Angiography reveals novel features of the retinal vasculature in healthy and diabetic mice

Ali Rahman, 2011, In vivo monitoring of VEGF-induced retinal damage in the Kimba mouse model of retinal neovascularization, Curr. Eye Res., 36, 654, 10.3109/02713683.2010.551172 Armulik, 2011, Pericytes: developmental, physiological, and pathological perspectives, problems, and promises, Dev. Cell., 21, 193, 10.1016/j.devcel.2011.07.001 Barone, 1996, Comparative anatomy of domestic mammals, Angiology, 5, 14 Chen, 2009, Suppression of retinal neovascularization by erythropoietin siRNA in a mouse model of proliferative retinopathy, Invest. Ophthalmol. Vis. Sci., 50, 1329, 10.1167/iovs.08-2521 Cheung, 2005, Aldose reductase deficiency prevents diabetes-induced blood-retinal barrier breakdown, apoptosis, and glial reactivation in the retina of db/db mice, Diabetes, 54, 3119, 10.2337/diabetes.54.11.3119 Cheung, 2010, Diabetic retinopathy, Lancet, 376, 124, 10.1016/S0140-6736(09)62124-3 Gelse, 2003, Collagens – structure, function, and biosynthesis, Adv. Drug Deliv. Rev., 55, 1531, 10.1016/j.addr.2003.08.002 Hammes, 2002, Pericytes and the pathogenesis of diabetic retinopathy, Diabetes, 51, 3107, 10.2337/diabetes.51.10.3107 Han, 2013, Retinal angiogenesis in the Ins2(Akita) mouse model of diabetic retinopathy, Invest. Ophthalmol. Vis. Sci., 54, 574, 10.1167/iovs.12-10959 Hughes, 2004, Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo, Invest. Ophthalmol. Vis. Sci., 45, 2795, 10.1167/iovs.03-1312 Ito, 1999, Regression of the hyaloid vessels and pupillary membrane of the mouse, Anat. Embryol. Berl., 200, 403, 10.1007/s004290050289 Joussen, 2004, A central role for inflammation in the pathogenesis of diabetic retinopathy, FASEB J. Off. Publ. Fed. Am. Soc. Exp. Biol., 18, 1450 Kivela, 1998, Structure, development and function of cytoskeletal elements in non-neuronal cells of the human eye, Prog. Retin. Eye Res., 17, 385, 10.1016/S1350-9462(98)00001-9 McLenachan, 2013, Absence of clinical correlates of diabetic retinopathy in the Ins2(Akita) retina, Clin. Exp. Ophthalmol., 41, 582, 10.1111/ceo.12084 McMenamin, 2000, Optimal methods for preparation and immunostaining of iris, ciliary body, and choroidal wholemounts, Invest. Ophthalmol. Vis. Sci., 41, 3043 Mendes-Jorge, 2012, Intercapillary bridging cells: immunocytochemical characteristics of cells that connect blood vessels in the retina, Exp. Eye Res., 98, 79, 10.1016/j.exer.2012.03.010 Michaelson, 1954, Retinal circulation in man and animals, South. Med. J., 47, 983, 10.1097/00007611-195410000-00029 Okabe, 1997, 'Green mice' as a source of ubiquitous green cells, FEBS Lett., 407, 313, 10.1016/S0014-5793(97)00313-X Paques, 2007, Panretinal, high-resolution color photography of the mouse fundus, Invest. Ophthalmol. Vis. Sci., 48, 2769, 10.1167/iovs.06-1099 Paques, 2006, High resolution fundus imaging by confocal scanning laser ophthalmoscopy in the mouse, Vis. Res., 46, 1336, 10.1016/j.visres.2005.09.037 Paques, 2003, Structural and hemodynamic analysis of the mouse retinal microcirculation, Invest. Ophthalmol. Vis. Sci., 44, 4960, 10.1167/iovs.02-0738 Pfister, 2008, Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy, Diabetes, 57, 2495, 10.2337/db08-0325 Rakoczy, 2010, Characterization of a mouse model of hyperglycemia and retinal neovascularization, Am. J. Pathol., 177, 2659, 10.2353/ajpath.2010.090883 Ramos, 2013, Mimicking microvascular alterations of human diabetic retinopathy: a challenge for the mouse models, Curr. Med. Chem., 20, 3200, 10.2174/09298673113209990028 Ritter, 2005, Three-dimensional in vivo imaging of the mouse intraocular vasculature during development and disease, Invest. Ophthalmol. Vis. Sci., 46, 3021, 10.1167/iovs.05-0153 Robinson, 1992, Retinal vein occlusion, Am. Fam. Physician, 45, 2661 Saint-Geniez, 2004, Development and pathology of the hyaloid, choroidal and retinal vasculature, Int. J. Dev. Biol., 48, 1045, 10.1387/ijdb.041895ms Sarks, 1997, Morphology of early choroidal neovascularisation in age-related macular degeneration: correlation with activity, Eye Lond. Engl., 11, 515 Schallek, 2013, Morphology and topography of retinal pericytes in the living mouse retina using in vivo adaptive optics imaging and ex vivo characterization, Invest. Ophthalmol. Vis. Sci., 54, 8237, 10.1167/iovs.13-12581 Serjeant, 1986, Blood rheology and proliferative retinopathy in homozygous sickle cell disease, Br. J. Ophthalmol., 70, 522, 10.1136/bjo.70.7.522 Simon, 2013, A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains, Genome Biol., 14, R82, 10.1186/gb-2013-14-7-r82 Skalli, 1989, Alpha-smooth muscle actin, a differentiation marker of smooth muscle cells, is present in microfilamentous bundles of pericytes, J. Histochem. Cytochem. Off. J. Histochem. Soc., 37, 315, 10.1177/37.3.2918221 Smith, 2003, Pathogenesis of retinopathy of prematurity, Semin. Neonatol., 8, 469, 10.1016/S1084-2756(03)00119-2 Wise, 1971 Yoshioka, 1997, A novel locus, Mody4, distal to D7Mit189 on chromosome 7 determines early-onset NIDDM in nonobese C57BL/6 (Akita) mutant mice, Diabetes, 46, 887, 10.2337/diab.46.5.887 Zhi, 2014, Noninvasive imaging of retinal morphology and microvasculature in obese mice using optical coherence tomography and optical microangiography, Invest. Ophthalmol. Vis. Sci., 55, 1024, 10.1167/iovs.13-12864 Zudaire, 2011, A computational tool for quantitative analysis of vascular networks, PLoS One, 6, e27385, 10.1371/journal.pone.0027385