Quercetin enhances adiponectin secretion by a PPAR-γ independent mechanism

Ader, 2001, Interaction of quercetin glucosides with the intestinal sodium/glucose co-transporter (SGLT-1), Cancer Lett., 162, 175, 10.1016/S0304-3835(00)00645-5

Ader, 2000, Bioavailability and metabolism of the flavonol quercetin in the pig, Free Radic. Biol. Med., 28, 1056, 10.1016/S0891-5849(00)00195-7

Auger, 2005, Dietary wine phenolics catechin, quercetin, and resveratrol efficiently protect hypercholesterolemic hamsters against aortic fatty streak accumulation, J. Agric. Food Chem., 53, 2015, 10.1021/jf048177q

Bagi, 2004, PPAR{gamma} activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes, Am. J. Physiol. Heart Circ. Physiol., 286, H742, 10.1152/ajpheart.00718.2003

Benton, 2008, Rosiglitazone increases fatty acid oxidation and fatty acid translocase (FAT/CD36) but not carnitine palmitoyltransferase I in rat muscle mitochondria, J. Physiol.-Lond., 586, 1755, 10.1113/jphysiol.2007.146563

Boots, 2008, In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers, Nutrition, 24, 703, 10.1016/j.nut.2008.03.023

Cacho, 2008, Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague–Dawley rats, Am. J. Physiol.-Endocrinol. Metab., 295, E1269, 10.1152/ajpendo.90207.2008

Chien, 2005, Dietary flavonoids suppress adipogenesis in 3T3-L1 preadipocytes, J. Food Drug Anal., 13, 168

Cho, 2003, Quercetin suppresses proinflammatory cytokines production through MAP kinases and NF-kappaB pathway in lipopolysaccharide-stimulated macrophage, Mol. Cell. Biochem., 243, 153, 10.1023/A:1021624520740

Chopra, 2000, Nonalcoholic red wine extract and quercetin inhibit LDL oxidation without affecting plasma antioxidant vitamin and carotenoid concentrations, Clin. Chem., 46, 1162, 10.1093/clinchem/46.8.1162

Cnop, 2008, Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes, Biochem. Soc. Trans., 36, 348, 10.1042/BST0360348

Coskun, 2005, Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas, Pharmacol. Res., 51, 117, 10.1016/j.phrs.2004.06.002

da Silva, 2007, The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation, Diabetes, 56, 767, 10.2337/db06-1488

de Boer, 2005, Tissue distribution of quercetin in rats and pigs, J. Nutr., 135, 1718, 10.1093/jn/135.7.1718

Evans, 2002, Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes, Endocr. Rev., 23, 599, 10.1210/er.2001-0039

Formica, 1995, Review of the biology of quercetin and related bioflavonoids, Food Chem. Toxicol., 33, 1061, 10.1016/0278-6915(95)00077-1

Gabler, 2005, Consumption of raw brown onions variably modulate plasma lipid profile and lipoprotein oxidation in pigs fed a high-fat diet, J. Sci. Food Agric., 85, 154, 10.1002/jsfa.1976

Gonzalez-Segovia, 2008, Effect of the flavonoid quercetin on inflammation and lipid peroxidation induced by Helicobacter pylori in gastric mucosa of guinea pig, J. Gastroenterol., 43, 441, 10.1007/s00535-008-2184-7

Gopaul, 1995, Plasma 8-epi-PGF2 alpha levels are elevated in individuals with non-insulin dependent diabetes mellitus, FEBS Lett., 368, 225, 10.1016/0014-5793(95)00649-T

Guerre-Millo, 2008, Adiponectin: an update, Diabetes Metab., 34, 12, 10.1016/j.diabet.2007.08.002

Hamalainen, 2007, Mediat. Inflamm., 45673

Hansen, 2008, Nuclear receptors as drug targets in obesity, dyslipidemia and atherosclerosis, Curr. Opin. Invest. Drugs, 9, 247

Hertog, 1992, Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands, J. Agric. Food Chem., 40, 2379, 10.1021/jf00024a011

Kadowaki, 2005, Adiponectin and adiponectin receptors, Endocr. Rev., 26, 439, 10.1210/er.2005-0005

Kaku, 1999, Effect of dietary antioxidants on serum lipid contents and immunoglobulin productivity of lymphocytes in Sprague–Dawley rats, Biosci. Biotechnol. Biochem., 63, 575, 10.1271/bbb.63.575

Kamada, 2005, Attenuation of lipid peroxidation and hyperlipidemia by quercetin glucoside in the aorta of high cholesterol-fed rabbit, Free Radic. Res., 39, 185, 10.1080/10715760400019638

Kuppusamy, 1992, Effects of flavonoids on cyclic-amp phosphodiesterase and lipid mobilization in rat adipocytes, Biochem. Pharmacol., 44, 1307, 10.1016/0006-2952(92)90531-M

Larson-Meyer, 2006, Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects, Diabetes Care, 29, 1337, 10.2337/dc05-2565

Lesser, 2006, Oral bioavailability of the flavonol quercetin—a review, Curr. Top. Nutr. Res., 4, 239

Mahesh, 2004, Quercetin alleviates oxidative stress in streptozotocin-induced diabetic rats, Phytother. Res., 18, 123, 10.1002/ptr.1374

Manach, 2005, Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies, Am. J. Clin. Nutr., 81, 230S, 10.1093/ajcn/81.1.230S

Marinic, 2006, Interactions of quercetin and its lanthane complex with double stranded DNA/RNA and single stranded RNA: spectrophotometric sensing of poly G, J. Inorg. Biochem., 100, 288, 10.1016/j.jinorgbio.2005.11.013

Matthews, 1985, Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man, Diabetologia, 28, 412, 10.1007/BF00280883

Montuschi, 2004, Isoprostanes: markers and mediators of oxidative stress, FASEB J., 18, 1791, 10.1096/fj.04-2330rev

Morand, 1998, Plasma metabolites of quercetin and their antioxidant properties, Am. J. Physiol., 275, R212

Moskaug, 2005, Polyphenols and glutathione synthesis regulation, Am. J. Clin. Nutr., 81, 277S, 10.1093/ajcn/81.1.277S

Naumann, 1997, Die chemische Untersuchung von Futtermitteln

Perseghin, 2005, Muscle lipid metabolism in the metabolic syndrome, Curr. Opin. Lipidol., 16, 416, 10.1097/01.mol.0000174401.07056.56

Pfaffl, 2001, A new mathematical model for relative quantification in real-time RT-PCR, Nucl. Acids Res., 29, e45, 10.1093/nar/29.9.e45

Rivera, 2008, Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats, Obesity, 16, 2081, 10.1038/oby.2008.315

Robertson, 2004, beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes, Diabetes, 53, S119, 10.2337/diabetes.53.2007.S119

Sanders, 2001, Effects of quercetin on antioxidant defense in streptozotocin-induced diabetic rats, J. Biochem. Mol. Toxicol., 15, 143, 10.1002/jbt.11

Sharabi, 2007, Effect of PPAR-gamma agonist on adiponectin levels in the metabolic syndrome: lessons from the high fructose fed rat model, Am. J. Hypertens., 20, 206, 10.1016/j.amjhyper.2006.08.002

Shetty, 2004, Antidiabetic influence of quercetin in streptozotocin-induced diabetic rats, Nutr. Res., 24, 373, 10.1016/j.nutres.2003.11.010

Soobrattee, 2005, Phenolics as potential antioxidant therapeutic agents: mechanism and actions, Mutat. Res., 579, 200, 10.1016/j.mrfmmm.2005.03.023

Thuillier, 2002, Inhibition of peroxisome proliferator-activated receptor (PPAR)-mediated keratinocyte differentiation by lipoxygenase inhibitors, Biochem. J., 366, 901, 10.1042/bj20020377

Tilg, 2008, Inflammatory mechanisms in the regulation of insulin resistance, Mol. Med., 14, 222, 10.2119/2007-00119.Tilg

Ulich, 1991, Endotoxin-induced cytokine gene-expression in vivo. 3. Il-6 messenger-RNA and serum-protein expression and the in vivo hematologic effects of Il-6, J. Immunol., 146, 2316, 10.4049/jimmunol.146.7.2316

Urakawa, 2003, Oxidative stress is associated with adiposity and insulin resistance in men, J. Clin. Endocrinol. Metab., 88, 4673, 10.1210/jc.2003-030202

Vessal, 2003, Antidiabetic effects of quercetin in streptozocin-induced diabetic rats, Comp. Biochem. Physiol. C: Toxicol. Pharmacol., 135C, 357

Wein, 2009, Medium-chain fatty acids ameliorate insulin resistance caused by high-fat diets in rats, Diabetes Metab. Res. Rev., 25, 185, 10.1002/dmrr.925

Weldin, 2003, Quercetin, an over the-counter supplement, causes neuroblastoma-like elevation of plasma homovanillic acid, Pediatr. Dev. Pathol., 6, 547, 10.1007/s10024-003-5061-7

Wilding, 2006, Thiazolidinediones, insulin resistance and obesity: finding a balance, Int. J. Clin. Pract., 60, 1272, 10.1111/j.1742-1241.2006.01128.x

Yugarani, 1992, Effects of polyphenolic natural products on the lipid profiles of rats fed high fat diets, Lipids, 27, 181, 10.1007/BF02536175

Zern, 2003, Grape polyphenols decrease plasma triglycerides and cholesterol accumulation in the aorta of ovariectomized guinea pigs, J. Nutr., 133, 2268, 10.1093/jn/133.7.2268