A multi-approach peptidomic analysis of hen egg white reveals novel putative bioactive molecules

Kovacs-Nolan, 2005, Advances in the value of eggs and egg components for human health, J. Agric. Food Chem., 53, 8421, 10.1021/jf050964f Nimalaratne, 2015, Hen egg as an antioxidant food commodity: a review, Nutrients, 7, 8274, 10.3390/nu7105394 Chang, 2018, Egg proteins: fractionation, bioactive peptides and allergenicity, J. Agric. Food Chem., 98, 5547, 10.1002/jsfa.9150 Mann, 2007, The chicken egg white proteome, Proteomics, 7, 3558, 10.1002/pmic.200700397 Mann, 2007, Phosphoproteins of the chicken eggshell calcified layer, Proteomics, 7, 106, 10.1002/pmic.200600635 Mann, 2011, In-depth analysis of the chicken egg white proteome using an LTQ Orbitrap Velos, Proteome Sci., 9, 7, 10.1186/1477-5956-9-7 Omana, 2011, Proteomic analysis of egg white proteins during storage, Proteomics, 11, 144, 10.1002/pmic.201000168 Qiu, 2012, Comparative proteomic analysis of egg white proteins under various storage temperatures, J. Agric. Food Chem., 60, 7746, 10.1021/jf302100m Makkar, 2015, Chicken eggshell membrane associated proteins and peptides, J. Agric. Food Chem., 63, 9888, 10.1021/acs.jafc.5b04266 Guyot, 2016, Proteomic analysis of egg white heparin-binding proteins: towards the identification of natural antibacterial molecules, Sci. Rep., 6, 10.1038/srep27974 He, 2017, Proteomic comparison by iTRAQ combined with mass spectrometry of egg white proteins in laying hens (Gallus gallus) fed with soybean meal and cottonseed meal, PLoS One, 12, 10.1371/journal.pone.0182886 Grootaert, 2017, Egg-derived bioactive peptides with ACE-inhibitory properties: a literature update, Food Funct., 8, 3847, 10.1039/C7FO00839B Liu, 2018, Bioactive peptides derived from egg proteins: a review, Crit. Rev. Food Sci. Nutr., 58, 2508, 10.1080/10408398.2017.1329704 Liao, 2018, Egg protein-derived bioactive peptides: preparation, efficacy, and absorption, Adv. Food Nutr. Res., 85, 1, 10.1016/bs.afnr.2018.02.001 Miguel, 2004, Angiotensin I–converting enzyme inhibitory activity of peptides derived from egg white proteins by enzymatic hydrolysis, J. Food Prot., 67, 1914, 10.4315/0362-028X-67.9.1914 Miguel, 2007, Antihypertensive, ACE-inhibitory and vasodilator properties of an egg white hydrolysate: effect of a simulated intestinal digestion, Food Chem., 104, 163, 10.1016/j.foodchem.2006.11.016 Majumder, 2009, Angiotensin i converting enzyme inhibitory peptides from simulated in vitro gastrointestinal digestion of cooked eggs, J. Agric. Food Chem., 57, 471, 10.1021/jf8028557 Nimalaratne, 2015, Purification and characterization of antioxidant peptides from enzymatically hydrolyzed chicken egg white, Food Chem., 188, 467, 10.1016/j.foodchem.2015.05.014 Jahandideh, 2018, Purification and identification of adipogenic-differentiating peptides from egg white hydrolysate, Food Chem., 259, 25, 10.1016/j.foodchem.2018.03.099 Wang, 2018, Effect of different heat treatments on in vitro digestion of egg white proteins and identification of bioactive peptides in digested products, J. Food Sci., 83, 1140, 10.1111/1750-3841.14107 Zhang, 2019, Isolation and identification of peptides from simulated gastrointestinal digestion of preserved egg white and their anti-inflammatory activity in TNF-α-induced Caco-2 cells, J. Nutr. Biochem., 63, 44, 10.1016/j.jnutbio.2018.09.019 Arena, 2018, An extensive description of the peptidomic repertoire of the hen egg yolk plasma, J. Agric. Food Chem., 66, 3239, 10.1021/acs.jafc.8b01183 Sassi, 2015, MALDI-TOF-MS platform for integrated proteomic and Peptidomic profiling of milk samples allows rapid detection of food adulterations, J. Agric. Food Chem., 63, 6157, 10.1021/acs.jafc.5b02384 Zhu, 2017, Reverse chemical ecology: olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles, Proc. Natl. Acad. Sci. U. S. A., 114, E9802, 10.1073/pnas.1711437114 Aluko, 2015, Antihypertensive peptides from food proteins, Ann. Rev. Food Sci. Technol., 6, 235, 10.1146/annurev-food-022814-015520 Lee, 2017, Antihypertensive peptides from animal products, marine organisms, and plants, Food Chem., 228, 506, 10.1016/j.foodchem.2017.02.039 Hartmann, 2007, Food-derived peptides with biological activity: from research to food applications, Curr. Opin. Biotechnol., 18, 163, 10.1016/j.copbio.2007.01.013 Lafarga, 2014, Identification of novel dipeptidyl peptidase-IV and angiotensin-I- converting enzyme inhibitory peptides from meat proteins using in silico analysis, Peptides, 59, 53, 10.1016/j.peptides.2014.07.005 Abeyrathne, 2018, Antioxidant, angiotensin-converting enzyme inhibitory activity and other functional properties of egg white proteins and their derived peptides - a review, Poultry Sci., 97, 1462, 10.3382/ps/pex399 Huang, 2013, Bioactive natural constituents from food sources-potential use in hypertension prevention and treatment, Crit. Rev. Food Sci. Nutr., 53, 615, 10.1080/10408398.2010.550071 Bauchart, 2007, Peptides reproducibly released by in vivo digestion of beef meat and trout flesh in pigs, Br. J. Nutr., 98, 1187, 10.1017/S0007114507761810 Albenzio, 2017, Bioactive peptides in animal food products, Foods, 6, 35, 10.3390/foods6050035 Srinivasan, 2014, Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation, Drug Des. Devel. Ther., 8, 2409, 10.2147/DDDT.S59722 Vitali, 2015, Proline-rich peptides: multifunctional bioactive molecules as new potential therapeutic drugs, Curr. Protein Pept. Sci., 16, 147, 10.2174/1389203716666150102110817 Gupta, 2017, Prediction of anti-inflammatory proteins/peptides: an in silico approach, J. Transl. Med., 15, 1, 10.1186/s12967-016-1103-6 Zou, 2016, The structure-activity relationship of the antioxidant peptides from natural proteins, Molecules, 21, 72, 10.3390/molecules21010072 Daliri, 2017, Bioactive Peptides, Foods, 6, 32, 10.3390/foods6050032 Watanabe, 1998, Antitumor effects of pronase-treated fragments, glycopeptides, from ovomucin in hen egg white in a double grafted tumor system, J. Agric. Food Chem., 46, 3033, 10.1021/jf9800615 Su, 2010, Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancer, Proc. Natl. Acad. Sci. U. S. A., 107, 19997, 10.1073/pnas.1009010107 Yu, 2011, Novel peptides derived from egg white protein inhibiting alpha-glucosidase, Food Chem., 129, 1376, 10.1016/j.foodchem.2011.05.067 Schalla, 2018, Current understanding of the role of nesfatin-1, J. Endocr. Soc., 2, 1188, 10.1210/js.2018-00246 Song, 2019, Effects of dietary supplementation of microencapsulated Enterococcus fecalis and the extract of amellia oleifera seed on laying performance, egg quality, serum biochemical parameters, and cecal microflora diversity in laying hens, Poult. Sci., 98, 2880, 10.3382/ps/pez033 Lee, 2019, Characterization of microbial communities in the chicken oviduct and the origin of chicken embryo gut microbiota, Sci. Rep., 9 Yan, 2019, Effects of probiotic supplementation on performance traits, bone mineralization, cecal microbial composition, cytokines and corticosterone in laying hens, Animal, 13, 33, 10.1017/S175173111800109X Wang, 2017, Effects of dietary Bacillus licheniformis on gut physical barrier, immunity, and reproductive hormones of laying hens, Probiotics Antimicrob. Proteins, 9, 292, 10.1007/s12602-017-9252-3