Update on IgG4-mediated autoimmune diseases: New insights and new family members
Tài liệu tham khảo
Koneczny, 2018, A new classification system for IgG4 autoantibodies, Front Immunol, 9, 10.3389/fimmu.2018.00097
Huijbers, 2015, The expanding field of IgG4-mediated neurological autoimmune disorders, Eur J Neurol, 22, 1151, 10.1111/ene.12758
Kridin, 2017, Mortality and cause of death in patients with pemphigus, Acta Derm Venereol, 97, 607, 10.2340/00015555-2611
Niks, 2007, Epidemiology of myasthenia gravis with anti-muscle specific kinase antibodies in the Netherlands, J Neurol Neurosurg Psychiatry, 78, 417, 10.1136/jnnp.2006.102517
Carr, 2010, A systematic review of population based epidemiological studies in myasthenia gravis, BMC Neurol, 10, 46, 10.1186/1471-2377-10-46
Broers, 2019, Incidence and prevalence of chronic inflammatory demyelinating Polyradiculoneuropathy: a systematic review and meta-analysis, Neuroepidemiology, 52, 161, 10.1159/000494291
Cortese, 2020, Antibodies to neurofascin, contactin-1, and contactin-associated protein 1 in CIDP: Clinical relevance of IgG isotype, Neurol Neuroimmunol Neuroinflam, 7, 10.1212/NXI.0000000000000639
Hubner, 2016, Prevalence and age distribution of pemphigus and pemphigoid diseases in Germany, J Invest Dermatol, 136, 2495, 10.1016/j.jid.2016.07.013
Schmidt, 2019, Pemphigus, Lancet, 394, 882, 10.1016/S0140-6736(19)31778-7
Hu, 2017, GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia, J Clin Lipidol, 11, 964, 10.1016/j.jacl.2017.05.017
Beigneux, 2017, Autoantibodies against GPIHBP1 as a cause of hypertriglyceridemia, N Engl J Med, 376, 1647, 10.1056/NEJMoa1611930
Koneczny, 2019
Duan, 2019, Complement-independent bystander injury in AQP4-IgG seropositive neuromyelitis optica produced by antibody-dependent cellular cytotoxicity, Acta Neuropathol Commun, 7, 112, 10.1186/s40478-019-0766-7
Diny, 2017, Eosinophils in autoimmune diseases, Front Immunol, 8, 484, 10.3389/fimmu.2017.00484
Wener, 2011, Immune Complexes in Systemic Lupus Erythematosus, 321
Drachman, 1978, Myasthenic antibodies cross-link acetylcholine receptors to accelerate degradation, N Engl J Med, 298, 1116, 10.1056/NEJM197805182982004
Heinemann, 1977, Modulation of acetylcholine receptor by antibody against the receptor, Proc Natl Acad Sci U S A, 74, 3090, 10.1073/pnas.74.7.3090
Sabater, 2016, Cellular investigations with human antibodies associated with the anti-IgLON5 syndrome, J Neuroinflammation, 13, 226, 10.1186/s12974-016-0689-1
Carvajal-Gonzalez, 2014, Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes, Brain, 137, 2178, 10.1093/brain/awu142
Hughes, 2010, Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis, J Neurosci, 30, 5866, 10.1523/JNEUROSCI.0167-10.2010
Barcellini, 2015, New insights in the pathogenesis of autoimmune hemolytic Anemia, Transfusion Med Hemother, 42, 287, 10.1159/000439002
Ludwig, 2017, Mechanisms of autoantibody-induced pathology, Front Immunol, 8, 603, 10.3389/fimmu.2017.00603
Sadler, 2017, Pathophysiology of thrombotic thrombocytopenic purpura, Blood, 130, 1181, 10.1182/blood-2017-04-636431
Rapoport, 2007, The thyrotropin receptor in Graves’ disease, Thyroid, 17, 911, 10.1089/thy.2007.0170
Rapoport, 1998, The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies, Endocr Rev, 19, 673
Koneczny, 2013, MuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters, PLoS One, 8, 10.1371/journal.pone.0080695
Kasperkiewicz, 2017, Pemphigus, Nat Rev Dis Primers, 3, 17026, 10.1038/nrdp.2017.26
Lichtenstein, 1968, A quantitative in vitro study of the chromatographic distribution and immunoglobulin characteristics of human blocking antibody, J Immunol, 101, 317, 10.4049/jimmunol.101.2.317
Aalberse, 1983, Serologic aspects of IgG4 antibodies. I. Prolonged immunization results in an IgG4-restricted response, J Immunol, 130, 722, 10.4049/jimmunol.130.2.722
Nakagawa, 1985, The role of IgG4 as blocking antibodies in asthmatics and in bee keepers, Int Arch Allergy Appl Immunol, 77, 204, 10.1159/000233787
Platts-Mills, 2001, Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study, Lancet, 357, 752, 10.1016/S0140-6736(00)04168-4
Pinck, 1967, Disulphide bridges of a human immunoglobulin G protein, Nature, 216, 941, 10.1038/216941a0
Frangione, 1967, Disulphide bridges of immunoglobin G-1 heavy chains, Nature, 216, 939, 10.1038/216939b0
Frangione, 1969, Structural studies of immunoglobulin G, Nature, 221, 145, 10.1038/221145a0
Tian, 2015, In-depth analysis of subclass-specific conformational preferences of IgG antibodies, IUCrJ, 2, 9, 10.1107/S205225251402209X
Konig, 2017, Antibodies under pressure: a small-angle X-ray scattering study of immunoglobulin G under high hydrostatic pressure, Biophys Chem, 231, 45, 10.1016/j.bpc.2017.05.016
Schroeder, 2010, Structure and function of immunoglobulins, J Allergy Clin Immunol, 125, S41, 10.1016/j.jaci.2009.09.046
Lu, 2007, Solution conformation of wild-type and mutant IgG3 and IgG4 immunoglobulins using crystallohydrodynamics: possible implications for complement activation, Biophys J, 93, 3733, 10.1529/biophysj.107.108993
Abe, 2010, Masking of the fc region in human IgG4 by constrained X-ray scattering modelling: implications for antibody function and therapy, Biochem J, 432, 101, 10.1042/BJ20100641
Diebolder, 2014, Complement is activated by IgG hexamers assembled at the cell surface, Science, 343, 1260, 10.1126/science.1248943
Lhotta, 1999, Glomerular deposition of mannose-binding lectin in human glomerulonephritis, Nephrol Dial Transplant, 14, 881, 10.1093/ndt/14.4.881
Yang, 2016, IgG4 anti-phospholipase A2 receptor might activate lectin and alternative complement pathway meanwhile in idiopathic membranous nephropathy: an inspiration from a cross-sectional study, Immunol Res, 64, 919, 10.1007/s12026-016-8790-1
Segawa, 2010, IgG subclasses and complement pathway in segmental and global membranous nephropathy, Pediatr Nephrol, 25, 1091, 10.1007/s00467-009-1439-8
Ma, 2011, Membranous nephropathy-associated anti-phospholipase A2 receptor IgG4 autoantibodies activate the lectin complement pathway (abstract), J Am Soc Nephrol, 22, 62A
Hayashi, 2017, Glomerular mannose-binding lectin deposition in intrinsic antigen-related membranous nephropathy, Nephrol Dial Transplant, 33, 832, 10.1093/ndt/gfx235
Beck, 2014, Membranous nephropathy: from models to man, J Clin Invest, 124, 2307, 10.1172/JCI72270
Malhotra, 1995, Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein, Nat Med, 1, 237, 10.1038/nm0395-237
Roos, 2001, Human IgA activates the complement system via the mannan-binding lectin pathway, J Immunol, 167, 2861, 10.4049/jimmunol.167.5.2861
Tao, 1993, Structural features of human immunoglobulin G that determine isotype-specific differences in complement activation, J Exp Med, 178, 661, 10.1084/jem.178.2.661
Brekke, 1994, Human IgG isotype-specific amino acid residues affecting complement-mediated cell lysis and phagocytosis, Eur J Immunol, 24, 2542, 10.1002/eji.1830241042
Canfield, 1991, The binding affinity of human IgG for its high affinity fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region, J Exp Med, 173, 1483, 10.1084/jem.173.6.1483
Sondermann, 2000, The 3.2-a crystal structure of the human IgG1 fc fragment-fc gammaRIII complex, Nature, 406, 267, 10.1038/35018508
Shields, 2001, High resolution mapping of the binding site on human IgG1 for fc gamma RI, fc gamma RII, fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the fc gamma R, J Biol Chem, 276, 6591, 10.1074/jbc.M009483200
Radaev, 2001, The structure of a human type III Fcgamma receptor in complex with fc, J Biol Chem, 276, 16469, 10.1074/jbc.M100350200
Davies, 2013, Crystal structure of the human IgG4 C(H)3 dimer reveals the role of Arg409 in the mechanism of fab-arm exchange, Mol Immunol, 54, 1, 10.1016/j.molimm.2012.10.029
Labrijn, 2011, Species-specific determinants in the IgG CH3 domain enable fab-arm exchange by affecting the noncovalent CH3-CH3 interaction strength, J Immunol, 187, 3238, 10.4049/jimmunol.1003336
Blech, 2019, Structure of a therapeutic full-length anti-NPRA IgG4 antibody: dissecting conformational diversity, Biophys J, 116, 1637, 10.1016/j.bpj.2019.03.036
Schuurman, 2001, The inter-heavy chain disulfide bonds of IgG4 are in equilibrium with intra-chain disulfide bonds, Mol Immunol, 38, 1, 10.1016/S0161-5890(01)00050-5
Bloom, 1997, Intrachain disulfide bond in the core hinge region of human IgG4, Protein Sci, 6, 407, 10.1002/pro.5560060217
Angal, 1993, A single amino acid substitution abolishes the heterogeneity of chimeric mouse/human (IgG4) antibody, Mol Immunol, 30, 105, 10.1016/0161-5890(93)90432-B
King, 1992, Expression, purification and characterization of a mouse-human chimeric antibody and chimeric Fab’ fragment, Biochem J, 281, 317, 10.1042/bj2810317
Margni, 1988, Nonprecipitating asymmetric antibodies, Annu Rev Immunol, 6, 535, 10.1146/annurev.iy.06.040188.002535
van der Zee, 1986, Serologic aspects of IgG4 antibodies. II. IgG4 antibodies form small, nonprecipitating immune complexes due to functional monovalency, J Immunol, 137, 3566, 10.4049/jimmunol.137.11.3566
Petersen, 1974, An in vitro system for studying the kinetics of interchain disulfide bond formation in immunoglobulin G, J Biol Chem, 249, 5633, 10.1016/S0021-9258(20)79774-7
Colcher, 1989, Characterization and biodistribution of recombinant and recombinant/chimeric constructs of monoclonal antibody B72.3, Cancer Res, 49, 1738
van der Neut Kolfschoten, 2007, Anti-inflammatory activity of human IgG4 antibodies by dynamic fab arm exchange, Science, 317, 1554, 10.1126/science.1144603
Rispens, 2014, Dynamics of inter-heavy chain interactions in human immunoglobulin G (IgG) subclasses studied by kinetic fab arm exchange, J Biol Chem, 289, 6098, 10.1074/jbc.M113.541813
Young, 2014, Estimation of polyclonal IgG4 hybrids in normal human serum, Immunology, 142, 406, 10.1111/imm.12265
Koneczny, 2017, IgG4 autoantibodies against muscle-specific kinase undergo fab-arm exchange in myasthenia gravis patients, J Autoimmun, 77, 104, 10.1016/j.jaut.2016.11.005
Aalberse, 2009, Immunoglobulin G4: an odd antibody, Clin Exp Allergy, 39, 469, 10.1111/j.1365-2222.2009.03207.x
Collins, 2013, Enhanced cell-binding by allergen multimers: how complex is it?, Immunol Cell Biol, 91, 115, 10.1038/icb.2013.5
van der Zee, 1986, Inhibition of complement activation by IgG4 antibodies, Clin Exp Immunol, 64, 415
Davies, 2014, Structural determinants of unique properties of human IgG4-fc, J Mol Biol, 426, 630, 10.1016/j.jmb.2013.10.039
Rispens, 2009, Human IgG4 binds to IgG4 and conformationally altered IgG1 via fc-fc interactions, J Immunol, 182, 4275, 10.4049/jimmunol.0804338
Zack, 1995, Localization of an fc-binding reactivity to the constant region of human IgG4. Implications for the pathogenesis of rheumatoid arthritis, J Immunol, 155, 5057, 10.4049/jimmunol.155.10.5057
Kawa, 2008, A novel immunoglobulin-immunoglobulin interaction in autoimmunity, PLoS One, 3, 10.1371/journal.pone.0001637
Cohen, 1987, The subclass distribution of human IgG rheumatoid factor, J Immunol, 139, 1466, 10.4049/jimmunol.139.5.1466
Detlefsen, 2010, Deposition of complement C3c, immunoglobulin (Ig)G4 and IgG at the basement membrane of pancreatic ducts and acini in autoimmune pancreatitis, Histopathology, 57, 825, 10.1111/j.1365-2559.2010.03717.x
Ma, 2013, The role of complement in membranous nephropathy, Semin Nephrol, 33, 531, 10.1016/j.semnephrol.2013.08.004
Rees-Roberts, 2010, Inactivation of the complement anaphylatoxin C5a by secreted products of parasitic nematodes, Int J Parasitol, 40, 527, 10.1016/j.ijpara.2009.10.006
Maizels, 2003, Immune regulation by helminth parasites: cellular and molecular mechanisms, Nat Rev Immunol, 3, 733, 10.1038/nri1183
Babu, 2006, Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence, J Immunol, 176, 3248, 10.4049/jimmunol.176.5.3248
Adjobimey, 2010, Induction of immunoglobulin G4 in human filariasis: an indicator of immunoregulation, Ann Trop Med Parasitol, 104, 455, 10.1179/136485910X12786389891407
Prodjinotho, 2019, IgG4 antibodies from patients with asymptomatic bancroftian filariasis inhibit the binding of IgG1 and IgG2 to C1q in a fc-fc-dependent mechanism, Parasitol Res, 118, 2957, 10.1007/s00436-019-06451-2
Vidarsson, 2014, IgG subclasses and allotypes: from structure to effector functions, Front Immunol, 5, 520, 10.3389/fimmu.2014.00520
Nirula, 2011, What is IgG4? A review of the biology of a unique immunoglobulin subtype, Curr Opin Rheumatol, 23, 119, 10.1097/BOR.0b013e3283412fd4
Lighaam, 2016, The Immunobiology of immunoglobulin G4, Semin Liver Dis, 36, 200, 10.1055/s-0036-1584322
Van der Zee, 1987, IgG4 and hyposensitization, N Engl Reg Allergy Proc, 8, 389, 10.2500/108854187778999667
Margni, 1980, Immunobiological behaviour of rabbit precipitating and non-precipitating (co-precipitating) antibodies, Immunology, 41, 681
van Toorenenbergen, 1982, IgG4 and release of histamine from human peripheral blood leukocytes, Int Arch Allergy Appl Immunol, 67, 117, 10.1159/000233000
Aalberse, 1983, IgG4 as a blocking antibody, Clin Rev Allergy, 1, 289, 10.1007/BF02991163
James, 2012, Allergen specificity of IgG(4)-expressing B cells in patients with grass pollen allergy undergoing immunotherapy, J Allergy Clin Immunol, 130, 663, 10.1016/j.jaci.2012.04.006
Santos, 2015, IgG4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens, J Allergy Clin Immunol, 135, 1249, 10.1016/j.jaci.2015.01.012
Kemeny, 1983, Antibodies to purified bee venom proteins and peptides. II. A detailed study of changes in IgE and IgG antibodies to individual bee venom antigens, J Allergy Clin Immunol, 72, 376, 10.1016/0091-6749(83)90503-1
Kemeny, 1983, Changes in the levels of anti-phospholipase A2 and hyaluronidase antibodies during bee venom immunotherapy, Monogr Allergy, 18, 150
Resende, 2019, IgE, IgG1, and IgG4 reactivity to Dermatophagoides pteronyssinus glycosylated extract in allergic patients, Biomed Res Int, 2019, 9840890, 10.1155/2019/9840890
Subbarayal, 2013, Kinetics, cross-reactivity, and specificity of bet v 1-specific IgG4 antibodies induced by immunotherapy with birch pollen, Allergy, 68, 1377, 10.1111/all.12236
van Neerven, 1999, Blocking antibodies induced by specific allergy vaccination prevent the activation of CD4+ T cells by inhibiting serum-IgE-facilitated allergen presentation, J Immunol, 163, 2944, 10.4049/jimmunol.163.5.2944
Bodtger, 2005, Is immunotherapy-induced birch-pollen-specific IgG4 a marker for decreased allergen-specific sensitivity?, Int Arch Allergy Immunol, 136, 340, 10.1159/000084227
Crescioli, 2016, IgG4 characteristics and functions in Cancer immunity, Curr Allergy Asthma Rep, 16, 7, 10.1007/s11882-015-0580-7
Lopes, 2016, Helminth regulation of immunity: a three-pronged approach to treat colitis, Inflamm Bowel Dis, 22, 2499, 10.1097/MIB.0000000000000889
Maizels, 2019, Regulation of immunity and allergy by helminth parasites, Allergy, 75, 524, 10.1111/all.13944
Elliott, 2012, Helminth-host immunological interactions: prevention and control of immune-mediated diseases, Ann N Y Acad Sci, 1247, 83, 10.1111/j.1749-6632.2011.06292.x
Marple, 2017, Cutting edge: helminth coinfection blocks effector differentiation of CD8 T cells through alternate host Th2- and IL-10-mediated responses, J Immunol, 198, 634, 10.4049/jimmunol.1601741
Boctor, 1990, IgG subclasses in human chronic schistosomiasis: over-production of schistosome-specific and non-specific IgG4, Clin Exp Immunol, 82, 574, 10.1111/j.1365-2249.1990.tb05492.x
Satoguina, 2008, Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta, Eur J Immunol, 38, 3101, 10.1002/eji.200838193
Tang, 2019, Helminths protect against type 1 diabetes: effects and mechanisms, Parasitol Res, 118, 1087, 10.1007/s00436-019-06247-4
Shen, 2015, Suppressive functions of B cells in infectious diseases, Int Immunol, 27, 513, 10.1093/intimm/dxv037
Chapuy-Regaud, 2005, IgG subclass distribution of the rheumatoid arthritis-specific autoantibodies to citrullinated fibrin, Clin Exp Immunol, 139, 542, 10.1111/j.1365-2249.2004.02708.x
Panza, 2014, Immunoglobulin G subclass profile of anticitrullinated peptide antibodies specific for Epstein Barr virus-derived and histone-derived citrullinated peptides, J Rheumatol, 41, 407, 10.3899/jrheum.130795
Lundstrom, 2014, IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, fc-glycans and a fab-peptide sequence, PLoS One, 9, 10.1371/journal.pone.0113924
Engelmann, 2018, Decreased IgG4 ACPA levels in responders and increased CD1c(+) classical dendritic cells in non-responders of patients with rheumatoid arthritis under therapy, Clin Rheumatol, 37, 1783, 10.1007/s10067-018-4053-y
Bos, 2009, Preferential decrease in IgG4 anti-citrullinated protein antibodies during treatment with tumour necrosis factor blocking agents in patients with rheumatoid arthritis, Ann Rheum Dis, 68, 558, 10.1136/ard.2008.088401
Pan, 2017, Nature, functions, and clinical implications of IgG4 autoantibodies in systemic lupus erythematosus and rheumatoid arthritis, Discov Med, 23, 169
van de Stadt, 2014, Antibodies to IgG4 hinge can be found in rheumatoid arthritis patients during all stages of disease and may exacerbate chronic antibody-mediated inflammation, Arthritis Rheum, 66, 1133, 10.1002/art.38335
Falkenburg, 2017, Anti-hinge antibodies recognize IgG subclass- and protease-restricted Neoepitopes, J Immunol, 198, 82, 10.4049/jimmunol.1601096
Umehara, 2019, The front line of research into immunoglobin G4-related disease - do autoantibodies cause immunoglobin G4-related disease?, Mod Rheumatol, 29, 214, 10.1080/14397595.2018.1558519
Watanabe, 2018, Mechanistic insights into autoimmune pancreatitis and IgG4-related disease, Trends Immunol, 39, 874, 10.1016/j.it.2018.09.005
Pagliari, 2019, Autoimmune pancreatitis in children: the impact of immune system in a challenging disease, Autoimmun Rev, 18, 209, 10.1016/j.autrev.2018.09.006
Akiyama, 2019, Characteristics and prognosis of IgG4-related periaortitis/periarteritis: a systematic literature review, Autoimmun Rev, 18, 102354, 10.1016/j.autrev.2019.102354
Morales, 2019, An update on IgG4-related lung disease, Eur J Intern Med, 66, 18, 10.1016/j.ejim.2019.06.010
Romano, 2019, Autoimmune phenomena involving the pituitary gland in children: new developing data about diagnosis and treatment, Autoimmun Rev, 18, 102363, 10.1016/j.autrev.2019.102363
Stone, 2012, IgG4-related disease: nomenclature, clinical features, and treatment, Semin Diagn Pathol, 29, 177, 10.1053/j.semdp.2012.08.002
Umehara, 2017, How to diagnose IgG4-related disease, Ann Rheum Dis, 76, 10.1136/annrheumdis-2017-211330
Bozzalla Cassione, 2017, IgG4-related disease, Curr Opin Rheumatol, 29, 223, 10.1097/BOR.0000000000000383
Shiokawa, 2016, Pathogenicity of IgG in patients with IgG4-related disease, Gut, 65, 1322, 10.1136/gutjnl-2015-310336
Hubers, 2018, Annexin A11 is targeted by IgG4 and IgG1 autoantibodies in IgG4-related disease, Gut, 67, 728
Perugino, 2019, Identification of galectin-3 as an autoantigen in patients with IgG4-related disease, J Allergy Clin Immunol, 143, 736, 10.1016/j.jaci.2018.05.011
Yamada, 2018, LatY136F knock-in mouse model for human IgG4-related disease, PLoS One, 13, 10.1371/journal.pone.0198417
Witebsky, 1957, Chronic thyroiditis and autoimmunization, JAMA, 164, 1439, 10.1001/jama.1957.02980130015004
Rose, 1993, Defining criteria for autoimmune diseases(Witebsky’s postulates revisited), Immunol Today, 14, 426, 10.1016/0167-5699(93)90244-F
Naparstek, 1993, The role of autoantibodies in autoimmune disease, Annu Rev Immunol, 11, 79, 10.1146/annurev.iy.11.040193.000455
Hoch, 2001, Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies, Nat Med, 7, 365, 10.1038/85520
McConville, 2004, Detection and characterization of MuSK antibodies in seronegative myasthenia gravis, Ann Neurol, 55, 580, 10.1002/ana.20061
Huijbers, 2016, Longitudinal epitope mapping in MuSK myasthenia gravis: implications for disease severity, J Neuroimmunol, 291, 82, 10.1016/j.jneuroim.2015.12.016
Takamori, 2013, Antibodies against Wnt receptor of muscle-specific tyrosine kinase in myasthenia gravis, J Neuroimmunol, 254, 183, 10.1016/j.jneuroim.2012.09.001
Otsuka, 2015, Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling, Sci Rep, 5, 13928, 10.1038/srep13928
Zhang, 2011, Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK), J Biol Chem, 286, 40624, 10.1074/jbc.M111.279307
Huijbers, 2013, MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4, Proc Natl Acad Sci U S A, 110, 20783, 10.1073/pnas.1313944110
Koneczny, 2014, Potential mechanisms in MuSK myasthenia gravis
Huijbers, 2019, MuSK myasthenia gravis monoclonal antibodies: Valency dictates pathogenicity, Neurol Neuroimmunol Neuroinflam, 6, e547, 10.1212/NXI.0000000000000547
Mori, 2012, Antibodies against muscle-specific kinase impair both presynaptic and postsynaptic functions in a murine model of myasthenia gravis, Am J Pathol, 180, 798, 10.1016/j.ajpath.2011.10.031
Morsch, 2012, Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors, Exp Neurol, 237, 286, 10.1016/j.expneurol.2012.06.034
Selcen, 2004, Are MuSK antibodies the primary cause of myasthenic symptoms?, Neurology, 62, 1945, 10.1212/01.WNL.0000128048.23930.1D
Viegas, 2012, Passive and active immunization models of MuSK-ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects, Exp Neurol, 234, 506, 10.1016/j.expneurol.2012.01.025
Niks, 2010, Pre- and postsynaptic neuromuscular junction abnormalities in musk myasthenia, Muscle Nerve, 42, 283, 10.1002/mus.21642
Yumoto, 2012, Lrp4 is a retrograde signal for presynaptic differentiation at neuromuscular synapses, Nature, 489, 438, 10.1038/nature11348
Wu, 2012, Distinct roles of muscle and motoneuron LRP4 in neuromuscular junction formation, Neuron, 75, 94, 10.1016/j.neuron.2012.04.033
Sabre, 2019, Cognitive dysfunction in mice with passively induced MuSK antibody seropositive myasthenia gravis, J Neurol Sci, 399, 15, 10.1016/j.jns.2019.02.001
Faivre-Sarrailh, 2013, Neuro-glial interactions at the nodes of Ranvier: implication in health and diseases, Front Cell Neurosci, 7, 196, 10.3389/fncel.2013.00196
Peles, 1997, Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions, EMBO J, 16, 978, 10.1093/emboj/16.5.978
Rios, 2000, Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination, J Neurosci, 20, 8354, 10.1523/JNEUROSCI.20-22-08354.2000
Charles, 2002, Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction, Curr Biol, 12, 217, 10.1016/S0960-9822(01)00680-7
Doppler, 2016, Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy, Brain, 139, 2617, 10.1093/brain/aww189
Querol, 2012, Antibodies to contactin-1 in chronic inflammatory demyelinating polyneuropathy, Ann Neurol, 3, 370
Miura, 2015, Contactin 1 IgG4 associates to chronic inflammatory demyelinating polyneuropathy with sensory ataxia, Brain, 138, 1484, 10.1093/brain/awv054
Doppler, 2015, Destruction of paranodal architecture in inflammatory neuropathy with anti-contactin-1 autoantibodies, J Neurol Neurosurg Psychiatry, 86, 720, 10.1136/jnnp-2014-309916
Labasque, 2014, Specific contactin N-glycans are implicated in neurofascin binding and autoimmune targeting in peripheral neuropathies, J Biol Chem, 289, 7907, 10.1074/jbc.M113.528489
Sistani, 2013, Neuronal proteins are novel components of podocyte major processes and their expression in glomerular crescents supports their role in crescent formation, Kidney Int, 83, 63, 10.1038/ki.2012.321
Reid, 1994, Identification and characterization of the human cell adhesion molecule contactin, Brain Res Mol Brain Res, 21, 1, 10.1016/0169-328X(94)90372-7
Taieb, 2019, “neuro-renal syndrome” related to anti-contactin-1 antibodies, Muscle Nerve, 59, E19, 10.1002/mus.26392
Doppler, 2019, Anti-CNTN1 IgG3 induces acute conduction block and motor deficits in a passive transfer rat model, J Neuroinflammation, 16, 73, 10.1186/s12974-019-1462-z
Kanigicherla, 2013, Anti-PLA2R antibodies measured by ELISA predict long-term outcome in a prevalent population of patients with idiopathic membranous nephropathy, Kidney Int, 83, 940, 10.1038/ki.2012.486
Manso, 2016, Contactin-1 IgG4 antibodies cause paranode dismantling and conduction defects, Brain, 139, 1700, 10.1093/brain/aww062
Bhat, 2001, Axon-glia interactions and the domain organization of myelinated axons requires neurexin IV/Caspr/Paranodin, Neuron, 30, 369, 10.1016/S0896-6273(01)00294-X
Boyle, 2001, Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve, Neuron, 30, 385, 10.1016/S0896-6273(01)00296-3
Sherman, 2005, Neurofascins are required to establish axonal domains for saltatory conduction, Neuron, 48, 737, 10.1016/j.neuron.2005.10.019
Ng, 2012, Neurofascin as a target for autoantibodies in peripheral neuropathies, Neurology, 79, 2241, 10.1212/WNL.0b013e31827689ad
Devaux, 2016, Neurofascin-155 IgG4 in chronic inflammatory demyelinating polyneuropathy, Neurology, 86, 800, 10.1212/WNL.0000000000002418
Kadoya, 2016, IgG4 anti-neurofascin155 antibodies in chronic inflammatory demyelinating polyradiculoneuropathy: clinical significance and diagnostic utility of a conventional assay, J Neuroimmunol, 301, 16, 10.1016/j.jneuroim.2016.10.013
Painous, 2018, Head and voice tremor improving with immunotherapy in an anti-NF155 positive CIDP patient, Ann Clin Transl Neurol, 5, 499, 10.1002/acn3.539
Querol, 2015, Rituximab in treatment-resistant CIDP with antibodies against paranodal proteins, Neurol Neuroimmunol Neuroinflamm, 2, 10.1212/NXI.0000000000000149
Bailly, 2018, Tremor associated with chronic inflammatory demyelinating polyneuropathy and anti-Neurofascin-155 antibodies, Tremor Other Hyperkinet Mov, 8, 606, 10.5334/tohm.451
Briani, 2019, Tongue tremor in neurofascin-155 IgG4 seropositive chronic inflammatory polyradiculoneuropathy, J Neuroimmunol, 330, 178, 10.1016/j.jneuroim.2019.01.017
Manso, 2019, Anti-Neurofascin-155 IgG4 antibodies prevent paranodal complex formation in vivo, J Clin Invest, 130
Dutta, 2018, Regulation of myelin structure and conduction velocity by perinodal astrocytes, Proc Natl Acad Sci U S A, 115, 11832, 10.1073/pnas.1811013115
Thomas, 2015, Pathogenicity of anti-ADAMTS13 autoantibodies in acquired thrombotic thrombocytopenic Purpura, Ebiomedicine, 2, 942, 10.1016/j.ebiom.2015.06.007
Tsai, 1998, Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura, N Engl J Med, 339, 1585, 10.1056/NEJM199811263392203
Schaller, 2014, The splenic autoimmune response to ADAMTS13 in thrombotic thrombocytopenic purpura contains recurrent antigen-binding CDR3 motifs, Blood, 124, 3469, 10.1182/blood-2014-04-561142
Sinkovits, 2018, Concentration and subclass distribution of anti-ADAMTS13 IgG autoantibodies in different stages of acquired idiopathic thrombotic thrombocytopenic Purpura, Front Immunol, 9, 1646, 10.3389/fimmu.2018.01646
Kremer Hovinga, 2017, Thrombotic thrombocytopenic purpura, Nat Rev Dis Primers, 3, 17020, 10.1038/nrdp.2017.20
Ostertag, 2016, ADAMTS13 autoantibodies cloned from patients with acquired thrombotic thrombocytopenic purpura: 2. Pathogenicity in an animal model, Transfusion, 56, 1775, 10.1111/trf.13583
Stanley, 2006, Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome, N Engl J Med, 355, 1800, 10.1056/NEJMra061111
Amagai, 2003, Desmoglein as a target in autoimmunity and infection, J Am Acad Dermatol, 48, 244, 10.1067/mjd.2003.7
Di Zenzo, 2012, Pemphigus autoantibodies generated through somatic mutations target the desmoglein-3 cis-interface, J Clin Invest, 122, 3781, 10.1172/JCI64413
Li, 2003, The role of intramolecular epitope spreading in the pathogenesis of endemic pemphigus foliaceus (fogo selvagem), J Exp Med, 197, 1501, 10.1084/jem.20022031
Futei, 2001, Predominant IgG4 subclass in autoantibodies of pemphigus vulgaris and foliaceus, J Dermatol Sci, 26, 55, 10.1016/S0923-1811(00)00158-4
Rock, 1989, The pathogenic effect of IgG4 autoantibodies in endemic pemphigus foliaceus (fogo selvagem), N Engl J Med, 320, 1463, 10.1056/NEJM198906013202206
Payne, 2005, Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display, J Clin Invest, 115, 888, 10.1172/JCI24185
Ishii, 2005, In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of anti-desmoglein 3 IgG autoantibodies in pemphigus vulgaris, J Invest Dermatol, 124, 939, 10.1111/j.0022-202X.2005.23714.x
Saito, 2012, Signaling dependent and independent mechanisms in pemphigus vulgaris blister formation, PLoS One, 7, 10.1371/journal.pone.0050696
Evangelista, 2018, Pathogenic IgG4 autoantibodies from endemic pemphigus foliaceus recognize a desmoglein-1 conformational epitope, J Autoimmun, 89, 171, 10.1016/j.jaut.2017.12.017
Waschke, 2006, Inhibition of rho a activity causes pemphigus skin blistering, J Cell Biol, 175, 721, 10.1083/jcb.200605125
Li, 2009, Involvement of the apoptotic mechanism in pemphigus foliaceus autoimmune injury of the skin, J Immunol, 182, 711, 10.4049/jimmunol.182.1.711
Cipolla, 2017, Crosstalk between signaling pathways in pemphigus: a role for endoplasmic reticulum stress in p38 mitogen-activated protein kinase activation?, Front Immunol, 8, 1022, 10.3389/fimmu.2017.01022
Egu, 2017, Inhibition of p38MAPK signaling prevents epidermal blistering and alterations of desmosome structure induced by pemphigus autoantibodies in human epidermis, Br J Dermatol, 6, 1612, 10.1111/bjd.15721
Mavropoulos, 2013, p38 MAPK signaling in pemphigus: implications for skin autoimmunity, Autoimmune Dis, 2013, 728529
Spindler, 2010, Protective endogenous cyclic adenosine 5′-monophosphate signaling triggered by pemphigus autoantibodies, J Immunol, 185, 6831, 10.4049/jimmunol.1002675
Walter, 2017, Different signaling patterns contribute to loss of keratinocyte cohesion dependent on autoantibody profile in pemphigus, Sci Rep, 7, 3579, 10.1038/s41598-017-03697-7
Funakoshi, 2012, Enrichment of total serum IgG4 in patients with pemphigus, Br J Dermatol, 167, 1245, 10.1111/j.1365-2133.2012.11144.x
Zhao, 2016, Neonatal autoimmune blistering disease: a systematic review, Pediatr Dermatol, 33, 367, 10.1111/pde.12859
Tsunoda, 2003, Induction of pemphigus phenotype by a mouse monoclonal antibody against the amino-terminal adhesive interface of desmoglein 3, J Immunol, 170, 2170, 10.4049/jimmunol.170.4.2170
Irani, 2011, Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis, Ann Neurol, 69, 892, 10.1002/ana.22307
Irani, 2010, Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia, Brain, 133, 2734, 10.1093/brain/awq213
Arino, 2016, Anti-LGI1-associated cognitive impairment: presentation and long-term outcome, Neurology, 87, 759, 10.1212/WNL.0000000000003009
van Sonderen, 2016, Anti-LGI1 encephalitis: clinical syndrome and long-term follow-up, Neurology, 87, 1449, 10.1212/WNL.0000000000003173
Bastiaansen, 2017, Autoimmune encephalitis with anti-leucine-rich glioma-inactivated 1 or anti-contactin-associated protein-like 2 antibodies (formerly called voltage-gated potassium channel-complex antibodies), Curr Opin Neurol, 30, 302, 10.1097/WCO.0000000000000444
Fukata, 2006, Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission, Science, 313, 1792, 10.1126/science.1129947
Yamagata, 2018, Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22, Nat Commun, 9, 1546, 10.1038/s41467-018-03947-w
Lovero, 2015, The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function, Proc Natl Acad Sci U S A, 112, E4129, 10.1073/pnas.1511910112
Miller, 2017, Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis, Brain, 140, 1212, 10.1093/brain/awx070
Aysit-Altuncu, 2018, Effect of LGI1 antibody-positive IgG on hippocampal neuron survival: a preliminary study, Neuroreport, 29, 932, 10.1097/WNR.0000000000001055
Ohkawa, 2013, Autoantibodies to epilepsy-related LGI1 in limbic encephalitis neutralize LGI1-ADAM22 interaction and reduce synaptic AMPA receptors, J Neurosci, 33, 18161, 10.1523/JNEUROSCI.3506-13.2013
Thompson, 2018, The importance of early immunotherapy in patients with faciobrachial dystonic seizures, Brain, 141, 348, 10.1093/brain/awx323
Seagar, 2017, LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels, Proc Natl Acad Sci U S A, 114, 7719, 10.1073/pnas.1618656114
Lancaster, 2019, ADAM23 is a negative regulator of Kv1.1/Kv1.4 potassium currents, Neurosci Lett, 704, 159, 10.1016/j.neulet.2019.04.012
Petit-Pedrol, 2018, LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory, Brain, 141, 3144
Lalic, 2011, Human limbic encephalitis serum enhances hippocampal mossy fiber-CA3 pyramidal cell synaptic transmission, Epilepsia, 52, 121, 10.1111/j.1528-1167.2010.02756.x
Yu, 2010, Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability, Hum Mol Genet, 19, 1702, 10.1093/hmg/ddq047
Lancaster, 2011, Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia, Ann Neurol, 69, 303, 10.1002/ana.22297
Vincent, 2010, Caspr2 antibodies in patients with thymomas, J Thorac Oncol, 5, S277, 10.1097/JTO.0b013e3181f23f04
Vale, 2017, Morvan syndrome as a paraneoplastic disorder of thymoma with anti-CASPR2 antibodies, Lancet, 389, 1367, 10.1016/S0140-6736(16)31459-3
van Sonderen, 2017, The value of LGI1, Caspr2 and voltage-gated potassium channel antibodies in encephalitis, Nat Rev Neurol, 13, 290, 10.1038/nrneurol.2017.43
van Sonderen, 2016, The clinical spectrum of Caspr2 antibody-associated disease, Neurology, 87, 521, 10.1212/WNL.0000000000002917
Joubert, 2016, Characterization of a subtype of autoimmune encephalitis with anti-Contactin-associated protein-like 2 antibodies in the cerebrospinal fluid, prominent limbic symptoms, and seizures, JAMA Neurol., 73, 1115, 10.1001/jamaneurol.2016.1585
Sunwoo, 2015, Clinical manifestations of patients with CASPR2 antibodies, J Neuroimmunol, 281, 17, 10.1016/j.jneuroim.2015.03.005
Klein, 2013, Insights from LGI1 and CASPR2 potassium channel complex autoantibody subtyping, JAMA Neurol, 70, 229, 10.1001/jamaneurol.2013.592
Bien, 2017, Anti-contactin-associated protein-2 encephalitis: relevance of antibody titres, presentation and outcome, Eur J Neurol, 24, 175, 10.1111/ene.13180
Somers, 2011, Psychiatric manifestations of voltage-gated potassium-channel complex autoimmunity, J Neuropsychiatry Clin Neurosci, 23, 425, 10.1176/jnp.23.4.jnp425
Poliak, 1999, Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels, Neuron, 24, 1037, 10.1016/S0896-6273(00)81049-1
Scott, 2019, Loss of Cntnap2 causes axonal excitability deficits, developmental delay in cortical myelination, and abnormal stereotyped motor behavior, Cerebral Cortex, 29, 586, 10.1093/cercor/bhx341
Dawes, 2018, Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability, Neuron, 97, 806, 10.1016/j.neuron.2018.01.033
Patterson, 2018, Mechanisms of Caspr2 antibodies in autoimmune encephalitis and neuromyotonia, Ann Neurol, 83, 40, 10.1002/ana.25120
Pinatel, 2015, Inhibitory axons are targeted in hippocampal cell culture by anti-Caspr2 autoantibodies associated with limbic encephalitis, Front Cell Neurosci, 9, 265, 10.3389/fncel.2015.00265
Saint-Martin, 2019, Impact of anti-CASPR2 autoantibodies from patients with autoimmune encephalitis on CASPR2/TAG-1 interaction and Kv1 expression, J Autoimmun, 103, 102284, 10.1016/j.jaut.2019.05.012
Fernandes, 2019, Disrupted AMPA receptor function upon genetic- or antibody-mediated loss of autism-associated CASPR2, Cereb Cortex, 12, 4919, 10.1093/cercor/bhz032
Giannoccaro, 2019, Behaviour and neuropathology in mice injected with human contactin-associated protein 2 antibodies, Brain, 142, 2000, 10.1093/brain/awz119
Becker, 2012, Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia, J Neurol Neurosurg Psychiatry, 83, 437, 10.1136/jnnp-2011-301506
Davies, 2010, GPIHBP1 is responsible for the entry of lipoprotein lipase into capillaries, Cell Metab, 12, 42, 10.1016/j.cmet.2010.04.016
Mysling, 2016, The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain, eLife, 5
Mysling, 2016, The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding, eLife, 5
Eguchi, 2019, GPIHBP1 autoantibody syndrome during interferon beta1a treatment, J Clin Lipidol, 13, 62, 10.1016/j.jacl.2018.10.004
Keri, 2019, Primary membranous nephropathy: comprehensive review and historical perspective, Postgrad Med J, 95, 23, 10.1136/postgradmedj-2018-135729
Cattran, 2017, Membranous nephropathy: integrating basic science into improved clinical management, Kidney Int, 91, 566, 10.1016/j.kint.2016.09.048
Doi, 1984, Distribution of IgG subclasses in membranous nephropathy, Clin Exp Immunol, 58, 57
De Vriese, 2017, A proposal for a serology-based approach to membranous nephropathy, J Am Soc Nephrol, 28, 421, 10.1681/ASN.2016070776
Beck, 2009, M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy, N Engl J Med, 361, 11, 10.1056/NEJMoa0810457
Cheng, 2019, Serum phospholipase A2 receptor antibodies and immunoglobulin G subtypes in adult idiopathic membranous nephropathy: clinical value assessment, Clin Chim Acta, 490, 135, 10.1016/j.cca.2018.12.027
Murtas, 2012, Coexistence of different circulating anti-podocyte antibodies in membranous nephropathy, Clin J Am Soc Nephrol, 7, 1394, 10.2215/CJN.02170312
Zhang, 2019, A comparison of clinical features between idiopathic membranous nephropathy patients with and without serum antibody against phospholipase A2 receptor, Medicine (Baltimore), 98
Hofstra, 2012, Antiphospholipase A2 receptor antibody titer and subclass in idiopathic membranous nephropathy, J Am Soc Nephrol, 23, 1735, 10.1681/ASN.2012030242
Garcia-Vives, 2019, Antibodies to M-type phospholipase A2 receptor (PLA2R) in membranous lupus nephritis, Lupus, 28, 396, 10.1177/0961203319828521
Al-Rabadi, 2018, Concurrent presentation of thrombotic thrombocytopenic Purpura and membranous nephropathy, Kidney Int Rep, 3, 476, 10.1016/j.ekir.2017.08.005
Huang, 2013, IgG subclass staining in renal biopsies with membranous glomerulonephritis indicates subclass switch during disease progression, Mod Pathol, 26, 799, 10.1038/modpathol.2012.237
Salant, 2019, Unmet challenges in membranous nephropathy, Curr Opin Nephrol Hypertens, 28, 70, 10.1097/MNH.0000000000000459
Lambeau, 1999, Receptors for a growing family of secreted phospholipases A2, Trends Pharmacol Sci, 20, 162, 10.1016/S0165-6147(99)01300-0
Sukocheva, 2019, Current insights into functions of phospholipase A2 receptor in normal and cancer cells: more questions than answers, Semin Cancer Biol, 56, 116, 10.1016/j.semcancer.2017.11.002
Fresquet, 2017, PLA2R binds to the annexin A2-S100A10 complex in human podocytes, Sci Rep, 7, 6876, 10.1038/s41598-017-07028-8
Bharadwaj, 2013, Annexin A2 heterotetramer: structure and function, Int J Mol Sci, 14, 6259, 10.3390/ijms14036259
Fresquet, 2015, Identification of a major epitope recognized by PLA2R autoantibodies in primary membranous nephropathy, J Am Soc Nephrol, 26, 302, 10.1681/ASN.2014050502
Kao, 2015, Identification of the immunodominant epitope region in phospholipase A2 receptor-mediating autoantibody binding in idiopathic membranous nephropathy, J Am Soc Nephrol, 26, 291, 10.1681/ASN.2013121315
Skoberne, 2014, Serum with phospholipase A2 receptor autoantibodies interferes with podocyte adhesion to collagen, Eur J Clin Invest, 44, 753, 10.1111/eci.12292
Jurgensen, 2014, Complex determinants in specific members of the mannose receptor family govern collagen endocytosis, J Biol Chem, 289, 7935, 10.1074/jbc.M113.512780
Beck, 2017, PLA2R and THSD7A: disparate paths to the same disease?, J Am Soc Nephrol, 28, 2579, 10.1681/ASN.2017020178
Chi, 2019, The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy, J Formos Med Assoc, 118, 898, 10.1016/j.jfma.2018.12.026
Zhang, 2018, Clinical and prognostic significance of glomerular C1q deposits in primary MN, Clin Chim Acta, 485, 152, 10.1016/j.cca.2018.06.050
Hayashi, 2015, Clinicopathological characteristics of M-type phospholipase A2 receptor (PLA2R)-related membranous nephropathy in Japanese, Clin Exp Nephrol, 19, 797, 10.1007/s10157-014-1064-0
Debiec, 2012, Recurrent membranous nephropathy in an allograft caused by IgG3kappa targeting the PLA2 receptor, J Am Soc Nephrol, 23, 1949, 10.1681/ASN.2012060577
Haddad, 2017, An in vitro model of idiopathic membranous nephropathy reveals PLA2R- and complement-dependent pathways of podocyte injury, J Am Soc Nephrol, 20, 109A
Hayashi, 2018, Glomerular mannose-binding lectin deposition in intrinsic antigen-related membranous nephropathy, Nephrol Dial Transplant, 33, 832, 10.1093/ndt/gfx235
Bally, 2016, Phospholipase A2 receptor-related membranous nephropathy and Mannan-binding lectin deficiency, J Am Soc Nephrol, 27, 3539, 10.1681/ASN.2015101155
Michalski, 2015, Primary Ficolin-3 deficiency--is it associated with increased susceptibility to infections?, Immunobiology, 220, 711, 10.1016/j.imbio.2015.01.003
Dekkers, 2018, Novel concepts of altered immunoglobulin G Galactosylation in autoimmune diseases, Front Immunol, 9, 553, 10.3389/fimmu.2018.00553
Foster, 2016, Optimizing the translational value of animal models of glomerulonephritis: insights from recent murine prototypes, Am J Physiol Renal Physiol, 311, F487, 10.1152/ajprenal.00275.2016
Luo, 2018, Alternative pathway is essential for glomerular complement activation and proteinuria in a mouse model of membranous nephropathy, Front Immunol, 9, 1433, 10.3389/fimmu.2018.01433
Hoxha, 2017, An indirect immunofluorescence method facilitates detection of thrombospondin type 1 domain-containing 7A-specific antibodies in membranous nephropathy, J Am Soc Nephrol, 28, 520, 10.1681/ASN.2016010050
Stoddard, 2019, Structure and function insights garnered from in silico modeling of the thrombospondin type-1 domain-containing 7A antigen, Proteins, 87, 136, 10.1002/prot.25640
Seifert, 2018, The most N-terminal region of THSD7A is the predominant target for autoimmunity in THSD7A-associated membranous nephropathy, J Am Soc Nephrol, 29, 1536, 10.1681/ASN.2017070805
Herwig, 2019, Thrombospondin type 1 domain-containing 7A localizes to the slit diaphragm and stabilizes membrane dynamics of fully differentiated podocytes, J Am Soc Nephrol, 30, 824, 10.1681/ASN.2018090941
Iwakura, 2015, Prevalence of enhanced granular expression of thrombospondin Type-1 domain-containing 7A in the glomeruli of Japanese patients with idiopathic membranous nephropathy, PLoS One, 10, 10.1371/journal.pone.0138841
Tomas, 2014, Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy, N Engl J Med, 371, 2277, 10.1056/NEJMoa1409354
Kronbichler, 2017, Recent Progress in deciphering the Etiopathogenesis of primary membranous nephropathy, Biomed Res Int, 2017, 1936372, 10.1155/2017/1936372
Wang, 2017, Circulating antibodies against thrombospondin type-I domain-containing 7A in Chinese patients with idiopathic membranous nephropathy, Clin J Am Soc Nephrol, 12, 1642, 10.2215/CJN.01460217
Hoxha, 2016, A mechanism for Cancer-associated membranous nephropathy, N Engl J Med, 374, 1995, 10.1056/NEJMc1511702
Tomas, 2016, Autoantibodies against thrombospondin type 1 domain-containing 7A induce membranous nephropathy, J Clin Invest, 126, 2519, 10.1172/JCI85265
Tomas, 2017, A heterologous model of thrombospondin type 1 domain-containing 7A-associated membranous nephropathy, J Am Soc Nephrol, 11, 3262, 10.1681/ASN.2017010030
Wang, 2018, Human anti-thrombospondin type 1 domain-containing 7A antibodies induce membranous nephropathy through activation of lectin complement pathway, Biosci Rep, 38
Goletz, 2019, A sensitive and specific assay for the serological diagnosis of antilaminin 332 mucous membrane pemphigoid, Br J Dermatol, 180, 149, 10.1111/bjd.17202
Verrando, 1991, Monoclonal antibody GB3 defines a widespread defect of several basement membranes and a keratinocyte dysfunction in patients with lethal junctional epidermolysis bullosa, Lab Invest, 64, 85
Giurdanella, 2019, Keratinocyte footprint assay discriminates antilaminin-332 pemphigoid from all other forms of pemphigoid diseases, Br J Dermatol, 2, 373
Chan, 1997, Laminin-6 and laminin-5 are recognized by autoantibodies in a subset of cicatricial pemphigoid, J Invest Dermatol, 108, 848, 10.1111/1523-1747.ep12292578
Domloge-Hultsch, 1992, Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease, J Clin Invest, 90, 1628, 10.1172/JCI116033
Lazarova, 2008, IgG anti-laminin-332 autoantibodies are present in a subset of patients with mucous membrane, but not bullous, pemphigoid, J Am Acad Dermatol, 58, 951, 10.1016/j.jaad.2008.02.035
Egan, 2001, Anti-epiligrin cicatricial pemphigoid and relative risk for cancer, Lancet, 357, 1850, 10.1016/S0140-6736(00)04971-0
Matsushima, 2004, A case of anti-epiligrin cicatricial pemphigoid associated with lung carcinoma and severe laryngeal stenosis: review of Japanese cases and evaluation of risk for internal malignancy, J Dermatol, 31, 10, 10.1111/j.1346-8138.2004.tb00497.x
Leverkus, 1999, Antiepiligrin cicatricial pemphigoid: an underdiagnosed entity within the spectrum of scarring autoimmune subepidermal bullous diseases?, Arch Dermatol, 135, 1091, 10.1001/archderm.135.9.1091
Terra, 2011, Immunofluorescence serration pattern analysis as a diagnostic criterion in antilaminin-332 mucous membrane pemphigoid: immunopathological findings and clinical experience in 10 Dutch patients, Br J Dermatol, 165, 815, 10.1111/j.1365-2133.2011.10474.x
La Placa, 2019, Mucous membrane pemphigoid-associated malignancies: case series and a brief overview of the literature, Dermatol Pract Concept, 9, 119, 10.5826/dpc.0902a07
Carter, 1991, Epiligrin, a new cell adhesion ligand for integrin alpha 3 beta 1 in epithelial basement membranes, Cell, 65, 599, 10.1016/0092-8674(91)90092-D
Rousselle, 1991, Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments, J Cell Biol, 114, 567, 10.1083/jcb.114.3.567
Koga, 2019, Detachment of keratinocytes at the basement membrane zone caused by inhibitory effect of the antibodies from sera of mucous membrane pemphigoid patients, J Dermatol, 46, 1046, 10.1111/1346-8138.15083
Lazarova, 2000, Human anti-laminin 5 autoantibodies induce subepidermal blisters in an experimental human skin graft model, J Invest Dermatol, 114, 178, 10.1046/j.1523-1747.2000.00829.x
Delmont, 2017, Autoantibodies to nodal isoforms of neurofascin in chronic inflammatory demyelinating polyneuropathy, Brain, 140, 1851, 10.1093/brain/awx124
Lin, 2018, Presence of both anti-contactin 1 and anti-neurofascin 140 antibodies in a case of chronic inflammatory demyelinating polyneuropathy, eNeurologicalSci, 13, 38, 10.1016/j.ensci.2018.11.016
Segelmark, 2018
Thibaud, 2019, Recurrence of Goodpasture syndrome without circulating anti-glomerular basement membrane antibodies after kidney transplant, a case report, BMC Nephrol, 20, 6, 10.1186/s12882-018-1197-6
Lerner, 1967, The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis, J Exp Med, 126, 989, 10.1084/jem.126.6.989
Ohlsson, 2014, Circulating anti-glomerular basement membrane antibodies with predominance of subclass IgG4 and false-negative immunoassay test results in anti-glomerular basement membrane disease, Am J Kidney Dis, 63, 289, 10.1053/j.ajkd.2013.08.032
Sethi, 2007, Linear anti-glomerular basement membrane IgG but no glomerular disease: Goodpasture’s syndrome restricted to the lung, Nephrol Dial Transplant, 22, 1233, 10.1093/ndt/gfl841
Cui, 2007, Antiglomerular basement membrane disease with normal renal function, Kidney Int, 72, 1403, 10.1038/sj.ki.5002525
Qu, 2013, The distribution of IgG subclass deposition on renal tissues from patients with anti-glomerular basement membrane disease, BMC Immunol, 14, 19, 10.1186/1471-2172-14-19
Bruschi, 2011, Direct characterization of target podocyte antigens and auto-antibodies in human membranous glomerulonephritis: alfa-enolase and borderline antigens, J Proteomics, 74, 2008, 10.1016/j.jprot.2011.05.021
Prunotto, 2010, Autoimmunity in membranous nephropathy targets aldose reductase and SOD2, J Am Soc Nephrol, 21, 507, 10.1681/ASN.2008121259
Miles, 1991, Role of cell-surface lysines in plasminogen binding to cells: identification of alpha-enolase as a candidate plasminogen receptor, Biochemistry, 30, 1682, 10.1021/bi00220a034
Kimura, 2017, Circulating antibodies to alpha-enolase and phospholipase A2 receptor and composition of glomerular deposits in Japanese patients with primary or secondary membranous nephropathy, Clin Exp Nephrol, 21, 117, 10.1007/s10157-016-1235-2
Aarli, 2008, Myasthenia gravis in the elderly: is it different?, Ann N Y Acad Sci, 1132, 238, 10.1196/annals.1405.040
Zillikens, 1996, A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone, J Invest Dermatol, 106, 1333, 10.1111/1523-1747.ep12349283
Chen, 1996, Coexistence of psoriasis and an unusual IgG-mediated subepidermal bullous dermatosis: identification of a novel 200-kDa lower lamina lucida target antigen, Br J Dermatol, 134, 340, 10.1111/j.1365-2133.1996.tb07625.x
Kridin, 2019, Anti-p200 pemphigoid: a systematic review, Front Immunol, 10, 2466, 10.3389/fimmu.2019.02466
Patsatsi, 2017, Chronic bullous disease of childhood with IgG reactivity to p200 antigen, Int J Dermatol, 56, 773, 10.1111/ijd.13616
Zillikens, 1996, A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone, J Invest Dermatol, 106, 465, 10.1111/1523-1747.ep12343631
Shimanovich, 2003, The autoantigen of anti-p200 pemphigoid is an acidic noncollagenous N-linked glycoprotein of the cutaneous basement membrane, J Invest Dermatol, 121, 1402, 10.1111/j.1523-1747.2003.12609.x
Wald, 2019, Overlap of bullous, anti-Laminin-332, and anti-p200 pemphigoid with concomitant anti-Contactin-1-positive inflammatory polyneuropathy treated with intravenous immunoglobulins as a manifestation of epitope spreading, JAMA Dermatol, 155, 631, 10.1001/jamadermatol.2018.5536
Dainichi, 2010, From anti-p200 pemphigoid to anti-laminin gamma1 pemphigoid, J Dermatol, 37, 231, 10.1111/j.1346-8138.2009.00793.x
Dainichi, 2009, Anti-laminin gamma-1 pemphigoid, Proc Natl Acad Sci U S A, 106, 2800, 10.1073/pnas.0809230106
Groth, 2011, Development of a simple enzyme-linked immunosorbent assay for the detection of autoantibodies in anti-p200 pemphigoid, Br J Dermatol, 164, 76, 10.1111/j.1365-2133.2010.10056.x
Monshi, 2012, A long-term study of a patient with anti-p200 pemphigoid: correlation of autoantibody levels with disease activity and an example of epitope spreading, Br J Dermatol, 167, 1179, 10.1111/j.1365-2133.2012.11076.x
Vafia, 2012, Pathogenicity of autoantibodies in anti-p200 pemphigoid, PLoS One, 7, 10.1371/journal.pone.0041769
Koga, 2013, An attempt to develop mouse model for anti-laminin gamma1 pemphigoid, J Dermatol Sci, 70, 108, 10.1016/j.jdermsci.2013.01.001
Lamprecht, 2018, Pathogenetic and clinical aspects of anti-neutrophil cytoplasmic autoantibody-associated Vasculitides, Front Immunol, 9, 680, 10.3389/fimmu.2018.00680
Holland, 2004, Anti-neutrophil cytoplasm antibody IgG subclasses in Wegener’s granulomatosis: a possible pathogenic role for the IgG4 subclass, Clin Exp Immunol, 138, 183, 10.1111/j.1365-2249.2004.02566.x
Brouwer, 1991, Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener’s granulomatosis and clinically related disorders, Clin Exp Immunol, 83, 379, 10.1111/j.1365-2249.1991.tb05647.x
Hussain, 2009, Chimeric IgG4 PR3-ANCA induces selective inflammatory responses from neutrophils through engagement of Fcgamma receptors, Immunology, 128, 236, 10.1111/j.1365-2567.2009.03108.x
Chang, 2012, Increased IgG4-positive plasma cells in granulomatosis with Polyangiitis: a diagnostic pitfall of IgG4-related disease, Int J Rheumatol, 2012, 121702, 10.1155/2012/121702
Bando, 2015, A diagnostic pitfall in IgG4-related hypophysitis: infiltration of IgG4-positive cells in the pituitary of granulomatosis with polyangiitis, Pituitary, 18, 722, 10.1007/s11102-015-0650-9
Kaushik, 2018, Medical mirroring: granulomatosis with polyangiitis (formerly Wegener's) mimicking immunoglobulin-G4 related disease, Int J Rheum Dis, 21, 885, 10.1111/1756-185X.12687
Della-Torre, 2016, Antineutrophil cytoplasmic antibody positivity in IgG4-related disease: a case report and review of the literature, Medicine (Baltimore), 95, 10.1097/MD.0000000000004633
Abbass, 2019, Granulomatosis with polyangiitis in a patient with biopsy-proven IgG4-related pulmonary disease and coincident small cell lung cancer, BMJ Case Rep, 12, 10.1136/bcr-2018-226280
Massey, 2017, IgG4-related hypertrophic pachymeningitis coexpressing antineutrophil cytoplasmic antibodies, Neurol Neuroimmunol Neuroinflam, 4, e341, 10.1212/NXI.0000000000000341
Watanabe, 2018, Rapidly progressive glomerulonephritis caused by overlap syndrome of IgG4-related tubulointerstitial nephritis and myeloperoxidase-antineutrophil cytoplasmic antibody-associated necrotising glomerulonephritis, Clin Exp Rheumatol, 36, 172
Su, 2017, Concurrent IgG4-related tubulointerstitial nephritis and IgG4 myeloperoxidase-anti-neutrophil cytoplasmic antibody positive crescentic glomerulonephritis: a case report, Medicine (Baltimore), 96, 10.1097/MD.0000000000006707
Touge, 2017, A case of proteinase 3 anti-neutrophil cytoplasmic antibody (PR3-ANCA) positive/IgG4-related lung disease, Respir Med Case Rep, 20, 92
Danlos, 2017, Antineutrophil cytoplasmic antibody-associated vasculitides and IgG4-related disease: A new overlap syndrome, Autoimmun Rev, 16, 1036, 10.1016/j.autrev.2017.07.020
Perez Alamino, 2013, IgG4-associated vasculitis, Curr Rheumatol Rep, 15, 348, 10.1007/s11926-013-0348-9
Kawashima, 2019, Consideration concerning similarities and differences between ANCA-associated vasculitis and IgG-4-related diseases: case series and review of literature, Immunol Res, 67, 99, 10.1007/s12026-019-9070-7
Goulabchand, 2017, Comment on the article entitled “Antineutrophil cytoplasmic antibody-associated vasculitides and IgG4-related disease: a new overlap syndrome”, Autoimmun Rev, 16, 1036, 10.1016/j.autrev.2017.07.020
Yoo, 2019, No overlap between IgG4-related disease and microscopic polyangiitis and granulomatosis with polyangiitis despite elevated serum IgG4 at diagnosis: a retrospective monocentric study, Clin Rheumatol, 38, 1147, 10.1007/s10067-018-4402-x
Al-Soudi, 2019, IgG4:IgG RNA ratio differentiates active disease from remission in granulomatosis with polyangiitis: a new disease activity marker? A cross-sectional and longitudinal study, Arthritis Res Ther, 21, 43, 10.1186/s13075-018-1806-6
Tominaga, 2018, Anti-neutrophil cytoplasmic antibody-associated glomerulonephritis with detection of myeloperoxidase and phospholipase A2 receptor in membranous nephropathy-lesions: report of two patients with microscopic polyangiitis, BMC Nephrol, 19, 120, 10.1186/s12882-018-0922-5
Zou, 2015, Clinical and immunologic characteristics of patients with ANCA-associated glomerulonephritis combined with membranous nephropathy: a retrospective cohort study in a single Chinese center, Medicine (Baltimore), 94, 10.1097/MD.0000000000001472
Stump, 2019, Concurrent mucous membrane pemphigoid and membranous glomerulonephritis in a patient with autoantibodies targeting the 1080 region of collagen XVII, Br J Dermatol, 4, 835, 10.1111/bjd.17923
Zheng, 2019, Characteristics of IgG subclasses and complement deposition in BP230-type bullous pemphigoid, J Eur Acad Dermatol Venereol, 33, 595, 10.1111/jdv.15325
Diaz, 1990, Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome, J Clin Invest, 86, 1088, 10.1172/JCI114812
Stanley, 1981, Characterization of bullous pemphigoid antigen: a unique basement membrane protein of stratified squamous epithelia, Cell, 24, 897, 10.1016/0092-8674(81)90115-X
Sitaru, 2007, The relevance of the IgG subclass of autoantibodies for blister induction in autoimmune bullous skin diseases, Arch Dermatol Res, 299, 1, 10.1007/s00403-007-0734-0
Zhou, 2016, Serum levels of immunoglobulins G1 and G4 targeting the non-collagenous 16A domain of BP180 reflect bullous pemphigoid activity and predict bad prognosis, J Dermatol, 43, 141, 10.1111/1346-8138.13051
Liu, 1995, The role of complement in experimental bullous pemphigoid, J Clin Invest, 95, 1539, 10.1172/JCI117826
Chen, 2001, Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid, J Clin Invest, 108, 1151, 10.1172/JCI11494
Liu, 2000, A critical role for neutrophil elastase in experimental bullous pemphigoid, J Clin Invest, 105, 113, 10.1172/JCI3693
Hiroyasu, 2013, Bullous pemphigoid IgG induces BP180 internalization via a macropinocytic pathway, Am J Pathol, 182, 828, 10.1016/j.ajpath.2012.11.029
Iwata, 2009, IgG from patients with bullous pemphigoid depletes cultured keratinocytes of the 180-kDa bullous pemphigoid antigen (type XVII collagen) and weakens cell attachment, J Invest Dermatol, 129, 919, 10.1038/jid.2008.305
Ujiie, 2014, Bullous pemphigoid autoantibodies directly induce blister formation without complement activation, J Immunol, 193, 4415, 10.4049/jimmunol.1400095
Zuo, 2016, IgG4 autoantibodies are inhibitory in the autoimmune disease bullous pemphigoid, J Autoimmun, 73, 111, 10.1016/j.jaut.2016.06.019
Boronat, 2013, Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels, Ann Neurol, 73, 120, 10.1002/ana.23756
Hara, 2017, DPPX antibody-associated encephalitis: Main syndrome and antibody effects, Neurology, 88, 1340, 10.1212/WNL.0000000000003796
Piepgras, 2015, Anti-DPPX encephalitis: pathogenic effects of antibodies on gut and brain neurons, Neurology, 85, 890, 10.1212/WNL.0000000000001907
Lutt, 2018, High prevalence and functional effects of serum antineuronal antibodies in patients with gastrointestinal disorders, Neurogastroenterol Motil, 30, 10.1111/nmo.13292
Gelpi, 2016, Neuropathological criteria of anti-IgLON5-related tauopathy, Acta Neuropathol, 132, 531, 10.1007/s00401-016-1591-8
Cagnin, 2017, Microglial and neuronal TDP-43 pathology in anti-IgLON5-related Tauopathy, J Alzheimer’s Dis, 59, 13, 10.3233/JAD-170189
Sabater, 2014, A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study, Lancet Neurol, 13, 575, 10.1016/S1474-4422(14)70051-1
Schoberl, 2018, IgLON5: a case with predominant cerebellar tau deposits and leptomeningeal inflammation, Neurology, 91, 180, 10.1212/WNL.0000000000005859
Nagamine, 1997, Positional cloning of the APECED gene, Nat Genet, 17, 393, 10.1038/ng1297-393
Meyer, 2016, AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies, Cell, 166, 582, 10.1016/j.cell.2016.06.024
Kisand, 2010, Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines, J Exp Med, 207, 299, 10.1084/jem.20091669
Karner, 2016, IL-6-specific autoantibodies among APECED and thymoma patients, Immun Inflamm Dis, 4, 235, 10.1002/iid3.109
Bichele, 2018, IL-22 neutralizing autoantibodies impair fungal clearance in murine oropharyngeal candidiasis model, Eur J Immunol, 48, 464, 10.1002/eji.201747209
Gavanescu, 2008, B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: a therapeutic approach for APECED patients, Proc Natl Acad Sci U S A, 105, 13009, 10.1073/pnas.0806874105
Ossart, 2018, Breakdown of immune tolerance in AIRE-deficient rats induces a severe autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy-like autoimmune disease, J Immunol, 201, 874, 10.4049/jimmunol.1701318