Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells
Tài liệu tham khảo
Bender, 1991, Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae, Mol. Cell. Biol., 11, 1295
Bernards, 2006, shRNA libraries and their use in cancer genetics, Nat. Methods, 3, 701, 10.1038/nmeth921
Bild, 2006, Oncogenic pathway signatures in human cancers as a guide to targeted therapies, Nature, 439, 353, 10.1038/nature04296
Boehm, 2007, Integrative genomic approaches identify IKBKE as a breast cancer oncogene, Cell, 129, 1065, 10.1016/j.cell.2007.03.052
Bowen, 2005, RAS mutation in acute myeloid leukemia is associated with distinct cytogenetic subgroups but does not influence outcome in patients younger than 60 years, Blood, 106, 2113, 10.1182/blood-2005-03-0867
Chen, 1995, DLD-1 and HCT-15 cell lines derived separately from colorectal carcinomas have totally different chromosome changes but the same genetic origin, Cancer Genet. Cytogenet., 81, 103, 10.1016/0165-4608(94)00225-Z
Cragg, 2008, Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic, J. Clin. Invest., 118, 3651, 10.1172/JCI35437
Crowder, 2003, An unusual H-Ras mutant isolated from a human multiple myeloma line leads to transformation and factor-independent cell growth, Oncogene, 22, 649, 10.1038/sj.onc.1206180
DeBerardinis, 2008, The biology of cancer: metabolic reprogramming fuels cell growth and proliferation, Cell Metab., 7, 11, 10.1016/j.cmet.2007.10.002
Demunter, 2001, A novel N-ras mutation in malignant melanoma is associated with excellent prognosis, Cancer Res., 61, 4916
Demunter, 2001, Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma, J. Invest. Dermatol., 117, 1483, 10.1046/j.0022-202x.2001.01601.x
Djouder, 2007, S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling, Mol. Cell, 28, 28, 10.1016/j.molcel.2007.08.010
Downward, 2004, Use of RNA interference libraries to investigate oncogenic signalling in mammalian cells, Oncogene, 23, 8376, 10.1038/sj.onc.1208073
Faivre, 2006, Current development of mTOR inhibitors as anticancer agents, Nat. Rev. Drug Discov., 5, 671, 10.1038/nrd2062
Firestein, 2008, CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity, Nature, 455, 547, 10.1038/nature07179
Greenman, 2007, Patterns of somatic mutation in human cancer genomes, Nature, 446, 153, 10.1038/nature05610
Guertin, 2007, Defining the role of mTOR in cancer, Cancer Cell, 12, 9, 10.1016/j.ccr.2007.05.008
Harada, 2001, p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD, Proc. Natl. Acad. Sci. USA, 98, 9666, 10.1073/pnas.171301998
Hartwell, 1997, Integrating genetic approaches into the discovery of anticancer drugs, Science, 278, 1064, 10.1126/science.278.5340.1064
Jimeno, 2008, Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer, Cancer Res., 68, 2841, 10.1158/0008-5472.CAN-07-5200
Jones, 2008, Core signaling pathways in human pancreatic cancers revealed by global genomic analyses, Science, 321, 1801, 10.1126/science.1164368
Kaelin, 2005, The concept of synthetic lethality in the context of anticancer therapy, Nat. Rev. Cancer, 5, 689, 10.1038/nrc1691
Karnoub, 2008, Ras oncogenes: split personalities, Nat. Rev. Mol. Cell Biol., 9, 517, 10.1038/nrm2438
Kim, 2002, mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery, Cell, 110, 163, 10.1016/S0092-8674(02)00808-5
Koinuma, 2006, Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability, Oncogene, 25, 139, 10.1038/sj.onc.1209009
Ley, 2005, Regulatory phosphorylation of Bim: sorting out the ERK from the JNK, Cell Death Differ., 12, 1008, 10.1038/sj.cdd.4401688
Lin, 1998, Mutations of K-ras oncogene in human adrenal tumours in Taiwan, Br. J. Cancer, 77, 1060, 10.1038/bjc.1998.177
Lin, 2000, Decreased GTPase activity of K-ras mutants deriving from human functional adrenocortical tumours, Br. J. Cancer, 82, 1035, 10.1054/bjoc.1999.1039
Lucchesi, 1968, Synthetic lethality and semi-lethality among functionally related mutants of Drosophila melanogaster, Genetics, 59, 37, 10.1093/genetics/59.1.37
Moffat, 2006, A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen, Cell, 124, 1283, 10.1016/j.cell.2006.01.040
Mujica, 2001, A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3, Gene, 280, 175, 10.1016/S0378-1119(01)00780-6
Ngo, 2006, A loss-of-function RNA interference screen for molecular targets in cancer, Nature, 441, 106, 10.1038/nature04687
Parsons, 2008, An integrated genomic analysis of human glioblastoma multiforme, Science, 321, 1807, 10.1126/science.1164382
Pei, 1994, H-ras mutations in human pituitary carcinoma metastases, J. Clin. Endocrinol. Metab., 78, 842
Roberts, 2007, Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer, Oncogene, 26, 3291, 10.1038/sj.onc.1210422
Rocnik, 2006, Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD, Blood, 108, 1339, 10.1182/blood-2005-11-011429
Root, 2006, Genome-scale loss-of-function screening with a lentiviral RNAi library, Nat. Methods, 3, 715
Rottmann, 2005, A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function, Proc. Natl. Acad. Sci. USA, 102, 15195, 10.1073/pnas.0505114102
Ruvinsky, 2006, Ribosomal protein S6 phosphorylation: from protein synthesis to cell size, Trends Biochem. Sci., 31, 342, 10.1016/j.tibs.2006.04.003
Sarthy, 2007, Survivin depletion preferentially reduces the survival of activated K-Ras-transformed cells, Mol. Cancer Ther., 6, 269, 10.1158/1535-7163.MCT-06-0560
Sawyers, 2004, Targeted cancer therapy, Nature, 432, 294, 10.1038/nature03095
Schalm, 2005, Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation, J. Biol. Chem., 280, 11101, 10.1074/jbc.M413995200
Schlabach, 2008, Cancer proliferation gene discovery through functional genomics, Science, 319, 620, 10.1126/science.1149200
Schubbert, 2007, Hyperactive Ras in developmental disorders and cancer, Nat. Rev. Cancer, 7, 295, 10.1038/nrc2109
Shaffer, 2008, IRF4 addiction in multiple myeloma, Nature, 454, 226, 10.1038/nature07064
Shaw, 2006, Ras, PI(3)K and mTOR signalling controls tumour cell growth, Nature, 441, 424, 10.1038/nature04869
Shirasawa, 1993, Altered growth of human colon cancer cell lines disrupted at activated Ki-ras, Science, 260, 85, 10.1126/science.8465203
Silva, 2008, Profiling essential genes in human mammary cells by multiplex RNAi screening, Science, 319, 617, 10.1126/science.1149185
Simons, 2001, Establishment of a chemical synthetic lethality screen in cultured human cells, Genome Res., 11, 266, 10.1101/gr.154201
Smakman, 2006, KRAS(D13) Promotes apoptosis of human colorectal tumor cells by ReovirusT3D and oxaliplatin but not by tumor necrosis factor-related apoptosis-inducing ligand, Cancer Res., 66, 5403, 10.1158/0008-5472.CAN-05-4108
Solimini, 2007, Non-oncogene addiction and the stress phenotype of cancer cells, Cell, 130, 986, 10.1016/j.cell.2007.09.007
Solit, 2006, BRAF mutation predicts sensitivity to MEK inhibition, Nature, 439, 358, 10.1038/nature04304
Stockwell, 1999, High-throughput screening of small molecules in miniaturized mammalian cell-based assays involving post-translational modifications, Chem. Biol., 6, 71, 10.1016/S1074-5521(99)80004-0
Suzuki, 1990, Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products, Oncogene, 5, 1037
Torrance, 2001, Use of isogenic human cancer cells for high-throughput screening and drug discovery, Nat. Biotechnol., 19, 940, 10.1038/nbt1001-940
Turner, 2008, A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor, EMBO J., 27, 1368, 10.1038/emboj.2008.61
Varjosalo, 2008, Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling, Cell, 133, 537, 10.1016/j.cell.2008.02.047
Wang, 2006, Molecular mechanisms underlying the tumorigenesis of colorectal adenomas: correlation to activated K-ras oncogene, Oncol. Rep., 16, 1245
Westbrook, 2005, Dissecting cancer pathways and vulnerabilities with RNAi, Cold Spring Harb. Symp. Quant. Biol., 70, 435, 10.1101/sqb.2005.70.031
Whitehurst, 2007, Synthetic lethal screen identification of chemosensitizer loci in cancer cells, Nature, 446, 815, 10.1038/nature05697
Wood, 2007, The genomic landscapes of human breast and colorectal cancers, Science, 318, 1108, 10.1126/science.1145720
Yagoda, 2007, RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels, Nature, 447, 864, 10.1038/nature05859
Zha, 1996, Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L), Cell, 87, 619, 10.1016/S0092-8674(00)81382-3