Evidence for thymic function in the elderly

Steinmann, 1986, Changes in the human thymus during aging, Current Topics In Pathology, 75, 43, 10.1007/978-3-642-82480-7_2

Steinmann, 1985, The involution of the aging human thymic epithelium is independent of puberty, Scand. J. Immunol., 22, 563, 10.1111/j.1365-3083.1985.tb01916.x

Kendall, 1980, The weight of the human thymus gland at necropsy, J. Anat., 131, 485

Steinmann, 1984, Immunohistological demonstration of terminal transferase (TdT) in the age-involuted human thymus, Immunobiology, 166, 45, 10.1016/S0171-2985(84)80142-4

Jamieson, 1999, Generation of functional thymocytes in the human adult, Immunity, 10, 569, 10.1016/S1074-7613(00)80056-4

Lindsey, 1994, Repeated treatment with chimeric anti-CD4 anitbody in multiple sclerosis, Ann. Neurol., 36, 183, 10.1002/ana.410360210

Mackall, 1995, Age, thymopoiesis, and CD4+ T-lymphocyte regeneration after intensive chemotherapy, N. Engl. J. Med., 332, 143, 10.1056/NEJM199501193320303

McCune, 1998, High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection, J. Clin. Invest., 101, 2301, 10.1172/JCI2834

Haynes, 1983, Effect of thymectomy on peripheral lymphocyte subsets in myasthenia gravis: selective effect on T-cells in patients with thymic atrophy, J. Immunol, 131, 773, 10.4049/jimmunol.131.2.773

Watanebe, 1997, Long-term depletion of naive T cells in patients treated for Hodgkin’s disease, Blood, 90, 3662, 10.1182/blood.V90.9.3662

Brearley, 1987, Immunodeficiency following neonatal thymectomy in man, Clin. Exp. Immunol., 70, 322

Ramos, 1996, Phenotypic and functional evaluation of natural killer cells in thymectomized children, Clin. Immunol. Immunopathol., 81, 277, 10.1006/clin.1996.0189

Zollinger, 1964, Effect of thymectomy on skin-homograft survival in children, N. Engl. J. Med., 270, 707, 10.1056/NEJM196404022701404

George, 1996, Thymic involution with aging: obsolescence or good housekeeping?, Immunol. Today, 17, 267, 10.1016/0167-5699(96)80543-3

Storek, 1995, T cell reconsitution after bone marrow transplantation into adult patients does not resemble T cell development in early life, Bone Mar. Transpl., 16, 416

Weinberg, 1995, The effect of thymic function on immunocompetence following bone marrow transplantation, Biology of Blood and Marrow Transplantation, 1, 18

Leino, 1991, The reappearance of 10 differentiation antigens on peripheral blood lymphocytes after allogeneic bone marrow transplantation, Bone Mar. Transpl., 8, 339

Janeway, 1994, The thymus and the development of T lymphocytes, 6:1

Sleckman, 1997, Function of the TCRα enhancer in αβ and γδ T cells, Immunity, 7, 505, 10.1016/S1074-7613(00)80372-6

Kong, 1998, Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation, Immunity, 8, 97, 10.1016/S1074-7613(00)80462-8

Jamieson, 1997, High viral burden and rapid CD4+ cell depletion in human immunodeficiency virus type 1-infected SCID-hu mice suggest direct viral killing of thymocytes in vivo, J. Virol., 71, 8245, 10.1128/JVI.71.11.8245-8253.1997

Verschuren, 1998, T-cell receptor Vδ-Jα rearrangements in T-cell receptor-δ gene deletion, Immunology, 93, 208, 10.1046/j.1365-2567.1998.00417.x

Verschuren, 1997, Preferential rearrangements of the T cell receptor-δ-deleting elements in human T cells, J. Immunol., 158, 1208, 10.4049/jimmunol.158.3.1208

Douek, 1998, Changes in thymic function with age and during the treatment of HIV infection, Nature, 396, 690, 10.1038/25374

Cossarizza, 1992, Age-related imbalance of virgin (CD45RA+) and memory (CD45R0+) cells between CD4+ and CD8+ T lymphocytes in humans: a study from newborns to centenarians, J. Immunol. Res., 4, 118