Effect of oral intake of choline-stabilized orthosilicic acid on hair tensile strength and morphology in women with fine hair
Tóm tắt
The appearance of hair plays an important role in people’s overall physical appearance and self-perception. Silicon (Si) has been suggested to have a role in the formation of connective tissue and is present at 1–10 ppm in hair. Choline-stabilized orthosilicic acid (“ch-OSA”) is a bioavailable form of silicon which was found to improve skin microrelief and skin mechanical properties in women with photoaged skin. The effect of ch-OSA on hair was investigated in a randomized, double blind, placebo-controlled study. Forty-eight women with fine hair were given 10 mg Si/day in the form of ch-OSA beadlets (n = 24) or a placebo (n = 24), orally for 9 months. Hair morphology and tensile properties were evaluated before and after treatment. Urinary silicon concentration increased significantly in the ch-OSA supplemented group but not in the placebo group. The elastic gradient decreased in both groups but the change was significantly smaller in the ch-OSA group (−4.52%) compared to placebo group (−11.9%). Break load changed significantly in the placebo group (−10.8%) but not in the ch-OSA supplemented group (−2.20%). Break stress and elastic modulus decreased in both groups but the change was smaller in the ch-OSA group. The cross sectional area increased significantly after 9 months compared to baseline in ch-OSA supplemented subjects but not in the placebo group. The change in urinary silicon excretion was significantly correlated with the change in cross sectional area. Oral intake of ch-OSA had a positive effect on tensile strength including elasticity and break load and resulted in thicker hair.
Tài liệu tham khảo
Austin JH (1977) Silicon levels in human tissues. Nobel Symp 255–268
Barel A, Calomme M, Timchenko A, De Paepe K, Demeester N, Rogiers V, Clarys P, Vanden Berghe D (2005) Effect of oral intake of choline stabilized orthosilicic acid on skin, nails and hair in women with photodamaged skin. Arch Dermatol Res 297:147–153
Bell FI, Skinner R, Tucker IM, Leray Y, Lyons TE, Devine K, Pudney P, Oikawa T (2004) Biophysical and mechanical response of keratinous fibres to changes in temperature and humidity. J Cosmet Sci 55(Suppl):S19–S24
Blusztajn JK (1998) Choline, a vital amine. Science 281(5378):794–795
Braida D, Dubief C, Lang G (1994) Photoageing of hair fiber and photoprotection. Skin Pharmacol 7(1–2):73–77
Breathnach AS, Smith J (1968) Fine structure of the early hair germ and dermal papilla in the human foetus. J Anat 102(Pt3):511–526
Calomme MR, Vanden Berghe D (1997) Supplementation of calves with stabilized orthosilicic acid. Effect on the Si, Ca, Mg, and P concentrations in serum and the collagen concentration in skin and cartilage. Biol Trace Elem Res 56:153–165
Calomme M, Cos P, D’Haese P, Vingerhoets R, Lamberts L, De Broe M, Van Hoorebeke C, Vanden Berghe D (2000) Silicon absorption from stabilized orthosilicic acid and other supplements in healthy subjects. In: Roussel AM et al (eds) Trace elements in man and animals, vol 10. Plenum, New York, pp 1111–1114
Calomme MR, Wijnen P, Sindambiwe JB, Cos P, Mertens J, Geusens P, Vanden Berghe D (2002) Effect of choline stabilized orthosilicic acid on bone density in chicks. Calcif Tissue Int 70:292
Calomme M, Geusens P, Demeester N, Behets G, D’Haese P, Sindambiwe J, Van Hoof V, Vanden Berghe D (2006) Partial prevention of long-term femoral bone loss in aged ovariectomized rats supplemented with choline-stabilized orthosilicic acid. Calcif Tissue Int 78:227–232
Carlisle EM (1972) Silicon: an essential element for the chick. Science 178:619–621
Carlisle EM (1981) A silicon requirement for prolyl hydroxylase activity. Fed Proc 40:866
Carlisle EM (1981) Silicon: a requirement in bone formation independent of vitamin D1. Calcif Tissue Int 33:27–34
Coradin T, Livage J (2001) Effect of some amino acids and peptides on silicic acid polymerization. Colloids Surf B Biointerfaces 21:329–336
Coradin T, Lopez PJ (2003) Biogenic silica patterning: simple chemistry or subtle biology? Chembiochem 4(4):251–259
Courtois M, Loussouarn G, Hourseau S, Grollier JF (1996) Periodicity in the growth and shedding of hair. Br J Dermatol 134:47–54
Elliott K, Stephenson TJ, Messenger AG (1999) Differences in hair follicle dermal papilla volume are due to extracellular matrix volume and cell number: implications for the control of hair follicle size and androgen responses. J Invest Dermatol 113(6):873–877
Feughelman M, Watt IC (1966) Torsional properties of chemically modified wool fibers. Text Res J 36:849
Feughelman M (1971) The relation between structure and the mechanical properties of keratin fibers. Appl Polym Symp 18:757
Feughelman M (1982) The physical properties of alpha keratin fibers. J Soc Cosmet Chem 33:385
Fregert S (1958) Studies on silicon in tissues with special reference to skin. J Invest Dermatol 31(2):95–96
Gao T, Bedell A (2001) Ultraviolet damage on natural gray hair and its photoprotection. J Cosmet Sci 52(2):103–118
Jankovic SM, Jankovic SV (1998) The control of hair growth. Dermatol Online J 4(1):2
Jugdaohsingh R, Reffitt D, Oldham C, Davy JP, Fifield LK, Thompson RPH, Powell JJ (2000) Oligomeric but not monomeric silica prevents aluminum absorption in humans. Am J Clin Nutr 71:944–949
Pennington JA (1991) Silicon in food and diets. Food Addit Contam 8:97–118
Randall VA, Ebling FJG (1991) Seasonal changes in human hair growth. Br J Dermatol 124:146–151
Reffitt DM, Ogston N, Jugdaohsingh R, Cheung HFJ, Evans BAJ, Thompson RPH, Powell JJ, Hampson GN (2003) Orthosilicic acid (OSA) stimulates collagen type 1 synthesis and osteoblast differentation in human osteoblast-like cells in vitro. Bone 32:127–135
Roddick-Lanzilotta A, Kelly R (2004) Measurement and prevention of hair photoaging. J Cosmet Sci 55(Suppl):S113–S121
Schwarz K (1973) A bound form of silicon in glycosaminoglycans and polyuronides. Proc Natl Acad Sci USA 70(5):1608–1612
Shimoshima C et al (1988) Influences of protein malnutrition on amino acid composition, trace metal elements and tensile strength of rat hairs. J Nutr Sci Vitaminol 34(1):67–78
Smith BL (1993) Analysis of hair element levels by age, sex, race, and hair color. In: Anke M, Meissner D, Mills CF (eds) Trace elements in man and animals, TEMA 8. Kluwer, New York, pp 1091–1093
Sripanyakorn S, Jugdaohsingh R, Elliott H, Walker C, Mehta P, Shoukru S, Thompson RP, Powell JJ (2004) The silicon content of beer and its bioavailability in healthy volunteers. Br J Nutr 91(3):403–409
Swanbeck G, Nyren J, Juhlin L (1970) Mechanical properties of hairs from patients with different types of hair diseases. J Invest Dermatol 54(3):248–251
Teasdale D, Philippen H, Schlüter R, Meichelbeck H, Blankenburg G (1981) Querschnittsparameter von Humanhaaren, Teil 1: Grundlagen und Meβtechniken. Ärzt Kosm 11:161–170
Van Dyck K, Van Cauwenberghe R, Robberecht H, Deelstra H (1999) Bioavailability of silicon from food and food supplements. Fresenius J Anal Chem 363:541–544
Wickett RR (1995) Measuring the mechanical strength of hair. In: Serup J, Jemec BE (eds) Handbook of non-invasive methods and the skin. CRC, Boca Raton, pp 535–541
Wickett RR (2000) The chemistry and physics of hair. In: Schlossman ML (ed) The chemistry and manufacture of cosmetics, vol 1, basic science. Allured Publishing, Carol Stream, pp 255–284
Zeisel SH (1990) Choline deficiency. J Nutr Biochem 1:332–349
Zviak C, Bouillon C (1986) Hair treatment and hair care products. In: Zviak C (ed) The science of hair care. Marcel Dekker, New York, p 142