Artematrolide A inhibited cervical cancer cell proliferation via ROS/ERK/mTOR pathway and metabolic shift

Phytomedicine - Tập 91 - Trang 153707 - 2021
Xin-Tian Zhang1,2, Jing Hu1, Li-Hua Su1,2, Chang-An Geng1, Ji-Jun Chen1,2
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, People's Republic of China
2University of Chinese Academy of Sciences, Beijing 100049, People’s Republic of China

Tài liệu tham khảo

Cagnol, 2010, ERK and cell death: Mechanisms of ERK-induced cell death – apoptosis, autophagy and senescence, FEBS journal, 10.1111/j.1742-4658.2009.07366.x Cohausz, 2009, Role of PARP-1 and PARP-2 in the expression of apoptosis-regulating genes in HeLa cells, Cell Biol. Toxicol., 25, 379, 10.1007/s10565-008-9092-8 Donnino, 2016, Randomized, double-blind, placebo-controlled trial of thiamine as a metabolic resuscitator in septic shock: a pilot study, Crit. Care Med., 44, 360, 10.1097/CCM.0000000000001572 Edlich, 2018, BCL-2 proteins and apoptosis: recent insights and unknowns, Biochem. Biophys. Res. Commun., 500, 26, 10.1016/j.bbrc.2017.06.190 Fang, 2018, A new xanthatin analogue 1 β -hydroxyl-5 α -chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma, Biochimie, 152, 43, 10.1016/j.biochi.2018.06.018 Guo, 2020, ERK/MAPK signalling pathway and tumorigenesis (review), Exp. Ther. Med, 19, 1997 Jeong, 2008, Low concentration of 3-carene stimulates the differentiation of mouse osteoblastic MC3T3- E1 subclone 4 cells, Phytother. Res., 22, 18, 10.1002/ptr.2247 Koh, 2019, Cervical cancer, version 3.2019, J. Natl. Compr. Canc. Netw., 17, 64, 10.6004/jnccn.2019.0001 Koppenol, 2011, Otto Warburg's contributions to current concepts of cancer metabolism, Nat. Rev. Cancer, 11, 325, 10.1038/nrc3038 Ma, 2020, Natural disesquiterpenoids: an update, Nat. Prod. Rep., 37, 999, 10.1039/C9NP00062C Manzetti, 2014, Thiamin function, metabolism, uptake, and transport, Biochemistry, 53, 821, 10.1021/bi401618y Moloney, 2018, ROS signalling in the biology of cancer, Semin. Cell Dev. Biol., 80, 50, 10.1016/j.semcdb.2017.05.023 Perillo, 2020, ROS in cancer therapy: the bright side of the moon, Exp. Mol. Med., 52, 192, 10.1038/s12276-020-0384-2 Prouillet, 2004, Stimulatory effect of naturally occurring flavonols quercetin and kaempferol on alkaline phosphatase activity in MG-63 human osteoblasts through ERK and estrogen receptor pathway, Biochem. Pharmacol., 67, 1307, 10.1016/j.bcp.2003.11.009 Pyee, 2014, Suppression of inflammatory responses by Handelin, a guaianolide dimer from Chrysanthemum boreale, via downregulation of NF-κB signaling and pro-inflammatory cytokine production, J. Nat. Prod., 77, 917, 10.1021/np4009877 Rallis, 2021, Chemoradiotherapy in cancer treatment: rationale and clinical applications, Anticancer Res., 41, 1, 10.21873/anticanres.14746 Reiter, 2020, Melatonin inhibits Warburg-dependent cancer by redirecting glucose oxidation to the mitochondria: a mechanistic hypothesis, Cell. Mol. Life Sci., 77, 2527, 10.1007/s00018-019-03438-1 Salamon, 2017, Glucose metabolism in cancer and ischemia: possible therapeutic consequences of the Warburg Effect, Nutr. Cancer, 69, 177, 10.1080/01635581.2017.1263751 Sharma, 2014, Alkaline phosphatase: an overview, Indian J. Clin. Biochem., 29, 269, 10.1007/s12291-013-0408-y Sosa, 2013, Oxidative stress and cancer: an overview, Ageing Res. Rev., 12, 376, 10.1016/j.arr.2012.10.004 Stacpoole, 2017, Therapeutic targeting of the pyruvate dehydrogenase complex/pyruvate dehydrogenase kinase (PDC/PDK) axis in cancer, J. Natl. Cancer Inst., 109, djx071, 10.1093/jnci/djx071 Su, 2021, New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity, Acta Pharm. Sin. B., 11, 1648, 10.1016/j.apsb.2020.12.006 Sun, 2015, Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis, J. Recept. Signal Transduct. Res., 35, 600, 10.3109/10799893.2015.1030412 Sung, 2021, Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 0, 1 Vander Heiden, 2009, Understanding the Warburg effect: the metabolic requirements of cell proliferation, Science, 324, 1029, 10.1126/science.1160809 Wang, 2016, Bufalin suppresses hepatocellular carcinoma invasion and metastasis by targeting HIF-1α via the PI3K/AKT/mTOR pathway, Oncotarget, 7, 20193, 10.18632/oncotarget.7935 Wick, 2018, Metastases of malignant neoplasms: Historical, biological, and clinical considerations, Semin. Diagn. Pathol., 35, 112, 10.1053/j.semdp.2017.11.009 Woolbright, 2019, Metabolic flexibility in cancer: targeting the pyruvate dehydrogenase kinase: pyruvate dehydrogenase axis, Mol. Cancer Ther., 18, 1673, 10.1158/1535-7163.MCT-19-0079 Xue, 2019, Artemisianins A-D, new stereoisomers of seco-guaianolide involved heterodimeric [4+2] adducts from Artemisia argyi induce apoptosis via enhancement of endoplasmic reticulum stress, Bioorg. Chem., 84, 295, 10.1016/j.bioorg.2018.11.013 Yu, 2019, Systematic re-analysis strategy of serum indices identifies alkaline phosphatase as a potential predictive factor for cervical cancer, Oncol. Lett., 18, 2356 Yuan, 2015, Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways, Amino Acids, 47, 2475, 10.1007/s00726-015-2020-3 Zhu, 2016, Molecular mechanisms of cisplatin resistance in cervical cancer, Drug Des Devel Ther., 10, 1885, 10.2147/DDDT.S106412