iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy
Tài liệu tham khảo
Badman, 2009, Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis, Endocrinology, 150, 4931, 10.1210/en.2009-0532
Baggio, 2007, Biology of incretins: GLP-1 and GIP, Gastroenterology, 132, 2131, 10.1053/j.gastro.2007.03.054
Brestoff, 2015, Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity, Nature, 519, 242, 10.1038/nature14115
Brigl, 2004, CD1: antigen presentation and T cell function, Annu. Rev. Immunol., 22, 817, 10.1146/annurev.immunol.22.012703.104608
Cousin, 1992, Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization, J. Cell Sci., 103, 931, 10.1242/jcs.103.4.931
Enerbäck, 2009, The origins of brown adipose tissue, N. Engl. J. Med., 360, 2021, 10.1056/NEJMcibr0809610
Enerbäck, 1997, Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese, Nature, 387, 90, 10.1038/387090a0
Fisher, 2012, FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis, Genes Dev., 26, 271, 10.1101/gad.177857.111
Gaich, 2013, The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes, Cell Metab., 18, 333, 10.1016/j.cmet.2013.08.005
Hadjiyanni, 2010, Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells, Diabetologia, 53, 730, 10.1007/s00125-009-1643-x
Hams, 2013, Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice, J. Immunol., 191, 5349, 10.4049/jimmunol.1301176
Hanssen, 2015, Serum FGF21 levels are associated with brown adipose tissue activity in humans, Sci. Rep., 5, 10275, 10.1038/srep10275
Harder, 2004, The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes, Diabetes Care, 27, 1915, 10.2337/diacare.27.8.1915
Himms-Hagen, 1994, Effect of CL-316,243, a thermogenic beta 3-agonist, on energy balance and brown and white adipose tissues in rats, Am. J. Physiol., 266, R1371
Hogan, 2011, Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis, Diabetologia, 54, 2745, 10.1007/s00125-011-2232-3
Hogan, 2014, Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus, Diabetologia, 57, 781, 10.1007/s00125-013-3145-0
Holland, 2013, An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice, Cell Metab., 17, 790, 10.1016/j.cmet.2013.03.019
Huh, 2013, A novel function of adipocytes in lipid antigen presentation to iNKT cells, Mol. Cell. Biol., 33, 328, 10.1128/MCB.00552-12
Ji, 2012, Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4, J. Biol. Chem., 287, 24378, 10.1074/jbc.M112.371807
Kharitonenkov, 2013, Inventing new medicines: the FGF21 story, Mol. Metab., 3, 221, 10.1016/j.molmet.2013.12.003
Kharitonenkov, 2005, FGF-21 as a novel metabolic regulator, J. Clin. Invest., 115, 1627, 10.1172/JCI23606
Lee, 2015, Activated type 2 innate lymphoid cells regulate beige fat biogenesis, Cell, 160, 74, 10.1016/j.cell.2014.12.011
Lockie, 2012, Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling, Diabetes, 61, 2753, 10.2337/db11-1556
Lovshin, 2009, Incretin-based therapies for type 2 diabetes mellitus, Nat. Rev. Endocrinol., 5, 262, 10.1038/nrendo.2009.48
Lynch, 2009, Invariant NKT cells and CD1d(+) cells amass in human omentum and are depleted in patients with cancer and obesity, Eur. J. Immunol., 39, 1893, 10.1002/eji.200939349
Lynch, 2012, Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production, Immunity, 37, 574, 10.1016/j.immuni.2012.06.016
Lynch, 2015, Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue, Nat. Immunol., 16, 85, 10.1038/ni.3047
Molofsky, 2013, Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages, J. Exp. Med., 210, 535, 10.1084/jem.20121964
Nguyen, 2011, Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis, Nature, 480, 104, 10.1038/nature10653
Nonogaki, 2014, Liraglutide suppresses obesity and hyperglycemia associated with increases in hepatic fibroblast growth factor 21 production in KKAy mice, BioMed Res. Int., 2014, 751930, 10.1155/2014/751930
O’Shea, 1996, A role for central glucagon-like peptide-1 in temperature regulation, Neuroreport, 7, 830, 10.1097/00001756-199602290-00035
Qiu, 2014, Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat, Cell, 157, 1292, 10.1016/j.cell.2014.03.066
Samms, 2015, Discrete aspects of FGF21 in vivo pharmacology do not require UCP1, Cell Rep., 11, 991, 10.1016/j.celrep.2015.04.046
Schipper, 2012, Natural killer T cells in adipose tissue prevent insulin resistance, J. Clin. Invest., 122, 3343, 10.1172/JCI62739
Turton, 1996, A role for glucagon-like peptide-1 in the central regulation of feeding, Nature, 379, 69, 10.1038/379069a0
van Can, 2014, Effects of the once-daily GLP-1 analog liraglutide on gastric emptying, glycemic parameters, appetite and energy metabolism in obese, non-diabetic adults, Int. J. Obes., 38, 784, 10.1038/ijo.2013.162
Wang, 2011, Health and economic burden of the projected obesity trends in the USA and the UK, Lancet, 378, 815, 10.1016/S0140-6736(11)60814-3
Yang, 2012, Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance, PLoS ONE, 7, e48392, 10.1371/journal.pone.0048392