet.2018.04.028 Tang, 2018, CPNE1 is a target of miR-335-5p and plays an important role in the pathogenesis of non-small cell lung cancer, J. Exp. Clin. Cancer Res., 37, 131, 10.1186/s13046-018-0811-6 Tang, 2016, Radiation-induced miR-208a increases the proliferation and radioresistance by targeting p21 in human lung cancer cells, J. Exp. Clin. Cancer Res., 35, 7, 10.1186/s13046-016-0285-3 Tang, 2017, lncRNA XIST interacts with miR-140 to modulate lung cancer growth by targeting iASPP, Oncol. Rep., 38, 941, 10.3892/or.2017.5751 Ulitsky, 2018, Interactions between short and long noncoding RNAs, FEBS Lett., 592, 2874, 10.1002/1873-3468.13085 Wan, 2016, Knockdown of long noncoding RNA PCAT6 inhibits proliferation and invasion in lung cancer cells, Oncol. Res. Featur. Preclin. Clin. Cancer Therapeut., 24, 161 Wang, 2018, LncRNA PVT1 regulate expression of HIF1alpha via functioning as ceRNA for miR199a5p in nonsmall cell lung cancer under hypoxia, Mol. Med. Rep., 17, 1105 Wang, 2019, Long non-coding RNA PVT1 competitively binds microRNA-424-5p to regulate CARM1 in radiosensitivity of non-small-cell lung cancer, Mol. Therapy Nucleic Acids, 16, 130, 10.1016/j.omtn.2018.12.006 Wang, 2017, The long non-coding RNA XIST controls non-small cell lung cancer proliferation and invasion by modulating miR-186-5p, Cell. Physiol. Biochem., 41, 2221, 10.1159/000475637 Wang, 2018, MALAT1/miR-101-3p/MCL1 axis mediates cisplatin resistance in lung cancer, Oncotarget., 9, 7501, 10.18632/oncotarget.23483 Wang, 2018, miR-339-5p increases radiosensitivity of lung cancer cells by targeting phosphatases of regenerating liver-1 (PRL-1), Med. Sci. Monitor, 24, 8408, 10.12659/MSM.910808 Wang, 2017, LncRNA SNHG12 contributes to multidrug resistance through activating the MAPK/Slug pathway by sponging miR-181a in non-small cell lung cancer, Oncotarget., 8, 84086, 10.18632/oncotarget.20475 Wang, 2019, Clinical value of microRNA-198-5p downregulation in lung adenocarcinoma and its potential pathways, Oncol. Lett., 18, 2939 Wang, 2019, The construction and analysis of the aberrant lncRNA-miRNA-mRNA network in non-small cell lung cancer, J. Thoracic Dis., 11, 1772, 10.21037/jtd.2019.05.69 Wang, 2017, MiR-142-5p suppresses tumorigenesis by targeting PIK3CA in non-small cell lung cancer, Cell. Physiol. Biochem., 43, 2505, 10.1159/000484459 Wang, 2016, Oncogenic roles and drug target of CXCR4/CXCL12 axis in lung cancer and cancer stem cell, Tumor Biol., 37, 8515, 10.1007/s13277-016-5016-z Weber, 2013, Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer, BMC Res. Notes, 6, 518, 10.1186/1756-0500-6-518 Wu, 2017, Knockdown of Lncrna PVT1 enhances radiosensitivity in non-small cell lung cancer by sponging Mir-195, Cell. Physiol. Biochem., 42, 2453, 10.1159/000480209 Wu, 2018 Wu, 2016, Downregulation of the long noncoding RNA GAS5-AS1 contributes to tumor metastasis in non-small cell lung cancer, Sci. Rep., 6, 31093, 10.1038/srep31093 Wu, 2019, Downregulation of oncogenic gene TGFβR2 by miRNA-107 suppresses non-small cell lung cancer, Pathol. Res. Practice, 152690 Xiao, 2019, Prognostic value of microRNAs in lung cancer: a systematic review and meta-analysis, Mol. Clin. Oncol., 10, 67 Xu, 2018, MicroRNA-1246 inhibits cell invasion and epithelial mesenchymal transition process by targeting CXCR4 in lung cancer cells, Cancer Biomarkers, 21, 251, 10.3233/CBM-170317 Xu, 2019, Overexpression of lncRNA EGFRAS1 is associated with a poor prognosis and promotes chemotherapy resistance in nonsmall cell lung cancer, Int. J. Oncol., 54, 295 Xue, 2016, MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1, SOCS6, and PTEN, Oncotarget., 7, 84508, 10.18632/oncotarget.13022 Yang, 2016, Integrative analysis of microRNA and mRNA expression profiles in non-small-cell lung cancer, Cancer Gene Ther., 23, 90, 10.1038/cgt.2016.5 Yang, 2019, lncRNA BCAR4 increases viability, invasion, and migration of non-small cell lung cancer cells by targeting glioma-associated oncogene 2 (GLI2), Oncol. Res., 27, 359, 10.3727/096504018X15220594629967 Yang, 2019, LncRNA BX357664 inhibits the proliferation and invasion of non-small cell lung cancer cells, Eur. Rev. Med. Pharmacol. Sci., 23, 660 Yang, 2019, lncRNA LEF1-AS1 promotes malignancy in non-small-cell lung cancer by modulating the miR-489/SOX4 Axis, DNA Cell Biol., 38, 1013, 10.1089/dna.2019.4717 Ye, 2019, LncRNA LINC00460 promotes tumor growth of human lung adenocarcinoma by targeting miR-302c-5p/FOXA1 axis, Gene., 685, 76, 10.1016/j.gene.2018.10.058 Ye, 2016, miR-211 promotes non-small cell lung cancer proliferation by targeting SRCIN1, Tumor Biol., 37, 1151, 10.1007/s13277-015-3835-y Yu, 2019, Circulating microRNA biomarkers for lung cancer detection in East Asian populations, Cancers, 11, 10.3390/cancers11030415 Yuan, 2018, Long non-coding RNA LINC00339 facilitates the tumorigenesis of non-small cell lung cancer by sponging miR-145 through targeting FOXM1, Biomed. Pharmacother., 105, 707, 10.1016/j.biopha.2018.06.022 Zhai, 2016, miRNA-148b regulates radioresistance in non-small lung cancer cells via regulation of MutL homologue 1, Biosci. Rep., 36, 10.1042/BSR20150300 Zhang, 2019, Oncogenic microRNA-411 promotes lung carcinogenesis by directly targeting suppressor genes SPRY4 and TXNIP, Oncogene., 38, 1892, 10.1038/s41388-018-0534-3 Zhang, 2018, Long non-coding RNA HNF1A-AS1 promotes cell proliferation and invasion via regulating miR-17-5p in non-small cell lung cancer, Biomed. Pharmacother., 98, 594, 10.1016/j.biopha.2017.12.080 Zhang, 2017, Plasma miR-145, miR-20a, miR-21 and miR-223 as novel biomarkers for screening early-stage non-small cell lung cancer, Oncol. Lett., 13, 669, 10.3892/ol.2016.5462 Zhang, 2019, Identification of lung-adenocarcinoma-related long non-coding RNAs by random walking on a competing endogenous RNA network, Ann. Translat. Med., 7, 339, 10.21037/atm.2019.06.69 Zhang, 2018, LncRNA H19 promotes epithelial-mesenchymal transition (EMT) by targeting miR-484 in human lung cancer cells, J. Cell. Biochem., 119, 4447, 10.1002/jcb.26537 Zhang, 2017, Serum long non coding RNA MALAT-1 protected by exosomes is up-regulated and promotes cell proliferation and migration in non-small cell lung cancer, Biochem. Biophys. Res. Commun., 490, 406, 10.1016/j.bbrc.2017.06.055 Zhang, 2016, miRNA-204 suppresses human non-small cell lung cancer by targeting ATF2, Tumor Biol., 37, 11177, 10.1007/s13277-016-4906-4 Zhang, 2019, LncRNA NR2F2-AS1 promotes tumourigenesis through modulating BMI1 expression by targeting miR-320b in non-small cell lung cancer, J. Cell. Mol. Med., 23, 2001, 10.1111/jcmm.14102 Zhang, 2019, MiRNA-153-3p promotes gefitinib-sensitivity in non-small cell lung cancer by inhibiting ATG5 expression and autophagy, Eur. Rev. Med. Pharmacol. Sci., 23, 2444 Zhang, 2017, lncRNA LINC00152 knockdown had effects to suppress biological activity of lung cancer via EGFR/PI3K/AKT pathway, Biomed. Pharmacother., 94, 644, 10.1016/j.biopha.2017.07.120 Zhang, 2017, The lncRNA XIST exhibits oncogenic properties via regulation of miR-449a and Bcl-2 in human non-small cell lung cancer, Acta Pharmacol. Sin., 38, 371, 10.1038/aps.2016.133 Zhang, 2019, Long non-coding RNA SNHG14 exerts oncogenic functions in non-small cell lung cancer through acting as an miR-340 sponge, Biosci. Rep., 39, 10.1042/BSR20180941 Zhao, 2016, Over-expression of lncRNA SBF2-AS1 is associated with advanced tumor progression and poor prognosis in patients with non-small cell lung cancer, Eur. Rev. Med. Pharmacol. Sci., 20, 3031 Zhao, 2017, LncRNA CCAT2 promotes tumorigenesis by over-expressed Pokemon in non-small cell lung cancer, Biomed. Pharmacother., 87, 692, 10.1016/j.biopha.2016.12.122 Zhen, 2018, LncRNA DANCR promotes lung cancer by sequestering miR-216a, Cancer Control, 25, 10.1177/1073274818769849 Zhou, 2019, Long non-coding RNA LOC285194 functions as a tumor suppressor by targeting p53 in non-small cell lung cancer, Oncol. Rep., 41, 15 Zhou, 2016, MicroRNA-574-5p promotes metastasis of non-small cell lung cancer by targeting PTPRU, Sci. Rep., 6, 35714, 10.1038/srep35714 Zhu, 2019, Long noncoding RNA PART1 promotes progression of non-small cell lung cancer cells via JAK-STAT signaling pathway, Cancer Med., 8, 6064, 10.1002/cam4.2494 Zhu, 2017, Identification of a serum microRNA expression signature for detection of lung cancer, involving miR-23b, miR-221, miR-148b and miR-423-3p, Lung Cancer, 114, 6, 10.1016/j.lungcan.2017.10.002