Mechanisms of Mechanotransduction

Developmental Cell - Tập 10 - Trang 11-20 - 2006
A. Wayne Orr1, Brian P. Helmke1,2, Brett R. Blackman1,2, Martin A. Schwartz1,2,3
1Cardiovascular Research Center, University of Virginia, 415 Lane Road, Charlottesville, Virginia 22908
2Department of Biomedical Engineering, University of Virginia, 415 Lane Road, Charlottesville, Virginia 22908
3Department of Microbiology, University of Virginia, 415 Lane Road, Charlottesville, Virginia 22908

Tài liệu tham khảo

Alberts, 2002 Alenghat, 2004, Global cytoskeletal control of mechanotransduction in kidney epithelial cells, Exp. Cell Res., 301, 23, 10.1016/j.yexcr.2004.08.003 Anderson, 2005, Nano-microscale models of periosteocytic flow show differences in stresses imparted to cell body and processes, Ann. Biomed. Eng., 33, 52, 10.1007/s10439-005-8962-y Balaban, 2001, Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates, Nat. Cell Biol., 3, 466, 10.1038/35074532 Beevers, 2001, ABC of hypertension: the pathophysiology of hypertension, BMJ, 322, 912, 10.1136/bmj.322.7291.912 Beloussov, 1980, The role of tensile fields and contact cell polarization in the morphogenesis of amphibian axial rudiments, Rouxs Arch. Dev. Biol., 188, 1, 10.1007/BF00848603 Beloussov, 1988, The role of external tensions in differentiation of Xenopus laevis embryonic tissues, Cell Differ. Dev., 25, 165, 10.1016/0922-3371(88)90113-X Bernatchez, 2005, Dissecting the molecular control of endothelial NO synthase by caveolin-1 using cell-permeable peptides, Proc. Natl. Acad. Sci. USA, 102, 761, 10.1073/pnas.0407224102 Brancaccio, 2003, Melusin, a muscle-specific integrin β1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload, Nat. Med., 9, 68, 10.1038/nm805 Burger, 1999, Mechanotransduction in bone—role of the lacuno-canalicular network, FASEB J., 13, S101, 10.1096/fasebj.13.9001.s101 Burridge, 1996, Focal adhesions, contractility, and signaling, Annu. Rev. Cell Dev. Biol., 12, 463, 10.1146/annurev.cellbio.12.1.463 Butler, 2001, Shear stress induces a time- and position-dependent increase in endothelial cell membrane fluidity, Am. J. Physiol. Cell Physiol., 280, C962, 10.1152/ajpcell.2001.280.4.C962 Cartwright, 2004, Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates, Proc. Natl. Acad. Sci. USA, 101, 7234, 10.1073/pnas.0402001101 Corey, 2004, TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells, Nature, 432, 723, 10.1038/nature03066 Correa-Meyer, 2002, Cyclic stretch activates ERK1/2 via G proteins and EGFR in alveolar epithelial cells, Am. J. Physiol. Lung Cell. Mol. Physiol., 282, L883, 10.1152/ajplung.00203.2001 Dai, 2004, Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature, Proc. Natl. Acad. Sci. USA, 101, 14871, 10.1073/pnas.0406073101 Davies, 1995, Flow-mediated endothelial mechanotransduction, Physiol. Rev., 75, 519, 10.1152/physrev.1995.75.3.519 Davis, 2001, Integrins and mechanotransduction of the vascular myogenic response, Am. J. Physiol. Heart Circ. Physiol., 280, H1427, 10.1152/ajpheart.2001.280.4.H1427 Delmas, 2004, Polycystins: from mechanosensation to gene regulation, Cell, 118, 145, 10.1016/j.cell.2004.07.007 Drummond, 2004, Degenerin/epithelial Na+ channel proteins: components of a vascular mechanosensor, Hypertension, 44, 643, 10.1161/01.HYP.0000144465.56360.ad Du, 2004, Mechanosensory function of microvilli in the kidney proximal tubule, Proc. Natl. Acad. Sci. USA, 101, 13068, 10.1073/pnas.0405179101 Earley, 2004, Critical role for transient receptor potential channel TRPM4 in myogenic constriction of cerebral arteries, Circ. Res., 95, 922, 10.1161/01.RES.0000147311.54833.03 Eberl, 2000, Genetically similar transduction mechanisms for touch and hearing in Drosophila, J. Neurosci., 20, 5981, 10.1523/JNEUROSCI.20-16-05981.2000 Evans, 1976, Elastic area compressibility modulus of red cell membrane, Biophys. J., 16, 585, 10.1016/S0006-3495(76)85713-X Farge, 2003, Mechanical induction of Twist in the Drosophila foregut/stomodeal primordium, Curr. Biol., 13, 1365, 10.1016/S0960-9822(03)00576-1 Florian, 2003, Heparan sulfate proteoglycan is a mechanosensor on endothelial cells, Circ. Res., 93, e136, 10.1161/01.RES.0000101744.47866.D5 Frangos, 1999, Localization of atherosclerosis: role of hemodynamics, Arch. Surg., 134, 1142, 10.1001/archsurg.134.10.1142 Fritton, 2000, Quantifying the strain history of bone: spatial uniformity and self-similarity of low-magnitude strains, J. Biomech., 33, 317, 10.1016/S0021-9290(99)00210-9 Garcia-Cardena, 2001, Biomechanical activation of vascular endothelium as a determinant of its functional phenotype, Proc. Natl. Acad. Sci. USA, 98, 4478, 10.1073/pnas.071052598 Gimbrone, 2000, Endothelial dysfunction, hemodynamic forces, and atherogenesis, Ann. N Y Acad. Sci., 902, 230, 10.1111/j.1749-6632.2000.tb06318.x Grierson, 1995, Shear stress-induced [Ca2+]i transients and oscillations in mouse fibroblasts are mediated by endogenously released ATP, J. Biol. Chem., 270, 4451, 10.1074/jbc.270.9.4451 Guo, 2000, A hydrodynamic mechanosensory hypothesis for brush border microvilli, Am. J. Physiol. Cell Physiol., 279, F698, 10.1152/ajprenal.2000.279.4.F698 Gutierrez, 2003, Continuous mechanical contraction modulates expression of alveolar epithelial cell phenotype, Am. J. Respir. Cell Mol. Biol., 29, 81, 10.1165/rcmb.2002-0135OC Haidekker, 2000, Fluid shear stress increases membrane fluidity in endothelial cells: a study with DCVJ fluorescence, Am. J. Physiol. Heart Circ. Physiol., 278, H1401, 10.1152/ajpheart.2000.278.4.H1401 Hallworth, 1995, Passive compliance and active force generation in the guinea pig outer hair cell, J. Neurophysiol., 74, 2319, 10.1152/jn.1995.74.6.2319 Hamill, 2001, Molecular basis of mechanotransduction in living cells, Physiol. Rev., 81, 685, 10.1152/physrev.2001.81.2.685 Han, 2004, Conversion of mechanical force into biochemical signaling, J. Biol. Chem., 279, 54793, 10.1074/jbc.M406880200 Han, 2004, Mechanotransduction and strain amplification in osteocyte cell processes, Proc. Natl. Acad. Sci. USA, 101, 16689, 10.1073/pnas.0407429101 Helmke, 2003, Mapping mechanical strain of an endogenous cytoskeletal network in living endothelial cells, Biophys. J., 84, 2691, 10.1016/S0006-3495(03)75074-7 Houston, 1999, Fluid shear stress induction of the tissue factor promoter in vitro and in vivo is mediated by Egr-1, Arterioscler. Thromb. Vasc. Biol., 19, 281, 10.1161/01.ATV.19.2.281 Hove, 2003, Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis, Nature, 421, 172, 10.1038/nature01282 Huang, 1999, The structural and mechanical complexity of cell-growth control, Nat. Cell Biol., 1, E131, 10.1038/13043 Jalali, 2001, Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands, Proc. Natl. Acad. Sci. USA, 98, 1042, 10.1073/pnas.98.3.1042 Ji, 2003, Shear stress causes nuclear localization of endothelial glucocorticoid receptor and expression from the GRE promoter, Circ. Res., 92, 279, 10.1161/01.RES.0000057753.57106.0B Jin, 2003, Ligand independent activation of VEGF receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthesis, Circ. Res., 93, 354, 10.1161/01.RES.0000089257.94002.96 Jones, 2004, Measuring hemodynamic changes during mammalian development, Am. J. Physiol. Heart Circ. Physiol., 287, H1561, 10.1152/ajpheart.00081.2004 Katsumi, 2004, Integrins in mechanotransduction, J. Biol. Chem., 279, 12001, 10.1074/jbc.R300038200 Katsumi, 2005, Integrin activation and matrix binding mediate cellular responses to mechanical stretch, J. Biol. Chem., 280, 16546, 10.1074/jbc.C400455200 Knoll, 2002, The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy, Cell, 111, 943, 10.1016/S0092-8674(02)01226-6 Lammerding, 2004, Mechanotransduction in cardiac myocytes, Ann. N Y Acad. Sci., 1015, 53, 10.1196/annals.1302.005 Lammerding, 2004, Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction, J. Clin. Invest., 113, 370, 10.1172/JCI200419670 Lee, 2005, Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress, Mol. Biol. Cell, 16, 871, 10.1091/mbc.e03-12-0910 Liu, 2000, Invited review: mechanochemical signal transduction in the fetal lung, J. Appl. Physiol., 89, 2078, 10.1152/jappl.2000.89.5.2078 Maroto, 2005, TRPC1 forms the stretch-activated cation channel in vertebrate cells, Nat. Cell Biol., 7, 179, 10.1038/ncb1218 Martinac, 2004, Mechanosensitive ion channels: molecules of mechanotransduction, J. Cell Sci., 117, 2449, 10.1242/jcs.01232 Martinac, 2002, Gramicidin A channels switch between stretch activation and stretch inactivation depending on bilayer thickness, Proc. Natl. Acad. Sci. USA, 99, 4308, 10.1073/pnas.072632899 Mazzolai, 2002, Tissue factor activity is upregulated in human endothelial cells exposed to oscillatory shear stress, Thromb. Haemost., 87, 1062, 10.1055/s-0037-1613133 McGrath, 2003, Two populations of node monocilia initiate left-right asymmetry in the mouse, Cell, 114, 61, 10.1016/S0092-8674(03)00511-7 Miralles, 2003, Actin dynamics control SRF activity by regulation of its coactivator MAL, Cell, 113, 329, 10.1016/S0092-8674(03)00278-2 Mochizuki, 2003, Role of hyaluronic acid glycosaminoglycans in shear-induced endothelium-derived nitric oxide release, Am. J. Physiol. Heart Circ. Physiol., 285, H722, 10.1152/ajpheart.00691.2002 Mohan, 1997, Differential activation of NF-κB in human aortic endothelial cells conditioned to specific flow environments, Am. J. Physiol. Cell Physiol., 273, C572, 10.1152/ajpcell.1997.273.2.C572 Munevar, 2001, Traction force microscopy of migrating normal and H-ras transformed 3T3 fibroblasts, Biophys. J., 80, 1744, 10.1016/S0006-3495(01)76145-0 Murray, 1990, The effect of strain on bone cell prostaglandin E2 release: a new experimental method, Calcif. Tissue Int., 47, 35, 10.1007/BF02555863 Nauli, 2003, Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells, Nat. Genet., 33, 129, 10.1038/ng1076 Neidlinger-Wilke, 1995, Human osteoblasts from younger normal and osteoporotic donors show differences in proliferation and TGF β-release in response to cyclic strain, J. Biomech., 28, 1411, 10.1016/0021-9290(95)00089-5 Nonaka, 1998, Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein, Cell, 95, 829, 10.1016/S0092-8674(00)81705-5 Nonaka, 2002, Determination of left-right patterning of the mouse embryo by artificial nodal flow, Nature, 418, 96, 10.1038/nature00849 Oberhauser, 1998, The molecular elasticity of the extracellular matrix protein tenascin, Nature, 393, 181, 10.1038/30270 O'Hagan, 2005, The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals, Nat. Neurosci., 8, 43, 10.1038/nn1362 Okada, 2005, Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination, Cell, 121, 633, 10.1016/j.cell.2005.04.008 Osawa, 2002, Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?, J. Cell Biol., 158, 773, 10.1083/jcb.200205049 Park, 2000, Caveolin-1 regulates shear stress-dependent activation of extracellular signal-regulated kinase, Am. J. Physiol. Heart Circ. Physiol., 278, H1285, 10.1152/ajpheart.2000.278.4.H1285 Paszek, 2005, Tensional homeostasis and the malignant phenotype, Cancer Cell, 8, 241, 10.1016/j.ccr.2005.08.010 Ponik, 2004, Formation of focal adhesions on fibronectin promotes fluid shear stress induction of COX-2 and PGE2 release in MC3T3-E1 osteoblasts, J. Appl. Physiol., 97, 135, 10.1152/japplphysiol.01260.2003 Raisz, 1999, Physiology and pathophysiology of bone remodeling, Clin. Chem., 45, 1353 Rizzo, 1998, In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association, J. Biol. Chem., 273, 34724, 10.1074/jbc.273.52.34724 Roovers, 2003, Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases, Mol. Biol. Cell, 23, 4283, 10.1128/MCB.23.12.4283-4294.2003 Sadoshima, 1993, Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro, Cell, 75, 977, 10.1016/0092-8674(93)90541-W Sanchez-Esteban, 2004, Mechanical stretch induces fetal type II cell differentiation via an epidermal growth factor receptor-extracellular-regulated protein kinase signaling pathway, Am. J. Respir. Cell Mol. Biol., 30, 76, 10.1165/rcmb.2003-0121OC Sawada, 2002, Force transduction by triton cytoskeletons, J. Cell Biol., 156, 609, 10.1083/jcb.200110068 Serluca, 2002, Endothelial signaling in kidney morphogenesis: a role for hemodynamic forces, Curr. Biol., 12, 492, 10.1016/S0960-9822(02)00694-2 Shay-Salit, 2002, VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells, Proc. Natl. Acad. Sci. USA, 99, 9462, 10.1073/pnas.142224299 Shyy, 1994, Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium, Proc. Natl. Acad. Sci. USA, 91, 4678, 10.1073/pnas.91.11.4678 Sidi, 2003, NompC TRP channel required for vertebrate sensory hair cell mechanotransduction, Science, 301, 96, 10.1126/science.1084370 Siemens, 2004, Cadherin 23 is a component of the tip link in hair-cell stereocilia, Nature, 428, 950, 10.1038/nature02483 Smith, 2003, Near-wall micro-PIV reveals a hydrodynamically relevant endothelial surface layer in venules in vivo, Biophys. J., 85, 637, 10.1016/S0006-3495(03)74507-X Sollner, 2004, Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells, Nature, 428, 955, 10.1038/nature02484 Somogyi, 2004, Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration, Dev. Cell, 7, 85, 10.1016/j.devcel.2004.05.020 Spector, 1999, Nonlinear active force generation by cochlear outer hair cell, J. Acoust. Soc. Am., 105, 2414, 10.1121/1.426846 Sukharev, 1999, Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL, J. Gen. Physiol., 113, 525, 10.1085/jgp.113.4.525 Supp, 1999, Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries, Development, 126, 5495, 10.1242/dev.126.23.5495 Takahashi, 1997, Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress, J. Vasc. Res., 34, 212, 10.1159/000159225 Tanaka, 2005, FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination, Nature, 435, 172, 10.1038/nature03494 Tschumperlin, 2004, Mechanotransduction through growth-factor shedding into the extracellular space, Nature, 429, 83, 10.1038/nature02543 Tzima, 2001, Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment, EMBO J., 20, 4639, 10.1093/emboj/20.17.4639 Tzima, 2002, Activation of Rac in endothelial cells in response to fluid shear stress mediates gene expression and cell alignment, EMBO J., 21, 6791, 10.1093/emboj/cdf688 Tzima, 2003, Localized Cdc42 activation detected using a novel assay mediates MTOC positioning in endothelial cells in response to fluid shear stress, J. Biol. Chem., 278, 31020, 10.1074/jbc.M301179200 Tzima, 2005, A mechanosensory complex that mediates the endothelial cell response to fluid shear stress, Nature, 437, 426, 10.1038/nature03952 Vink, 2000, Capillary endothelial surface layer selectively reduces plasma solute distribution volume, Am. J. Physiol. Heart Circ. Physiol., 278, H285, 10.1152/ajpheart.2000.278.1.H285 Wang, 2000, Substrate flexibility regulates growth and apoptosis of normal but not transformed cells, Am. J. Physiol. Cell Physiol., 279, C1345, 10.1152/ajpcell.2000.279.5.C1345 Weinbaum, 1994, A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses, J. Biomech., 27, 339, 10.1016/0021-9290(94)90010-8 Weinbaum, 2003, Mechanotransduction and the flow across the endothelial glycocalyx, Proc. Natl. Acad. Sci. USA, 100, 7988, 10.1073/pnas.1332808100 Welsh, 2002, Transient receptor potential channels regulate myogenic tone of resistance arteries, Circ. Res., 90, 248, 10.1161/hh0302.105662 Weyts, 2002, ERK activation and α v β 3 integrin signaling through Shc recruitment in response to mechanical stimulation in human osteoblasts, J. Cell Biochem., 87, 85, 10.1002/jcb.10278 Wirtz, 2000, The effects of mechanical forces on lung functions, Respir. Physiol., 119, 1, 10.1016/S0034-5687(99)00092-4 You, 2001, A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix, J. Biomech., 34, 1375, 10.1016/S0021-9290(01)00107-5 Zhong, 1998, Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly, J. Cell Biol., 141, 539, 10.1083/jcb.141.2.539 Zou, 2004, Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II, Nat. Cell Biol., 6, 499, 10.1038/ncb1137