Not all viruses are bad guys: the case for reovirus in cancer therapy

Drug Discovery Today - Tập 10 - Trang 847-855 - 2005
Kara L. Norman1, Patrick W.K. Lee2
1Cancer Biology Research Group, and Department of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada
2Current address: Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University. Halifax, Nova Scotia, B3H 1X5, Canada

Tài liệu tham khảo

Jemal, 2004, Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival, Cancer, 101, 3, 10.1002/cncr.20288 Cobleigh, 1999, Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease, J. Clin. Oncol., 17, 2639, 10.1200/JCO.1999.17.9.2639 Powles, 2002, Anti-oestrogenic prevention of breast cancer-the make or break point, Nat. Rev. Cancer, 2, 787, 10.1038/nrc908 Kaelin, 2004, Gleevec: prototype or outlier?, Sci. STKE 2004, pe12 Bischoff, 1996, An adenovirus mutant that replicates selectively in p53-deficient human tumor cells, Science, 274, 373, 10.1126/science.274.5286.373 Martuza, 1991, Experimental therapy of human glioma by means of a genetically engineered virus mutant, Science, 252, 854, 10.1126/science.1851332 Coffey, 1998, Reovirus therapy of tumors with activated Ras pathway, Science, 282, 1332, 10.1126/science.282.5392.1332 Strong, 1998, The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus, EMBO J., 17, 3351, 10.1093/emboj/17.12.3351 Minuk, 1985, The prevalence of antibodies to reovirus type 3 in adults with idiopathic cholestatic liver disease, J. Med. Virol., 16, 55, 10.1002/jmv.1890160108 Norman, 2002, Reovirus oncolysis of human breast cancer, Hum. Gene Ther., 13, 641, 10.1089/10430340252837233 Hirasawa, 2002, Oncolytic reovirus against ovarian and colon cancer, Cancer Res., 62, 1696 Yang, 2003, Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma, Cancer Res., 63, 3162 Wilcox, 2001, Reovirus as an oncolytic agent against experimental human malignant gliomas, J. Natl. Cancer Inst., 93, 903, 10.1093/jnci/93.12.903 Alain, 2002, Reovirus therapy of lymphoid malignancies, Blood, 100, 4146, 10.1182/blood-2002-02-0503 Thirukkumaran, 2003, Reovirus oncolysis as a novel purging strategy for autologous stem cell transplantation, Blood, 102, 377, 10.1182/blood-2002-08-2508 Etoh, 2003, Oncolytic viral therapy for human pancreatic cancer cells by reovirus, Clin. Cancer Res., 9, 1218 Kilani, 2003, Selective reovirus killing of bladder cancer in a co-culture spheroid model, Virus Res., 93, 1, 10.1016/S0168-1702(03)00045-5 Sabin, 1959, Reoviruses: A new group of respiratory and enteric viruses formerly classified as ECHO type 10 is described, Science, 130, 1387, 10.1126/science.130.3386.1387 Stanley, 1953, Studies on the pathogenesis of a hitherto undescribed virus (hepato-encephalomyelitis) producing unusual symptoms in suckling mice, Aust. J. Exp. Biol. Med. Sci., 31, 147, 10.1038/icb.1953.18 Wilson, 1994, Association of the reovirus S1 gene with serotype 3-induced biliary atresia in mice, J. Virol., 68, 6458, 10.1128/JVI.68.10.6458-6465.1994 Barton, 2003, Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease, J. Clin. Invest., 111, 1823, 10.1172/JCI16303 Derrien, 2003, The M2 gene segment is involved in the capacity of reovirus type 3Abney to induce the oily fur syndrome in neonatal mice, a S1 gene segment-associated phenotype, Virology, 305, 25, 10.1006/viro.2002.1723 Morecki, 1982, Biliary atresia and reovirus type 3 infection, N. Engl. J. Med., 307, 481, 10.1056/NEJM198208193070806 Glaser, 1984, Role of reovirus type 3 in persistent infantile cholestasis, J. Pediatr., 105, 912, 10.1016/S0022-3476(84)80076-1 Brown, 1990, Lack of conformation of the association of reovirus 3 and biliary atresia: methodological differences, Hepatology, 12, 1254, 10.1002/hep.1840120533 Brown, 1988, Lack of correlation between infection with reovirus 3 and extrahepatic biliary atresia or neonatal hepatitis, J. Pediatr., 113, 670, 10.1016/S0022-3476(88)80376-7 Dussaix, 1984, Biliary atresia and reovirus type 3 infection, N. Engl. J. Med., 310, 658, 10.1056/NEJM198403083101016 Tyler, 1998, Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts, Hepatology, 27, 1475, 10.1002/hep.510270603 Steele, 1995, Reovirus 3 not detected by reverse transcriptase-mediated polymerase chain reaction analysis of preserved tissue from infants with cholestatic liver disease, Hepatology, 21, 697 Saito, 2004, Lack of evidence for reovirus infection in tissues from patients with biliary atresia and congenital dilatation of the bile duct, J. Hepatol., 40, 203, 10.1016/j.jhep.2003.10.025 Rosen, 1963, Reovirus infections in human volunteers, Am. J. Hyg., 77, 29 Hirasawa, 2003, Systemic reovirus therapy of metastatic cancer in immune-competent mice, Cancer Res., 63, 348 Yang, 2004, Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer, Gene Ther., 11, 1579, 10.1038/sj.gt.3302319 Hashiro, 1977, The preferential cytotoxicity of reovirus for certain transformed cell lines, Arch. Virol., 54, 307, 10.1007/BF01314776 Duncan, 1978, Differential sensitivity of normal and transformed human cells to reovirus infection, J. Virol., 28, 444, 10.1128/JVI.28.2.444-449.1978 Strong, 1993, Evidence that the epidermal growth factor receptor on host cells confers reovirus infection efficiency, Virology, 197, 405, 10.1006/viro.1993.1602 Tang, 1993, Recognition of the epidermal growth factor receptor by reovirus, Virology, 197, 412, 10.1006/viro.1993.1603 Strong, 1996, The v-erbB oncogene confers enhanced cellular susceptibility to reovirus infection, J. Virol., 70, 612, 10.1128/JVI.70.1.612-616.1996 Takai, 2001, Small GTP-binding proteins, Physiol. Rev., 81, 153, 10.1152/physrev.2001.81.1.153 Campbell, 1998, Increasing complexity of Ras signaling, Oncogene, 17, 1395, 10.1038/sj.onc.1202174 Bos, 1989, ras oncogenes in human cancer: a review, Cancer Res., 49, 4682 Guha, 1997, Proliferation of human malignant astrocytomas is dependent on Ras activation, Oncogene, 15, 2755, 10.1038/sj.onc.1201455 Norman, 2004, Reovirus oncolysis: the Ras/RalGEF/p38 pathway dictates host cell permissiveness to reovirus infection, Proc. Natl. Acad. Sci. U. S. A., 101, 11099, 10.1073/pnas.0404310101 Louis, 2002, Focus on central nervous system neoplasia, Cancer Cell, 1, 125, 10.1016/S1535-6108(02)00040-5 Slamon, 1989, Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer, Science, 244, 707, 10.1126/science.2470152 Dankort, 1997, Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation, Mol. Cell. Biol., 17, 5410, 10.1128/MCB.17.9.5410 deFazio, 2000, Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines, Int. J. Cancer, 87, 487, 10.1002/1097-0215(20000815)87:4<487::AID-IJC5>3.0.CO;2-J Hanel, 2004, A novel intravesical therapy for superficial bladder cancer in an orthotopic model: oncolytic reovirus therapy, J. Urol., 172, 2018, 10.1097/01.ju.0000142657.62689.f6 McLaughlin, 2002, Progress in the treatment of indolent lymphomas, Oncologist, 7, 217, 10.1634/theoncologist.7-3-217 Elenitoba-Johnson, 2003, Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy, Proc. Natl. Acad. Sci. U. S. A., 100, 7259, 10.1073/pnas.1137463100 Hii, 2004, Loss of PKR activity in chronic lymphocytic leukemia, Int. J. Cancer, 109, 329, 10.1002/ijc.11714 Rill, 1994, Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells, Blood, 84, 380, 10.1182/blood.V84.2.380.380 Morris, D.G. et al. (2002) A phase I clinical trial evaluating intralesional Reolysin (reovirus) in histilogically confirmed malignancies. American Society of Clinical Oncology Annual Meeting. Yang, 2004, Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates, Clin. Cancer Res., 10, 8561, 10.1158/1078-0432.CCR-04-0940 Roner, 2001, Reovirus reverse genetics: Incorporation of the CAT gene into the reovirus genome, Proc. Natl. Acad. Sci. U. S. A., 98, 8036, 10.1073/pnas.131203198 Khuri, 2000, a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer, Nat. Med., 6, 879, 10.1038/78638 Reid, 2002, Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints, Cancer Res., 62, 6070 Organ, 2004, Discovery of mammalian genes that participate in virus infection, BMC Cell Biol., 5, 41, 10.1186/1471-2121-5-41 Feig, 2003, Ral-GTPases: approaching their 15 minutes of fame, Trends Cell Biol., 13, 419, 10.1016/S0962-8924(03)00152-1 Nibert, 2001, Reoviruses and Their Replication Paul, 1989, The alpha-anomeric form of sialic acid is the minimal receptor determinant recognized by reovirus, Virology, 172, 382, 10.1016/0042-6822(89)90146-3 Barton, 2001, Junction adhesion molecule is a receptor for reovirus, Cell, 104, 441, 10.1016/S0092-8674(01)00231-8 Chandran, 2003, Animal cell invasion by a large nonenveloped virus: reovirus delivers the goods, Trends Microbiol., 11, 374, 10.1016/S0966-842X(03)00178-1 Reinisch, 2000, Structure of the reovirus core at 3.6 A resolution, Nature, 404, 960, 10.1038/35010041 Luongo, 1998, Binding site for S-adenosyl-L-methionine in a central region of mammalian reovirus lambda2 protein, Evidence for activities in mRNA cap methylation. J. Biol. Chem., 273, 23773 Poggioli, 2001, Reovirus-induced sigma's-dependent G(2)/M phase cell cycle arrest is associated with inhibition of p34(cdc2), J. Virol., 75, 7429, 10.1128/JVI.75.16.7429-7434.2001 Golden, 2002, Addition of exogenous protease facilitates reovirus infection in many restrictive cells, J. Virol., 76, 7430, 10.1128/JVI.76.15.7430-7443.2002