Epigenetic Meta-Analysis Across Three Civilian Cohorts Identifies NRG1 and HGS as Blood-Based Biomarkers for Post-Traumatic Stress Disorder

Epigenomics - Tập 10 Số 12 - Trang 1585-1601 - 2018
Monica Uddin1,2, Andrew Ratanatharathorn3, Don Armstrong1, Pei Fen Kuan4, Allison E. Aiello5, Evelyn J. Bromet6, Sandro Galea7, Karestan C. Koenen8,9,10, Benjamin J. Luft11, Kerry J. Ressler12, Derek E. Wildman13,14, Caroline M. Nievergelt15,16, Alicia K. Smith17
1Carl R Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, IL 61801, USA
2Department of Psychology, University of Illinois Urbana-Champaign, 603 East Daniel St, Champaign, IL 61820, USA
3Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th St, NY 10032, USA
4Department of Applied Mathematics & Statistics, Stony Brook University, John S Toll Drive, Stony Brook, NY 11794, USA
5Department of Epidemiology, Gillings School of Public Health, University of North Carolina, 135 Dauer Drive, Chapel Hill, NC 27599, USA
6Department of Psychiatry, Stony Brook University School of Medicine, 101 Nicolls Rd, Stony Brook, NY 11794, USA
7Boston University, School of Public Health, 715 Albany St., Boston MA 02118 USA
8Department of Epidemiology, Harvard TH Chan School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
9Psychiatic & Neurodevelopmental Genetics Unit & Department of Psychiatry, Massachusetts General Hospital, Simches Research Building, 185 Cambridge Street, Boston, MA 02114, USA
10Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA 02142, USA
11Department of Medicine, Stony Brook University School of Medicine, 101 Nicolls Road, Stony Brook, NY 11794, USA
12Department of Psychiatry, McLean Hospital, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
13Carl R Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 West Gregory Drive, Urbana, IL 61801, USA Department of Molecular & Integrative Physiology, University of Illinois at Urbana-Champaign, 407 South Goodwin Avenue, Urbana, IL 61801, USA
14Department of Molecular & Integrative Physiology, University of Illinois at Urbana-Champaign, 407 South Goodwin Avenue, Urbana, IL 61801, USA
15Department of Psychiatry, University of California San Diego School of Medicine, 9500 Gilman Dr, La Jolla, CA 92093, USA VA Center of Excellence for Stress & Mental Health, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
16VA Center of Excellence for Stress & Mental Health, VA San Diego Healthcare System, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
17Department of Psychiatry & Behavioral Sciences & Department of Obstetrics & Gynecology, Emory University School of Medicine, 100 Woodruff Circle, Atlanta, GA 30322, USA

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