Local Recurrence After Complete Clinical Response and Watch and Wait in Rectal Cancer After Neoadjuvant Chemoradiation: Impact of Salvage Therapy on Local Disease Control

Sanghera, 2008, Chemoradiotherapy for rectal cancer: An updated analysis of factors affecting pathological response, Clin Oncol (R Coll Radiol), 20, 176, 10.1016/j.clon.2007.11.013 Maas, 2010, Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: A pooled analysis of individual patient data, Lancet Oncol, 11, 835, 10.1016/S1470-2045(10)70172-8 Smith, 2010, Rectum-conserving surgery in the era of chemoradiotherapy, Br J Surg, 97, 1752, 10.1002/bjs.7251 Hughes, 2006, Can pathological complete response in the primary tumour following pre-operative pelvic chemoradiotherapy for T3-T4 rectal cancer predict for sterilisation of pelvic lymph nodes, a low risk of local recurrence and the appropriateness of local excision?, Int J Colorectal Dis, 21, 11, 10.1007/s00384-005-0749-y Garcia-Aguilar, 2012, A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: Preliminary results of the ACOSOG Z6041 trial, Ann Surg Oncol, 19, 384, 10.1245/s10434-011-1933-7 Marks, 2009, Transanal endoscopic microsurgery for the treatment of rectal cancer: Comparison of wound complication rates with and without neoadjuvant radiation therapy, Surg Endosc, 23, 1081, 10.1007/s00464-009-0326-5 Perez, 2011, Transanal endoscopic microsurgery for residual rectal cancer after neoadjuvant chemoradiation therapy is associated with significant immediate pain and hospital readmission rates, Dis Colon Rectum, 54, 545, 10.1007/DCR.0b013e3182083b84 Habr-Gama, 2004, Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: Long-term results, Ann Surg, 240, 711, 10.1097/01.sla.0000141194.27992.32 Maas, 2011, Wait-and-see policy for clinical complete responders after chemoradiation for rectal cancer, J Clin Oncol, 29, 4633, 10.1200/JCO.2011.37.7176 Habr-Gama, 2010, Complete clinical response after neoadjuvant chemoradiation therapy for distal rectal cancer: Characterization of clinical and endoscopic findings for standardization, Dis Colon Rectum, 53, 1692, 10.1007/DCR.0b013e3181f42b89 Habr-Gama, 2006, Patterns of failure and survival for nonoperative treatment of stage c0 distal rectal cancer following neoadjuvant chemoradiation therapy, J Gastrointest Surg, 10, 1319, 10.1016/j.gassur.2006.09.005 Habr-Gama, 2009, Increasing the rates of complete response to neoadjuvant chemoradiotherapy for distal rectal cancer: Results of a prospective study using additional chemotherapy during the resting period, Dis Colon Rectum, 52, 1927, 10.1007/DCR.0b013e3181ba14ed Mignanelli, 2010, Downstaging after chemoradiotherapy for locally advanced rectal cancer: Is there more (tumor) than meets the eye?, Dis Colon Rectum, 53, 251, 10.1007/DCR.0b013e3181bcd3cc Bujko, 2005, Prediction of mesorectal nodal metastases after chemoradiation for rectal cancer: Results of a randomised trial: Implication for subsequent local excision, Radiother Oncol, 76, 234, 10.1016/j.radonc.2005.04.004 Kim, 2006, Is T classification still correlated with lymph node status after preoperative chemoradiotherapy for rectal cancer?, Cancer, 106, 1694, 10.1002/cncr.21794 Habr-Gama, 2005, Long-term results of preoperative chemoradiation for distal rectal cancer correlation between final stage and survival, J Gastrointest Surg, 9, 90, 10.1016/j.gassur.2004.10.010 Lezoche, 1996, Is transanal endoscopic microsurgery (TEM) a valid treatment for rectal tumors?, Surg Endosc, 10, 736, 10.1007/BF00193047