Genome-wide association analysis identifies 20 loci that influence adult height

Nature Genetics - Tập 40 Số 5 - Trang 575-583 - 2008
Michael Inouye1, Hana Lango Allen1, Cecilia M. Lindgren2, Chris Wallace3, David M. Evans4, Massimo Mangino5, Rachel M. Freathy6, John R B Perry6, Mark M. Iles5, Alistair S. Hall7, Beverly M. Shields6, Inga Prokopenko2, Nilesh J. Samani8, Anna F. Dominiczak9, Toby Johnson10, Richard N. Bergman10, J. Beckmann10, Péter Vollenweider11, Dawn Waterworth12, Vincent Mooser12, Colin N. A. Palmer13, Willem H. Ouwehand14, Mark J. Caulfield3, Patricia B. Munroe3, Andrew T. Hattersley6, Mark I. McCarthy15, Timothy M. Frayling6
1Genetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, Magdalen Road, Exeter EX1 2LU, UK
2Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
3Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London, Queen Mary's School of Medicine, Charterhouse Square, London, EC1M 6BQ, UK
4Department of Social Medicine, Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, BS8 2PR, UK
5Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Groby Road, Leicester, LE3 9QP, UK
6Diabetes Genetics, Institute of Biomedical and Clinical Science, Peninsula Medical School, Barrack Road, Exeter, EX2 5DW, UK
7Leeds Institute of Genetics Health and Therapeutics, Faculty of Medicine and Health, University of Leeds, Leeds, LS2 9JT, UK
8Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK
9British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, 126 University Place, Glasgow, G12 8TA, UK
10Department of Medical Genetics, University of Lausanne, Lausanne, 1011, Switzerland
11Department of Medicine, Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, 1011, Switzerland
12Medical Genetics/Clinical Pharmacology and Discovery Medicine, GlaxoSmithKline, King of Prussia, 19406, Pennsylvania, USA
13Population Pharmacogenetics Group, Biomedical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK
14Department of Haematology, University of Cambridge, Long Road, Cambridge, CB2 2BT, UK
15Oxford Centre for Diabetes, Endocrinology and Medicine, University of Oxford, Churchill Hospital, Oxford, OX3 7LJ, UK

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