Hunter, 1995, Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling, Cell, 80, 225, 10.1016/0092-8674(95)90405-0
Franklin, 2000, Kinases: positive and negative regulators of apoptosis, Leukemia, 14, 2019, 10.1038/sj.leu.2401967
Hunter, 2000, Signaling—2000 and beyond, Cell, 100, 113, 10.1016/S0092-8674(00)81688-8
Garrett, 1999, Discovering novel chemotherapeutic drugs for the third millennium, Eur J Cancer, 35, 2010, 10.1016/S0959-8049(99)00280-4
Bhagwat, 1999, Gene-regulating protein kinases as important anti-inflammatory targets, Drug Discov Today, 4, 472, 10.1016/S1359-6446(99)01402-6
Bolen, 1997, Leukocyte protein tyrosine kinases: potential targets for drug discovery, Annu Rev Immunol, 15, 371, 10.1146/annurev.immunol.15.1.371
Fletcher, 2001, Approval heralds new generation of kinase inhibitors?, Nat Biotechnol, 19, 599, 10.1038/90172
McDonald, 1999, A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: highthroughput screening and identification of selective enzyme inhibitors, Anal Biochem, 268, 318, 10.1006/abio.1998.3030
Beveridge, 2000, Detection of p56(lck) kinase activity using scintillation proximity assay in 384-well format and imaging proximity assay in 384- and 1536-well format, J Biomol Screen, 5, 205, 10.1177/108705710000500403
Schaefer, 1998, Detection of protein tyrosine kinase activity using a high-capacity streptavidin-coated membrane and optimized biotinylated peptide substrates, Anal Biochem, 261, 100, 10.1006/abio.1998.2716
Mallon, 2001, An enzyme-linked immunosorbent assay for the Raf/MEK1/MAPK signaling cascade, Anal Biochem, 294, 48, 10.1006/abio.2001.5151
Stenroos, 1998, Homogeneous time-resolved IL-2-IL-2R alpha assay using fluorescence resonance energy transfer, Cytokine, 10, 495, 10.1006/cyto.1997.0321
Parker, 2000, Development of high throughput screening assays using fluorescence polarization: nuclear receptor-ligand binding and kinase/phosphatase assays, J Biomol Screen, 5, 77, 10.1177/108705710000500204
Nakayama, 1999, An immunoassay for assessment of receptor tyrosine kinase autophosphorylation, J Immunol Methods, 225, 67, 10.1016/S0022-1759(99)00029-0
Seethala, 1997, A homogeneous, fluorescence polarization assay for src-family tyrosine kinases, Anal Biochem, 253, 210, 10.1006/abio.1997.2365
Seethala, 1998, A fluorescence polarization competition immunoassay for tyrosine kinases, Anal Biochem, 255, 257, 10.1006/abio.1997.2455
Wu, 2000, Identification of a high-affinity antiphosphoserine antibody for the development of a homogeneous fluorescence polarization assay of protein kinase C, J Biomol Screen, 5, 23, 10.1177/108705710000500106
Coffin, 2000, Detection of phosphopeptides by fluorescence polarization in the presence of cationic polyamino acids: application to kinase assays, Anal Biochem, 278, 206, 10.1006/abio.1999.4438
Huang, 2002, A fluorescence polarization assay for cyclic nucleotide phosphodiesterases, J Biomol Screen, 7, 215, 10.1177/108705710200700305
Webster, 1993, Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum, Mol Cell Biol, 13, 2031
Waldegger, 1997, Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume, Proc Natl Acad Sci USA, 94, 4440, 10.1073/pnas.94.9.4440
Park, 1999, Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinasestimulated signaling pathway, EMBO J, 18, 3024, 10.1093/emboj/18.11.3024
Perrotti, 2001, Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin, J Biol Chem, 276, 9406, 10.1074/jbc.M007052200
Zhang, 2001, Serumand glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf, J Biol Chem, 276, 31620, 10.1074/jbc.M102808200
Mikosz, 2001, Glucocorticoid receptor-mediated protection from apoptosis is associated with induction of the serine/threonine survival kinase gene, sgk-1, J Biol Chem, 276, 16649, 10.1074/jbc.M010842200
Chan, 1999, AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositidedependent phosphorylation, Annu Rev Biochem, 68, 965, 10.1146/annurev.biochem.68.1.965
Page, 2000, Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis, Anticancer Res, 20, 407
Ringel, 2001, Overexpression and overactivation of Akt in thyroid carcinoma, Cancer Res, 61, 6105
Brazil, 2001, Ten years of protein kinase B signalling: a hard Akt to follow, Trends Biochem Sci, 26, 657, 10.1016/S0968-0004(01)01958-2
Martin-Blanco, 2000, p38 MAPK signalling cascades: ancient roles and new functions, Bioessays, 22, 637, 10.1002/1521-1878(200007)22:7<637::AID-BIES6>3.0.CO;2-E
Lee, 2000, Inhibition of p38 MAP kinase as a therapeutic strategy, Immunopharmacology, 47, 185, 10.1016/S0162-3109(00)00206-X
Tessier-Lavigne, 1995, Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps, Cell, 82, 345, 10.1016/0092-8674(95)90421-2
Wang, 1997, Eph family transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth, Neuron, 18, 383, 10.1016/S0896-6273(00)81240-4
Adams, 1999, Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis, Genes Dev, 13, 295, 10.1101/gad.13.3.295
Wang, 1998, Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4, Cell, 93, 741, 10.1016/S0092-8674(00)81436-1
Vogt, 1998, Overexpression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas, Clin Cancer Res, 4, 791
Tang, 1999, Coexpression of transcripts encoding EPHB receptor protein tyrosine kinases and their ephrin-B ligands in human small cell lung carcinoma, Clin Cancer Res, 5, 455
Zhang, 1999, A simple statistical parameter for use in evaluation and validation of high throughput screening assays, J Biomol Screen, 4, 67, 10.1177/108705719900400206
Verme, 1989, Effects of staurosporine on protein kinase C and amylase secretion from pancreatic acini, Am J Physiol, 257, G548
Spacey, 1990, Selectivity of protein kinase inhibitors in human intact platelets, Cell Signal, 2, 329, 10.1016/0898-6568(90)90062-F
Davies, 2000, Specificity and mechanism of action of some commonly used protein kinase inhibitors, Biochem J, 351, 95, 10.1042/bj3510095
Hayess, 1997, Effect of protein kinase inhibitors on activity of mammalian small heat-shock protein (HSP25) kinase, Biochem Pharmacol, 53, 1239, 10.1016/S0006-2952(96)00877-5
Saklatvala, 1996, Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue, J Biol Chem, 271, 6586, 10.1074/jbc.271.12.6586
Owicki, 2000, Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer, J Biomol Screen, 5, 297, 10.1177/108705710000500501