The GABAB receptor antagonist CGP36742 improves learned helplessness in rats

European Journal of Pharmacology - Tập 381 - Trang 1-7 - 1999
Yutaka Nakagawa1, Atsushi Sasaki1,2, Toshiyuki Takashima1,2
1Tsukuba Research Laboratories Experimental Biomedical Research (Jisseiken), 8-5-1, Chuo, Ami-machi, Inashiki-gun, Ibaraki 300-03, Japan
2Kashima Laboratories, Mitsubishi Chemical Safety Institute, Hasaki, Kashima, Ibaraki 314-0255, Japan

Tài liệu tham khảo

Banerjee, 1977, Development of β-adrenergic receptor subsensitivity by antidepressants, Nature, 268, 455, 10.1038/268455a0 Barnes, 1989, 5-HT3 receptors mediate inhibition of acetylcholine release in cortical tissue, Nature, 338, 762, 10.1038/338762a0 Bittiger, 1996, GABAB receptor antagonists: potential therapeutic applications, 297 Blandina, 1989, Release of endogenous dopamine by stimulation of 5-hydroxytryptamine3 receptors in rat striatum, J. Pharmacol. Exp. Ther., 251, 803 Bowery, 1993, GABAB receptor pharmacology, Annu. Rev. Pharmacol. Toxicol., 33, 109, 10.1146/annurev.pa.33.040193.000545 Carletti, 1993, The GABAB antagonist CGP36742 enhances spatial learning performance and antagonises baclofen-induced amnesia in mice, Br. J. Pharmacol., 109 Fan, 1994, Effects of antidepressants on the inward current mediated by 5-HT3 receptors in rat nodose ganglion neurones, Br. J. Pharmacol., 112, 741, 10.1111/j.1476-5381.1994.tb13140.x Freund, 1990, Serotonergic control of the hippocampus via local inhibitory interneurons, Proc. Natl. Acad. Sci. U.S.A., 87, 8501, 10.1073/pnas.87.21.8501 Froestl, 1995, Phosphinic acid analogues of GABA: 2. Selective, orally active GABAB antagonists, J. Med. Chem., 38, 3313, 10.1021/jm00017a016 Gray, 1987, Increased GABAB receptor function in mouse frontal cortex after repeated administration of antidepressant drugs or electroconvulsive shocks, Br. J. Pharmacol., 92, 357, 10.1111/j.1476-5381.1987.tb11331.x Gray, 1987, Hypothermia induced by baclofen, a possible index of GABAB receptor function in mice, is enhanced by antidepressant drugs and ECS, Br. J. Pharmacol., 92, 863, 10.1111/j.1476-5381.1987.tb11392.x Greenshaw, 1993, Behavioural pharmacology of 5-HT3 receptor antagonists: a critical update on therapeutic potential, Trends Pharmacol. Sci., 14, 265, 10.1016/0165-6147(93)90128-7 Johnston, 1997, Molecular biology, pharmacology and physiology of GABAC receptors, 297 Joly, 1987, Correlation between the behavioral effect of desipramine and GABAB receptor regulation in the olfactory bulbectomized rat, Br. J. Pharmacol., 90 Knight, 1996, The pharmacology of adenylyl cyclase modulation by GABAB receptors in rat brain slices, Neuropharmacology, 35, 703, 10.1016/0028-3908(96)84642-9 Lloyd, 1990, Antidepressants and GABAB site upregulation, 297 Lloyd, 1986, Decrease in GABAB binding in the frontal cortex of olfactory bulbectomized rats, Br. J. Pharmacol., 87 Lloyd, 1985, Upregulation of γ-aminobutyric acid (GABA)B binding sites in rat frontal cortex: a common action of repeated administration of different classes of antidepressants and electroshock, J. Pharmacol. Exp. Ther., 235, 191 Lucchelli, 1995, The interaction of antidepressant drugs with central and peripheral (enteric) 5-HT3 and 5-HT4 receptors, Br. J. Pharmacol., 114, 1017, 10.1111/j.1476-5381.1995.tb13307.x Martin, 1989, Decreased GABAB receptors in helpless rats: reversal by tricyclic antidepressants, Neuropsychobiology, 22, 220, 10.1159/000118620 Martin, 1992, 5-HT3 receptor antagonists reverse helpless behaviour in rats, Eur. J. Pharmacol., 212, 73, 10.1016/0014-2999(92)90074-E Matsumoto, 1989, GABA receptors: are cellular differences reflected in function?, Brain Res. Rev., 14, 203, 10.1016/0165-0173(89)90001-5 Meyer, 1991, Effects of p-chloroamphetamine on release of [3H]γ-aminobutyric acid from slices of rat caudate–putamen, Eur. J. Pharmacol., 196, 189, 10.1016/0014-2999(91)90427-R Nakagawa, 1997, The GABAB receptor antagonist CGP36742 attenuates the baclofen- and scopolamine-induced deficit in Morris water maze task in rats, Brain Res., 766, 101, 10.1016/S0006-8993(97)00529-5 Nakagawa, 1996, Involvement of GABAB receptor systems in action of antidepressants: baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats, Brain Res., 709, 215, 10.1016/0006-8993(95)01273-7 Nakagawa, 1996, Involvement of GABAB receptor systems in action of antidepressants: II. Baclofen attenuates the effect of desipramine whereas muscimol has no effect in learned helplessness paradigm in rats, Brain Res., 728, 225, 10.1016/0006-8993(96)00413-1 Nakagawa, 1996, Involvement of GABAB receptor systems in experimental depression: baclofen but not bicuculline exacerbates helplessness in rats, Brain Res., 741, 240, 10.1016/S0006-8993(96)00929-8 Nakagawa, 1998, The 5-HT3 receptor agonist attenuates the action of antidepressants in the forced swim test in rats, Brain Res., 786, 189, 10.1016/S0006-8993(97)01459-5 Olpe, 1993, The actions of orally active GABAB receptor antagonists on GABAergic transmission in vivo and in vitro, Eur. J. Pharmacol., 233, 179, 10.1016/0014-2999(93)90048-M Pilc, 1984, Chronic antidepressants and GABA “B” receptors: a GABA hypothesis of antidepressant drug action, Life Sci., 35, 2149, 10.1016/0024-3205(84)90515-0 Post, 1991, Lack of beneficial effects of l-baclofen in affective disorder, Int. Clin. Psychopharmacol., 6, 197, 10.1097/00004850-199100640-00001 Pratt, 1990, Autoradiographic analysis of GABAB receptors in rat frontal cortex following chronic antidepressant administration, 319 Pratt, 1993, Repeated administration of desipramine and a GABAB receptor antagonist, CGP36742, discretely up-regulates GABAB receptor binding sites in rat frontal cortex, Br. J. Pharmacol., 110, 724, 10.1111/j.1476-5381.1993.tb13872.x Redrobe, 1997, Partial role of 5-HT2 and 5-HT3 receptors in the activity of antidepressants in the mouse forced swimming test, Eur. J. Pharmacol., 325, 129, 10.1016/S0014-2999(97)00115-5 Ropert, 1991, Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro, J. Physiol., 441, 121, 10.1113/jphysiol.1991.sp018742 Staubli, 1994, Serotonin controls the magnitude of LTP induced by theta bursts via an action on NMDA-receptor-mediated responses, Brain Res., 643, 10, 10.1016/0006-8993(94)90003-5 Staubli, 1995, Effects of 5-HT3 receptor antagonism on hippocampal theta rhythm, memory, and LTP induction in the freely moving rat, J. Neurosci., 15, 2445, 10.1523/JNEUROSCI.15-03-02445.1995 Suzdak, 1985, Parallel changes in the sensitivity of γ-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs: a possible role in affective disorders, Neuropharmacology, 24, 217, 10.1016/0028-3908(85)90077-2 Suzdak, 1986, Effect of chronic imipramine or baclofen on GABAB binding and cyclic AMP production in cerebral cortex, Eur. J. Pharmacol., 131, 129, 10.1016/0014-2999(86)90526-1 Szekely, 1987, Effect of a protracted antidepressant treatment on signal transduction and [3H](−)-baclofen binding at GABAB receptors, J. Pharmacol. Exp. Ther., 243, 155