Opiates as potential cofactors in progression of HIV-1 infections to AIDS

Alcabes, 1993, Incubation period of human immunodeficiency virus, Epidemiol. Rev., 15, 303, 10.1093/oxfordjournals.epirev.a036122 Alcabes, 1993, CD4+ lymphocyte level and rate of decline as predictors of AIDS in intravenous drug users with HIV infection, AIDS, 7, 513, 10.1097/00002030-199304000-00010 Alkhatib, 1996, CC CKR5: A RANTES, MIP1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV1, Science, 272, 1955, 10.1126/science.272.5270.1955 Andrieu, 1995, Viro-immunopathogenesis of HIV disease: implications for therapy, Immunol. Today, 16, 5, 10.1016/0167-5699(95)80062-X Andrieu, 1995, Sustained increases in CD4 cell counts in asymptomatic human immunodeficiency virus type 1-seropositive patients treated with prednisolone for 1 year, J. Infect. Dis., 171, 523, 10.1093/infdis/171.3.523 Aron, 1989, Endocrine complications of the acquired immunodeficiency syndrome, Arch. Intern. Med., 149, 330, 10.1001/archinte.1989.00390020058012 Arora, 1990, Morphine-induced immune alterations in vivo, Cell. Immunol., 126, 343, 10.1016/0008-8749(90)90326-M Baddley, 1993, Acute morphine administration alters the expression of β-adrenergic receptors on splenic lymphocytes, Adv. Biosci., 86, 593 Balter, 1995, Cytokines move from the margins to the spotlight, Science, 268, 205, 10.1126/science.7716511 Bryant, 1988, Morphine pellet-induced immunomodulation in mice: Temporal relationships, J. Pharmacol. Exp. Ther., 245, 913 Bryant, 1991, Role of adrenal cortical activation in the immunosuppressive effects of chronic morphine treatment, Endocrinology, 128, 3253, 10.1210/endo-128-6-3253 Carr, 1993, Alpha adrenergic and mu-2 opioid receptors are involved in morphine-induced suppression of splenocyte natural killer activity, J. Pharmacol. Exp. Ther., 264, 1179 Chaisson, 1992, Immune serum markers and CD4 cell counts in HIV-infected intravenous drug users, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 5, 456 Chaisson, 1995, Race sex, drug abuse, and progression of human immunodeficiency virus disease, New Engl. J. Med., 333, 751, 10.1056/NEJM199509213331202 Chuang, 1993, Modulation of simian AIDS by opioids, Adv. Biosci., 86, 573 Clerici, 1993, A TH1→TH2 switch is a critical step in the etiology of HIV infection, Immunol. Today, 14, 107, 10.1016/0167-5699(93)90208-3 Clerici, 1994, An immunoendocrinological hypothesis of HIV infection, Lancet, 343, 1552, 10.1016/S0140-6736(94)92944-0 Clerici, 1996, Soluble HIV suppressive factors: more than one holy grail?, Immunol. Today, 17, 297, 10.1016/0167-5699(96)80790-0 Concha, 1997, Comparison of neuropsychological test performance between AIDS-free injection drug users and homosexual men, Neuroepidemiology, 16, 78, 10.1159/000109674 Crum, 1996, Alcohol use and T-lymphocyte subsets among injection drug users with HIV-1 infection: A prospective analysis, Alcohol Clin. Exp. Res., 20, 364, 10.1111/j.1530-0277.1996.tb01654.x Dafny, 1983, Interferon modifies morphine withdrawal phenomenon in rodents, Neuropharmacology, 22, 647, 10.1016/0028-3908(83)90157-0 Dalgleish, 1984, The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus, Nature, 312, 763, 10.1038/312763a0 Daniel, 1985, Isolation of T-cell tropic HTLV-III-like retrovirus from macaques, Science, 228, 1201, 10.1126/science.3159089 Dean, 1996, Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene, Science, 273, 1856, 10.1126/science.273.5283.1856 DesJarlais, 1987, Development of AIDS, HIV seroconversion and potential cofactors for T4 cell loss in a cohort of intravenous drug users, AIDS, 1, 105 Donahoe, 1993, Neuroimmunomodulation by opiates: relationship to HIV-1 infection and AIDS, Adv. Neuroimmunol., 3, 31, 10.1016/S0960-5428(06)80057-4 Donahoe, 1985, Morphine depression of T cell E-rosetting: Definition of the process, Fed. Proc., Fed. Am. Soc. Exp. Biol., 44, 95 Donahoe, 1986, Coordinate and independent effects of heroin, cocaine and alcohol abuse on T-cell E-rosette and antigenic marker expression, Clin. Immunol. Immunopathol., 41, 254, 10.1016/0090-1229(86)90109-1 Donahoe, 1987, Mechanistic implications of the findings that opiates and other drugs of abuse moderate T-cell surface receptors and antigenic markers, Ann. N.Y. Acad. Sci., 496, 711, 10.1111/j.1749-6632.1987.tb35834.x Donahoe, 1993, Consequences of opiate-dependency in a monkey model of AIDS, Adv. Exp. Med. Biol., 335, 21, 10.1007/978-1-4615-2980-4_4 Donahoe, R.M., Byrd, L.D., McClure, H.M., Brantley, M., Wenzel, D., Ansari, A.A., Marsteller, F., 1997. Immunological effects of opiate exposure in rhesus monkeys, with emphasis on T cell trafficking effects. Brain Behav. Immunity, (submitted). Dorrucci, 1995, Coinfection of hepatitis C virus with human immunodeficiency virus and progression to AIDS, J. Infect. Dis., 172, 1503, 10.1093/infdis/172.6.1503 Farzadegan H, Levy, D, Astemborski, Saah, A.J., Vlahov, D., Margolick, J.B., Graham, N.M.H., 1996. Effect of gender, race, injecting drug use and disease stage on infectious viral load among IDUs and gay men. Abstract: XI International Conference on AIDS, Vancouver, Canada. Fauci, 1996, Immunopathogenic mechanisms of HIV infection, Ann. Intern. Med., 124, 654, 10.7326/0003-4819-124-7-199604010-00006 Fecho, 1993, Evidence for beta adrenergic receptor involvement in the immunomodulatory effects of morphine, J. Pharmacol. Exp. Ther., 365, 1079 Feng, 1996, HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, protein-coupled receptor, Science, 272, 809, 10.1126/science.272.5263.872 Friedman, H., Klein, T.W., Spector, S., 1993. Drugs of Abuse, Immunity and AIDS. Plenum Press, New York, N.Y. Friedman, 1996, Tuberculosis, AIDS, and death among substance abusers on welfare in New York City, New Engl. J. Med., 334, 828, 10.1056/NEJM199603283341304 Fuchs, 1993, Morphine induces apoptosis in murine thymocytes in vivo but not in vitro: Involvement of both opiate and glucocorticoid receptors, J. Pharmacol. Exp. Ther., 266, 417 Fultz, 1986, Isolation of a T-lymphotropic retrovirus from naturally infected sooty mangabey monkeys (Cercocebus atys), Proc. Natl. Acad. Sci. U.S.A., 83, 5286, 10.1073/pnas.83.14.5286 Galai, N., Taylor, E., Cohn, S., Vlahov, D., 1993. Longitudinal study of immune activation markers among injection drug users using HIV-1 seroconverters. Abstract: IX International Conference on AIDS, Berlin, Germany. Galai, 1995, Changes in markers of disease progression in HIV-1 seroconverters: A comparison between cohorts of injecting drug users and homosexual men, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 8, 66, 10.1097/00042560-199501000-00011 Guan, 1994, Both T cells and macrophages are targets of kappa-opioid-induced immunosuppression, Brain Behav. Immun., 8, 229, 10.1006/brbi.1994.1021 Heath, 1995, Follicular dendritic cells and human immunodeficiency virus infectivity, Nature, 377, 740, 10.1038/377740a0 Heijnen, 1991, Beta-endorphin: cytokine and neuropeptide, Immunol. Rev., 119, 41, 10.1111/j.1600-065X.1991.tb00577.x Hernandez, 1993, Immunosuppression by morphine is mediated by central pathways, J. Pharmacol. Exp. Ther., 267, 1336 Hershow, 1996, An international collaborative study of the effects of coinfection with HTLV-II on HIV-1 disease progression in injection drug users, J. Infect. Dis., 174, 309, 10.1093/infdis/174.2.309 Hogervorst, 1995, Predictors for non- and slow progressors in human immunodeficiency virus (HIV) type 1 infection: low viral RNA copy numbers in serum and maintenance of high HIV-1 p24-specific but not V3-specific antibody levels, J. Infect. Dis., 171, 811, 10.1093/infdis/171.4.811 Jason, 1989, Risk of developing AIDS in HIV-infected cohorts of hemophiliacs and homosexual men, J. Am. Med. Assoc., 262, 3129, 10.1001/jama.1989.03430220050020 Kaslow, 1989, No evidence for a role of alcohol or other psychoactive drugs in accelerating immunodeficiency in HIV-1-positive individuals, J. Am. Med. Assoc., 261, 3424, 10.1001/jama.1989.03420230078030 Kaslow, 1996, Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection, Nature Med., 2, 405, 10.1038/nm0496-405 Klatzman, 1984, T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV, Nature, 312, 767, 10.1038/312767a0 Kroner, 1995, Concordance of haplotype sharing, CD4 decline and AIDS in hemophilic sibling pairs, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 9, 275 Kumar, 1991, Norepinephrine response in early HIV infection, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 4, 782 Kumar, 1993, Abnormal pituitary–adrenocortical response in early HIV-1 infection, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 4, 61 Le Goaster, 1990, ACTH/β-endorphins and ACTH/cortisol ratios as early markers in HIV infection, J. Environ. Pathol. Toxicol. Oncol., 10, 322 Levy, 1990, Changing concepts in HIV infection: challenges for the 1990s, AIDS, 4, 1051, 10.1097/00002030-199011000-00001 Levy, R., Tourani, J.M., Jais, J.P., Andrieu, J.M., 1994. CD4 cell count of asymptomatic patients remains stable under cyclosporin A. Abstract PB0298: X International Conference on AIDS, Yokahama, Japan. Manoff, 1996, The effect of latent Mycobacterium tuberculosis infection on HIV disease progression and HIV RNA load among injecting drug users, J. Infect. Dis., 174, 299, 10.1093/infdis/174.2.299 Margolick, 1992, Changes in T-lymphocyte subsets in intravenous drug users with HIV-1 infection, J. Am. Med. Assoc., 267, 1631, 10.1001/jama.1992.03480120069035 Margolick, 1994, Direct comparison of the relationship between clinical outcome and change in CD4+ lymphocytes in human immunodeficiency virus-positive homosexual men and injecting drug users, Arch. Intern. Med., 154, 869, 10.1001/archinte.1994.00420080065006 Margolick, 1995, Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. The multicenter AIDS cohort study, Nature Med., 1, 674, 10.1038/nm0795-674 Margolick, 1996, Relationship between infectious cell-associated human immunodeficiency virus type 1 load, T lymphocyte subsets, and stage of infection in homosexual men, J. Infect. Dis., 173, 468, 10.1093/infdis/173.2.468 McDonough, 1980, Alteration of T and null lymphocyte frequencies in the peripheral blood on human opiate addicts: in vivo evidence of opiate receptor sites on T lymphocytes, J. Immunol., 125, 2539, 10.4049/jimmunol.125.6.2539 Meisheri, 1978, Influence of immune stimulation and suppression of on morphine physical dependence and tolerance, Res. Commun. Chem. Pathol. Pharmacol., 19, 85 Mellors, 1996, Prognosis in HIV-1 infection predicted by the quantity of virus in plasma, Science, 272, 1167, 10.1126/science.272.5265.1167 Membrano, 1987, Adrenocortical function in acquired immunodeficiency syndrome, J. Clin. Endocrinol. Metab., 65, 482, 10.1210/jcem-65-3-482 Merenich, 1990, Evidence of endocrine involvement early in the course of human immunodeficiency virus infection, J. Clin. Endocrinol. Metab., 70, 566, 10.1210/jcem-70-3-566 Meyaard, 1996, Single-cell analysis of IL-4 and IFN-γ production by T cells from HIV-infected individuals, J. Immunol., 157, 2712, 10.4049/jimmunol.157.6.2712 Mientjes, 1993, Progression of HIV infection among injecting drug users: Indications for a lower rate of progression among those who have frequently borrowed injecting equipment, AIDS, 7, 1363, 10.1097/00002030-199310000-00010 Molitor, 1992, Chronic morphine administration impairs cell-mediated immune responses in swine, J. Pharmacol. Exp. Ther., 260, 581 Montella, 1992, T-lymphocyte subsets in intravenous drug users with HIV-1 infection [Letter], J. Am. Med. Assoc., 268, 2516, 10.1001/jama.1992.03490180047019 Munoz, 1989, Predictors of decline in CD4 lymphocytes in a cohort of homosexual men infected with human immunodeficiency virus, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 1, 396 Munoz, 1992, Prognostic indicators for development of AIDS among intravenous drug users, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 5, 694 Murphey-Corb, 1989, A formalin-inactivated whole SIV vaccine confers protection in macaques, Science, 246, 1293, 10.1126/science.2555923 Nott, 1995, Psychology, immunology, and HIV, Psychoneuroendocrinology, 20, 451, 10.1016/0306-4530(94)00080-T Nowak, 1995, How HIV defeats the immune system, Sci. Am., 273, 58, 10.1038/scientificamerican0895-58 Panteleo, 1995, Pathogenic insights from studies of lymphoid tissue from HIV-infected individuals, J. Acquired Immune Defic. Syndr. Hum. Retrovirol., 10, S6 Panteleo, 1997, The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia, Proc. Natl. Acad. Sci. U.S.A., 94, 254, 10.1073/pnas.94.1.254 Pelletier, 1996, Research commentary: AIDS is not caused by the extreme genetic variability of HIV, J. NIH Res., 8, 45 Peterson, 1987, Opioid-mediated suppression of cultured peripheral blood mononuclear cell respiratory burst activity, J. Immunol., 138, 3907, 10.4049/jimmunol.138.11.3907 Peterson, 1990, Morphine promotes the growth of HIV-1 in human peripheral blood mononuclear cell cocultures, AIDS, 4, 869, 10.1097/00002030-199009000-00006 Peterson, 1991, Cocaine potentiates HIV-1 replication in human peripheral blood mononuclear cell cocultures, J. Immunol., 146, 81, 10.4049/jimmunol.146.1.81 Pezzotti, 1994, Decremento dei linfociti CD4+ nell'infezione da HIV: uno studio longitudinale su 941 individui con data di sieroconversione nota, Articoli Originali, 5, 93 Pezzotti, 1996, HIV exposure category and age in the progression to AIDS in a longitudinal study of 1199 individuals with known seroconversion rates, Br. Med. J., 310, 941 Plotnikoff, N.P., Faith, R.E., Murgo, A.J., Good, R.A., 1986. Enkephalins and Endorphins. Stress and the Immune Axis. Plenum Press, New York, N.Y. Rabin, 1995, Altered representation of naive and memory CD8 T cell subsets in HIV-infected children, J. Clin. Invest., 95, 2054, 10.1172/JCI117891 Rezza, 1990, Risk of AIDS in HIV seroconverters: A comparison between intravenous drug users and homosexual males, Eur. J. Epidemiol., 6, 99, 10.1007/BF00155560 Risdhal, 1993, Effects of morphine dependence on the pathogenesis of swine herpes virus infection, J. Infect. Dis., 167, 1281, 10.1093/infdis/167.6.1281 Roederer, 1995, CD8 naive T cell counts decrease progressively in HIV-infected adults, J. Clin. Invest., 95, 2061, 10.1172/JCI117892 Rothenberg, 1986, Survival with the acquired immunodeficiency syndrome: experience with 5833 cases in New York City, New Engl. J. Med., 317, 1297, 10.1056/NEJM198711193172101 Saksela, 1994, Human immunodeficiency virus type 1 mRNA expression in peripheral blood cells predicts disease progression independently of the numbers of CD4+ lymphocytes, Proc. Natl. Acad. Sci. U.S.A., 91, 1104, 10.1073/pnas.91.3.1104 Samuels, 1992, Measurement of risk behaviors among intravenous drug users, Br. J. Addiction, 87, 417, 10.1111/j.1360-0443.1992.tb01942.x Sapira, 1968, The narcotic addict as a medical patient, Am. J. Med., 45, 555, 10.1016/0002-9343(68)90172-1 Schnittman, 1990, Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: Evidence for a role in the selective T-cell functional defects observed in infected individuals, Proc. Natl. Acad. Sci. U.S.A., 87, 6058, 10.1073/pnas.87.16.6058 Selnes, 1992, HIV-1 infection and intravenous drug use: longitudinal neurophysical evaluation of asymptomatic patients, Neurology, 42, 1924, 10.1212/WNL.42.10.1924 Selwyn, 1992, Clinical manifestations and predictors of disease progression in drug users with human immunodeficiency virus infection, New Engl. J. Med., 327, 1697, 10.1056/NEJM199212103272401 Shavit, 1986, Involvement of brain opiate receptors in the immune-suppressive effects of morphine, Proc. Natl. Acad. Sci. U.S.A., 83, 7114, 10.1073/pnas.83.18.7114 Shavit, 1986, Effects of footshock stress and morphine on natural killer lymphocytes in rats: studies of tolerance and cross tolerance, Brain Res., 372, 382, 10.1016/0006-8993(86)91149-2 Spijkerman, 1995, Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men, AIDS, 9, 1085, 10.1097/00002030-199509000-00016 Spijkerman, 1996, Differences in progression to AIDS between injection drug users and homosexual men with documented dates of seroconversion, Epidemiology, 7, 571, 10.1097/00001648-199611000-00002 Tross, 1988, Psychological distress and neuropsychological complications of HIV infection and AIDS, Am. Psychologist, 43, 929, 10.1037/0003-066X.43.11.929 Tubaro, 1983, Effect of morphine on resistance to infection, J. Infect. Dis., 148, 656, 10.1093/infdis/148.4.656 Tubaro, 1985, Morphine and methadone, impact on human phagocytic physiology, Int. J. Immunopharmacol., 7, 865, 10.1016/0192-0561(85)90049-9 Veyries, 1995, Effects of morphine on the pathogenesis of murine Friend retrovirus infection, J. Pharmacol. Exp. Ther., 272, 498 Vlahov, 1991, The ALIVE Study: a longitudinal study of HIV-1 infection in intravenous drug users: description of methods and characteristics of participants, NIDA Res. Monogr. Ser., 109, 75 Vlahov, D., Munoz, A., Saah, A.J., Solomon, L., Palenecik, J., Margolick, J. B., Astembroski, J., Bareta, J., Nelson, K.E., 1992. Prognostic indicators for development of AIDS in two cohorts. Abstract: VIIIth International Conference on AIDS, Amsterdam, Netherlands. Vlahov D., Hoover D.R., Astemborski J., Fuller, C., Graham, N.M.H., Margolick, J.B., 1996. Continuous vs. intermittent patterns of injection drug use, episodes of drug withdrawal or overdose do not predict HIV related immunosuppression in injection drug users. Abstract: XI International Conference on AIDS, Vancouver, Canada. Westby, 1996, The role of host immune responses in determining the outcome of HIV infection, Immunol. Today, 17, 120, 10.1016/0167-5699(96)80603-7 Wolinsky, 1996, Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection, Science, 272, 537, 10.1126/science.272.5261.537 Wybran, 1979, Suggestive evidence for receptors for morphine and methionine-enkephalin on normal human blood T lymphocytes, J. Immunol., 123, 1068, 10.4049/jimmunol.123.3.1068