Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis

The Lancet - Tập 340 - Trang 152-156 - 1992
M.T. Nurmohamed1, H.R. Buller1, E. Dekker1, D.W. Hommes1, F.R. Rosendaal2, E. Briet2, J.P. Vandenbroucke3
1Centre for Haemostasis, Thrombosis, Atherosclerosis and Inflammation Research, Academic Medical Centre, Amsterdam, the Netherlands
2Department of Haematology, University Hospital Leiden, Netherlands
3Department of Clinical Epidemiology, University Hospital Leiden, Leiden, Netherlands

Tài liệu tham khảo

Carter, 1987, The epidemiology of venous thrombosis, 1185 National Institute of Health Consensus Development Conference, 1986, JAMA, 256, 744, 10.1001/jama.256.6.744 Colditz, 1986, Lancet, ii, 143, 10.1016/S0140-6736(86)91955-0 Clagett, 1988, Prevention of venous thromboembolism in general surgical patients, Ann Surg, 208, 227, 10.1097/00000658-198808000-00016 Collins, 1988, Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin, N Engl J Med, 318, 1162, 10.1056/NEJM198805053181805 Andersson, 1976, Anticoagulant properties of heparin fractionated by affinity chromatography on matrixbound antithrombin III and by gel filtration, Thromb Res, 9, 575, 10.1016/0049-3848(76)90105-5 ten Cate, 1984, Automated amidolytic method for determining heparin, a heparinoid, and a low-Mr heparin fragment, based on their anti-Xa activity, Clin Chem, 30, 860, 10.1093/clinchem/30.6.860 Salzman, 1980, Effect of heparin and heparin fractions on platelet aggregation, J Clin Invest, 65, 64, 10.1172/JCI109661 Büller, 1991, Deep venous thrombosis: new non-invasive diagnostic tests, Thromb Haemostas, 66, 133, 10.1055/s-0038-1646381 1985, 285 Miettinen, 1976, Estimability and estimation in case-referent studies, Am J Epidemiol, 103, 226, 10.1093/oxfordjournals.aje.a112220 Bergqvist, 1986, Low molecular weight heparin once daily compared with conventional low-dose heparin twice daily. A prospective double-blind multicentre trial on prevention of postoperative thrombosis, Br J Surg, 73, 204, 10.1002/bjs.1800730316 Bergqvist, 1988, Low molecular weight heparin given in the evening before surgery compared with conventional low-dose heparin in prevention of thrombosis, Br J Surg, 75, 888, 10.1002/bjs.1800750920 Borstad, 1988, Comparison of low molecular weight heparin vs unfractionated heparin in gynaecological surgery, Acta Obstet Gynecol Scand, 67, 99, 10.3109/00016348809004178 Briel, 1988, ThromboembolieProphylaxe bie Hysterektomien mit dem niedermolekularem Heparin Fragmin, Gerburts Frauenheilk, 48, 160, 10.1055/s-2008-1035716 Kominger, 1987, Randomized trial of low molecular weight heparin (LMWH) versus low dose heparin-acenocoumarin (H/AC) in patients with hip fracture— thromboprophylactic effect and bleeding complications, Thromb Haemostas, 62, 187 Onarheim, 1986, A low molecular weight heparin (Kabi 2165) for prophylaxis of postoperative deep venous thrombosis, Acta Chir Scand, 152, 593 Schmitz-Huebner, 1984, Clinical efficacy of low molecular weight heparin in postoperative thrombosis prophylaxis, Klin Wschr, 62, 349, 10.1007/BF01716253 Welzel, 1988, Antithrombotic defense during the postoperative period, Arzneimittel Forsch, 38, 120 Breyer, 1987, Prevention of deep vein thrombosis in orthopedic surgery: Fragmin versus heparin-DHE, Thromb Haemostas, VII, 23 Catania, 1988, Prevention of postoperative deep vein thrombosis by two diffrent heparin types, Int J Clin Pharmacol Ther Toxicol, 26, 304 Haas, 1987, Prophylaxis of deep vein thrombosis in high risk patients undergoing total hip replacement with low molecular weight heparin plus dihydroergotamine, Arzneimittel Forsch, 37, 839 Heilmann, 1989, Thrombosephrophylaxe in der Gynakologie: Doppelblindvergleich zwischen neiedermolekularem (LMWH) und unfraktioniertem (UFH) Heparin, Geburts Frauenheilk, 49, 803, 10.1055/s-2008-1036089 Hoffmann, 1987, Perioperative ThromboembolieProphylaxe: niedrig dosiertes Heparin oder low molecular Heparin-DHE, Vor- und Nachteile, Helv Chir Acta, 54, 521 Lassen, 1988, Heparin-dihydroergotamine for venous thrombosis prophylaxis: comparison of low-dose heparin and low molecular weight heparin in hip surgery, Br J Surg, 75, 686, 10.1002/bjs.1800750720 Lassen, 1989, Prevention of thromboembolism in hip fracture patients, Arch Orthop Trauma Surg, 108, 10, 10.1007/BF00934150 Monreal, 1989, A prospective double-blind trial of low molecular weight heparin once daily compared with conventional low-dose heparin three times daily to prevent pulmonary embolism and venous thrombosis in patients with hip fracture, J Trauma, 29, 873, 10.1097/00005373-198906000-00028 Pini, 1989, Int Angio, 8, 134 Salcuni, 1988, A new low molecular weight heparin for deep vein thrombosis prevention: effectiveness in postoperative patients, Curr Ther Res, 43, 824 Steiner, 1989, A prospective randomized trial of low molecular weight heparin-DHE and conventional heparin-DHE (with acenocoumarol) in patients undergoing gynaecological surgery, Arch Gynecol Obstet, 244, 141, 10.1007/BF00931291 Von Voigt, 1986, Wirksamheit und unerwünschte Wirkungen von niedermole-Kularem Heparin-dihydroergotamin zur Thromboembolieprophylaxe in der Abdominalchirurgie, ZentBl Chir, 111, 1296 Adolf, 1989, Thromboembolieprophylaxe mit niedermolekularem Heparin in der Abdominalchirurgie, Dt Med Wschr, 114, 48, 10.1055/s-2008-1066550 Barre, 1987, Efficacité et tolérance comparées du Kabi 2165 et de l'héparine standard dans la prévention des thromboses veineuses profondes au cours de prothèses totale de hanche, J Mal Vasc, 12, 90 Baumgartner, 1989, Prevention of postoperative deep vein thrombosis by one daily injection of low molecular weight heparin and dihydroergotamine, Vasa, 18, 152 Blum, 1989, DVT prophylaxis for digestive tract cancer comparing the LMW heparinoid ORG 10172 (Lomoparan) with calcium heparin, Thromb Haemostas, 62, 126 Cade, 1989, Org 10172 or heparin for preventing venous thrombosis (VT) after surgery for malignant disease? A double blind multi-centre comparison, Thromb Haemostas, 62, 42 Caen, 1988, A randomized double-blind study between a low molecular weight heparin Kabi 2165 and standard heparin in the prevention of deep vein thrombosis in general surgery, Thromb Haemostas, 59, 216, 10.1055/s-0038-1642757 Dahan, 1989, Prevention of post-operative deep vein thrombosis (DVT) in malignant patients by Fraxiparine (a low molecular weight heparin). A cooperative trial, Thromb Haemostas, 62, 519 Dechavanne, 1989, Randomized trial of a low molecular weight heparin (Kabi 2165) versus adjusted dose subcutaneous standard heparin in the prophylaxis of deep vein thrombosis after elective hip surgery, Haemostasis, 1, 5 Encke, 1988, Comparison of a low molecular weight and unfractionated heparin for the prevention of deep vein thrombosis in patients undergoing abdominal surgery, Br J Surg, 75, 1058, 10.1002/bjs.1800751105 Eriksson, 1989, Comparison of low molecular weight heparin and unfractionated heparin in prophylaxis of deep vein thrombosis and pulmonary embolism in total hip replacement, Thromb Haemostas, 62, 470 Estoppey, 1989, Org 10172 (Lomoparan) versus heparin-DHE in prevention of thromboembolism in total hip replacement—a multicentre trial, Thromb Haemostas, 62, 356 Fricker, 1988, Low dose heparin versus low molecular weight heparin (Kabi 2165, Fragmin) in the prophylaxis of thromboembolic complications of abdominal oncological surgery, Eur J Clin Invest, 18, 561, 10.1111/j.1365-2362.1988.tb01268.x Hartl, 1990, Prophylaxis of thromboembolism in general surgery: comparison between standard heparin and Fragmin, Thromb Res, 57, 577, 10.1016/0049-3848(90)90074-M Kakkar, 1985, Efficacy and safety of low molecular weight heparin (CY216) in preventing postoperative thrombo-embolism: a cooperative study, Br J Surg, 72, 786, 10.1002/bjs.1800721006 Koller, 1986, Low molecular weight heparin (Kabi 2165) as thromboprophylaxis in elective visceral surgery, Thromb Haemostas, 56, 243, 10.1055/s-0038-1661658 Leizorovicz, 1989, Comparison of two doses of low molecular weight heparin in the prevention of post-operative vein thrombosis (DVT), Thromb Haemostas, 62, 521 Leyvraz, 1990, Prevention of deep vein thrombosis after total hip replacement: randomized comparison between adjusted dose unfractionated heparin and low molecular weight heparin (CY216), 105 Planes, 1988, Thromb Haemostas, 60, 407, 10.1055/s-0038-1646980 Samama, 1988, Low molecular weight heparin with unfractionated heparin in prevention of postoperative thrombosis, Br J Surg, 75, 128, 10.1002/bjs.1800750213 Sasahara, 1986, Low molecular weight heparin plus dihydroergotamine for prophylaxis of postoperative deep vein thrombosis, Br J Surg, 73, 697, 10.1002/bjs.1800730906 Verardi, 1988, A multicentre study on LMW-heparin effectiveness in preventing postsurgical thrombosis, Int Angio, 7, 19 Verardi, 1989, Curr Ther Res, 46, 366 Welzel, 1989, Fixed combinations of low molecular weight or unfractionated heparin plus dihydroergotamine in the prevention of postoperative deep vein thrombosis, Thromb Haemostas, 62, 523 Cruickshank, 1989, An elevation of impedance plethysmography and 125-I-fibrinogen legscanning in patients following hip surgery, Thromb Haemostas, 62, 830, 10.1055/s-0038-1651012 Laupacis, 1988, An assessment of clinically useful measures of the consequences of treatment, N Engl J Med, 318, 1728, 10.1056/NEJM198806303182605 Light, 1984