An official systematic review of the European Respiratory Society/American Thoracic Society: measurement properties of field walking tests in chronic respiratory disease

European Respiratory Journal - Tập 44 Số 6 - Trang 1447-1478 - 2014
Sally Singh1, Milo A. Puhan1, Vasileios Andrianopoulos1, Nídia Aparecida Hernandes1, Katy Mitchell1, Catherine J. Hill1, Annemarie L. Lee1, Carlos Augusto Camillo1, Thierry Troosters1, Martijn A. Spruit1, Brian Carlin1, Jack Wanger1, Véronique Pepin1, Didier Saey1, Fábio Pitta1, David A. Kaminsky1, Meredith C. McCormack1, Neil MacIntyre1, Bruce H. Culver1, Frank C. Sciurba1, S M Revill1, Veronica Delafosse1, Anne E. Holland1
1For a full list of the authors' affiliations please refer to the Acknowledgements.

Tóm tắt

This systematic review examined the measurement properties of the 6-min walk test (6MWT), incremental shuttle walk test (ISWT) and endurance shuttle walk test (ESWT) in adults with chronic respiratory disease.Studies that report the evaluation or use of the 6MWT, ISWT or ESWT were included. We searched electronic databases for studies published between January 2000 and September 2013.The 6-min walking distance (6MWD) is a reliable measure (intra-class correlation coefficients ranged from 0.82 to 0.99 in seven studies). There is a learning effect, with greater distance walked on the second test (pooled mean improvement of 26 m in 13 studies). Reliability was similar for ISWT and ESWT, with a learning effect also evident for ISWT (pooled mean improvement of 20 m in six studies). The 6MWD correlates more strongly with peak work capacity (r=0.59–0.93) and physical activity (r=0.40–0.85) than with respiratory function (r=0.10–0.59). Methodological factors affecting 6MWD include track length, encouragement, supplemental oxygen and walking aids. Supplemental oxygen also affects ISWT and ESWT performance. Responsiveness was moderate to high for all tests, with greater responsiveness to interventions that included exercise training.The findings of this review demonstrate that the 6MWT, ISWT and ESWT are robust tests of functional exercise capacity in adults with chronic respiratory disease.

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Tài liệu tham khảo

10.1183/09031936.00150314

10.1164/ajrccm.166.1.at1102

10.1136/thx.39.11.818

10.1136/thx.47.10.781

10.1378/chest.108.2.452

10.1164/rccm.200203-166OC

10.1053/rmed.2002.1462

10.1183/09031936.00142010

10.1016/0021-9681(85)90035-9

10.1053/rmed.2002.1363

10.1111/j.1440-1843.2010.01744.x

10.1164/rccm.200405-578OC

10.1111/j.1440-1843.2010.01841.x

Jorquera Guillén, 1999, Reproductibilidad del test de la marcha (walking test) en pacientes afectos de fibrosis quistica [Reproducibility of the walking test in patients with cystic fibrosis], An Esp Pediatr, 51, 475

Ziegler, 2010, Repeatability of the 6-minute walk test in adolescents and adults with cystic fibrosis, Respir Care, 55, 1020

10.1378/chest.123.5.1401

10.1097/00008483-200003000-00001

Rodrigues, 2004, Teste de caminhada de seis minutos: estudo do efeito do aprendizado em portadores de doença pulmonar obstrutiva crônica [Six minutes walk test: study of the effect of learning in chronic obstructive pulmonary disease patients], J Bras Pneumol, 30, 121, 10.1590/S1806-37132004000200008

10.1093/ageing/25.1.12

10.1164/ajrccm.160.5.9808139

10.1183/09031936.02.02092001

10.1097/PHM.0b013e3181583e66

10.1136/ard.2006.054866

10.1111/j.1440-1843.2012.02133.x

10.1002/(SICI)1099-0496(199608)22:2<85::AID-PPUL1>3.0.CO;2-I

10.1002/ppul.20308

Mandrusiak, 2009, Functional capacity tests in young people with cystic fibrosis, N Z J Physiother, 37, 13

10.1159/000220343

Borg, 1982, Psychophysical bases of perceived exertion, Med Sci Sports Exerc, 14, 377, 10.1249/00005768-198205000-00012

10.1136/thx.49.5.468

10.1053/rmed.2001.1115

10.1067/mhl.2002.127941

10.1378/chest.123.5.1408

10.2220/biomedres.24.309

10.1378/chest.126.3.766

Starobin, 2006, Assessment of functional capacity in patients with chronic obstructive pulmonary diesease: correlation between cardiopulmonary exercise, 6 minute walk and 15 step exercise oximetry test, Isr Med Assoc J, 8, 460

10.1016/j.apmr.2008.01.020

10.1111/j.1440-1843.2008.01355.x

Díaz, 2010, Prueba de marcha de 6 min y ejercicio maximo en cicloergometro en la enfermedad pulmonar obstructiva cronica, ¿son sus demandas fisiologicas equivalentes? [Six-minute-walk test and maximum exercise test in cycloergometer in chronic obstructive pulmonary disease. Are the physiological demands equivalent?], Arch Bronconeumol, 46, 294, 10.1016/j.arbres.2010.02.006

10.3109/15412555.2012.655866

Holland, 2010, The 6-minute walk test elicits high but submaximal cardiorespiratory responses in interstitial lung disease, Am J Respir Crit Care Med, 181, A2968

10.1186/1471-2466-13-1

10.1164/ajrccm.161.2.9906015

10.1183/09031936.05.00031505

10.1111/j.1445-5994.2011.02501.x

10.1164/rccm.201203-0372OC

10.1186/1471-2466-10-31

10.1111/j.1440-1843.2011.02089.x

Blanco, 2010, Consumo maximo de oxigeno durante la prueba de marcha de 6 minutos en la enfermedad pulmonar intersticial difusa y en la hipertension pulmonar [Peak oxygen uptake during the six-minute walk test in diffuse interstitial lung disease and pulmonary hypertension], Arch Bronconeumol, 46, 122, 10.1016/j.arbres.2009.12.005

10.1136/thx.48.1.33

10.1080/15412550801941265

Brasil Santos, 2009, Correlação dos graus de obstrução na DPOC com lactato e teste de caminhada de seis minutos [Correlation of levels of obstruction in COPD with lactate and six-minute walk test], Rev Port Pneumol, 15, 11, 10.1016/S0873-2159(15)30106-9

10.3109/15412555.2011.650240

Chen, 2012, Relationship between 6-minute walk test and pulmonary function test in stable chronic obstructive pulmonary disease with different severities, Chin Med J, 125, 3053

10.1371/journal.pone.0037329

10.1111/j.1445-5994.2012.02771.x

10.3109/15412555.2011.647130

10.1016/j.rmr.2012.08.004

Chetta, 2001, Relationship between outcome measures of six-minute walk test and baseline lung function in patients with interstitial lung disease, Sarcoidosis Vasc Diffuse Lung Dis, 18, 170

10.3899/jrheum.080447

10.1164/rccm.201109-1618OC

10.1164/rccm.201007-1179OC

10.1016/j.rmed.2012.07.013

10.3899/jrheum.081221

Deuschle, 2011, Six-minute walk distance as a marker for disability and complaints in patients with systemic sclerosis, Clin Exp Rheumatol, 29, S53

10.1378/chest.11-0870

10.1590/S1806-37132007000300006

10.1016/j.jtcvs.2006.10.020

10.1016/j.rmed.2012.02.015

Cuomo, 2012, Relationship of the 6-min walking test and quality of life, Rheumatology, 51, ii103

10.1590/S0066-782X2012005000079

10.1164/rccm.200407-855OC

10.1164/rccm.200812-1873OC

Hernandes, 2009, Perfil do nivel de atividade fisica na vida diaria de pacientes portadores de DPOC no Brasil [Profile of the level of physical activity in the daily lives of patients with COPD in Brazil], J Bras Pneumol, 35, 949, 10.1590/S1806-37132009001000002

10.1378/chest.11-0298

10.3109/15412555.2012.705364

10.1183/09031936.00091607

10.1371/journal.pone.0027993

10.1378/chest.12-0150

10.1016/j.rmed.2012.01.003

10.1097/HCR.0b013e3182839293

10.1378/chest.06-0630

10.1164/ajrccm.155.4.9105067

10.1016/j.apmr.2009.10.017

10.1016/j.rmed.2009.04.024

de Almeida, 2009, Hallway versus treadmill 6-minute-walk tests in patients with chronic obstructive pulmonary disease, Respir Care, 54, 1712

10.1016/S0003-9993(03)00011-X

10.1378/chest.07-2823

10.1016/S1836-9553(13)70181-4

10.1097/00008483-200603000-00011

10.1097/00008483-199601000-00008

10.1378/chest.126.4.1102

10.1093/ageing/27.6.703

10.1378/chest.122.1.56

10.1378/chest.11-1076

10.1136/thx.43.12.965

10.1378/chest.122.2.457

10.1183/09031936.97.10061278

10.1378/chest.120.2.437

Woodcock, 1981, Oxygen relieves breathlessness in “pink puffers”, Lancet, 1, 907, 10.1016/S0140-6736(81)91612-3

10.1164/ajrccm.152.5.7582304

10.1371/journal.pone.0023770

10.1378/chest.13-0287

10.1136/thx.2010.146159

10.1164/rccm.200507-1037OC

10.1136/thx.2006.065540

10.1183/09031936.00119007

10.1164/ajrccm.161.6.9905045

10.1378/chest.111.3.550

10.1378/chest.118.3.697

10.1183/09031936.03.00034603

10.1183/09031936.00071506

10.1378/chest.07-2050

10.1016/j.rmed.2006.06.017

10.1378/chest.08-0520

10.1183/09031936.00104507

10.1016/S0140-6736(09)61301-5

10.1097/HCR.0b013e3181c565e4

10.3109/15412555.2011.589870

10.1016/j.jamda.2011.06.009

10.4187/respcare.01440

Tertemiz, 2012, Kronik obstruktif akciger hastaliginda mortalite ve mortaliteyi etkileyen faktorler [Mortality and factors affecting mortality in chronic obstructive pulmonary disease], Tuberk Toraks, 60, 114, 10.5578/tt.2889

10.1164/rccm.200302-219OC

10.1164/rccm.200604-520OC

10.1016/j.rmed.2006.02.004

10.1183/09031936.00165207

10.1016/j.rmed.2008.07.022

10.1378/chest.09-0211

10.1016/j.rmed.2013.04.002

10.1183/09031936.01.17406470

10.1016/j.rmed.2009.01.017

10.1183/09031936.00155009

10.1161/CIRCULATIONAHA.109.898122

10.1164/rccm.201105-0848OC

10.1183/09031936.00196611

10.1183/09031936.00092311

10.1007/s00408-011-9350-z

10.1159/000109662

10.1111/j.1600-6143.2008.02264.x

10.1016/j.healun.2008.03.017

10.1016/j.rmed.2009.07.011

10.1016/j.jecm.2011.11.008

Inal-Ince, 2005, Functional capacity in severe chronic obstructive pulmonary disease, Saudi Med J, 26, 84

10.1016/j.rmed.2009.12.007

10.1164/ajrccm.163.7.2001071

10.1378/chest.09-0410

10.1016/S0300-2896(02)75167-3

Ilgin, 2010, Gender effect on the use of modified Borg and visual analog scales in the evaluation of dyspnea in chronic obstructive pulmonary disease, Pak J Med Sci, 26, 76

10.1016/j.rmed.2006.06.030

10.1378/chest.130.5.1496

10.1186/1477-7525-10-67

10.1016/j.apmr.2010.07.228

10.1186/1465-9921-12-3

10.1016/S0954-6111(98)90517-0

10.1378/chest.114.4.958

10.1111/j.1440-1843.2005.00729.x

10.1136/thx.2009.118109

Mangueira, 2009, Correlação entre parâmetros clínicos e qualidade de vida relacionada à saúde em mulheres com DPOC [Correlation between clinical parameters and health-related quality of life in women with COPD], J Bras Pneumol, 35, 248, 10.1590/S1806-37132009000300009

10.1046/j.1365-2648.2003.02878.x

10.1183/09031936.06.00042705

10.1111/j.1440-1843.2010.01877.x

10.1016/j.ahj.2012.01.023

10.1111/j.1445-5994.2010.02169.x

10.1159/000332833

10.1164/rccm.200604-488OC

10.3346/jkms.2011.26.3.372

10.1177/1479972311407355

10.4187/respcare.02494

Modrykamien, 2010, Echocardiography, 6-minute walk distance, and distance-saturation product as predictors of pulmonary arterial hypertension in idiopathic pulmonary fibrosis, Respir Care, 55, 584

10.1186/1471-2466-10-42

10.1590/S1807-59322010000900005

Teixeira, 2006, O trabalho de caminhada dos seis minutos não se correlaciona com o grau de obstrução do fluxo aéreo em doentes portadores de doença pulmonar obstrutiva crônica [Six-minute walk work is not correlated to the degree of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD)], Rev Port Pneumol, 12, 241, 10.1016/S0873-2159(15)30435-9

10.1183/09031936.00194909

10.1590/S1806-37132011000500007

10.1139/h11-075

10.1590/S1806-37132011000500003

Osses, 2010, Prueba de caminata en seis minutos en sujetos chilenos sanos de 20 a 80 anos [Reference values for the 6-minutes walking test in healthy subjects 20–80 years old], Rev Med Chil, 138, 1124, 10.4067/S0034-98872010000900006

10.1016/j.rmed.2009.01.012

10.1016/j.rmed.2008.07.023

10.1590/S0100-879X2009005000032

10.3109/09593980802664711

Masmoudi, 2008, Le test de marche de six minutes: quelles valeurs predictives a appliquer pour les sujets ages entre 40 et 80 ans de la population Tunisienne? [The six minute walk test: which predictive values to apply for Tunisian subjects aged between 40 and 80 years?], Tunis Med, 86, 20

10.1016/j.rmed.2005.08.003

10.1016/j.rmed.2006.01.001

10.1111/j.1440-1843.2006.00820.x

10.1097/00008483-200103000-00005

10.1378/chest.123.2.387

Troosters, 1999, Six minute walking distance in healthy elderly subjects, Eur Respir J, 14, 270, 10.1034/j.1399-3003.1999.14b06.x

10.1164/ajrccm.158.5.9710086

10.1111/j.1440-1843.2006.00914.x

10.1590/S0066-782X2011005000024

Wise, 2005, Minimal clinically important differences in the six-minute walk test and the incremental shuttle walking test, COPD, 2, 125, 10.1081/COPD-200050527

10.1183/09031936.00140507

10.1183/09031936.00063810

10.1164/rccm.201209-1596OC

10.1136/thx.2009.113498

10.1378/chest.07-0275

10.1164/rccm.201203-0480OC

Lacasse, 2006, Pulmonary rehabilitation for chronic obstructive pulmonary disease, Cochrane Database Syst Rev, 4, CD003793

Puhan, 2009, Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease, Cochrane Database Syst Rev, 1, CD005305

Holland, 2008, Physical training for interstitial lung disease, Cochrane Database Syst Rev, 4, CD006322

Liu, 2009, Endothelin receptor antagonists for pulmonary arterial hypertension, Cochrane Database Syst Rev, 3, CD004434

10.1136/thx.47.12.1019

10.1186/1465-9921-7-127

10.1016/j.apmr.2006.03.005

10.1136/thorax.57.1.34

10.1177/1479972311415128

10.1097/PHM.0b013e3181fc7f42

10.1097/PHM.0b013e31824660bd

10.1007/s00421-003-0803-9

Palange, 2000, Ventilatory and metabolic adaptations to walking and cycling in patients with COPD, J Appl Physiol, 88, 1715, 10.1152/jappl.2000.88.5.1715

10.1016/j.ejcts.2004.07.036

10.1016/j.rmed.2009.01.009

10.1097/00008483-200501000-00010

10.1016/j.rmed.2011.11.002

10.1016/j.physio.2012.01.004

10.1016/j.rmed.2012.09.018

10.1097/HCR.0b013e3181e175f2

10.1016/j.rmed.2008.03.007

10.1016/j.rmed.2006.09.020

10.1016/j.rmed.2009.04.025

10.1097/HCR.0b013e3181e1736b

10.1016/j.rmed.2011.09.005

10.1016/j.ijcard.2007.01.037

10.1016/j.physio.2007.03.002

Pilat, 2005, Étude comparative du test de marche de six minutes, du test de la navette et de l’épreuve maximale sur cycloergomètre [Comparative study of the 6-minute walking test, the back-and-forth test, and the maximal test on an ergometric bicycle], Kinesither Rev, 5, 33

10.1159/000319037

10.1016/j.rmed.2011.07.023

10.1136/thoraxjnl-2011-201054b.119

10.1136/thx.2007.081208

10.1136/thx.2010.156372

10.1016/S1836-9553(10)70040-0

10.1177/1479972310378311

10.1191/1479972306cd077oa

10.1186/1465-9921-6-54

Puhan, 2011, Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease, Cochrane Database Syst Rev, 10, CD005305

10.1136/thx.54.3.213

Singh, 1994, Comparison of oxygen uptake during a conventional treadmill test and the shuttle walking test in chronic airflow limitation, Eur Respir J, 7, 2016, 10.1183/09031936.94.07112016

10.1016/j.rmed.2012.08.011

10.1016/j.physio.2009.02.001

10.1164/rccm.200506-925OC

10.1053/rmed.2000.0824

10.1177/1479972312438702