The effects of early life stress on reward processing

Journal of Psychiatric Research - Tập 101 - Trang 80-103 - 2018
Andrew M. Novick1,2, Mateus L. Levandowski3, Laura E. Laumann1, Noah S. Philip1,2,4, Lawrence H. Price1,2, Audrey R. Tyrka1,2
1Mood Disorders Research Program and Laboratory for Clinical and Translational Neuroscience, Butler Hospital, Providence, RI, USA
2Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA
3Developmental Cognitive Neuroscience Lab (DCNL), Graduate Program in Psychology, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil
4Center for Neurorestoration and Neurotechnology, Providence VA, Providence, RI, USA

Tài liệu tham khảo

Acheson, 2013, Reward learning as a potential target for pharmacological augmentation of cognitive remediation for schizophrenia: a roadmap for preclinical development, Front. Neurosci., 7, 10.3389/fnins.2013.00103 Admon, 2016, Dopaminergic enhancement of striatal response to reward in major depression, Am. J. Psychiatr. Admon, 2015, Dysfunctional reward processing in depression, Curr. Opin. Psychol. Depression, 4, 114, 10.1016/j.copsyc.2014.12.011 Amiri, 2016, Involvement of D1 and D2 dopamine receptors in the antidepressant-like effects of selegiline in maternal separation model of mouse, Physiol. Behav., 163, 107, 10.1016/j.physbeh.2016.04.052 Amitai, 2014, Isolation rearing effects on probabilistic learning and cognitive flexibility in rats, Cognit. Affect Behav. Neurosci., 14, 388, 10.3758/s13415-013-0204-4 Andersen, 2009, Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuse, Neurosci. Biobehav. Rev., 33, 516, 10.1016/j.neubiorev.2008.09.009 Andersen, 2008, Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuse, Neurosci. Biobehav. Rev. Andersen, 2000, Dopamine receptor pruning in prefrontal cortex during the periadolescent period in rats, Synap. N. Y. N, 37, 167, 10.1002/1098-2396(200008)37:2<167::AID-SYN11>3.0.CO;2-B Andersen, 2008, Preliminary evidence for sensitive periods in the effect of childhood sexual abuse on regional brain development, J. Neuropsychiatry Clin. Neurosci., 20, 292, 10.1176/jnp.2008.20.3.292 Baarendse, 2013, Disrupted social development enhances the motivation for cocaine in rats, Psychopharmacology (Berl.), 231, 1695, 10.1007/s00213-013-3362-8 Bagosi, 2006, The effects of corticoptropin-releasing factor and the urocortins on striatal dopamine release induced by electrical stimulation—an in vitro superfusion study, Neurochem. Res., 31, 209, 10.1007/s11064-005-9010-x Bai, 2014, Comparison of depressive behaviors induced by three stress paradigms in rats, Physiol. Behav., 131, 81, 10.1016/j.physbeh.2014.04.019 Ball, 2009, Borderline personality disorder and childhood trauma: evidence for a causal relationship, Curr. Psychiatr. Rep., 11, 63, 10.1007/s11920-009-0010-4 Baranger, 2016, PER1 rs3027172 genotype interacts with early life stress to predict problematic alcohol use, but not reward-related ventral striatum activity, Front. Psychol., 7 Bardo, 2000, Conditioned place preference: what does it add to our preclinical understanding of drug reward?, Psychopharmacology (Berl.), 153, 31, 10.1007/s002130000569 Bayer, 1999, Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the “Two hit hypothesis.”, J. Psychiatr. Res., 33, 543, 10.1016/S0022-3956(99)00039-4 Berlin, 1998, Measures of anhedonia and hedonic responses to sucrose in depressive and schizophrenic patients in comparison with healthy subjects, Eur. Psychiatr., 13, 303, 10.1016/S0924-9338(98)80048-5 Berridge, 1998, What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?, Brain Res. Rev., 28, 309, 10.1016/S0165-0173(98)00019-8 Berridge, 2003, Parsing reward, Trends Neurosci., 26, 507, 10.1016/S0166-2236(03)00233-9 Birn, 2017, Early childhood stress exposure, reward pathways, and adult decision making, Proc. Natl. Acad. Sci. U. S. A, 114, 13549, 10.1073/pnas.1708791114 Boecker, 2014, Impact of early life adversity on reward processing in young adults: EEG-fMRI results from a prospective study over 25 years, PLoS One, 9, 10.1371/journal.pone.0104185 Boecker-Schlier, 2016, Interaction between COMT Val(158)Met polymorphism and childhood adversity affects reward processing in adulthood, Neuroimage, 132, 556, 10.1016/j.neuroimage.2016.02.006 Bolton, 2018, Anhedonia following early-life adversity involves aberrant interaction of reward and anxiety circuits and is reversed by partial silencing of amygdala corticotropin-releasing hormone gene, Biol. Psychiatr., 83, 137, 10.1016/j.biopsych.2017.08.023 Bourke, 2011, Behavioral effects of chronic adolescent stress are sustained and sexually dimorphic, Horm. Behav., 60, 112, 10.1016/j.yhbeh.2011.03.011 Brake, 2004, Influence of early postnatal rearing conditions on mesocorticolimbic dopamine and behavioural responses to psychostimulants and stressors in adult rats, Eur. J. Neurosci., 19, 1863, 10.1111/j.1460-9568.2004.03286.x Brenes, 2009, The effect of chronic fluoxetine on social isolation-induced changes on sucrose consumption, immobility behavior, and on serotonin and dopamine function in hippocampus and ventral striatum, Behav. Brain Res., 198, 199, 10.1016/j.bbr.2008.10.036 Brenes, 2008, Effects of environmental enrichment and social isolation on sucrose consumption and preference: associations with depressive-like behavior and ventral striatum dopamine, Neurosci. Lett., 436, 278, 10.1016/j.neulet.2008.03.045 Bryce, 2016, Perturbations in effort-related decision-making driven by acute stress and corticotropin-releasing factor, Neuropsychopharmacology, 41, 2147, 10.1038/npp.2016.15 Burke, 2014, Stress in adolescence and drugs of abuse in rodent models: role of dopamine, CRF, and HPA axis, Psychopharmacology (Berl.), 231, 1557, 10.1007/s00213-013-3369-1 Caldji, 2000, Variations in maternal care in infancy regulate the development of stress reactivity, Biol. Psychiatry, ADAA/NIMH Genetics, 48, 1164, 10.1016/S0006-3223(00)01084-2 Caldji, 2000, The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat, Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol, 22, 219, 10.1016/S0893-133X(99)00110-4 Carlyle, 2012, Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits, Dev. Psychopathol., 24, 1401, 10.1017/S095457941200079X Campbell, 2017, Chemogenetic activation of the lateral hypothalamus reverses early life stress-induced deficits in motivational drive, Eur. J. Neurosci., 46, 2285, 10.1111/ejn.13674 Carpenter, 2009, Effect of childhood emotional abuse and age on cortisol responsivity in adulthood, Biol. Psychiatr., 66, 69, 10.1016/j.biopsych.2009.02.030 Carr, 2013, The role of early life stress in adult psychiatric disorders: a systematic review according to childhood trauma subtypes, J. Nerv. Ment. Dis., 201, 1007, 10.1097/NMD.0000000000000049 Casement, 2014, Girls' challenging social experiences in early adolescence predict neural response to rewards and depressive symptoms, Dev. Cogn. Neurosci, 8, 18, 10.1016/j.dcn.2013.12.003 Casement, 2015, Life stress in adolescence predicts early adult reward-related brain function and alcohol dependence, Soc. Cognit. Affect Neurosci., 10, 416, 10.1093/scan/nsu061 Caspi, 2003, Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene, Science, 301, 386, 10.1126/science.1083968 Castellanos-Ryan, 2011, Response inhibition and reward response bias mediate the predictive relationships between impulsivity and sensation seeking and common and unique variance in conduct disorder and substance misuse, Alcohol Clin. Exp. Res., 35, 140, 10.1111/j.1530-0277.2010.01331.x Clancy, 2001, Translating developmental time across mammalian species, Neuroscience, 105, 7, 10.1016/S0306-4522(01)00171-3 Colonnello, 2011, Brief periods of positive peer interactions mitigate the effects of total social isolation in young Octodon degus, Dev. Psychobiol., 53, 280, 10.1002/dev.20520 Corral-Frías, 2015, Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology, Psychol. Med., 45, 2605, 10.1017/S0033291715000525 Craenenbroeck, 2005, Role of glucocorticoids in dopamine-related neuropsychiatric disorders, Mol. Cell. Endocrinol., 245, 10, 10.1016/j.mce.2005.10.007 Cuenya, 2015, Postweaning isolation affects responses to incentive contrast in adulthood, Dev. Psychobiol., 57, 177, 10.1002/dev.21273 del Arco, 2008, Prefrontal cortex-nucleus accumbens interaction: in vivo modulation by dopamine and glutamate in the prefrontal cortex, Pharmacol. Biochem. Behav., 90, 226, 10.1016/j.pbb.2008.04.011 Delavari, 2016, Maternal separation and the risk of drug abuse in later life, Addict. Health, 8, 107 Dennison, 2016, Neurobehavioral markers of resilience to depression amongst adolescents exposed to child abuse, J. Abnorm. Psychol., 125, 1201, 10.1037/abn0000215 Dillon, 2009, Childhood adversity is associated with left basal ganglia dysfunction during reward anticipation in adulthood, Biol. Psychiatr., 66, 206, 10.1016/j.biopsych.2009.02.019 Dunn, 2008, The role of corticotropin-releasing factor and noradrenaline in stress-related responses, and the inter-relationships between the two systems, Eur. J. Pharmacol., 583, 186, 10.1016/j.ejphar.2007.11.069 Enoch, 2012, The influence of gene-environment interactions on the development of alcoholism and drug dependence, Curr. Psychiatr. Rep., 14, 150, 10.1007/s11920-011-0252-9 Fabricius, 2010, Increased dopaminergic activity in socially isolated rats: an electrophysiological study, Neurosci. Lett., 482, 117, 10.1016/j.neulet.2010.07.014 Ferreira, 2013, Vulnerability to dietary n-3 polyunsaturated fatty acid deficiency after exposure to early stress in rats, Pharmacol. Biochem. Behav., 107, 11, 10.1016/j.pbb.2013.03.006 Flagel, 2009, Individual differences in the attribution of incentive salience to reward-related cues: implications for addiction, Neuropharmacology, 56, 139, 10.1016/j.neuropharm.2008.06.027 Fone, 2008, Behavioural and neurochemical effects of post-weaning social isolation in rodents—relevance to developmental neuropsychiatric disorders, Neurosci. Biobehav. Rev., The long-term consequences of stress on brain function: from adaptation to mental diseases, 32, 1087 Galvan, 2006, Earlier development of the accumbens relative to orbitofrontal cortex might underlie risk-taking behavior in adolescents, J. Neurosci., 26, 6885, 10.1523/JNEUROSCI.1062-06.2006 Garfield, 2014, Anhedonia in substance use disorders: a systematic review of its nature, course and clinical correlates, Aust. N. Z. J. Psychiatr., 48, 36, 10.1177/0004867413508455 Garland, 2016, Restructuring reward processing with Mindfulness-Oriented Recovery Enhancement: novel therapeutic mechanisms to remediate hedonic dysregulation in addiction, stress, and pain, Ann. N. Y. Acad. Sci., 1373, 25, 10.1111/nyas.13034 George, 2012, Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems, Physiol. Behav., 106, 58, 10.1016/j.physbeh.2011.11.004 Goff, 2013, Reduced nucleus accumbens reactivity and adolescent depression following early-life stress, Neuroscience, 249, 129, 10.1016/j.neuroscience.2012.12.010 Gradin, 2011, Expected value and prediction error abnormalities in depression and schizophrenia, Brain, 134, 1751, 10.1093/brain/awr059 Guyer, 2006, Behavioral alterations in reward system function: the role of childhood maltreatment and psychopathology, J. Am. Acad. Child Adolesc. Psychiatry, 45, 1059, 10.1097/01.chi.0000227882.50404.11 Hall, 1999, Maternal deprivation of neonatal rats produces enduring changes in dopamine function, Synapse, 32, 37, 10.1002/(SICI)1098-2396(199904)32:1<37::AID-SYN5>3.0.CO;2-4 Hall, 1998, Effects of isolation-rearing on voluntary consumption of ethanol, sucrose and saccharin solutions in Fawn Hooded and Wistar rats, Psychopharmacology (Berl.), 139, 210, 10.1007/s002130050706 Hall, 1997, The effects of isolation-rearing on sucrose consumption in rats, Physiol. Behav., 62, 291, 10.1016/S0031-9384(97)00116-9 Hall, 1998, Isolation rearing in rats: pre- and postsynaptic changes in striatal dopaminergic systems, Pharmacol. Biochem. Behav., 59, 859, 10.1016/S0091-3057(97)00510-8 Hanson, 2016, Cumulative stress in childhood is associated with blunted reward-related brain activity in adulthood, Soc. Cognit. Affect Neurosci., 11, 405, 10.1093/scan/nsv124 Hanson, 2015, Blunted ventral striatum development in adolescence reflects emotional neglect and predicts depressive symptoms, Biol. Psychiatr., 78, 598, 10.1016/j.biopsych.2015.05.010 Hanson, 2017, Early adversity and learning: implications for typical and atypical behavioral development, JCPP (J. Child Psychol. Psychiatry), 58, 770, 10.1111/jcpp.12694 Harlow, 1959, Love in infant monkeys, Sci. Am., 200, 68, 10.1038/scientificamerican0659-68 Harold, 2013, Biological and rearing mother influences on child ADHD symptoms: revisiting the developmental interface between nature and nurture, JCPP (J. Child Psychol. Psychiatry), 54, 1038, 10.1111/jcpp.12100 Heidbreder, 2000, Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome, Neuroscience, 100, 749, 10.1016/S0306-4522(00)00336-5 Heim, 2012, Current research trends in early life stress and depression: review of human studies on sensitive periods, gene–environment interactions, and epigenetics, Exp. Neurol., Special Issue: Stress and neurological disease, 233, 102, 10.1016/j.expneurol.2011.10.032 Heim, 2000, PItuitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood, JAMA, 284, 592, 10.1001/jama.284.5.592 Hill, 2014, Sex-specific disruptions in spatial memory and anhedonia in a “two hit” rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling, Hippocampus, 24, 1197, 10.1002/hipo.22302 Hofer, 1996, On the nature and consequences of early loss, Psychosom. Med., 58, 570, 10.1097/00006842-199611000-00005 Hoffman, 2015 Holson, 1991, “Isolation stress” revisited: isolation-rearing effects depend on animal care methods, Physiol. Behav., 49, 1107, 10.1016/0031-9384(91)90338-O Holz, 2017, Ventral striatum and amygdala activity as convergence sites for early adversity and conduct disorder, Soc. Cognit. Affect Neurosci., 12, 261, 10.1093/scan/nsw120 Hong, 2012, Social isolation in adolescence alters behaviors in the forced swim and sucrose preference tests in female but not in male rats, Physiol. Behav., 105, 269, 10.1016/j.physbeh.2011.08.036 Hui, 2011, Hippocampal neurochemistry is involved in the behavioural effects of neonatal maternal separation and their reversal by post-weaning environmental enrichment: a magnetic resonance study, Behav. Brain Res., 217, 122, 10.1016/j.bbr.2010.10.014 Huston, 2013, What's conditioned in conditioned place preference?, Trends Pharmacol. Sci., 34, 162, 10.1016/j.tips.2013.01.004 Jansma, 2013, THC reduces the anticipatory nucleus accumbens response to reward in subjects with a nicotine addiction, Transl. Psychiatry, 3, e234, 10.1038/tp.2013.6 Jones, 1990, Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens, Psychopharmacology (Berl.), 102, 364, 10.1007/BF02244105 Kalebasi, 2015, Blunted responses to reward in remitted post-traumatic stress disorder, Brain Behav, 5, 10.1002/brb3.357 Kalinichev, 2001, Early neonatal experience of Long-Evans rats results in long-lasting changes in morphine tolerance and dependence, Psychopharmacology (Berl.), 157, 305, 10.1007/s002130100806 Kalivas, 1987, Neurochemical and behavioral effects of corticotropin-releasing factor in the ventral tegmental area of the rat, J. Pharmacol. Exp. Ther, 242, 757 Klug, 2012, Chronic cannabinoid treatment during young adulthood induces sex-specific behavioural deficits in maternally separated rats, Behav. Brain Res., 233, 305, 10.1016/j.bbr.2012.05.019 Knutson, 2000, FMRI visualization of brain activity during a monetary incentive delay task, Neuroimage, 12, 20, 10.1006/nimg.2000.0593 Kosten, 2006, Early life stress impairs fear conditioning in adult male and female rats, Brain Res., 1087, 142, 10.1016/j.brainres.2006.03.009 Kundakovic, 2013, Sex-specific and strain-dependent effects of early life adversity on behavioral and epigenetic outcomes, Front. Psychiatry, 4, 10.3389/fpsyt.2013.00078 Ladd, 2000, Chapter 7-Long-term behavioral and neuroendocrine adaptations to adverse early experience, 81 Leão, 2007, Programming effects of antenatal dexamethasone in the developing mesolimbic pathways, Synapse, 61, 40, 10.1002/syn.20341 Lehmann, 2000, Long-term biobehavioral effects of maternal separation in the rat: consistent or confusing?, Rev. Neurosci., 11, 383, 10.1515/REVNEURO.2000.11.4.383 Levine, 1957, Infantile experience and resistance to physiological stress, Science, 126, 405, 10.1126/science.126.3270.405 Leussis, 2008, Is adolescence a sensitive period for depression? Behavioral and neuroanatomical findings from a social stress model, Synap. N. Y. N, 62, 22, 10.1002/syn.20462 Li, 2007, Chronic administration of clozapine alleviates reversal-learning impairment in isolation-reared rats, Behav. Pharmacol., 18, 135, 10.1097/FBP.0b013e3280d3ee83 Li, 2016, The effects of working memory training on enhancing hedonic processing to affective rewards in individuals with high social anhedonia, Psychiatry Res., 245, 482, 10.1016/j.psychres.2016.09.006 Lichtenberg, 2017, Basolateral amygdala to orbitofrontal cortex projections enable cue-triggered reward expectations, J. Neurosci., 37, 8374, 10.1523/JNEUROSCI.0486-17.2017 Liu, 2000, Influence of neonatal rearing conditions on stress-induced adrenocorticotropin responses and norepinepherine release in the hypothalamic paraventricular nucleus, J. Neuroendocrinol., 12, 5, 10.1046/j.1365-2826.2000.00422.x Liu, 2000, Maternal care, hippocampal synaptogenesis and cognitive development in rats, Nat. Neurosci., 3, 799, 10.1038/77702 Liu, 1997, Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress, Science, 277, 1659, 10.1126/science.277.5332.1659 Lomanowska, 2006, Artificial rearing alters the response of rats to natural and drug-mediated rewards, Dev. Psychobiol., 48, 301, 10.1002/dev.20139 Lukkes, 2009, Consequences of post-weaning social isolation on anxiety behavior and related neural circuits in rodents, Front. Behav. Neurosci., 3, 18, 10.3389/neuro.08.018.2009 Lutz Mahler, 2007, Endocannabinoid hedonic hotspot for sensory pleasure: anandamide in nucleus accumbens shell enhances “liking” of a sweet reward. Neuropsychopharmacol, Off. Publ. Am. Coll. Neuropsychopharmacol, 32, 2267, 10.1038/sj.npp.1301376 Maniam, 2010, Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment, Psychoneuroendocrinology, 35, 717, 10.1016/j.psyneuen.2009.10.013 Matthews, 1996, Retarded acquisition and reduced expression of conditioned locomotor activity in adult rats following repeated early maternal separation: effects of prefeeding,d, Psychopharmacology (Berl.), 126, 75, 10.1007/BF02246414 Matthews, 2003, Early experience as a determinant of adult behavioural responses to reward: the effects of repeated maternal separation in the rat, Neurosci. Biobehav. Rev., Brain Development, Sex Differences and Stress: Implications for Psychopathology, 27, 45, 10.1016/S0149-7634(03)00008-3 Matthews, 1996, Repeated maternal separation of preweanling rats attenuates behavioral responses to primary and conditioned incentives in adulthood, Physiol. Behav., 59, 99, 10.1016/0031-9384(95)02069-1 Maynard, 2001, Neural development, cell-cell signaling, and the “two-hit” hypothesis of schizophrenia, Schizophr. Bull., 27, 457, 10.1093/oxfordjournals.schbul.a006887 McCarthy, 2016, Inefficient effort allocation and negative symptoms in individuals with schizophrenia, Schizophr. Res., 170, 278, 10.1016/j.schres.2015.12.017 McCool, 2009, Early social isolation in male long-evans rats alters both appetitive and consummatory behaviors expressed during operant ethanol self-administration, Alcohol Clin. Exp. Res., 33, 273, 10.1111/j.1530-0277.2008.00830.x McCrory, 2010, Research Review: the neurobiology and genetics of maltreatment and adversity, JCPP (J. Child Psychol. Psychiatry), 51, 1079, 10.1111/j.1469-7610.2010.02271.x McCrory, 2017, Annual Research Review: childhood maltreatment, latent vulnerability and the shift to preventative psychiatry - the contribution of functional brain imaging, JCPP (J. Child Psychol. Psychiatry), 58, 338, 10.1111/jcpp.12713 McCrory, 2015, The theory of latent vulnerability: reconceptualizing the link between childhood maltreatment and psychiatric disorder, Dev. Psychopathol., 27, 493, 10.1017/S0954579415000115 Meaney, 2002, Environmental regulation of the development of mesolimbic dopamine systems: a neurobiological mechanism for vulnerability to drug abuse?, Psychoneuroendocrinology, 27, 127, 10.1016/S0306-4530(01)00040-3 Mehta, 2010, Hyporesponsive reward anticipation in the basal ganglia following severe institutional deprivation early in life, J. Cognit. Neurosci., 22, 2316, 10.1162/jocn.2009.21394 Michaels, 2006, Neonatal stress and litter composition alter sucrose intake in both rat dam and offspring, Physiol. Behav, 89, 735, 10.1016/j.physbeh.2006.08.015 Miller, 2012, Prolonged myelination in human neocortical evolution, Proc. Natl. Acad. Sci. U. S. A, 109, 16480, 10.1073/pnas.1117943109 Mills, 2014, The developmental mismatch in structural brain maturation during adolescence, Dev. Neurosci., 36, 147, 10.1159/000362328 Morgan, 2014, Maternal depression and warmth during childhood predict age 20 neural response to reward, J. Am. Acad. Child Adolesc. Psychiatry, 53, 108, 10.1016/j.jaac.2013.10.003 Morgan, 1975, Incentive motivation and behavioral inhibition in socially-isolated rats, Physiol. Behav., 15, 405, 10.1016/0031-9384(75)90250-4 Mori, 2016, Behavioral activation can normalize neural hypoactivation in subthreshold depression during a monetary incentive delay task, J. Affect. Disord., 189, 254, 10.1016/j.jad.2015.09.036 Mrdalj, 2016, Mild daily stressors in adulthood may counteract behavioural effects after constant presence of mother during early life, Physiol. Behav., 165, 313, 10.1016/j.physbeh.2016.08.018 Nelson, 2016, Blunted neural response to rewards as a prospective predictor of the development of depression in adolescent girls, Am. J. Psychiatr., 10.1176/appi.ajp.2016.15121524 NIMH » Research Domain Criteria (RDoC) [WWW Document]., URL https://www.nimh.nih.gov/research-priorities/rdoc/index.shtml (accessed 12.4.2017). Novick, 2013, Adolescent social defeat decreases spatial working memory performance in adulthood, Behav. Brain Funct. BBF, 9, 39, 10.1186/1744-9081-9-39 Øines, 2012, Neonatal maternal separation in male rats increases intestinal permeability and affects behavior after chronic social stress, Physiol. Behav., 105, 1058, 10.1016/j.physbeh.2011.11.024 Panksepp, 1981, The ontogeny of play in rats, Dev. Psychobiol., 14, 327, 10.1002/dev.420140405 Palma-Gudiel, 2016, An integrative review of methylation at the serotonin transporter gene and its dialogue with environmental risk factors, psychopathology and 5-HTTLPR, Neurosci. Biobehav. Rev., 72, 190, 10.1016/j.neubiorev.2016.11.011 Paul, 2000, Sucrose and quinine intake by maternally-deprived and control rhesus monkeys, Behav. Brain Res., 112, 127, 10.1016/S0166-4328(00)00173-X Pechtel, 2013, Disrupted reinforcement learning and maladaptive behavior in women with a history of childhood sexual abuse: a high-density event-related potential study, JAMA Psychiatry, 70, 499, 10.1001/jamapsychiatry.2013.728 Peciña, 2005, Hedonic hot spot in nucleus accumbens shell: where do mu-opioids cause increased hedonic impact of sweetness?, J. Neurosci. Off. J. Soc. Neurosci, 25, 11777, 10.1523/JNEUROSCI.2329-05.2005 Peciña, 2003, Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards, J. Neurosci, 23, 9395, 10.1523/JNEUROSCI.23-28-09395.2003 Phillips, 2005, Early adversity and the prospective prediction of depressive and anxiety disorders in adolescents, J. Abnorm. Child Psychol., 33, 13, 10.1007/s10802-005-0930-3 Piazza, 1996, Glucocorticoids have state-dependent stimulant effects on the mesencephalic dopaminergic transmission, Proc. Natl. Acad. Sci., 93, 8716, 10.1073/pnas.93.16.8716 Pisu, 2011, Down-regulation of hippocampal BDNF and Arc associated with improvement in aversive spatial memory performance in socially isolated rats, Behav. Brain Res., 222, 73, 10.1016/j.bbr.2011.03.021 Placek, 2013, Impairments in set-shifting but not reversal learning in the neonatal ventral hippocampal lesion model of schizophrenia: further evidence for medial prefrontal deficits, Behav. Brain Res., 256, 405, 10.1016/j.bbr.2013.08.034 Ploj, 2003, Long-term effects of short and long periods of maternal separation on brain opioid peptide levels in male Wistar rats, Neuropeptides, 37, 149, 10.1016/S0143-4179(03)00043-X Pohl, 2007, Repeated exposure to stress across the childhood-adolescent period alters rats' anxiety-and depression-like behaviors in adulthood: The importance of stressor type and gender, Behav. Neurosci, 121, 462, 10.1037/0735-7044.121.3.462 Pollak, 2015, Multilevel developmental approaches to understanding the effects of child maltreatment: recent advances and future challenges, Dev. Psychopathol., 27, 1387, 10.1017/S0954579415000826 Pryce, 2004, Deprivation of parenting disrupts development of homeostatic and reward systems in marmoset monkey offspring, Biol. Psychiatr., 56, 72, 10.1016/j.biopsych.2004.05.002 Pryce, 2005, Long-term effects of early-life environmental manipulations in rodents and primates: potential animal models in depression research, Neurosci. Biobehav. Rev., Animal Models of Depression and Antidepressant Activity, 29, 649 Rizvi, 2016, Assessing anhedonia in depression: potentials and pitfalls, Neurosci. Biobehav. Rev., 65, 21, 10.1016/j.neubiorev.2016.03.004 Robbins, 2016, Neurobehavioural sequelae of social deprivation in rodents revisited: modelling social adversity for developmental neuropsychiatric disorders, J. Psychopharmacol. Oxf. Engl, 30, 1082, 10.1177/0269881116664450 Rolls, 2016, A non-reward attractor theory of depression, Neurosci. Biobehav. Rev., 68, 47, 10.1016/j.neubiorev.2016.05.007 Rubia, 2009, Disorder-specific dissociation of orbitofrontal dysfunction in boys with pure conduct disorder during reward and ventrolateral prefrontal dysfunction in boys with pure ADHD during sustained attention, Am. J. Psychiatr., 166, 83, 10.1176/appi.ajp.2008.08020212 Rüedi-Bettschen, 2005, Early deprivation under specific conditions leads to reduced interest in reward in adulthood in Wistar rats, Behav. Brain Res., 156, 297, 10.1016/j.bbr.2004.06.001 Rushworth, 2011, Frontal cortex and reward-guided learning and decision-making, Neuron, 70, 1054, 10.1016/j.neuron.2011.05.014 Sadeghi, 2016, Adolescent voluntary exercise attenuated hippocampal innate immunity responses and depressive-like behaviors following maternal separation stress in male rats, Physiol. Behav., 163, 177, 10.1016/j.physbeh.2016.05.017 Saji, 2013, Acute NK₁ receptor antagonist administration affects reward incentive anticipation processing in healthy volunteers, Int. J. Neuropsychopharmacol., 16, 1461, 10.1017/S1461145712001678 Salamone, 2002, Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine, Behav. Brain Res., 137, 3, 10.1016/S0166-4328(02)00282-6 Sánchez, 2001, Early adverse experience as a developmental risk factor for later psychopathology: evidence from rodent and primate models, Dev. Psychopathol., 13, 419, 10.1017/S0954579401003029 Sasagawa, 2017, Long-term effects of maternal separation coupled with social isolation on reward seeking and changes in dopamine D1 receptor expression in the nucleus accumbens via DNA methylation in mice, Neurosci. Lett., 641, 33, 10.1016/j.neulet.2017.01.025 Schneider, 1999, Growth and development following prenatal stress exposure in primates: an examination of ontogenetic vulnerability, Child Dev., 70, 263, 10.1111/1467-8624.00020 Schrijver, 2001, Early social deprivation disrupts attentional, but not affective, shifts in rats, Behav. Neurosci., 115, 437, 10.1037/0735-7044.115.2.437 Schultz, 2016, Dopamine reward prediction error coding, Dialogues Clin. Neurosci, 18, 23, 10.31887/DCNS.2016.18.1/wschultz Semple, 2013, Brain development in rodents and humans: identifying benchmarks of maturation and vulnerability to injury across species, Prog. Neurobiol., 0, 1, 10.1016/j.pneurobio.2013.04.001 Shalev, 2002, Repeated maternal separation does not alter sucrose-reinforced and open-field behaviors, Pharmacol. Biochem. Behav., 73, 115, 10.1016/S0091-3057(02)00756-6 Shu, 2015, Blunted behavioral and molecular responses to chronic mild stress in adult rats with experience of infancy maternal separation, Tohoku J. Exp. Med., 235, 81, 10.1620/tjem.235.81 Sinha, 2008, Chronic stress, drug use, and vulnerability to addiction, Ann. N. Y. Acad. Sci., 1141, 105, 10.1196/annals.1441.030 Smoski, 2011, Major depressive disorder is characterized by greater reward network activation to monetary than pleasant image rewards, Psychiatry Res., 194, 263, 10.1016/j.pscychresns.2011.06.012 Somerville, 2011, Frontostriatal maturation predicts cognitive control failure to appetitive cues in adolescents, J. Cognit. Neurosci., 23, 2123, 10.1162/jocn.2010.21572 Spitz, 1946, Anaclitic depression; an inquiry into the genesis of psychiatric conditions in early childhood, II, Psychoanal. Study Child, 2, 313, 10.1080/00797308.1946.11823551 Strüber, 2014, Impact of early adversity on glucocorticoid regulation and later mental disorders, Neurosci. Biobehav. Rev., 38, 17, 10.1016/j.neubiorev.2013.10.015 Suomi, 2008, Rigorous experiments on monkey love: an account of Harry F. Harlow's role in the history of attachment theory, Integr. Psychol. Behav. Sci., 42, 354, 10.1007/s12124-008-9072-9 Swinny, 2010, Neonatal rearing conditions distinctly shape locus coeruleus neuronal activity, dendritic arborization, and sensitivity to corticotrophin-releasing factor, Int. J. Neuropsychopharmacol. Off. Sci. J. Coll. Int. Neuropsychopharmacol. CINP, 13, 515 Takiguchi, 2015, Ventral striatum dysfunction in children and adolescents with reactive attachment disorder: functional MRI study, Br. J. Psychiatry Open, 1, 121, 10.1192/bjpo.bp.115.001586 Tarazi, 1999, Postnatal development of dopamine D1-like receptors in rat cortical and striatolimbic brain regions: an autoradiographic study, Dev. Neurosci., 21, 43, 10.1159/000017365 Tobler, 2016, Shared neural basis of social and non-social reward deficits in chronic cocaine users, Soc. Cognit. Affect Neurosci., 11, 1017, 10.1093/scan/nsw030 Toth, 2008, Age-dependent effects of chronic stress on brain plasticity and depressive behavior, J. Neurochem., 107, 522, 10.1111/j.1471-4159.2008.05642.x Tractenberg, 2016, An overview of maternal separation effects on behavioural outcomes in mice: evidence from a four-stage methodological systematic review, Neurosci. Biobehav. Rev., 68, 489, 10.1016/j.neubiorev.2016.06.021 Treadway, 2012, Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia, J. Abnorm. Psychol., 121, 553, 10.1037/a0028813 Tyrka, 2013, The neurobiological correlates of childhood adversity and implications for treatment, Acta Psychiatr. Scand., 128, 434, 10.1111/acps.12143 Tyrka, 2008, Childhood parental loss and adult hypothalamic-pituitary-adrenal function, Biol. Psychiatr., 63, 1147, 10.1016/j.biopsych.2008.01.011 Uchida, 2010, Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents, J. Neurosci., 30, 15007, 10.1523/JNEUROSCI.1436-10.2010 Valentino, 1983, Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus, Brain Res., 270, 363, 10.1016/0006-8993(83)90615-7 Van den Berg, 1999, Isolation changes the incentive value of sucrose and social behaviour in juvenile and adult rats, Behav. Brain Res., 106, 133, 10.1016/S0166-4328(99)00099-6 Van den Berg, 2000, Morphine attenuates the effects of juvenile isolation in rats, Neuropharmacology, 39, 969, 10.1016/S0028-3908(99)00216-6 van Hulst, 2016, Children with ADHD symptoms show decreased activity in ventral striatum during the anticipation of reward, irrespective of ADHD diagnosis, JCPP (J. Child Psychol. Psychiatry) Varese, 2012, Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective- and cross-sectional cohort studies, Schizophr. Bull., 38, 661, 10.1093/schbul/sbs050 Vazquez, 2005, Maternal deprivation increases vulnerability to morphine dependence and disturbs the enkephalinergic system in adulthood, J. Neurosci., 25, 4453, 10.1523/JNEUROSCI.4807-04.2005 Viveros, 1988, Effects of social isolation and crowding upon adrenocortical reactivity and behavior in the rat, Rev. Esp. Fisiol., 44, 315 Walsh, 2014, Stress gates neural activation of BDNF in the mesolimbic reward pathway, Nat. Neurosci., 17, 27, 10.1038/nn.3591 Wang, 2016, Using fMRI to study reward processing in humans: past, present, and future, J. Neurophysiol, 115, 1664, 10.1152/jn.00333.2015 Wassum, 2015, The basolateral amygdala in reward learning and addiction, Neurosci. BioBehav. Rev., 57, 271, 10.1016/j.neubiorev.2015.08.017 Weaver, 2004, Epigenetic programming by maternal behavior, Nat. Neurosci., 7, 847, 10.1038/nn1276 Weiss, 2004, Effect of social isolation on stress-related behavioural and neuroendocrine state in the rat, Behav. Brain Res., 152, 279, 10.1016/j.bbr.2003.10.015 Willner, 1996, Decreased hedonic responsiveness following chronic mild stress is not secondary to loss of body weight, Physiol. Behav., 60, 129, 10.1016/0031-9384(95)02256-2 Wyvell, 2000, Intra-accumbens amphetamine increases the conditioned incentive salience of sucrose reward: enhancement of reward "wanting" without enhanced "liking" or response reinforcement, J. Neurosci, 20, 8122, 10.1523/JNEUROSCI.20-21-08122.2000 Yorgason, 2016, Social isolation rearing increases dopamine uptake and psychostimulant potency in the striatum, Neuropharmacology, 101, 471, 10.1016/j.neuropharm.2015.10.025 Yorgason, 2013, Enduring increases in anxiety-like behavior and rapid nucleus accumbens dopamine signaling in socially isolated rats, Eur. J. Neurosci., 37, 10.1111/ejn.12113 Zhang, 2004, Neonatal isolation enhances maintenance but not reinstatement of cocaine self-administration in adult male rats, Psychopharmacology (Berl.), 177, 391, 10.1007/s00213-004-1963-y Zhu, 2010, [Effect of maternal deprivation on emotion and expression of dopamine transporter in adult rats], Zhong Nan Da Xue Xue Bao Yi Xue Ban, 35, 32