The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

Ahringer, 1991, Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3′ untranslated region, Nature, 349, 346, 10.1038/349346a0 Ahringer, 1992, The Caenorhabditis elegans sex determining gene fem-3 is regulated post-transcriptionally, EMBO J., 11, 2303, 10.1002/j.1460-2075.1992.tb05289.x Ambros, 1989, A hierarchy of regulatory genes controls a larva-to-adult developmental switch in C. elegans, Cell, 57, 49, 10.1016/0092-8674(89)90171-2 Ambros, 1984, Heterochronic mutants of the nematode Caenorhabditis elegans, Science, 266, 409, 10.1126/science.6494891 Ambros, 1987, The lin-14 locus of Caenorhabditis elegans controls the time of expression of specific postembryonic developmental events, Genes Dev., 1, 398, 10.1101/gad.1.4.398 Arasu, 1991, Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28, Genes Dev., 5, 1825, 10.1101/gad.5.10.1825 Ausubel, 1989 Blum, 1990, A model for RNA editing in kinetoplastid mitochondria: “guide” RNA molecules transcribed from maxicircle DNA provide the edited information, Cell, 60, 189, 10.1016/0092-8674(90)90735-W Brannan, 1990, The product of the H19 gene may function as an RNA, Mol. Cell. Biol., 10, 28, 10.1128/MCB.10.1.28 Brenner, 1973, The genetics of Caenorhabditis elegans, Genetics, 77, 79 Brockdorff, 1992, The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus, Cell, 71, 515, 10.1016/0092-8674(92)90519-I Carle, 1985, An electrophoretic karyotype for yeast, 82, 3756 Chalfie, 1981, Mutations that lead to reiterations in the cell lineages of C. elegans, Cell, 24, 59, 10.1016/0092-8674(81)90501-8 Coulson, 1986, Toward a physical map of the genome of the nematode Caenorhabditis elegans, 83, 7821 Coulson, 1988, Genome linking with yeast artificial chromosomes, Nature, 335, 184, 10.1038/335184a0 Datta, 1991, Genetic evidence for base pairing between U2 and U6 snRNA in mammalian mRNA splicing, Nature, 352, 821, 10.1038/352821a0 Devereux, 1984, A comprehensive set of sequence analysis programs for the VAX, Nucl. Acids Res., 12, 387, 10.1093/nar/12.1Part1.387 Eguchi, 1991, Antisense RNA, Annu. Rev. Biochem., 60, 631, 10.1146/annurev.bi.60.070191.003215 Feinberg, 1983, A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity, Anal. Biochem., 132, 6, 10.1016/0003-2697(83)90418-9 Gallie, 1991, The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency, Genes Dev., 5, 2108, 10.1101/gad.5.11.2108 Gavis, 1992, Localization of nanos RNA controls embryonic polarity, Cell, 71, 301, 10.1016/0092-8674(92)90358-J Goodwin, 1993, Translational regulation of tra-2 by its 3′ untranslated region controls sexual identity in C. elegans, Cell, 75, 329, 10.1016/0092-8674(93)80074-O Green, 1991, Biochemical mechanisms of constitutive and regulated pre-mRNA splicing, Annu. Rev. Cell Biol., 7, 559, 10.1146/annurev.cb.07.110191.003015 Guthrie, 1991, Messenger RNA splicing in yeast: clues to why the spliceosome is a ribonucleoprotein, Science, 253, 157, 10.1126/science.1853200 Hildebrandt, 1992, Differential antisense transcription from the Dictyostelium EB4 gene locus: implications on antisense-mediated regulation of mRNA stability, Cell, 69, 197, 10.1016/0092-8674(92)90130-5 Jackson, 1990, Do the poly(A) tail and 3′ untranslated region control mRNA translation?, Cell, 62, 15, 10.1016/0092-8674(90)90235-7 Jaeger, 1989, Improved predictions of secondary structures for RNA, 86, 7706 Jaeger, 1989, Predicting optimal and suboptimal secondary structure for RNA, Meth. Enzymol., 183, 281, 10.1016/0076-6879(90)83019-6 Kimelman, 1989, An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes, Cell, 59, 687, 10.1016/0092-8674(89)90015-9 Kittle, 1989, Insertion sequence IS10 anti-sense pairing initiates by an interaction between the 5′ end of the target RNA and a loop in the anti-sense RNA, J. Mol. Biol., 210, 561, 10.1016/0022-2836(89)90132-0 Kunkel, 1987, Rapid and efficient site-specific mutagenesis without phenotypic selection, Meth. Enzymol., 154, 367, 10.1016/0076-6879(87)54085-X Kwon, 1991, Cytoplasmic protein binding to highly conserved sequences in the 3′ untranslated region of mouse protamine 2 mRNA, a translationally regulated transcript of male germ cells, 88, 3584 Leverette, 1992, Mouse U14 snRNA is a processed intron of the cognate hsc70 heat shock pre-messenger RNA, Cell, 71, 1215, 10.1016/S0092-8674(05)80069-8 Liao, 1987, Control of gene expression in bacteriophage P22 by a small antisense RNA, Genes Dev., 1, 197, 10.1101/gad.1.2.197 Madhani, 1992, A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome, Cell, 71, 803, 10.1016/0092-8674(92)90556-R Marck, 1988, ‘DNA Strider’: a C program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers, Nucl. Acids Res., 16, 1829, 10.1093/nar/16.5.1829 Mello, 1991, Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences, EMBO J., 10, 3959, 10.1002/j.1460-2075.1991.tb04966.x Ruvkun, 1989, The Caenorhabditis elegans heterochronic gene lin-14 encodes a nuclear protein that forms a temporal developmental switch, Nature, 338, 313, 10.1038/338313a0 Ruvkun, 1989, Molecular genetics of the Caenorhabditis elegans heterochronic gene lin-14, Genetics, 121, 501, 10.1093/genetics/121.3.501 Sachs, 1989, The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation, Cell, 58, 857, 10.1016/0092-8674(89)90938-0 Sachs, 1992, Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast, Cell, 70, 961, 10.1016/0092-8674(92)90246-9 Sanger, 1977, DNA sequencing by chain terminating inhibitors, 74, 5463 Simons, 1988, Naturally occurring antisense RNA control: a brief review, Gene, 72, 35, 10.1016/0378-1119(88)90125-4 Simpson, 1990, RNA editing: a novel genetic phenomenon?, Science, 250, 512, 10.1126/science.1700474 Sulston, 1992, The C. elegans genome sequence project: a beginning, Nature, 356, 37, 10.1038/356037a0 Tycowski, 1993, A small nucleolar RNA is processed from an intron of the human gene encoding ribosomal protein S3, Genes Dev., 7, 1176, 10.1101/gad.7.7a.1176 Wassarman, 1992, Interactions of small nuclear RNAs with precursor messenger RNA during in vitro splicing, Science, 257, 1918, 10.1126/science.1411506 Wharton, 1991, RNA regulatory elements mediate control of Drosophila body pattern by the posterior morphogen nanos, Cell, 67, 955, 10.1016/0092-8674(91)90368-9 Wightman, 1991, Negative regulatory sequences in the lin-14 3′-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development, Genes Dev., 5, 1813, 10.1101/gad.5.10.1813 Wightman, 1993, Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans, Cell, 75, 10.1016/0092-8674(93)90530-4 1988 Zuker, 1989, On finding all suboptimal foldings of an RNA molecule, Science, 244, 48, 10.1126/science.2468181