Structural Modifications of Thalidomide Produce Analogs with Enhanced Tumor Necrosis Factor Inhibitory Activity
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Muller G., 1995, Novel inhibitors of tumor necrosis factor-α. Presented in part at the 210th American Chemical Society National Meeting
Schumacher H., 1965, Brit. J. Pharmacol., 25, 324
Georgopoulos A., 1990, Int. J. Exp. Clin. Chemother., 3, 141
D'Arcy P. F., 1994, Adverse Drug React. Toxicol. Rev., 13, 76
Crawford C. L, 1994, Adverse Drug React. Toxicol. Rev., 13, 192
Peterson D. L., 1995, Infection Clin. Infect. Dis., 20, 254
Vogelsang G. B., 1987, Trans. Proc., 2661
Klausner J., 1996, J. Acquired Immune Defic. Syndr., 11, 257
Crawford C. L., 1969, Lepr. Rev., 40, 128
Koch H. P, 1985, Prog. Med. Chem., 22, 242
D'amato R. J., 1994, Proc. Natl. Acad. Sci. U.S.A., 91, 4085
Madigan D., 1989, Aug. 23
Assay, Piscataway, NJ) density centrifugation. Cells (106 cells/mL) were cultured in RPMI (Gibco Laboratories
Thalidomide, All other IC50's were calculated by nonlinear regression analysis (variable slope) using Prism by GraphPad Software