Synthesis of analogs of l-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells

European Journal of Pharmaceutical Sciences - Tập 16 - Trang 1-13 - 2002
Gerda Marie Friedrichsen1, Weiqing Chen2, Mikael Begtrup1, Chao-Pin Lee3, Philip L Smith3, Ronald T Borchardt2
1Department of Medicinal Chemistry, The Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark
2Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, KS 66047, USA
3GlaxoSmithKline, Collegeville, PA 19426, USA

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