Lessons learned from the International Renal Cell Carcinoma-Venous Thrombus Consortium (IRCC-VTC)

Current Urology Reports - Tập 15 - Trang 1-9 - 2014
Juan I. Martínez-Salamanca1, Estefania Linares1, Javier González2, Roberto Bertini3, Joaquín A. Carballido1, Thomas Chromecki4, Gaetano Ciancio5, Sia Daneshmand6, Christopher P. Evans7, Paolo Gontero8, Axel Haferkamp9, Markus Hohenfellner10, William C. Huang11, Theresa M. Koppie12, Viraj A. Master13, Rayan Matloob3, James M. McKiernan14, Carrie M. Mlynarczyk14, Francesco Montorsi3, Hao G. Nguyen7, Giacomo Novara15, Sascha Pahernik10, Juan Palou16, Raj S. Pruthi17, Krishna Ramaswamy11, Oscar Rodriguez Faba17, Paul Russo18, Shahrokh F. Shariat19, Martin Spahn20, Carlo Terrone21, Derya Tilki7, Daniel Vergho21, Eric M. Wallen22, Evanguelos Xylinas22, Richard Zigeuner4, John A. Libertino21
1Department of Urology, Hospital Universitario Puerta de Hierro-Majadahonda, Universidad Autónoma de Madrid, Majadahonda, Spain
2Department of Urology, Hospital Central de la Cruz Roja San José y Santa Adela, Madrid, Spain
3Department of Urology, Hospital San Raffaele, University Vita-Salute, Milano, Italy
4Department of Urology, Medical University of Graz, Graz, Austria
5Miami Transplant Institute, University of Miami, Miami, USA
6USC Norris Comprehensive Cancer Center, Los Angeles, USA
7Department of Urology, UC Davis Medical Center, Sacramento, USA
8Department of Urology, A.O.U. San Giovanni Battista, University of Turin, Turin, Italy
9Department of Urology, University of Frankfurt, Frankfurt, Germany
10Department of Urology, University of Heidelberg, Heidelberg, Germany
11Department of Urology, New York University School of Medicine, New York, USA
12Department of Urology, Oregon Health & Science University, Portland, USA
13Department of Urology, Emory University, Atlanta, USA
14Department of Urology, Columbia University College of Physicians and Surgeons, New York, USA
15University of Padua, Padua, Italy
16Department of Urology, Fundació Puigvert, Barcelona, Spain
17Department of Urology, UNC at Chapel Hill, Chapel Hill, USA
18Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, USA
19University of Würzburg, Würzburg, Germany
20Division of Urology, Maggiore della Carita’ Hospital, University of Eastern Piedmont, Novara, Italy
21Department of Urology, Lahey Clinic, Burlington, USA
22Department of Urology, Weill Cornell Medical, Center, USA

Tóm tắt

Renal cell carcinoma (RCC) extension into the renal vein or the inferior vena cava occurs in 4 %–10 % of all kidney cancer cases. This entity shows a wide range of different clinical and surgical scenarios, making natural history and oncological outcomes variable and poorly characterized. Infrequency and variability make it necessary to share the experience from different institutions to properly analyze surgical outcomes in this setting. The International Renal Cell Carcinoma–Venous Tumor Thrombus Consortium was created to answer the questions generated by competing results from different retrospective studies in RCC with venous extension on current controversial topics. The aim of this article is to summarize the experience gained from the analysis of the world's largest cohort of patients in this unique setting to date.

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