Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation
Tài liệu tham khảo
Altomare, 2005, Perturbations of the AKT signaling pathway in human cancer, Oncogene, 24, 7455, 10.1038/sj.onc.1209085
Bae, 2003, Isoform-specific regulation of insulin-dependent glucose uptake by Akt/PKB, J. Biol. Chem., 278, 49530, 10.1074/jbc.M306782200
Baggetto, 1992, Deviant energetic metabolism of glycolytic cancer cells, Biochimie, 74, 959, 10.1016/0300-9084(92)90016-8
Barber, 1997, Lipid metabolism in the lactating mammary gland, Biochim. Biophys. Acta, 1347, 101, 10.1016/S0005-2760(97)00079-9
Barnes, 2005, Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation, Oncogene, 24, 3257, 10.1038/sj.onc.1208461
Bauer, 2004, Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand, FASEB J., 18, 1303, 10.1096/fj.03-1001fje
Bauer, 2005, ATP citrate lyase is an important component of cell growth and transformation, Oncogene, 24, 6314, 10.1038/sj.onc.1208773
Berwick, 2002, The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes, J. Biol. Chem., 277, 33895, 10.1074/jbc.M204681200
Borst, 1982, Mouse mammary gland DNA synthesis during pregnancy, J. Exp. Zool., 221, 245, 10.1002/jez.1402210216
Buck, 2004, Biological characterisation of breast cancer by means of PET, Eur. J. Nucl. Med. Mol. Imaging, 31, S80, 10.1007/s00259-004-1529-6
Camps, 1994, High and polarized expression of GLUT1 glucose transporters in epithelial cells from mammary gland: acute down-regulation of GLUT1 carriers by weaning, Endocrinology, 134, 924, 10.1210/endo.134.2.8299587
Chen, 2004, Impaired platelet responses to thrombin and collagen in AKT-1-deficient mice, Blood, 104, 1703, 10.1182/blood-2003-10-3428
Chen, 2001, Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene, Genes Dev., 15, 2203, 10.1101/gad.913901
Cho, 2001, Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta), Science, 292, 1728, 10.1126/science.292.5522.1728
Cho, 2001, Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice, J. Biol. Chem., 276, 38349, 10.1074/jbc.C100462200
Chodosh, 2000, Protein kinase expression during murine mammary development, Dev. Biol., 219, 259, 10.1006/dbio.2000.9614
Dan, 2002, Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin, J. Biol. Chem., 277, 35364, 10.1074/jbc.M205838200
Detterbeck, 2004, Seeking a home for a PET, part 3: Emerging applications of positron emission tomography imaging in the management of patients with lung cancer, Chest, 126, 1656, 10.1378/chest.126.5.1656
Easton, 2005, Role for Akt3/protein kinase Bgamma in attainment of normal brain size, Mol. Cell. Biol., 25, 1869, 10.1128/MCB.25.5.1869-1878.2005
Fleischmann, 2000, Regulation of sterol regulatory-element binding protein 1 gene expression in liver: role of insulin and protein kinase B/cAkt, Biochem. J., 349, 13, 10.1042/0264-6021:3490013
Gagnon, 1999, Activation of protein kinase B and induction of adipogenesis by insulin in 3T3-L1 preadipocytes: contribution of phosphoinositide-3,4,5-trisphosphate versus phosphoinositide-3,4-bisphosphate, Diabetes, 48, 691, 10.2337/diabetes.48.4.691
Gardner, 2000, Developmental role of the SNF1-related kinase Hunk in pregnancy-induced changes in the mammary gland, Development, 127, 4493, 10.1242/dev.127.20.4493
Garofalo, 2003, Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta, J. Clin. Invest., 112, 197, 10.1172/JCI16885
Gottlob, 2001, Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase, Genes Dev., 15, 1406, 10.1101/gad.889901
Gunther, 2002, A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology, FASEB J., 16, 283, 10.1096/fj.01-0551com
Inoki, 2002, TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling, Nat. Cell Biol., 4, 648, 10.1038/ncb839
Jiang, 2003, Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing, Proc. Natl. Acad. Sci. USA, 100, 7569, 10.1073/pnas.1332633100
Kaplan, 1993, The mitochondrial tricarboxylate transport protein. cDNA cloning, primary structure, and comparison with other mitochondrial transport proteins, J. Biol. Chem., 268, 13682, 10.1016/S0021-9258(19)38701-0
Kohn, 1996, Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation, J. Biol. Chem., 271, 31372, 10.1074/jbc.271.49.31372
Kumar, 1994, Milk composition and lactation of beta-casein-deficient mice, Proc. Natl. Acad. Sci. USA, 91, 6138, 10.1073/pnas.91.13.6138
Listenberger, 2003, Triglyceride accumulation protects against fatty acid-induced lipotoxicity, Proc. Natl. Acad. Sci. USA, 100, 3077, 10.1073/pnas.0630588100
Magun, 1996, Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiation, Endocrinology, 137, 3590, 10.1210/endo.137.8.8754791
Manning, 2002, Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway, Mol. Cell, 10, 151, 10.1016/S1097-2765(02)00568-3
Master, 2002, Functional microarray analysis of mammary organogenesis reveals a developmental role in adaptive thermogenesis, Mol. Endocrinol., 16, 1185, 10.1210/mend.16.6.0865
Master, 2005, Genomic analysis of early murine mammary gland development using novel probe-level algorithms, Genome Biol., 6, R20, 10.1186/gb-2005-6-2-r20
Miyazaki, 2003, Role of stearoyl-coenzyme A desaturase in lipid metabolism, Prostaglandins Leukot. Essent. Fatty Acids, 68, 113, 10.1016/S0952-3278(02)00261-2
Miyazaki, 2005, Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development, Proc. Natl. Acad. Sci. USA, 102, 12501, 10.1073/pnas.0503132102
Ntambi, 2002, Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity, Proc. Natl. Acad. Sci. USA, 99, 11482, 10.1073/pnas.132384699
Plas, 2005, Akt-dependent transformation: there is more to growth than just surviving, Oncogene, 24, 7435, 10.1038/sj.onc.1209097
Plas, 2001, Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology, J. Biol. Chem., 276, 12041, 10.1074/jbc.M010551200
Porstmann, 2005, PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP, Oncogene, 24, 6465, 10.1038/sj.onc.1208802
Potter, 2002, Akt regulates growth by directly phosphorylating Tsc2, Nat. Cell Biol., 4, 658, 10.1038/ncb840
Rathmell, 2003, Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival, Mol. Cell. Biol., 23, 7315, 10.1128/MCB.23.20.7315-7328.2003
Rosen, 1999, Regulation of milk protein gene expression, Annu. Rev. Nutr., 19, 407, 10.1146/annurev.nutr.19.1.407
Schwertfeger, 2001, Mammary gland involution is delayed by activated Akt in transgenic mice, Mol. Endocrinol., 15, 867, 10.1210/mend.15.6.0663
Schwertfeger, 2003, Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation, J. Lipid Res., 44, 1100, 10.1194/jlr.M300045-JLR200
Shillingford, 2003, Proteotyping of mammary tissue from transgenic and gene knockout mice with immunohistochemical markers: a tool to define developmental lesions, J. Histochem. Cytochem., 51, 555, 10.1177/002215540305100501
Shimomura, 1997, Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells, J. Clin. Invest., 99, 838, 10.1172/JCI119247
Singh, 2004, Dietary fat regulates mammary stearoyl coA desaturase expression and activity in lactating mice, J. Dairy Res., 71, 1, 10.1017/S0022029903006502
Srere, 1959, The citrate cleavage enzyme. I. Distribution and purification, J. Biol. Chem., 234, 2544, 10.1016/S0021-9258(18)69735-2
Stinnakre, 1994, Creation and phenotypic analysis of alpha-lactalbumin-deficient mice, Proc. Natl. Acad. Sci. USA, 91, 6544, 10.1073/pnas.91.14.6544
Surti, 2005, Imaging performance of A-PET: a small animal PET camera, IEEE Trans. Med. Imaging, 24, 844, 10.1109/TMI.2005.844078
Tschopp, 2005, Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis, Development, 132, 2943, 10.1242/dev.01864
Van de Sande, 2002, Role of the phosphatidylinositol 3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cells, Cancer Res., 62, 642
Warburg, 1924, Uber den stoffwechsel der tumoren, Biochem. Z., 152, 319
Welsh, 2005, Role of protein kinase B in insulin-regulated glucose uptake, Biochem. Soc. Trans., 33, 346, 10.1042/BST0330346