Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

Journal of Clinical Investigation - Tập 126 Số 8 - Trang 3036-3052 - 2016
Meenakshi Hegde1,2,3,4,5, Malini Mukherjee2,6,5, Zakaria Grada1,2,4,5, Antonella Pignata1,2,4,5, Daniel Landi1,2,4,5, Shoba A. Navai1,2,4,5, Amanda Wakefield1,2,4,5, Kristen Fousek1,2,3,4,5, Kevin Bielamowicz1,2,4,5, Kevin Chow1,2,4,5, Vita S. Brawley1,2,4,5, Tiara T. Byrd1,2,3,4,5, Simone Krebs1,2,4,5, Stephen Gottschalk1,2,3,4,5, Winfried S. Wels7, Matthew L. Baker8, Gianpietro Dotti1,4,5, Maksim Mamonkin1,2,4,5, Malcolm K. Brenner1,2,4,5, Jordan S. Orange2,6,5, Nabil Ahmed1,2,3,4,5
1Center for Cell and Gene Therapy, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, Texas, USA
2‡Department of Pediatrics and
3Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, USA
4Texas Children's Cancer and Hematology Centers and
5Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, USA;
6Texas Children's Hospital Center for Human Immunobiology, Houston, Texas, USA.
7Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany
8National Center for Macromolecular Imaging, Department of Biochemistry, Baylor College of Medicine, Houston, Texas, USA.

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Journal of Clinical Investigation

Tập 126 Số 8

3036-3052

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