The accuracy of 1- and 3-mm slices in coronary calcium scoring using multi-slice CT in vitro and in vivo
Tóm tắt
The accuracy of coronary calcium scoring using 16-row MSCT comparing 1- and 3-mm slices was assessed. A thorax phantom with calcium cylinder inserts was scanned applying a non-enhanced retrospectively ECG-gated examination protocol: collimation 12×0.75 mm; 120 kV; 133 mAseff. Thirty-eight patients were examined using the same scan protocol. Image reconstruction was performed with an effective slice thickness of 3 and 1 mm. The volume score, calcium mass and Agatston score were determined. Image noise was measured in both studies. The volume score and calcium mass varied less than the Agatston score. The overall measured calcium mass compared to the actual calcium mass revealed a relative difference of +2.0% for 1-mm slices and −1.2% for 3-mm slices. Due to increased image noise in thinner slices in the patient study (26.1 HU), overall calcium scoring with a scoring threshold of 130 HU was not feasible. Interlesion comparison showed significantly higher scoring results for thinner slices (all P<0.001). A similar accuracy comparing calcium scoring results of 1- and 3-mm slices was shown in the phantom study; therefore, the potentially necessary increase of the patient's dose in order to achieve assessable 1-mm slices with an acceptable image-to-noise-ratio appears not to be justified.
Tài liệu tham khảo
Frink RJ, Achor RW, Brown AL Jr, Kincaid OW, Brandenburg RO (1970) Significance of calcification of the coronary arteries. Am J Cardiol 26:241–247
McCarthy JH, Palmer FJ (1974) Incidence and significance of coronary artery calcification. Br Heart J 36:499–506
Rifkin RD, Parisi AF, Folland E (1979) Coronary calcification in the diagnosis of coronary artery disease. Am J Cardiol 44:141–147
Heussel CP, Voigtlaender T, Kauczor H, Braun M, Meyer J, Thelen M (1998) Detection of coronary artery calcifications predicting coronary heart disease: comparison of fluoroscopy and spiral CT. Eur Radiol 8:1016–1024
Rumberger JA, Sheedy PF, Breen JF, Schwartz RS (1997) Electron beam computed tomographic coronary calcium score cutpoints and severity of associated angiographic lumen stenosis. J Am Coll Cardiol 29:1542–1548
Guerci AD, Spadaro LA, Goodman KJ et al (1998) Comparison of electron beam computed tomography scanning and conventional risk factor assessment for the prediction of angiographic coronary artery disease. J Am Coll Cardiol 32:673–679
Rumberger JA, Brundage BH, Rader DJ, Kondos G (1999) Electron beam computed tomographic coronary calcium scanning: a review and guidelines for use in asymptomatic persons. Mayo Clin Proc 74:243–252
Rumberger JA, Simons DB, Fitzpatrick LA, Sheedy PF, Schwartz RS (1995) Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. Circulation 92:2157–2162
Agatston AS, Janowitz WR, Hildner FJ, Zusmer NR, Viamonte M Jr, Detrano R (1990) Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15:827–832
Becker CR, Kleffel T, Crispin A et al (2001) Coronary artery calcium measurement: agreement of multirow detector and electron beam CT. Am J Roentgenol 176:1295–1298
Carr JJ, Crouse JR 3rd, Goff DC Jr, D’Agostino RB Jr, Peterson NP, Burke GL (2000) Evaluation of subsecond gated helical CT for quantification of coronary artery calcium and comparison with electron beam CT. Am J Roentgenol 174:915–921
Becker CR, Jakobs TF, Aydemir S et al (2000) Helical and single-slice conventional CT versus electron beam CT for the quantification of coronary artery calcification. Am J Roentgenol 174:543–547
Kopp AF, Ohnesorge B, Becker C et al (2002) Reproducibility and accuracy of coronary calcium measurements with multi-detector row versus electron-beam CT. Radiology 225:113–119
Horiguchi J, Nakanishi T, Ito K (2001) Quantification of coronary artery calcium using multidetector CT and a retrospective ECG-gating reconstruction algorithm. Am J Roentgenol 177:1429–1435
Mahnken AH, Wildberger JE, Sinha AM et al (2002) Variation of the coronary calcium score depending on image reconstruction interval and scoring algorithm. Invest Radiol 37:496–502
Sanz J, Rius T, Kuschnir P et al (2005) The importance of end-systole for optimal reconstruction protocol of coronary angiography with 16-slice multidetector computed tomography. Invest Radiol 40:155–163
Ulzheimer S, Kalender WA (2003) Assessment of calcium scoring performance in cardiac computed tomography. Eur Radiol 13:484–497
Janssen CH, Kuijpers D, Vliegenthart R, Overbosch J, van Dijkman PR, Zijlstra F, Oudkerk M (2005) Coronary artery calcification score by multislice computed tomography predicts the outcome of dobutamine cardiovascular magnetic resonance imaging. Eur Radiol 15:1128–1134
van Ooijen PM, Vliegenthart R, Witteman JC, Oudkerk M (2005) Influence of scoring parameter settings on Agatston and volume scores for coronary calcification. Eur Radiol 15:102–110
Mahnken AH, Muhlenbruch G, Koos R et al (2005) Influence of a small field-of-view size on the detection of coronary artery calcifications with MSCT: in vitro and in vivo study. Eur Radiol Aug 20:10.1007/s00330-005-2881-z
Yoon HC, Greaser LE 3rd, Mather R, Sinha S, McNitt-Gray MF, Goldin JG (1997) Coronary artery calcium: alternate methods for accurate and reproducible quantitation. Acad Radiol 4:666–673
Callister TQ, Cooil B, Raya SP, Lippolis NJ, Russo DJ, Raggi P (1998) Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method. Radiology 208:807–814
Brown SJ, Hayball MP, Coulden RA (2000) Impact of motion artifact on the measurement of coronary calcium score. Br J Radiol 73:956–962
Vliegenthart R, Song B, Hofman A, Witteman JC, Oudkerk M (2003) Coronary calcification at electron-beam CT: effect of section thickness on calcium scoring in vitro and in vivo. Radiology 229:520–525
Mao S, Child J, Carson S, Liu SC, Oudiz RJ, Budoff MJ (2003) Sensitivity to detect small coronary artery calcium lesions with varying slice thickness using electron beam tomography. Invest Radiol 38:183–187
Hong C, Becker CR, Schoepf UJ, Ohnesorge B, Bruening R, Reiser MF (2002) Coronary artery calcium: absolute quantification in nonenhanced and contrast-enhanced multi-detector row CT studies. Radiology 223:474–480
Muhlenbruch G, Thomas C, Wildberger JE et al (2005) Effect of varying slice thickness on coronary calcium scoring with multislice computed tomography in vitro and in vivo. Invest Radiol 40:695–699
Hong C, Bae KT, Pilgram TK, Suh J, Bradley D (2002) Coronary artery calcium measurement with multi-detector row CT: in vitro assessment of effect of radiation dose. Radiology 225:901–906
Stamm G, Nagel HD (2002) CT-expo-a novel program for dose evaluation in CT. Rofo 174:1570–1576
Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310
Lu B, Budoff MJ, Zhuang N et al (2002) Causes of interscan variability of coronary artery calcium measurements at electron-beam CT. Acad Radiol 9:654–661
Cademartiri F, Mollet NR, Runza G, Bruining N, Hamers R, Somers P, Knaapen M, Verheye S, Midiri M, Krestin GP, de Feyter PJ (2005) Influence of intracoronary attenuation on coronary plaque measurements using multislice computed tomography: observations in an ex vivo model of coronary computed tomography angiography. Eur Radiol 15:1426–1431
Muhlenbruch G, Wildberger JE, Koos R, Das M, Flohr TG, Niethammer M, Weiss C, Gunther RW, Mahnken AH (2005) Coronary calcium scoring using 16-row multislice computed tomography: nonenhanced versus contrast-enhanced studies in vitro and in vivo. Invest Radiol 40:148–154
Mahnken AH, Wildberger JE, Simon J et al (2003) Detection of coronary calcifications: feasibility of dose reduction with a body weight-adapted examination protocol. Am J Roentgenol 181:533–538
Hong C, Bae KT, Pilgram TK (2003) Coronary artery calcium: accuracy and reproducibility of measurements with multi-detector row CT-assessment of effects of different thresholds and quantification methods. Radiology 227:795–801
Callister TQ, Raggi P, Cooil B, Lippolis NJ, Russo DJ (1998) Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. N Engl J Med 339:1972–1978
Bielak LF, Sheedy PF 2nd, Peyser PA (2001) Coronary artery calcification measured at electron-beam CT: agreement in dual scan runs and change over time. Radiology 218:224–229