The function of PTB domain proteins

Pawson, 1997, Signaling through scaffold, anchoring, and adaptor proteins, Science, 278, 2075, 10.1126/science.278.5346.2075 Bork, 1997, Cytoplasmic signalling domains: The next generation, Trends Biochem Sci, 22, 296, 10.1016/S0968-0004(97)01084-0 Blaikie, 1994, A region in Shc distinct from the SH2 domain can bind tyrosine phosphorylated growth factor receptors, J Biol Chem, 269, 32031, 10.1016/S0021-9258(18)31593-X Gustafson, 1995, Phosphotyrosine-dependent interaction of Shc and IRS-1 with the NPEY motif of the insulin receptor via a novel (non-SH2) domain, Mol Cell Biol, 15, 2500, 10.1128/MCB.15.5.2500 Kavanaugh, 1994, An alternative to SH2 domains for binding tyrosine-phosphorylated proteins, Science, 266, 1862, 10.1126/science.7527937 Margolis, 1995, The use of tyrosine-phosphorylated proteins to screen bacterial expression libraries for SH2 domains, Methods Enzymol, 255, 360, 10.1016/S0076-6879(95)55038-0 Mayer, 1998, Functions of SH2 and SH3 domains, Curr Top Microbiol Immunol, 228, 1 Pelicci, 1992, A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction, Cell, 70, 93, 10.1016/0092-8674(92)90536-L McGlade, 1992, Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases, Proc Natl Acad Sci USA, 89, 8869, 10.1073/pnas.89.19.8869 Rozakis-Adcock, 1992, Association of the Shc and Grb2/Sem5, SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases, Nature, 360, 689, 10.1038/360689a0 Blaikie, 1997, The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation, J Biol Chem, 272, 20671, 10.1074/jbc.272.33.20671 Isakoff, 1996, The Shc PTB/PI domain is required for Shc tyrosine phosphorylation by the insulin receptor (IR) and recognizes an NPXY motif on the IR that is distinct from IRS-1 in vivo, J Biol Chem, 271, 3959, 10.1074/jbc.271.8.3959 Giorgetti-Peraldi, 1997, Cellular effects of phosphotyrosine-binding domain inhibitors on insulin receptor signaling and trafficking, Mol Cell Biol, 17, 1180, 10.1128/MCB.17.3.1180 Borg, 1998, Function of PTB domains, Curr Top Microbiol Immunol, 228, 23 Yajnik, 1996, Identification of residues within the Shc phosphotyrosine binding/phosphotyrosine interaction domain crucial for phosphopeptide interaction, J Biol Chem, 271, 1813, 10.1074/jbc.271.4.1813 Zhou, 1995, Structure and ligand recognition of the phosphotyrosine binding domain of Shc, Nature, 378, 584, 10.1038/378584a0 Lemmon, 1996, PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface, Cell, 85, 621, 10.1016/S0092-8674(00)81022-3 Ravichandran, 1997, Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo, Mol Cell Biol, 17, 5540, 10.1128/MCB.17.9.5540 Sun, 1995, Role of IRS-2 in insulin and cytokine signalling, Nature, 377, 173, 10.1038/377173a0 White, 1998, The IRS-signalling system: A network of docking proteins that mediate insulin action, Mol Cell Biochem, 182, 3, 10.1023/A:1006806722619 Eck, 1996, Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor, Cell, 85, 695, 10.1016/S0092-8674(00)81236-2 Zhou, 1996, Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain, Nat Struct Biol, 3, 388, 10.1038/nsb0496-388 Wolf, 1995, PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities, J Biol Chem, 270, 27407, 10.1074/jbc.270.46.27407 Sharma, 1997, Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes, Mol Cell Biol, 17, 7386, 10.1128/MCB.17.12.7386 Yenush, 1996, The pleckstrin homology domain is the principle link between insulin receptor and IRS-1, J Biol Chem, 271, 24300, 10.1074/jbc.271.39.24300 Sawka-Verhelle, 1996, Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591–786, J Biol Chem, 271, 5980, 10.1074/jbc.271.11.5980 Yamanashi, 1997, Identification of the Abl- and rasGAP-associated 62kDa protein as a docking protein, Dok, Cell, 88, 205, 10.1016/S0092-8674(00)81841-3 Carpino, 1997, p62 (dok): A constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells, Cell, 88, 197, 10.1016/S0092-8674(00)81840-1 Kouhara, 1997, A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway, Cell, 89, 693, 10.1016/S0092-8674(00)80252-4 Xu, 1998, Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adaptor proteins, J Biol Chem, 273, 17987, 10.1074/jbc.273.29.17987 Bork, 1995, A phosphotyrosine interaction domain, Cell, 80, 693, 10.1016/0092-8674(95)90347-X Liu, 1998, Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans, Cell, 93, 961, 10.1016/S0092-8674(00)81202-7 Uemura, 1989, Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos, Cell, 58, 349, 10.1016/0092-8674(89)90849-0 Jaffrey, 1998, CAPON: A protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95, Neuron, 20, 115, 10.1016/S0896-6273(00)80439-0 Gertler, 1993, Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: Prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate, Genes Dev, 7, 441, 10.1101/gad.7.3.441 Howell, 1997, Neuronal position in the developing brain is regulated by mouse disabled-1, Nature, 389, 733, 10.1038/39607 Whitmarsh, 1998, A mammalian scaffold complex that selectively mediates MAP kinase activation, Science, 281, 1671, 10.1126/science.281.5383.1671 Charest, 1996, Phosphotyrosine-independent binding of SHC to the NPLH sequence of murine protein-tyrosine phosphatase-PEST: Evidence for extended phosphotyrosine binding/phosphotyrosine interaction domain recognition specificity, J Biol Chem, 271, 8424, 10.1074/jbc.271.14.8424 Paz, 1996, Interaction between the insulin receptor and its downstream effectors: Use of individually expressed receptor domains for structure/function analysis, J Biol Chem, 271, 6998, 10.1074/jbc.271.12.6998 Fiore, 1995, The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein, J Biol Chem, 270, 30853, 10.1074/jbc.270.52.30853 Borg, 1996, The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein, Mol Cell Biol, 16, 6229, 10.1128/MCB.16.11.6229 Selkoe, 1997, Alzheimer's disease: Genotypes, phenotypes, and treatments, Science, 275, 630, 10.1126/science.275.5300.630 Zhang, 1997, Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain, EMBO J, 16, 6141, 10.1093/emboj/16.20.6141 Borg, 1998, The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion, J Biol Chem, 273, 14761, 10.1074/jbc.273.24.14761 Trommsdorff, 1998, Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein, J Biol Chem, 273, 33556, 10.1074/jbc.273.50.33556 Chen, 1990, NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor, J Biol Chem, 265, 3116, 10.1016/S0021-9258(19)39742-X Rhyu, 1994, Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells, Cell, 76, 477, 10.1016/0092-8674(94)90112-0 Frise, 1996, The Drosophila Numb protein inhibits signaling of the Notch receptor during cell–cell interaction in sensory organ lineage, Proc Natl Acad Sci USA, 93, 11925, 10.1073/pnas.93.21.11925 Yaich, 1998, Functional analysis of the numb phosphotyrosine binding domain using site directed mutagenesis, J Biol Chem, 273, 10381, 10.1074/jbc.273.17.10381 Chien, 1998, Numb-associated kinase interacts with the phosphotyrosine binding domain of Numb and antagonizes the function of Numb in vivo, Mol Cell Biol, 18, 598, 10.1128/MCB.18.1.598 Dho, 1998, The mammalian numb phosphotyrosine-binding domain: Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX, J Biol Chem, 273, 9179, 10.1074/jbc.273.15.9179 Lu, 1998, Partner of Numb colocalizes with Numb during mitosis and directs Numb asymmetric localization in Drosophila neural and muscle progenitors, Cell, 95, 225, 10.1016/S0092-8674(00)81753-5 Borg, 1998, Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting, J Biol Chem, 273, 31633, 10.1074/jbc.273.48.31633 Okamoto, 1997, Mints, Munc18-interacting proteins in synaptic vesicle exocytosis, J Biol Chem, 272, 31459, 10.1074/jbc.272.50.31459 Butz, 1998, A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain, Cell, 94, 773, 10.1016/S0092-8674(00)81736-5 Cho, 1992, The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein, Neuron, 9, 929, 10.1016/0896-6273(92)90245-9 Fanning, 1998, PDZ domains and the formation of protein networks at the plasma membrane, Curr Top Microbiol Immunol, 228, 209 Kim, 1995, Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases, Nature, 378, 85, 10.1038/378085a0 Kornau, 1995, Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95, Science, 269, 1737, 10.1126/science.7569905 Doyle, 1996, Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ, Cell, 85, 1067, 10.1016/S0092-8674(00)81307-0 Kim, 1997, Polarized signaling: Basolateral receptor localization in epithelial cells by PDZ-containing proteins, Curr Opin Cell Biol, 9, 853, 10.1016/S0955-0674(97)80088-9 Kaech, 1998, The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells, Cell, 94, 761, 10.1016/S0092-8674(00)81735-3 Hoskins, 1996, The C. elegans vulval induction gene lin-2 encodes a member of the MAGUK family of cell junction proteins, Development, 122, 97, 10.1242/dev.122.1.97 Kim, 1997, GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules, J Cell Biol, 136, 669, 10.1083/jcb.136.3.669 Hata, 1996, CASK: A novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins, J Neurosci, 16, 2488, 10.1523/JNEUROSCI.16-08-02488.1996 Simske, 1996, LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction, Cell, 85, 195, 10.1016/S0092-8674(00)81096-X Rongo, 1998, LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia, Cell, 94, 751, 10.1016/S0092-8674(00)81734-1 Borg, 1999, Molecular analysis of the X11-mLin-2/CASK complex in brain, J Neurosci, 19, 1307, 10.1523/JNEUROSCI.19-04-01307.1999 Cohen, 1998, Human CASK/LIN-2 binds syndecan-2 and protein 4.1 and localizes to the basolateral membrane of epithelial cells, J Cell Biol, 142, 129, 10.1083/jcb.142.1.129 Le Gall, 1995, Epithelial cell polarity: New perspectives, Semin Nephrol, 15, 272 Li, 1997, High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif, Proc Natl Acad Sci USA, 94, 7204, 10.1073/pnas.94.14.7204 Sudol, 1995, Characterization of a novel protein-binding module: The WW domain, FEBS Lett, 369, 67, 10.1016/0014-5793(95)00550-S Dickens, 1997, A cytoplasmic inhibitor of the JNK signal transduction pathway, Science, 277, 693, 10.1126/science.277.5326.693