Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota

Pharmacological Research - Tập 150 - Trang 104489 - 2019
Minna Wu1, Puze Li1, Yunying An1, Jie Ren1, Dong Yan1, Jiazeng Cui2, Duan Li1, Min Li1, Mingyong Wang3, Genshen Zhong3
1School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang 453003, Henan, China
2The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang 453003, Henan, China
3Henan Key Laboratory of Immunology and Targeted Therapy, Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, Xinxiang Medical University, Xinxiang 453003, Henan, China

Tài liệu tham khảo

Matsuoka, 2018, Evidence-based clinical practice guidelines for inflammatory bowel disease, J. Gastroenterol., 53, 305, 10.1007/s00535-018-1439-1 Eom, 2018, Current understanding of microbiota- and dietary-therapies for treating inflammatory bowel disease, J. Microbiol., 56, 189, 10.1007/s12275-018-8049-8 de Souza, 2017, Etiopathogenesis of inflammatory bowel disease: today and tomorrow, Curr. Opin. Gastroenterol., 33, 222, 10.1097/MOG.0000000000000364 Wang, 2016, Modified Pulsatilla decoction attenuates oxazolone-induced colitis in mice through suppression of inflammation and epithelial barrier disruption, Mol. Med. Rep., 14, 1173, 10.3892/mmr.2016.5358 Shen, 2018, Relationship between intestinal microbiota and ulcerative colitis: mechanisms and clinical application of probiotics and fecal microbiota transplantation, World J. Gastroenterol., 24, 5, 10.3748/wjg.v24.i1.5 Honda, 2016, The microbiota in adaptive immune homeostasis and disease, Nature, 535, 75, 10.1038/nature18848 Sun, 2018, Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis, Nat. Commun., 9, 3555, 10.1038/s41467-018-05901-2 Ananthakrishnan, 2018, Environmental triggers in IBD: a review of progress and evidence, Nat. Rev. Gastroenterol. Hepatol., 15, 39, 10.1038/nrgastro.2017.136 Celiberto, 2018, Inflammatory bowel disease and immunonutrition: novel therapeutic approaches through modulation of diet and the gut microbiome, Immunology, 155, 36, 10.1111/imm.12939 Kostic, 2014, The microbiome in inflammatory bowel disease: current status and the future ahead, Gastroenterology, 146, 1489, 10.1053/j.gastro.2014.02.009 Wei, 2018, Fecal microbiota transplantation ameliorates experimentally induced colitis in mice by upregulating AhR, Front. Microbiol., 9, 1921, 10.3389/fmicb.2018.01921 Paramsothy, 2017, Multidonor intensive fecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial, Lancet, 389, 1218, 10.1016/S0140-6736(17)30182-4 Lohr, 2006, Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease, J. Exp. Med., 203, 2785, 10.1084/jem.20061341 Wang, 2017, Improving the quality of ulcer healing in rats with ulcerative colitis, Evid. Complement. Alternat. Med., 2017 Cui, 2018, Berberine regulates Treg/Th17 balance to treat ulcerative colitis through modulating the gut microbiota in the colon, Front. Pharmacol., 9, 571, 10.3389/fphar.2018.00571 Akitake, 2010, Modulation of Th1/Th2 balance by infliximab rescues postoperative occurrence of small-intestinal inflammation associated with ulcerative colitis, Dig. Dis. Sci., 55, 1781, 10.1007/s10620-009-0910-5 Drolia, 2018, Listeria adhesion protein induces intestinal epithelial barrier dysfunction for bacterial translocation, Cell Host Microbe, 23, 470, 10.1016/j.chom.2018.03.004 Shan, 2013, Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals, Science, 342, 447, 10.1126/science.1237910 Turner JR, 2006, Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application, Am. J. Pathol., 169, 1901, 10.2353/ajpath.2006.060681 Rezk, 2002, The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids, Biochem. Biophys. Res. Commun., 295, 9, 10.1016/S0006-291X(02)00618-6 Wang, 2018, Phloretin reduces cell injury and inflammation mediated by Staphylococcus aureus via targeting sortase B and the molecular mechanism, Appl. Microbiol. Biotechnol., 102, 10665, 10.1007/s00253-018-9376-8 Park, 2007, Induction of apoptosis in HT-29 colon cancer cells by phloretin, J. Med. Food, 10, 581, 10.1089/jmf.2007.116 Zhang, 2019, The protective role of phloretin against dextran sulfate sodium-induced ulcerative colitis in mice, Food Funct., 10, 422, 10.1039/C8FO01699B Okayasu, 1990, A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice, Gastroenterology, 98, 694, 10.1016/0016-5085(90)90290-H Murthy, 1993, Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin, Dig. Dis. Sci., 38, 1722, 10.1007/BF01303184 Johansson, 2014, Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis, Gut, 63, 281, 10.1136/gutjnl-2012-303207 Bhatt, 2015, Novel evidence of microglial immune response in impairment of Dengue infection of CNS, Immunobiology., 220, 1170, 10.1016/j.imbio.2015.06.002 Dennis, 2013, Spatial uniformity of microbial diversity in a continuous bioelectrochemical system, Bioresour. Technol., 129, 599, 10.1016/j.biortech.2012.11.098 Edgar, 2013, UPARSE: highly accurate OTU sequences from microbial amplicon reads, Nat. Methods, 10, 996, 10.1038/nmeth.2604 Segata, 2011, Metagenomic biomarker discovery and explanation, Genome Biol., 12, R60, 10.1186/gb-2011-12-6-r60 Saito, 2012, A travel guide to Cytoscape plugins, Nat. Methods, 9, 1069, 10.1038/nmeth.2212 Langille, 2013, Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences, Nat. Biotechnol., 31, 814, 10.1038/nbt.2676 Man, 2015, Critical role for the DNA sensor AIM2 in stem cell proliferation and cancer, Cell, 162, 45, 10.1016/j.cell.2015.06.001 Ren, 2018, Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, Inflammation related Signaling Pathways and modulating the composition of the gut microbiota, J. Nutr. Biochem., 57, 67, 10.1016/j.jnutbio.2018.03.005 Neurath, 2014, Cytokines in inflammatory bowel disease, Nat. Rev. Immunol., 14, 329, 10.1038/nri3661 Schmitt, 2012, IL10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy, J. Immunol., 189, 5638, 10.4049/jimmunol.1200936 Talero, 2016, Expression patterns of sirtuin 1-AMPK-autophagy pathway in chronic colitis and inflammation-associated colon neoplasia in IL-10-deficient mice, Int. Immunopharmacol., 35, 248, 10.1016/j.intimp.2016.03.046 Ottman, 2017, Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function, PLoS One, 12, e0173004, 10.1371/journal.pone.0173004 Johansson, 2014, Mucus layers in inflammatory bowel disease, Inflamm. Bowel Dis., 20, 2124, 10.1097/MIB.0000000000000117 Wu, 2018, The dynamic changes of gut microbiota in Muc2 deficient mice, Int. J. Mol. Sci., 19, 2809, 10.3390/ijms19092809 Eisenstein, 2018, Gut reaction, Nature, 563, S34, 10.1038/d41586-018-07277-1 Qu, 2017, Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism, Pharmacol. Res., 121, 70, 10.1016/j.phrs.2017.04.017 Ford, 2013, Ulcerative colitis, BMJ, 346, f432, 10.1136/bmj.f432 Ueno, 2018, Th17 plasticity and its relevance to inflammatory bowel disease, J. Autoimmun., 87, 38, 10.1016/j.jaut.2017.12.004 Eastaff-Leung, 2010, Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease, J. Clin. Immunol., 30, 80, 10.1007/s10875-009-9345-1 Geremia, 2014, Innate and adaptive immunity in inflammatory bowel disease, Autoimmun. Rev., 13, 3, 10.1016/j.autrev.2013.06.004 Jonuleit, 2003, The regulatory T cell family: distinct subsets and their interrelations, J. Immunol., 171, 6323, 10.4049/jimmunol.171.12.6323 Miyake, 2015, Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to Clostridia XIVa and IV clusters, PLoS One, 10, 10.1371/journal.pone.0137429 Mazmanian, 2008, A microbial symbiosis factor prevents intestinal inflammatory disease, Nature, 453, 620, 10.1038/nature07008 Chaput, 2017, Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab, Ann. Oncol., 28, 1368, 10.1093/annonc/mdx108 Zhang, 2017, Chlorogenic acid ameliorates experimental colitis by promoting growth of Akkermansia in mice, Nutrients, 9, 677, 10.3390/nu9070677 Frank, 2007, Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases, Proc. Natl. Acad. Sci. U. S. A., 104, 13780, 10.1073/pnas.0706625104 Dziarski, 2016, Pglyrp-regulated gut microflora Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii enhance and Alistipes finegoldii attenuates colitis in mice, PLoS One, 11, 10.1371/journal.pone.0146162 Butera, 2018, Nod2 Deficiency in mice is associated with microbiota variation favouring the expansion of mucosal CD4+ LAP+ regulatory cells, Sci. Rep., 8, 14241, 10.1038/s41598-018-32583-z Yan, 2006, Probiotics as functional food in the treatment of diarrhea, Curr. Opin. Clin. Nutr. Metab. Care, 9, 717, 10.1097/01.mco.0000247477.02650.51 Mattar, 2002, Probiotics up-regulate MUC-2 mucin gene expression in a Caco-2 cell-culture model, Ped. Surg. Int., 18, 586, 10.1007/s00383-002-0855-7 Ashraf, 2014, Immune system stimulation by probiotic microorganisms, Crit. Rev. Food Sci. Nutr., 54, 938, 10.1080/10408398.2011.619671 Tang, 2015, Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillus-mediated regulatory T cell expansion in the intestine, Cell Host Microbe, 18, 183, 10.1016/j.chom.2015.07.003 Peng, 2019, Gut microbiota modulation and anti-inflammatory properties of anthocyanins from the fruits of Lycium ruthenicum Murray in dextran sodium sulfate-induced colitis in mice, Free Radic. Biol. Med., 136, 96, 10.1016/j.freeradbiomed.2019.04.005 Li, 2018, Initial gut microbiota structure affects sensitivity to DSS-induced colitis in a mouse model, Sci. China Life Sci., 61, 762, 10.1007/s11427-017-9097-0 Wang, 2018, VSL#3 can prevent ulcerative colitis-associated carcinogenesis in mice, World J. Gastroenterol., 24, 4254, 10.3748/wjg.v24.i37.4254 Lam, 2012, Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice, PLoS One, 7, e34233, 10.1371/journal.pone.0034233