An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma

Journal of Allergy and Clinical Immunology - Tập 123 Số 4 - Trang 911-916 - 2009
Ingo Marenholz1,2, Tamara Kerscher1,2, Anja Bauerfeind1, Jorge Esparza-Gordillo1,2, Renate Nickel2, Thomas Keil3, Susanne Lau2, Klaus Rohde1, Ulrich Wahn2, Young‐Ae Lee1,2
1Max-Delbrück-Centrum (MDC) for Molecular Medicine, Berlin, Germany
2Pediatric Pneumology and Immunology, Charité, Berlin, Germany
3Institute for Social Medicine, Epidemiology and Health Economics, Charité, Berlin, Germany

Tóm tắt

Từ khóa


Tài liệu tham khảo

Asher, 2006, Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys, Lancet, 368, 733, 10.1016/S0140-6736(06)69283-0

Eder, 2006, The asthma epidemic, N Engl J Med, 355, 2226, 10.1056/NEJMra054308

Phelan, 2002, The Melbourne Asthma Study: 1964-1999, J Allergy Clin Immunol, 109, 189, 10.1067/mai.2002.120951

Sears, 2003, A longitudinal, population-based, cohort study of childhood asthma followed to adulthood, N Engl J Med, 349, 1414, 10.1056/NEJMoa022363

Morgan, 2005, Outcome of asthma and wheezing in the first 6 years of life: follow-up through adolescence, Am J Respir Crit Care Med, 172, 1253, 10.1164/rccm.200504-525OC

Vonk, 2004, Childhood factors associated with asthma remission after 30 year follow up, Thorax, 59, 925, 10.1136/thx.2003.016246

Grody, 2003, Molecular genetic risk screening, Annu Rev Med, 54, 473, 10.1146/annurev.med.54.101601.152127

Palmer, 2006, Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nat Genet, 38, 441, 10.1038/ng1767

Marenholz, 2006, Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march, J Allergy Clin Immunol, 118, 866, 10.1016/j.jaci.2006.07.026

Wahn, 2001, Childhood risk factors for atopy and the importance of early intervention, J Allergy Clin Immunol, 107, 567, 10.1067/mai.2001.112943

Guerra, 2008, Asthma genetics: from linear to multifactorial approaches, Annu Rev Med, 59, 327, 10.1146/annurev.med.59.060406.213232

Kulig, 1999, Serum IgE levels during the first 6 years of life, J Pediatr, 134, 453, 10.1016/S0022-3476(99)70203-9

Kulig, 1999, Natural course of sensitization to food and inhalant allergens during the first 6 years of life, J Allergy Clin Immunol, 103, 1173, 10.1016/S0091-6749(99)70195-8

Lowe, 2007, Skin prick test can identify eczematous infants at risk of asthma and allergic rhinitis, Clin Exp Allergy, 37, 1624, 10.1111/j.1365-2222.2007.02822.x

Lau, 2000, Early exposure to house-dust mite and cat allergens and development of childhood asthma: a cohort study. Multicentre Allergy Study Group, Lancet, 356, 1392, 10.1016/S0140-6736(00)02842-7

Bergmann, 1994, Atopic diseases in infancy. The German multicenter atopy study (MAS-90), Pediatr Allergy Immunol, 5, 19, 10.1111/j.1399-3038.1994.tb00343.x

Illi, 2004, The natural course of atopic dermatitis from birth to age 7 years and the association with asthma, J Allergy Clin Immunol, 113, 925, 10.1016/j.jaci.2004.01.778

Nickel, 2002, Comparison of bronchial responsiveness to histamine in asthma, allergic rhinitis and allergic sensitization at the age of 7 years, Clin Exp Allergy, 32, 1274, 10.1046/j.1365-2745.2002.01482.x

Sandilands, 2007, Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema, Nat Genet, 39, 650, 10.1038/ng2020

Cochran, 1954, Some methods for strengthening the common chi-squared tests, Biometrics, 10, 417, 10.2307/3001616

Bossuyt, 2003, The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration, Ann Intern Med, 138, W1, 10.7326/0003-4819-138-1-200301070-00012-w1

Rothman, 1998

Assmann, 1996, Confidence intervals for measures of interaction, Epidemiology, 7, 286, 10.1097/00001648-199605000-00012

Bergmann, 1998, Atopic dermatitis in early infancy predicts allergic airway disease at 5 years, Clin Exp Allergy, 28, 965, 10.1046/j.1365-2222.1998.00371.x

Halonen, 2006, Predicting the course of asthma, Allergy Asthma Proc, 27, 328, 10.2500/aap.2006.27.2888

Illi, 2006, Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study, Lancet, 368, 763, 10.1016/S0140-6736(06)69286-6

Thompson, 2004, The genetic epidemiology of breast cancer genes, J Mammary Gland Biol Neoplasia, 9, 221, 10.1023/B:JOMG.0000048770.90334.3b

2005, Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: recommendation statement, Ann Intern Med, 143, 355, 10.7326/0003-4819-143-5-200509060-00011

Lal, 2007, Attitudes toward genetic testing in patients with inflammatory bowel disease, Eur J Gastroenterol Hepatol, 19, 321, 10.1097/MEG.0b013e328013e9a8

Bieli, 2007, A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression, J Allergy Clin Immunol, 120, 1308, 10.1016/j.jaci.2007.07.034

Bottema, 2008, Interleukin 13, CD14, pet and tobacco smoke influence atopy in three Dutch cohorts: the allergenic study, Eur Respir J, 32, 593, 10.1183/09031936.00162407

Hunninghake, 2008, Dust mite exposure modifies the effect of functional IL10 polymorphisms on allergy and asthma exacerbations, J Allergy Clin Immunol, 122, 93, 10.1016/j.jaci.2008.03.015

Melen, 2008, Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease, Environ Health Perspect, 116, 1077, 10.1289/ehp.11117

Bisgaard, 2008, Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure, PLoS Med, 5, e131, 10.1371/journal.pmed.0050131

Stein, 2004, Asthma phenotypes in childhood: lessons from an epidemiological approach, Paediatr Respir Rev, 5, 155, 10.1016/j.prrv.2004.01.007

Danov, 2007, Prevention of asthma in childhood, Curr Opin Allergy Clin Immunol, 7, 174, 10.1097/ACI.0b013e32801d216a

Drazen, 1999, Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment, Nat Genet, 22, 168, 10.1038/9680