A set of computer programs to calculate agonist dissociation constants

Journal of Pharmacological Methods - Tập 22 - Trang 277-287 - 1989
Dorothy A. Jeffery1, Kathleen M. MacLeod1
1From the Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada

Tài liệu tham khảo

Cleland, 1967, The statistical analysis of enzyme kinetic data, Adv Enzymol, 29, 1 Furchgott, 1967, Comparison of dissociation constants and of relative efficacies of selected agonists acting on parasympathetic receptors, Ann NY Acad Sci, 144, 882, 10.1111/j.1749-6632.1967.tb53817.x Kenakin, 1989, Challenges for receptor theory as a tool for drug and drug receptor classification, Trends Pharm Sci, 10, 18, 10.1016/0165-6147(89)90102-8 MacKay, 1988, Continuous variation of agonist affinity constants, Trends Pharm Sci., 9, 156, 10.1016/0165-6147(88)90026-0 MacLeod, 1988, The mechanism of hypothermia-induced supersensitivity of guinea pig left atria to carbachol, Eur J Pharmacol, 158, 99, 10.1016/0014-2999(88)90258-0 McPherson, 1983, Analysis of dose-response curves and calculation of agonist dissociation constants using a weighted nonlinear curve-fitting program, J Pharmacol Methods, 10, 231, 10.1016/0160-5402(83)90017-7 Metzler, 1974, A package of computer programs for pharmacokinetic modeling, Biometrics, 30, 562 Parker, 1971, Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonists, J Pharmacol Exp Ther, 177, 1