Functional TNFα gene silencing mediated by polyethyleneimine/TNFα siRNA nanocomplexes in inflamed colon

Biomaterials - Tập 32 - Trang 1218-1228 - 2011
Hamed Laroui1, Arianne L. Theiss1, Yutao Yan1, Guillaume Dalmasso1, Hang T.T. Nguyen1, Shanthi V. Sitaraman1, Didier Merlin1,2
1Department of Medicine, Division of Digestive Diseases, Emory University, Atlanta, GA, United States
2Veterans Affairs Medical Center, Decatur, GA, United States

Tài liệu tham khảo

Holtmann, 2005, Anti-TNF strategies in stenosing and fistulizing Crohn’s disease, Int J Colorectal Dis, 20, 1, 10.1007/s00384-004-0634-0 de Vries, 2009, High-fat feeding redirects cytokine responses and decreases allergic airway eosinophilia, Clin Exp Allergy, 39, 731, 10.1111/j.1365-2222.2008.03179.x D’Haens, 2003, Anti-TNF therapy for Crohn’s disease, Curr Pharm Des, 9, 289, 10.2174/1381612033391982 Toub, 2006, Efficacy of siRNA nanocapsules targeted against the EWS-Fli1 oncogene in Ewing sarcoma, Pharm Res, 23, 892, 10.1007/s11095-006-9901-9 Lieberman, 2003, Interfering with disease: opportunities and roadblocks to harnessing RNA interference, Trends Mol Med, 9, 397, 10.1016/S1471-4914(03)00143-6 Meade, 2007, Exogenous siRNA delivery using peptide transduction domains/cell penetrating peptides, Adv Drug Deliv Rev, 59, 134, 10.1016/j.addr.2007.03.004 Schiffelers, 2004, Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle, Nucleic Acids Res, 32, e149, 10.1093/nar/gnh140 Raper, 2005, Gene therapy: the good, the bad, and the ugly, Surgery, 137, 487, 10.1016/j.surg.2004.10.014 Farokhzad, 2004, Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells, Cancer Res, 64, 7668, 10.1158/0008-5472.CAN-04-2550 Gunther, 2005, Specific targets in tumor tissue for the delivery of therapeutic genes, Curr Med Chem Anticancer Agents, 5, 157, 10.2174/1568011053174855 Hood, 2002, Tumor regression by targeted gene delivery to the neovasculature, Science, 296, 2404, 10.1126/science.1070200 Kim, 2004, Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis, Am J Pathol, 165, 2177, 10.1016/S0002-9440(10)63267-1 Pardridge, 2004, Intravenous, non-viral RNAi gene therapy of brain cancer, Expert Opin Biol Ther, 4, 1103, 10.1517/14712598.4.7.1103 Fattal, 1998, Biodegradable polyalkylcyanoacrylate nanoparticles for the delivery of oligonucleotides, J Control Release, 53, 137, 10.1016/S0168-3659(97)00246-0 Lamprecht, 2001, Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa, Pharm Res, 18, 788, 10.1023/A:1011032328064 Laroui, 2010, Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model, Gastroenterology, 138, 843, 10.1053/j.gastro.2009.11.003 Zambaux, 1998, Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion method, J Control Release, 50, 31, 10.1016/S0168-3659(97)00106-5 Ngamwongsatit, 2008, WST-1-based cell cytotoxicity assay as a substitute for MTT-based assay for rapid detection of toxigenic Bacillus species using CHO cell line, J Microbiol Methods, 73, 211, 10.1016/j.mimet.2008.03.002 Siegmund, 2001, IL-1 beta -converting enzyme (caspase-1) in intestinal inflammation, Proc Natl Acad Sci U S A, 98, 13249, 10.1073/pnas.231473998 Liberman, 1969, Mechanism of coupling of oxidative phosphorylation and the membrane potential of mitochondria, Nature, 222, 1076, 10.1038/2221076a0 Ketterer, 1971, Transport mechanism of hydrophobic ions across through lipid bilayers, J Memb Biol, 5, 225, 10.1007/BF01870551 Yamanaka, 2008, Engineering strategies to enhance nanoparticle-mediated oral delivery, J Biomater Sci Polym Ed, 19, 1549, 10.1163/156856208786440479 Del Cacho, 2008, Isolation of chicken follicular dendritic cells, J Immunol Methods, 334, 59, 10.1016/j.jim.2008.02.001 Shankar, 2010, Comparative characterization of cultures of primary human macrophages or dendritic cells relevant to biomaterial studies, J Biomed Mater Res A, 92, 791, 10.1002/jbm.a.32406 Maruyama, 2004, Novel receptor-mediated gene delivery system comprising plasmid/protamine/sugar-containing polyanion ternary complex, Biomaterials, 25, 3267, 10.1016/j.biomaterials.2003.10.004 Akinc, 2005, Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis, J Gene Med, 7, 657, 10.1002/jgm.696