Acute gastric mucosal injury induced by toxins from Tityus serrulatus scorpion venom: a novel experimental model in the rat

Toxicon - Tập 29 - Trang 1395-1401 - 1991
J.R. Cunha-Melo1, N.H. Toppa2, P. Martins1, C.N. Colares1, Y.S. Castro1, L. Freire-Maia3
1Department of Surgery, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
2Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
3Department of Pharmacology, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil

Tài liệu tham khảo

Ader, 1964, Gastric erosions in the rat, Science, 145, 406, 10.1126/science.145.3630.406 Ader, 1971, Experimentally induced gastric lesions, Adv. Psychosom. Med., 6, 1, 10.1159/000391679 Anson, 1938, The stimulation of pepsin, trypsin, papain and cathepsin with hemoglobin, J. Gen. Physiol., 22, 79, 10.1085/jgp.22.1.79 Berstadt, 1970, A modified hemoglobin substrate method for stimulation of pepsin in gastric juice, Scand. J. Gastroenterol., 5, 343, 10.1080/00365521.1970.12096601 Brodie, 1963, Production of gastric hemorrhage in rats by multiple stresses, Proc. Soc. Exp. Biol. Med., 113, 998, 10.3181/00379727-113-28555 Buchel, 1966, Influence de la temperature ambiente sur la production d'ulceres de containt chez le rat, C. R. Soc. Biol., 160, 1817 Carmichael, 1978, Cimetidine and prostaglandin: evidence for different modes of action on the rat gastric mucosa, Gastroenterology, 74, 1229, 10.1016/0016-5085(78)90697-2 Chaudhury, 1980, Prevention by mild irritants of gastric necrosis produced in rats by sodium taurocholate, Dig. Dis. Sci., 25, 830, 10.1007/BF01338524 Cheney, 1974, Ketamine-induced stress ulcers in the rat, Anesthesiology, 40, 531, 10.1097/00000542-197406000-00004 Cunha-Melo, 1983, Effects of purified scorpion toxin (tityustoxin) on gastric secretion in the rat, Toxicon, 21, 843, 10.1016/0041-0101(83)90073-9 Cunha-Melo, 1987, Effect of scorpion toxin on gastric histamine and acetylcholine content in the rat, Brazilian J. Med. Biol. Res., 20, 393 Desmarel, 1960, A propos de l'action de meprobamate sur les ulcères gastriques expérimentaux obtenus par le méthode d'électrization intermittente chez le rat blanc, C. R. Soc. Biol., 154, 450 Diniz, 1973, Liberação de acetilcolina do tecido nervoso pela tityustoxina (TsTX) purificada do veneno de Tityus serrulatus, Acta Physiol. Latino Am., 23, 313 Freire-Maia, 1983, Neurotoxins as tools for physiological investigation, The Physiologist, 26, 381 Freire-Maia, 1989, Pathophysiology and treatment of scorpion poisoning, 139 Freire-Maia, 1976, Cholinergic and adrenergic effects of tityustoxin, Gen. Pharmacol., 7, 115, 10.1016/0306-3623(76)90046-X Gaetani, 1972, Action of L-Dopa, norepinephrine and amantidine on ulcers caused by reserpine in the rat, Digestion, 7, 302, 10.1159/000197288 Glavin, 1976, Role of gastric acid in restraint-induced ulceration in the rat, Physiol. Behav., 17, 777, 10.1016/0031-9384(76)90039-1 Goldman, 1968, Pathogenesis of acute gastric ulcers, Am. J. Pathol., 52, 227 Gomez, 1966, Separation of toxic components from the Brazilian scorpion Tityus serrulatus, Mem. Inst. Butantan, 33, 899 Gonzaga, 1979, Gastric secretion induced by scorpion toxin, Toxicon, 17, 316, 10.1016/0041-0101(79)90222-8 Hase, 1973, Microvascular changes of gastric mucosa in the development of stress ulcer in rats, Gastroenterology, 65, 224, 10.1016/S0016-5085(19)33103-8 Karppanen, 1976, Ethanol, indomethacin and gastric acid secretion in the rat, Eur. J. Pharmacol., 38, 221, 10.1016/0014-2999(76)90320-4 Lacy, 1982, Microscopic analysis of ethanol damage to rat gastric mucosa after treatment with a prostaglandin, Gastroenterology, 83, 619, 10.1016/S0016-5085(82)80198-4 Levrat, 1959, Experimental ulcers produced in rats by modification of environment, Gastroenterology, 37, 421, 10.1016/S0016-5085(19)35385-5 Manning, 1978, Microscopic examination of the activity-stress ulcer in the rat, Physiol. Behav., 21, 269, 10.1016/0031-9384(78)90052-5 Mikhail, 1966, A simplified method of inducing stomach ulcers, J. Psychosom. Res., 9, 343, 10.1016/0022-3999(66)90004-3 Morris, 1981, The roles of ethanol and of acid in the production of gastric mucosa erosions in rat, Virchows Arch [Cell Pathol.], 38, 23, 10.1007/BF02892800 Mullane, 1973, Hypoxia and stress ulcer formation in the rat, Surgery, 74, 326 Mullane, 1973, Metabolic acidosis, stress and gastric lesions in the rat, Arch. Surg., 107, 456, 10.1001/archsurg.1973.01350210086022 Mullane, 1974, Starvation, glucose and stress ulcers in the rat, Arch. Surg., 109, 416, 10.1001/archsurg.1974.01360030068018 Possani, 1977, Purification and properties of mammalian toxins from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello, Archs Biochem. Biophys., 180, 394, 10.1016/0003-9861(77)90053-4 Rasche, 1983, Vitamin A pretreatment of stress ulcers in the rat, Arch. Surg., 106, 320, 10.1001/archsurg.1973.01350150054015 Rosenberg, 1967, Production of gastric lesions in rats by combined cold and electric stress, Am. J. Digest. Dis., 12, 1140, 10.1007/BF02233881 Salay, 1966, Ulcerogenic action of chronic neurogenic stimulation in the rat, Acta Physiol. Scand., 22, 81 Sampaio, 1983, Isolation and characterization of toxic proteins from the venom of the Brazilian scorpion Tityus serrulatus, Toxicon, 21, 265, 10.1016/0041-0101(83)90011-9 Sawrey, 1956, An experimental method of producing gastric ulcers, J. Comp. Physiol. Psychol., 49, 269, 10.1037/h0040634 Senay, 1967, Synergism between cold and restraint for rapid production of stress ulcers in rats, Proc. Soc. Exp. Biol. Med., 124, 1221, 10.3181/00379727-124-31970 Sethbharki, 1970, Gastric mucosal ulceration following vasoactive agents, Dig. Dis. Sci., 15, 261, 10.1007/BF02233458 Shay, 1945, A simple method for the uniform production of gastric ulceration in the rat, Gastroenterology, 5, 43 Silen, 1988, Experimental models of gastric ulceration and injury, Am. J. Physiol., 255, G395 Singer, 1913, The production of ulcer of the stomach in the rat, Lancet, 2, 279, 10.1016/S0140-6736(01)76512-9 Szabo, 1985, A quantitative method for assessing the extent of experimental gastric erosions and ulcers, J. Pharmacol. Meth., 13, 59, 10.1016/0160-5402(85)90068-3 Toledo, 1976, Purification and partial characterization of a second toxin from the scorpion Tityus serrulatus, Comp. Biochem. Physiol., 55B, 249