Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death

Chi Chen1, Rong Yu1, Edward D. Owuor1, Ah Ng Tony Kong1
1Center for Pharmaceutical Biotechnology (M/C 870), Department of Pharmaceutics and Pharmacodynamics College of Pharmacy, University of Illinois at Chicago, Chicago

Tóm tắt

Từ khóa


Tài liệu tham khảo

Adams, J. M. and Cory, S., The Bcl-2 protein family:arbiters of cell survival.Science, 281, 1322–1326 (1998).

Ahmad, N., Feyes, D. K., Nieminen, A. L., Agarwal, R. and Mukhtar, H., Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.J Natl Cancer Inst, 89, 1881–1886 (1997).

Bennett, M., Macdonald, K., Chan, S. W., Luzio, J. P., Simari, R. and Weissberg, P., Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis [see comments].Science, 282, 290–293 (1998).

Bu-Abbas, A., Clifford, M. N., Ioannides, C. and Walker, R., Stimulation of rat hepatic UDP-glucuronosyl transferase activity following treatment with green tea.Food Chem Toxicol, 33, 27–30 (1995).

Cobb, M. H. and Goldsmith, E. J., How MAP kinases are regulated.J Biol Chem, 270, 14843–14846 (1995).

Conney, A. H., Lu, Y., Lou, Y., Xie, J and Huang, M., Inhibitory effect of green and black tea on tumor growth.Proc Soc Exp Biol Med, 220, 229–233 (1999).

Gensler, H. L., Timmermann, B. N., Valcic, S., Wachter, G. A., Dorr, R., Dvorakova, K. and Alberts, D. S., Prevention of photocarcinogenesis by topical administration of pure epigallocatechin gallate isolated from green tea.Nutr Cancer, 26, 325–335 (1996).

Gupta, S., Ahmad, N, Nieminen, A. L. and Mukhtar, H., Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells.Toxicol Appl Pharmacol, 164, 82–90 (2000).

Khan, S. G., Katiyar, S. K., Agarwal, R. and Mukhtar, H., Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention.Cancer Res, 52, 4050–4052 (1992).

Kyriakis, J. M. and Avruch, J., Sounding the alarm: protein kinase cascades activated by stress and inflammation.J Biol Chem, 271, 24313–23316 (1996).

Laster, S. M., Wood, J. C. and Gooding, L. R., Tumor necrosis factor can induced both apoptic and necrotic forms of cell lysis.J. Immunol, 141, 2629–2634 (1988).

Lee, S. F., Liang, Y. C. and Lin, J. K., Inhibition of 1,2,4-benzenetriol-generated active oxygen species and induction of phase II enzymes by green tea polyphenols.Chem Biol Interact, 98, 283–301 (1995).

Li, N., Han, C. and Chen, J., Tea preparations protect against DMBA-induced oral carcinogenesis in hamsters.Nutr Cancer, 35, 73–79 (1999).

Marais, R. and Marshall, C. J., Control of the ERK MAP kinase cascade by Ras and Raf.Cancer Surv, 27, 101–125 (1996).

Mukhtar, H. and Ahmad, N., Green tea in chemoprevention of cancer.Toxicol Sci, 52, 111–117 (1999).

Nguyen, T., Huang, H. C. and Pickett, C. B., Transcriptional regulation of the antioxidant response element. Activation by Nrf2 and repression by Mafk.J. Biol Chem, 275, 15466–15473 (2000).

Paschka, A. G., Butler, R. and Young, C. Y., Induction of apoptosis in prostate cancer cell lines by the green tea component, (-)-epigallocatechin-3-gallate.Cancer Lett, 130, 1–7 (1998).

Steele, V. E., Bagheri, D., Balentine, D. A., Boone, C. W., Mehta, R., Morse, M. A., Sharma, S., Sigman, C. C., Stoner, G. D., Wargovich, M. J., Weisburger, J. H., Zhu, S. and Kelloff, G. J., Preclinical efficacy studies of green and black tea extracts.Proc Soc Exp Biol Med, 220, 210–212 (1999).

Thornberry, N. A. and Lazebnik, Y., Caspases: enemies within.Science, 281, 1312–1316 (1998).

Valcic, S., Timmermann, B. N., Alberts, D. S., Wachter, G. A., Krutzsch, M., Wymer, J. and Guillen, J. M., Inhibitory effect of six green tea catechins and caffeine on the growth of four selected human tumor cell lines.Anticancer Drugs, 7, 461–468 (1996).

Venugopal, R and Jaiswal, A. K.,Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD (P)H:quinone oxidoreductase1 gene.Proc Natl Acad Sci USA, 93, 14960–14965 (1996).

Wasserman, W. W. and Fahl, W. E., Functional antioxidant responsive elements.Proc Natl Acad Sci USA, 94, 5361–5366 (1997).

Weisburger, J. H., Tea and health: the underlying mechanisms.Proc Soc Exp Biol Med, 220, 271–275 (1999).

Xie, T., Belinsky, M., Xu, Y. and Jaiswal, A. K., ARE- and TRE-mediated regulation of gene expression. Response to xenobiotics and antioxidants.J Biol Chem, 270, 6894–6990 (1995).

Yang, G. Y., Liao, J., Kim, K., Yurkow, E. J. and Yang, C. S., Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.Carcinogenesis, 19, 611–616 (1998).

Yu, R., Mandlekar, S., Harvey, K. J., Ucker, D. S., and Kong, A. T., Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity.Cancer Res., 58, 402–508 (1998).

Yu, R., Chen, C., Mo, Y. Y., Hebbar, V., Owuor, E. D., Tan, T. H. and Kong, A. N., Activation of Mitogen-activated Protein Kinase Pathways Induces Antioxidant Response Element-mediated Gene Expression via Nrf2-dependent Mechanism.J Biol Chem, [in press] (2000a).

Yu, R., Jiao, J. J., Duh, J. L., Gudehithlu, K., Tan, T. H. and Kong, A. N. T., Activation of mitogen-activated protein kinases by green tea polyphenols: potential signaling pathways in the regulation of antioxidant-responsive element-mediated phase II enzyme gene expression.Carcinogenesis, 18, 451–456 (1997a).

Yu, R., Lei, W., Mandlekar, S., Weber, M. J., Der, C. J. Wu, J. and Kong, A. T., Role of a mitogen-activated protein kinase pathway in the induction of phase II detoxifying enzymes by chemicals.J Biol Chem, 274, 27545–27552 (1999).

Yu, R., Mandlekar, S. and Kong, A. T., Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c.Mol Pharmacol, 58, 431–437 (2000b).

Yu, R., Mandlekar, S., Lei, W., Fahl, W. E., Tan, T. H. and Kong, A. T., p38 mitogen-activated protein kinase negatively regulates the induction of phase II drug-meta-bolizing enzymes that detoxify carcinogens.J Biol Chem, 275, 2322–2327 (2000c).

Yu, R., Tan, T. H. and Kong, A. T., Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. The role of oxidative stress in the activation of mitogen-activated protein kinases by phenolic antioxidants.J Biol Chem, 272, 28962–28970 (1997b).

Zhao, B. L., Li, X. J., He, R. G., Cheng, S. J. and Xin, W. J., Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals.Cell Biophys, 14, 175–185 (1989).