Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

iScience - Tập 26 - Trang 107823 - 2023
Darko Bosnakovski1,2, Erik A. Toso1,2, Elizabeth T. Ener1,2, Micah D. Gearhart3, Lulu Yin4, Felipe F. Lüttmann5, Alessandro Magli6, Ke Shi7, Johnny Kim8,9, Hideki Aihara7, Michael Kyba1,2
1Lillehei Heart Institute, University of Minnesota, Minneapolis, MN 55455, USA
2Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
3Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
4Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
5Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
6Department of Cardiology, University of Minnesota, Minneapolis, MN 55455, USA
7Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
8Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
9The Center for Cardiovascular Regeneration and Immunology at TRON – Translational Oncology, Johannes Gutenberg-University Mainz, Mainz, Germany

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