High rehospitalization rate in alcohol-induced psychotic disorder

Springer Science and Business Media LLC - Tập 263 - Trang 309-313 - 2012
Michael Soyka1,2, Bernd Helten3, Marcus Cleves3, Peggy Schmidt1
1Private Hospital Meiringen, Willigen, Meiringen, Switzerland
2Department of Psychiatry, Ludwig Maximilian University, Munich, Germany
3BARMER GEK, Berlin, Germany

Tóm tắt

Little is known about the prevalence and in particular the outcome of alcohol-induced psychotic disorder (AIPD). Data from hospital statistics of the BARMER GEK, one of the major health insurance companies in Germany, show a low overall prevalence of AIPD. An analysis of readmission rates for patients hospitalized for AIPD in 2005 (N = 462) and 2006 (N = 404) for the period up to 2010 revealed very high readmission rates. Only a minority of patients were without relapse [144 (31.2 %) of the 2005 sample; 152 (37.6 %) of the 2006 sample]. Thus, AIPD appears to be a rare complication of the alcohol use disorder but to have an extremely high rehospitalization rate, probably indicating a more chronic course and worse prognosis than previously thought. More follow-up studies are needed to elucidate this syndrome.

Tài liệu tham khảo

Hasin DS, Tsai WY, Endicott J et al (1996) Five-year course of major depression: effects of comorbid alcoholism. J Affect Disord 41:63–70 Pirkola SP, Poikolainen K, Lonnqvist JK (2006) Currently active and remitted alcohol dependence in a nationwide adult general population—Results from the Finnish Health 2000 study. Alcohol Alcohol 41:315–320 Kessler RC, Avenevoli S, Costello EJ et al (2011) Prevalence, persistence, and sociodemographic correlates of DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement. Arch Gen Psychiatry 69(4):372–380 Rehm J, Mathers C, Popova S et al (2009) Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 373:2223–2233 Cutting J (1978) A reappraisal of alcoholic psychoses. Psychol Med 8:285–295 Glass IB (1989) Alcoholic hallucinosis: a psychiatric enigma–1. The development of an idea. Br J Addict 84:29–41 Glass IB (1989) Alcoholic hallucinosis: a psychiatric enigma–2. Follow-up studies. Br J Addict 84:151–164 Surawicz FG (1980) Alcoholic hallucinosis: a missed diagnosis. Differential diagnosis and management. Can J Psychiatry 25:57–63 Soyka M (1990) Psychopathological characteristics in alcohol hallucinosis and paranoid schizophrenia. Acta Psychiatr Scand 81:255–259 Soyka M (1995) Pathophysiological mechanisms possibly involved in the development of alcohol hallucinosis. Addiction 90:289–290 Jordaan GP, Nel DG, Hewlett RH et al (2009) Alcohol-induced psychotic disorder: a comparative study on the clinical characteristics of patients with alcohol dependence and schizophrenia. J Stud Alcohol Drugs 70:870–876 Soyka M (2009) Alcohol-induced psychotic disorder [in German]. Nervenheilkunde 28:533–537 Soyka M (2010) Alcohol-induced psychotic disorders—A review [in German]. Suchtmed 12:21–28 Borg S, Kvande H, Valverius P (1986) Clinical conditions and central dopamine metabolism in alcoholics during acute withdrawal under treatment with different pharmacological agents. Psychopharmacology 88:12–17 Fadda F, Mosca E, Colombo G et al (1989) Effect of spontaneous ingestion of ethanol on brain dopamine metabolism. Life Sci 44:281–287 Kendler KS (1985) A twin study of individuals with both schizophrenia and alcoholism. Br J Psychiatry 147:48–53 Schuckit MA, Winokur G (1971) Alcoholic hallucinosis and schizophrenia: a negative study. Br J Psychiatry 119:549–550 Scott DF (1967) Alcoholic hallucinosis—An aetiological study. Br J Addict Alcohol Other Drugs 62:113–125 Jordaan GP, Warwick JM, Hewlett R et al (2010) Resting brain perfusion in alcohol-induced psychotic disorder: a comparison in patients with alcohol dependence, schizophrenia and healthy controls. Prog Neuropsychopharmacol Biol Psychiatry 34:479–485 Jordaan GP, Warwick JM, Nel DG et al (2012) Alcohol-induced psychotic disorder: brain perfusion and psychopathology-before and after anti-psychotic treatment. Metab Brain Dis 27:67–77 Kitabayashi Y, Narumoto J, Shibata K et al (2007) Neuropsychiatric background of alcohol hallucinosis: a SPECT study. J Neuropsychiatry Clin Neurosci 19:85 Soyka M, Dresel S, Horak M et al (2000) PET and SPECT findings in alcohol hallucinosis: case report and super-brief review of the pathophysiology of this syndrome. World J Biol Psychiatry 1:215–218 Soyka M, Koch W, Tatsch K (2005) Thalamic hypofunction in alcohol hallucinosis: FDG PET findings. Psychiatry Res 139:259–262 Victor M, Adams RD (1953) The effect of alcohol on the nervous system. Res Publ Assoc Res Nerv Ment Dis 32:526–573 Tsuang JW, Irwin MR, Smith TL et al (1994) Characteristics of men with alcoholic hallucinosis. Addiction 89:73–78 Soyka M (2008) Prevalence of alcohol-induced psychotic disorders. Eur Arch Psychiatry Clin Neurosci 258:317–318 Soyka M (2008) Prevalence of delirium tremens. Am J Addict 17:452 Perala J, Kuoppasalmi K, Pirkola S et al (2010) Alcohol-induced psychotic disorder and delirium in the general population. Br J Psychiatry 197:200–206 Mattisson C, Bogren M, Ojehagen A et al (2011) Mortality in alcohol use disorder in the Lundby Community Cohort—A 50 year follow-up. Drug Alcohol Depend 118:141–147 de Millas W, Haasen C (2007) Treatment of alcohol hallucinosis with risperidone. Am J Addict 16:249–250 Soyka M, Botschev C, Volcker A (1992) Neuroleptic treatment in alcohol hallucinosis—No evidence for increased seizure risk. J Clin Psychopharmacol 12:66–67 Aliyev NA, Aliyev ZN (2005) Application of glycine in acute alcohol hallucinosis. Hum Psychopharmacol 20:591–594 Aliyev ZN, Aliyev NA (2008) Valproate treatment of acute alcohol hallucinosis: a double-blind, placebo-controlled study. Alcohol Alcohol 43:456–459